Carboxylic Acids

<p>Stability Moisture Sensitive<br>Applications 2-(Dimethoxyphosphoryl)acetic acid<br></p>

<p>Applications tert-Butyl N-Tosyloxycarbamate is a sulfhydroxylamine that, when used in combination with Lithium, functions as an efficient electrophile in the amination of chiral amide cuprate compounds. tert-Butyl N-Tosyloxycarbamate is also used as a reagent to synthesize N-Boc protected primary amines (e.g. N-Boc-ethylenediamine [B655000]).<br>References Chiba, S. &amp; Narasaka, K.: Amin. Grou. Chem: Synth. Life Sci., No vol. given (2008); Gallou, I. &amp; Senanayake, C.: Chem. Rev.: 106, 2843 (2006); Genet, J., et al.: Tetrahedron Lett., 32, 2359 (1991); Zheng, N., et al.: ChemInform, 28, No pp. given (1997)<br></p>

<p>Applications 2-Acetylphenylboronic Acid is a reactant used in the synthesis of potent, selective phenylimidazole-based tissue factor/factor VIIa (FVIIa) inhibitors.<br>References Glunz, P.W., et. al.: Bioorg. Med. Chem. Lett., 25, 21699 (2015)<br></p>

<p>Applications Vinblastine N'b-Oxide Maleic Acid Salt is an analog of vinca alkaloid n-oxide that is used for the treatment of hyperproliferative diseases.<br></p>

<p>Applications 7-Chlorokynurenic acid is an NMDA receptor antagonist and inhibitor of EAAT.<br></p>

<p>Applications Methyl Isocyanoacetate, is used in the Cu-catalyzed, diastereoselective synthesis of oxazolines (O846550).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ideguchi, T., et al.: J. American Chem. Soc., 135, 12568 (2013);<br></p>

<p>Applications 9H-xanthen-9-ylacetic acid (cas# 1217-58-9) is a useful research chemical.<br></p>

<p>Applications 6-Heptynoic Acid is used as a reagent in organic synthesis, inlcuding that of some novel triazole derivatives which display antiproliferative activity and also of acetylenic fatty acids and their esters.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pertino, M., et al.: Molecules, 19, 2523 (2014); Nakatani, M., et al.: B. Chem. Soc. Jpn., 59, 3535 (1986);<br></p>

<p>Stability Moisture Sensitive<br>Applications 5,5-Dibromobarbituric Acid (cas# 511-67-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Dihydroxyfumaric Acid Dimethyl Ester is used in the reactions involving of β-sheet formation.<br>References Kemp, D. et al.: J. Org. Chem., 55, 4650 (1990);<br></p>

<p>Applications 2-(Aminosulfonyl)benzoic Acid can be used as reactant/reagent in synthesis and pharmacological activity of γ-(phenyloxamido)- and γ-(phenylsulfonyloxamido)butanoic acids.<br>References Georgiyants, V. A., et al.: Farmatsevtichnii Zhurnal, 2, 34 (2010);<br></p>

<p>Applications 5-(Diphenylphosphinyl)pentanoic Acid, can be used for the preparation of praseodymium coordination polymers with diphenylphosphorylvalerate ligand. It is also a by product in the preparation of prostaglandin analogs.<br>References Spichal, Z., et al.: Polyhedron, 48, 99 (2012); Zhao Y. et al.: PCT Int. Appl. 43pp.Patent, 2016<br></p>

<p>Applications 3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carboxylic acid (cas# 134997-87-8) is a useful research chemical.<br></p>

<p>Applications Phenyl[2-phenylthio)phenyl]carbamate is an intermediate utilized for the synthesis of Quetiapine Hemifumarate (Q510000), an atypical antipsychotic agent used for the treatment of patients with schizophrenia, biopolar disorder and to treat major depressive disorder.<br>References Niphade, N.C., et al.: Org. Proc. Rsch. Dev., 13, 792 (2009); Stolarczyk, E.U., et al.: Pharm. Dev. Tech., 14, 27 (2009);<br></p>