Carboxylic Acids

Applications Formamidine Acetate is a versatile reactant used in the tetrazine-based cycloadditions applied to pretargeted live cell imaging with norbornene modified monoclonal antibody.
References Devaraj, N., et al.: Bioconjugate Chem., 19, 2297 (2008);

Applications 1,2-Diaminopropane-N,N,N',N'-tetraacetic Acid is an aminopolycarboxylic acids found at ultra-trace levels in water; Also, it is used in the construction of Eu3+ ion-selective membrane electrode as suitable ionophore.
References Nette, D., et al.: Anal. Chim. Acta, 884, 124-132 (2015); Abedi, M. R., et al.: E-J. Chem., 8, S467-S473 (2011)

Applications 3-Formylbenzene-1,2-disulfonoic Acid is derived from 5,6-Difluoro Anthranilic Acid (D445550), which is used in the preparation of 2-[[2-(phenylamino)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide derivatives as inhibitors of IGF-1R and IR receptor tyrosine kinase as anticancer agents.
References Rubinstein, E., et al.: Chemotherapy, 47, 3 (2001), Grohs, P., et al.: Antimicrob. Agents Chemother., 47, 3542 (2003),

Applications Methyl Isocyanoacetate, is used in the Cu-catalyzed, diastereoselective synthesis of oxazolines (O846550).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ideguchi, T., et al.: J. American Chem. Soc., 135, 12568 (2013);

Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.
References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)

Applications 4-(Aminomethyl)-Cyclohexanecarboxylic Acid (cas# 701-54-2) is a useful research chemical.

Applications Phenylmethyl ester N-[(3aS,4R,6S,6aR)-tetrahydro-6-hydroxy-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]-Carbamic acid is a useful chiral building block. It has been used in the synthesis of all-cis carbocyclic precursor of ticagrelor via oxidation/stereoselective reduction sequences.
References Wlodarczyk, J.; et al.: Tet. Lett., 56, 6093 (2015).

Applications 2-hydroxy-5-[2-(4-hydroxyphenyl)propan-2-yl]benzoic acid (cas# 101949-49-9) is a useful research chemical.

Applications (6,7-dimethoxy-4-oxoquinazolin-3(4H)-yl)acetic acid (cas# 877140-09-5) is a useful research chemical.

Applications 2-amino-3-hydroxy-3-phenylpropanoic acid (cas# 7695-56-9) is a useful research chemical.

Applications Cyclopentylacetic acid is a reagent the synthesis of Cyclopentamine (C988355), which is a vasoconstrictor that acts as a releasing agent of the neurotransmitters norepinephrine, epinephrine and dopamine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schmidt, J.L. et al.: J. Pharmacol. Exp. Ther., 145, 83 (1964); Iversen, L.L.: J. Pharm. Pharmacol., 16, 435 (1964);

Applications 5-Oxo-1,3-dioxolane-4,4-diacetic Acid is used as a reagent to synthesize vibrioferrin, a siderophore. It can also be used as a building block of lipophilic isosteres of nucleoside triphosphates which are potential inhibitors of HIV reverse transcriptase.
References Takeuchi, Y., et al.: Chem. Pharm. Bull., 47, 459 (1999); Weaver, R., et al.: Bioorg. Med. Chem. Lett., 6, 2405 (1996)

Applications 6-Hydrazinonicotinic acid