Benzenes

<p>2,6-Dimethylbenzaldehyde is a colorless liquid with a sweet odor. It is used in the synthesis of fatty acids and as an intermediate for other compounds. This chemical has significant cytotoxicity against leukemia cells, and is used in the production of acrylonitrile. 2,6-Dimethylbenzaldehyde can be synthesized by reacting an amine with an acyl chloride, followed by hydrolysis of the resulting ester. A contactor is usually added to facilitate the reaction. The reaction can also be carried out in the presence of a phosphorane or organic solvent.<br>2,6-Dimethylbenzaldehyde can be hydrogenated to produce 2,4-dimethylaniline and 2,4,6-trimethylaniline.</p>

<p>2,4-Dihydroxybenzoic acid (2,4-DB) is a metabolite of salicylic acid. It is used as an intermediate in the production of various drugs and dyes. 2,4-DB has been shown to be effective against hepatic steatosis induced by hydrogen fluoride in mice. This drug also inhibits mitochondrial membrane potential and DNA binding activity in human serum. 2,4-DB can bind to the α subunit of mitochondrial ATPase and act as a competitive inhibitor for p-hydroxybenzoic acid which is essential for the activation of this enzyme. The x-ray diffraction data from crystalline 2,4-DB shows that this compound binds to dna with coordination geometry that resembles that of salicylic acid. The kinetic studies have shown that 2,4-DB reacts noncompetitively with nonsteroidal anti-inflammatory drugs (NSAIDs).</p>