Pharmaceutical Standards
Pharmaceutical standards are a comprehensive set of reference materials essential for ensuring the safety, efficacy, and quality of pharmaceutical products. This category includes standards for active pharmaceutical ingredients (APIs), which are the core components responsible for therapeutic effects. Additionally, it covers compounds and metabolites relevant to both the pharmaceutical and veterinary industries, providing benchmarks for the accurate measurement and analysis of these substances. Nitrosamine control standards are crucial for detecting and mitigating potentially harmful nitrosamines in drug formulations. Toxicology standards help assess the safety and potential adverse effects of pharmaceutical compounds. Furthermore, enzyme activators and inhibitors standards are vital for research and development, enabling precise studies of biochemical pathways and drug mechanisms. These pharmaceutical standards are indispensable tools for regulatory compliance, quality control, and research, ensuring that pharmaceutical products meet stringent safety and effectiveness criteria.
Subcategories of "Pharmaceutical Standards"
- APIs for research and impurities(273,647 products)
- Enzyme Activators and Inhibitors(2,827 products)
- Nitrosamines(2,605 products)
- Pharmaceutical and Veterinary Compounds and Metabolites(2,602 products)
- Toxicology(13,652 products)
Found 7836 products of "Pharmaceutical Standards"
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Adenosine-5',5''-d2
CAS:Controlled Product<p>Applications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formula:C10H11D2N5O4Color and Shape:White SolidMolecular weight:269.26N1,N12-Diacetylspermine Dihydrochloride
CAS:<p>Stability Hygrscopic<br>Applications N1,N12-Diacetylspermine Dihydrochloride is a diacetylated derivative of Spermine (S680510) and is recognized as a novel tumor marker in patients with breast and colorectal cancers.<br>References Kato, M., et al.: Anticancer Res., 34, 3053 (2014); Umemori, Y., et al.: Clin. Chim. Acta, 411, 1894 (2010); Kawakita, M., et al.: J. Biochem., 139, 315 (2006); Hiramatsu, K., et al.: Clin. Cancer Res., 11, 2986 (2005)<br></p>Formula:C14H32Cl2N4O2Color and Shape:NeatMolecular weight:359.347-Bromobenz[a]anthracene
CAS:Controlled Product<p>Applications 7-Bromobenz[a]anthracene (cas# 32795-84-9) is a useful research chemical.<br></p>Formula:C18H11BrColor and Shape:NeatMolecular weight:307.182,2'-((4-Aminophenyl)azanediyl)diethanol Sulfate
CAS:Controlled ProductFormula:C10H16N2O2·H2O4SColor and Shape:White To Off-WhiteMolecular weight:294.32472,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5
CAS:Controlled Product<p>Applications 2,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5 is the isotope labelled analog of 2,3,4-Trihydroxybenzophenone; a trihydroxy derivative of Benzophenone (B204980) which is a compound used in the manufacturing of antihistamines, hypnotics, and insecticides.<br>References Wallace, W., et al.: Environ. Toxicol. Chem., 19, 962 (2000); Hayashi, T., et al.: Toxicol. Lett., 167, 1 (2006); Bechard, K., et al.: Aquat. Toxicol., 90, 310 (2008)<br></p>Formula:C13D5H5O4Color and Shape:NeatMolecular weight:235.247Bromfenac Sodium Sesquihydrate
CAS:Controlled Product<p>Applications Bromfenac is a non-steroidal anti-inflammatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), MacDonald, J., et al.: Toxicol. Sci., 110, 40 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Formula:C15H11BrNO3·2Na·3H2OColor and Shape:Light YellowMolecular weight:766.34trans-α-Asarone
CAS:Controlled ProductFormula:C12H16O3Color and Shape:White To Off-WhiteMolecular weight:208.25Melagatran
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic.<br>References Dewanjee, M., et al.: J. Nucl. Med., 22, 981 (1981), Goodman, S., et al.: J. Biomed. Mater. Res., 45, 240 (1999), Carlsson, S., et al.: Thromb. Res., 115, 9 (2005),<br></p>Formula:C22H31N5O4Color and Shape:NeatMolecular weight:429.515-Chloronaphthalene-1-sulfonyl Chloride
CAS:Controlled Product<p>Applications 5-Chloronaphthalene-1-sulfonyl Chloride (cas# 6291-07-2) is a compound useful in organic synthesis.<br></p>Formula:C10H6Cl2O2SColor and Shape:NeatMolecular weight:261.12Benoxaprofen
CAS:Controlled Product<p>Applications A non-steroidal anti-inflammatory ophthalmic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mathur, K., et al.: Bioorg. Med. Chem., 11, 1915 (2003), Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007), Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009),<br></p>Formula:C16H12ClNO3Color and Shape:NeatMolecular weight:301.72Petromyzonol 24-Sulfate Sodium Salt
CAS:Controlled ProductFormula:C24H41O7S·NaColor and Shape:NeatMolecular weight:496.63Desacetyl Diltiazem
CAS:<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Formula:C20H24N2O3SColor and Shape:White To BrownMolecular weight:372.48Piretanide
CAS:<p>Applications High-ceiling loop diuretic; structurally related to Bumetanide (B689550). Diuretic.<br>References Merkel, W., et al.: Eur. J. Med. Chem., 11, 399 (1976), Pozet, N., et al.: Br. J. Clin. Pharmacol., 9, 577 (1980), Clissold, S.P., et al.: Drugs, 29, 489 (1985),<br></p>Formula:C17H18N2O5SColor and Shape:Light Yellow SolidMolecular weight:362.402,3-Dibromoanthracene
CAS:Controlled Product<p>Applications 2,3-Dibromoanthracene is a useful synthetic intermediate. It is used to synthesize various acenes and acene derivatives such as Acenaphth[1,2-b]anthracene (A130745) which is mutagenic.<br>References Toyota, S., et al.: Sci. Syn., 45, 745 (2010); Durant, J., et al.: Mutat. Res-Genet. Tox., 371, 123 (1996)<br></p>Formula:C14H8Br2Color and Shape:NeatMolecular weight:336.02Zolpidem Phenyl-4-carboxylic Acid
CAS:<p>Applications A major metabolite of Zolpidem.<br>References Crestani, F., et al.: Br. J. Pharmacol., 131, 1251 (2000), Li, Q., et al.: Bioorg. Med. Chem. Lett., 12, 465 (2002), Goulle, J., et al.: Ther. Drug Monit., 26, 206 (2004), Ohkanda, J., et al.: J. Med. Chem., 47, 432 (2004), Blackaby, W., et al.: Bioorg. Med. Chem. Lett., 16, 1175 (2006),<br></p>Formula:C19H19N3O3Color and Shape:Off-White To Light BeigeMolecular weight:337.37Dimethyl 2,7-Naphthalenedicarboxylate
CAS:Controlled Product<p>Applications Dimethyl 2,7-Naphthalenedicarboxylate (cas# 2549-47-5) is a useful research chemical.<br></p>Formula:C14H12O4Color and Shape:Off White To Light YellowMolecular weight:244.2434,4’-Bis(4”-aminobenzenesulfonyl) Diphenyl Ether Dihydrochloride
CAS:<p>Applications The diamino arylene disulfones used in polyamido polysulfone thermoplastics and intermediates.<br></p>Formula:C24H20N2O5S2•2HClColor and Shape:NeatMolecular weight:553.47Ferulic Acid-d3 4-O-Sulfate Disodium Salt
CAS:Controlled Product<p>Applications Ferulic Acid-d3 4-O-Sulfate Disodium Salt, is a labeled analogue of Ferulic Acid 4-O-Sulfate Disodium Salt (F308920), a metabolite of Ferulic Acid. Ferulic Acid 4-O-Sulfate is one of the circulating metabolites in human plasma after consumption polyphenol-rich juice drink.<br>References Fumeaux, R., et al.: Org. Biomol. Chem., 8, 5199 (2010); Mullen, W., et al.: J. Agric. Food Chem., 58, 2586 (2010);<br></p>Formula:C10D3H5Na2O7SColor and Shape:NeatMolecular weight:321.2293-(4-(2,3-Epoxypropoxy)phenyl)propionic Acid Methyl Ester
CAS:<p>Applications 3-(4-(2,3-Epoxypropoxy)phenyl)propionic Acid Methyl Ester is an intermediate in the synthesis of N-Ethyl Esmolol (E918045), which is an impurity of esmolol (E668000), which is a cardioselective β-adrenergic blocker. Antiarrhythmic.<br>References Gorczynski, R.J., et al.: J. Cardiovasc. Pharmacol., 5, 668 (1983), Yacobi, A., et al.: J. Pharm. Sci., 72, 711 (1983), Benfield, P., et al.: Drugs, 33, 392 (1987)<br></p>Formula:C13H16O4Color and Shape:NeatMolecular weight:236.26Bromantane
CAS:Controlled Product<p>Applications Bromantane is an adamantane derivative used as an anxiolytic agent.<br>References Reznikov, A., et al.: Endokrinologie, 73, 11 (1979), Grekhova, T., et al.: Bull. Eksp. Biol. Med., 119, 302 (1995),<br></p>Formula:C16H20BrNColor and Shape:White To Off-WhiteMolecular weight:306.24Chenodeoxycholic acid-3-β-D-glucuronide
CAS:Controlled ProductFormula:C30H48O10Color and Shape:White To Off-WhiteMolecular weight:568.7Allo-3α-tetrahydro Cortisol
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Cortisol (H714615).<br>References Quinkler, M., et al.: J. Clin. Endocrinol. Metab., 88, 2384 (2003), Draper, N., et al.: J. Endocrinol., 186, 251 (2005), Kotlowska, A., et al.: Clin. Biochem., 42, 448 (2009),<br></p>Formula:C21H34O5Color and Shape:Off White SolidMolecular weight:366.49Prasugrel Thiolactone-d5 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications A labelled inactive metabolite of Prasugrel (P701150).<br>References Sugidachi, A., et al.: Br. J. Pharmacol., 129, 1439 (2000); Takahashi, S., et al.: J. Pharm. Sci., 97, 5434 (2008); Williams, E., et al.: Drug Metab. Dispos., 36, 1227 (2008); Hagihara, K., et al.: Xenobiotica, 39, 218 (2009);<br></p>Formula:C18H13D5FNO2SColor and Shape:NeatMolecular weight:336.435L-Homoserine Lactone Hydrobromide
CAS:Controlled Product<p>Applications L-Homoserine Lactone Hydrobromide is a reactant in the synthesis of tritium labeled and photoactivatable N-acyl-L-homoserine lactones.<br>References Jakubczyk, D., et. al.: Eur. J. Org. Chem., 592, 2014 (2014)<br></p>Formula:C4H7NO2·HBrColor and Shape:NeatMolecular weight:314.419Isovaleric Acid Methyl Ester
CAS:Controlled Product<p>Applications Isovaleric Acid Methyl Ester is a volatile compound found in Albion and Juliette strawberry fruits that contributes to the flavor of the fruit.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Samykanno, K., et. al.: Sci. Hortic-Amsterdam, 164, 633 (2013)<br></p>Formula:C6H12O2Color and Shape:ColourlessMolecular weight:116.16Betamethasone 6α-Bromo 17-Valerate
Controlled Product<p>Applications Betamethasone 6α-Bromo 17-Valerate is an impurity of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Formula:C27H36BrFO6Color and Shape:NeatMolecular weight:555.47rac-syn N,N-Diethyl Norephedrine
CAS:Controlled Product<p>Applications The main basic metabolite of Diethylpropione.<br>References Banci, F., et al.: Arzneim.-Forsch., 21, 1616 (1971), Mikhailova, D., et al.: Eur. J. Med. Chem., 13, 49 (1978),<br></p>Formula:C13H21NOColor and Shape:NeatMolecular weight:207.31Cyclamic Acid-d11
CAS:Controlled Product<p>Applications Labelled Cyclamic acid. A non-nutritive sweetener.<br>References Taylor, et al.: Food Cosmet. Toxicol., 6, 313 (1968), Brantom, et al.: Food Cosmet. Toxicol., 11, 735 (1973),<br></p>Formula:C6D11H2NO3SColor and Shape:NeatMolecular weight:190.31Biotin Sulfone
CAS:Controlled Product<p>Applications Biotin Sulfone, is derivative of Biotin (B389040), which is a growth factor present in minute amounts in every living cell, and plays an indispensable role in numerous naturally occurring carboxylation reactions.<br>References du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992),<br></p>Formula:C10H16N2O5SColor and Shape:NeatMolecular weight:276.316-Hydroxy Etodolac
CAS:Controlled Product<p>Applications 6-Hydroxy Etodolac is an Etodolac (E933100) metabolite.<br>References Humber, L., et al.: J. Med. Chem., 32, 2582 (1989), Koupai-Abyazani, M., et al.: J. Anal. Toxicol., 23, 200 (1999),<br></p>Formula:C17H21NO4Color and Shape:NeatMolecular weight:303.35Beclomethasone 21-Acetate 17-Propionate
CAS:Controlled Product<p>Impurity Beclomethasone Dipropionate EP Impurity B<br>Applications Beclomethasone 21-Acetate 17-Propionate (Beclomethasone Dipropionate EP Impurity B) is an impurity of Beclomethasone Dipropionate (B131030).<br></p>Formula:C27H35ClO7Color and Shape:NeatMolecular weight:507.02(S)-Ramelteon Metabolite M-II
CAS:Controlled Product<p>Applications S-Ramelteon Metabolite M-II is a metabolite of Ramelteon in serum (M-II).<br>References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004); Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004); Kato, K., et al.: Neuropharmacology, 48, 301 (2005); Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006)<br></p>Formula:C16H21NO3Color and Shape:NeatMolecular weight:275.34N6-Isopentenyladenosine
CAS:<p>Applications N6-Isopentenyladenosine has antiproliferative activity on MCF-7 breast cancer cells.<br>References Rajabi, M. et al.; DNA Cell Biol.; 29, 687 (2010)<br></p>Formula:C15H21N5O4Color and Shape:NeatMolecular weight:335.36Mevastatin Hydroxy Acid Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood.<br>References Endo, A. et al.: Atheroscler. Supp., 5, 39 (2004); Hosobuchi, M. et al.: J. Ferm. Bioeng., 76, 470 (1993);<br></p>Formula:C23H35O6·NaColor and Shape:NeatMolecular weight:430.51Clocortolone Acetate
CAS:Controlled Product<p>Applications Clocortolone Acetate is an intermediate in the synthesis of Clocortolone (C583800), an corticosteroid used in the treatment of skin inflammmation and other skin conditions arising for dermatoses.<br>References Rehm, K. et al.: Pharmaz. Zeit., 127, 888 (1982);<br></p>Formula:C24H30ClFO5Color and Shape:NeatMolecular weight:452.942-Hydroxy Oleic Acid
CAS:Controlled Product<p>Applications An oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive.<br>References Llado, V. et al.: J. Cell. Molec. Med., 14, 659 (2010); Alemany, R. et al.: J. Lip. Res., 47, 1762 (2006); Martinez, J. et al.: J. Pharmacol. Exp. Therap., 315, 466 (2005);<br></p>Formula:C18H34O3Color and Shape:Off White SolidMolecular weight:298.46Androsterone Sulfate Sodium Salt
CAS:Controlled ProductFormula:C19H29O5S·NaColor and Shape:White To Off-WhiteMolecular weight:392.40Betamethasone Tripropionate
CAS:<p>Impurity Betamethasone Dipropionate EP Impurity G<br>Applications Betamethasone Tripropionate (Betamethasone Dipropionate EP Impurity G) is a Betamethasone (B327000) related compound.<br>References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),<br></p>Formula:C31H41FO8Color and Shape:NeatMolecular weight:560.65Hydroxy Urea
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Formula:CH4N2O2Color and Shape:White SolidMolecular weight:76.052,2,6,6-Tetramethyl-4-piperidyl Methacrylate
CAS:Controlled Product<p>Applications It is used as cholesterol-lowering agent.<br>References Bauer, D., et al.: Polym Deg. Stab., 48, 259 (1995), Nakahara, K., et al.: Chem. Physics Lett., 359, 351 (2002),<br></p>Formula:C13H23NO2Color and Shape:WhiteMolecular weight:225.33Betamethasone 9,11-Epoxide 17,21-Dipropionate
CAS:Controlled Product<p>Impurity Betamethasone Dipropionate EP Impurity J<br>Applications Betamethasone 9,11-Epoxide 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity F) is an impurity of Betamethasone (B327000), an antiinflammatory agent.<br>References Shou, M., et al.: J. Pharm. Biomed. Anal., 50, 356 (2009),<br></p>Formula:C28H36O7Color and Shape:White To Off-WhiteMolecular weight:484.584-Nitro-4’-aminodiphenyl Sulfone
CAS:<p>Applications An intermediate in the synthesis of the Daspone metabolite.<br></p>Formula:C12H10N2O4SColor and Shape:NeatMolecular weight:278.28Etomidate Hydrochloride
CAS:Controlled Product<p>Applications (cas# 53188-20-8) is a useful research chemical.<br></p>Formula:C14H17ClN2O2Color and Shape:NeatMolecular weight:280.75HBED Monohydrochloride Hydrate (>90%)
CAS:<p>Applications: N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic Acid Monohydrochloride Hydrate is a component for treating or preventing obesity and insulin resistance and mitrochondrial-associated disorders.N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic Acid Monohydrochloride Hydrate is also the monohydrochloride hydrate of HBED (H107503), which is an iron chelator useful in treating iron overload.<br>References Milburn, Michael, WO 2007008548, (2007)Bergeron, Raymond J., WO 9939706, (1999)<br></p>Formula:C20H24N2O6·HCl·x(H2O)Purity:>90%Color and Shape:NeatMolecular weight:424.88+x(18.02)Betamethasone 17-Butyrate
CAS:Controlled Product<p>Applications Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.<br></p>Formula:C26H35FO6Color and Shape:NeatMolecular weight:462.55Camphorquinone-10-sulfonic Acid Hydrate
CAS:Controlled Product<p>Applications A crystalline water-soluble reagent that is useful for specific, reversible modification of the guanidino groups of arginine residues. Suitable for use with small arginine-containing molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wallace, C.J.A., et al.: Biochem. J., 215, 651 (1983), Dailey, H.A., et al.: J. Biol. Chem., 261, 7902 (1986),<br></p>Formula:C10H14O5S·H2OColor and Shape:NeatMolecular weight:264.307α-Thiomethyl Spironolactone-d7 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Spironolactone.<br>References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),<br></p>Formula:C23H25D7O3SColor and Shape:NeatMolecular weight:395.61cis-Etoposide
CAS:<p>Applications cis-Etoposide is an anticancer agent that has half-life of 2 days at pH 7.4 and 37° resulting in the loss of 90% of the active drug within 1 week during in vitro incubations.<br>References Mader, R. M., et al.: Cancer Chemotherapy and Pharmacol., 27, 354 (1991)<br></p>Formula:C29H32O13Color and Shape:NeatMolecular weight:588.56
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