Pharmaceutical Standards
Subcategories of "Pharmaceutical Standards"
- APIs for research and impurities(276,268 products)
- Enzyme Activators and Inhibitors(2,829 products)
- Nitrosamines(2,621 products)
- Pharmaceutical and Veterinary Compounds and Metabolites(2,902 products)
- Toxicology(13,550 products)
Found 7951 products of "Pharmaceutical Standards"
α-Methylhydrocinnamic acid
CAS:Alpha-methylhydrocinnamic acid (AMHA) is a synthetic enantiomer of 2-phenylbutyric acid, which has been shown to inhibit the growth of k562 cells. It is also a substrate for fatty acid synthase and may play an important role in fatty acid metabolism. AMHA has been shown to inhibit the production of reactive oxygen species by phagocytic cells exposed to ionizing radiation, which may be due to its ability to scavenge hydroxyl radicals. The effect of AMHA on hematopoietic cells, including neutrophils and bone marrow cells, has not yet been determined.Formula:C10H12O2Purity:Min. 95%Color and Shape:White Clear LiquidMolecular weight:164.2 g/mol3-Amino-L-tyrosine dihydrochloride
CAS:Please enquire for more information about 3-Amino-L-tyrosine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C9H12N2O3•(HCl)2Purity:Min. 95%Molecular weight:269.12 g/molMertansine
CAS:N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine is a thiol-containing derivative of maytansine. Maytansine and its derivatives kill cells by interfering with the formation of microtubules, and causing the depolymerisation of already formed microtubules. Antibody conjugates of N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine and the murine monoclonal antibody TA. 1, using linkers containing either a disulfide bond or a thioether bond, have been synthesised. These antibody conjugates bind to the HER-2/new oncogene protein that is expressed on human breast tumor cells.Formula:C35H48ClN3O10SPurity:Min. 95%Color and Shape:White Off-White Yellow PowderMolecular weight:738.29 g/molFmoc-O-tert-butyl-D-threonine
CAS:Fmoc-O-tert-butyl-D-threonine is an ion pair that is synthesized using an asymmetric synthesis process. The molecule has been shown to have antiproliferative effects in animals and humans and can inhibit neutrophil function. This synthetic compound has a glycan (a carbohydrate) attached to the side chain, which may be important for its biological activity. Fmoc-O-tert-butyl-D-threonine was synthesized on a solid phase and functional groups were introduced as part of the synthesis process. This molecule also has an inhibitory effect on ulceration in animals.
Formula:C23H27NO5Purity:Min. 95%Color and Shape:PowderMolecular weight:397.46 g/mol6-Fluoro-2-(2'-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid
CAS:Brequinar sodium is a drug that belongs to the class of quinoline carboxylic acid derivatives. It has been shown to be effective in the treatment of infectious diseases and bowel disease. Brequinar sodium inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Brequinar also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formula:C23H15F2NO2Purity:Min. 97 Area-%Color and Shape:White/Off-White SolidMolecular weight:375.37 g/mol2-Bromo-5-chlorobenzoic acid methyl ester
CAS:2-Bromo-5-chlorobenzoic acid methyl ester is a chemical compound that is a component of the perborate oxidant. This chemical reacts with hydrogen peroxide to produce water, oxygen, and 2-bromo-5-chlorobenzoic acid. It can also be used in cyclisation reactions to synthesise heterocyclic compounds. The reaction mechanism for this process involves the formation of an unstable intermediate that spontaneously breaks down into two bromine atoms and one carbon atom. This process is catalyzed by metal ions such as copper, silver, and zinc. 2-Bromo-5-chlorobenzoic acid methyl ester has been used as an intermediate in the synthesis of homologues of ribonucleotide reductase.Formula:C8H6BrClO2Purity:Min. 95%Color and Shape:PowderMolecular weight:249.49 g/molN-D-Biotinyl-7-amino-4-methylcoumarin
CAS:N-D-Biotinyl-7-amino-4-methylcoumarin is a fluorescent substrate that is used to measure the activity of biotinidase, an enzyme that catalyzes the hydrolysis of biotin. It is detectable by measuring fluorescence with a spectrophotometer. Biotinidase deficiency can be diagnosed by measuring the activity of this enzyme in biological fluids. This assay has been shown to be useful for diagnosing patients with deficient biotinidase activity.Formula:C20H23N3O4SPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:401.48 g/mol4-(Hydroxymethyl)benzoic acid methyl ester
CAS:4-(Hydroxymethyl)benzoic acid methyl ester is a quinazolinone that has been used as an anticancer drug. It is synthesized by cross-coupling of 4-hydroxymethylbenzoic acid and methyl iodide with a cobaltic catalyst, followed by dehydrogenation. The synthesis can also be achieved using a molybdenum catalyst, leading to the same product. 4-(Hydroxymethyl)benzoic acid methyl ester is an efficient method for the synthesis of this compound and has shown anti-cancer activity in animal models. It inhibits serine proteases, including matrix metalloproteinases (MMPs) and cathepsin B, which are enzymes involved in cancer cell invasion and metastasis.Formula:C9H10O3Purity:Min. 95%Color and Shape:PowderMolecular weight:166.17 g/molMethyltestosterone
CAS:Controlled ProductMethyltestosterone is an androgenic steroid that is used for the treatment of male hypogonadism, delayed puberty, breast cancer, and as a component of hormone therapy for transgender women. It has been shown to increase the concentration of testosterone in the blood by binding to the androgen receptor. Methyltestosterone has been found to be effective in controlling symptoms of low testosterone in men with prostate cancer or undergoing chemotherapy. The optimum concentration of methyltestosterone varies from individual to individual, but it has been found that doses greater than 0.5 mg/day are not more effective at treating symptoms than lower doses. Methyltestosterone does not bind to human serum albumin, which makes it more bioavailable than other forms of testosterone. Methyltestosterone also binds to rat liver microsomes with significant interactions with other drugs metabolized by these enzymes (e.g., warfarin). The matrix effect has also been observed when methyltFormula:C20H30O2Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:302.45 g/mol2-Chloro-N-(2-nitrophenyl)acetamide
CAS:2-Chloro-N-(2-nitrophenyl)acetamide is an antimicrobial agent that is a ligand for thionyl chloride. It has efficient methods of production and can be used as a bioactive molecule in the synthesis of aminosulfonyl chlorides, amide chlorides, or transfer chlorides. This compound reacts with gram-negative bacteria by hydrolyzing chloride ions to produce nitrosyl chloride and releasing hydrogen gas. The reaction time and functional groups are determined by the parameters chosen for the reaction. 2-Chloro-N-(2-nitrophenyl)acetamide has luminescence properties that can be exploited to detect the presence of chloride ions at low concentrations.Formula:C8H7ClN2O3Purity:Min. 95%Molecular weight:214.61 g/molRetinamide
CAS:Retinamide is a synthetic retinoid that is used for the treatment of skin cancer. It has been shown to induce apoptosis by activation of the c-jun N-terminal kinase (JNK) and p38 pathways, as well as by suppression of signaling through the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Retinamide also inhibits proliferation of HL60 cells and induces mitochondrial membrane depolarization in colon carcinoma cells. This drug has been shown to be a potent inhibitor of squamous cell carcinoma growth in vitro and in vivo, especially when combined with other chemotherapeutic agents. Retinamide has also been found to be effective against group P2 carcinomas, which are characterized by mutations in the BRAF gene. Retinamide is metabolized by cytochrome P450 enzymes, leading to reactive metabolites that may cause toxic effects on cells. These metabolites can bind to DNA and cause strand breaksFormula:C20H29NOPurity:Min. 95%Color and Shape:PowderMolecular weight:299.45 g/molN-Acetyl-L-aspartyl-L-glutamic acid
CAS:N-Acetyl-L-aspartyl-L-glutamic acid is an amino acid that is used as a substrate in the biochemical assay for glutamate. It is also used to measure brain functions. NAAG is a low potency agonist of the NMDA receptor, which may contribute to neuronal death. NAAG is used as a model system to study bowel disease and eosinophil cationic protein. It has been shown to be effective in vitro against cancer cells and fungi. The structural analysis of NAAG has revealed that it contains an acidic group on its side chain, which can be detected with a pH indicator such as phenol red or bromocresol purple.Formula:C11H16N2O8Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:304.25 g/mol2-[(Ethylamino)methyl]-4-nitrophenol
CAS:Please enquire for more information about 2-[(Ethylamino)methyl]-4-nitrophenol including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C9H12N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:196.2 g/molSorbitan monolaurate
CAS:Sorbitan monolaurate is a natural compound that can be isolated from the seeds of the Cucurbitaceae family. It is used in sample preparation for biocompatible polymers, as well as for detergent compositions. Sorbitan monolaurate has been shown to act as an absorption enhancer, which may be due to its ability to form hydrogen bonds with other molecules and its capacity to interact with sodium citrate. Sorbitan monolaurate also has biological properties such as the inhibition of autoimmune diseases, malonic acid production, and bacterial growth.Formula:C18H34O6Purity:Min. 95%Color and Shape:Slightly Yellow Clear LiquidMolecular weight:346.46 g/molL-Aspartic acid b-methyl ester hydrochloride
CAS:L-Aspartic acid b-methyl ester hydrochloride is a high quality, versatile building block that can be used as a reaction component in the synthesis of complex compounds. L-Aspartic acid b-methyl ester hydrochloride is a useful scaffold for the preparation of novel fine chemicals and research chemicals with potential uses as pharmaceuticals, pesticides, and agricultural chemicals. It can also be used as an intermediate in the preparation of some natural products or industrial chemicals. L-Aspartic acid b-methyl ester hydrochloride has a CAS number of 16856-13-6.
Formula:C5H9NO4·HClColor and Shape:White PowderMolecular weight:183.59 g/mol5-Nitrovanillin
CAS:5-Nitrovanillin is a white crystalline solid with a molecular formula of C8H7NO2. It reacts with nucleophilic compounds, such as ammonia, in the presence of heat to produce a molecule containing an oxygen atom and two nitro groups. 5-Nitrovanillin has been found to undergo demethylation when heated in the presence of hydroxylamine. Reaction products include protocatechuic acid, nitromethane, and 5-nitrobenzoic acid. This compound can be identified by its characteristic nmr spectrum that includes a hydroxyl group and a hydrogen bond between the nitrogen atom and the hydroxyl group. The chemical ionization mass spectrometer can also be used to identify 5-nitrovanillin.
Formula:C8H7NO5Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:197.14 g/molGlucostrophanthidin
CAS:Glucostrophanthidin is a cardiac glycoside, which is derived from natural plant sources, specifically from species in the Apocynaceae family. This compound exerts its effects primarily through inhibition of the sodium-potassium ATPase enzyme, leading to an increase in intracellular sodium concentration. The downstream effect of this process involves an increase in intracellular calcium via the sodium-calcium exchange mechanism, ultimately enhancing the contractility of cardiac muscle fibers.
Formula:C29H42O11Purity:Min. 95%Molecular weight:566.64 g/mol4'-Methylacetophenone
CAS:4'-Methylacetophenone is a solvent that is used in the chemical industry, mainly for the production of trifluoroacetic acid. It has also been shown to be an effective antimicrobial agent, which is due to its ability to dissolve lipids and proteins. The mechanism of action of 4'-methylacetophenone is not fully understood, but it has been suggested that this compound reacts with fatty acids and pyrazole rings in the cell membrane and disrupts lipid bilayers. 4'-Methylacetophenone can be used as a reagent for solid phase microextraction in analytical chemistry. In addition, it reacts with acidic compounds (e.g., sulfuric acid) to produce insoluble salts and can be used as an analytical method for determining the concentration of these compounds.
Formula:C9H10OPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:134.18 g/molTropine
CAS:Tropine is a natural alkaloid that is derived from plants in the Solanaceae family including Atropa belladonna and Hyoscyamus niger. Tropine has been shown to have a number of physiological effects, including receptor binding, enzyme activities, and physiological effects. It has been used as an analytical method for determining sodium citrate, nitrogen atoms, and ester linkages. Tropine also has a ph optimum of 9-10 which means it should be dissolved in acidic solutions or diluted with a buffer solution before use. The reaction mechanism of tropine is not yet known, but it has been shown to contain fatty acid groups that are intramolecularly hydrogenated.Formula:C8H15NOPurity:Min. 95%Color and Shape:White PowderMolecular weight:141.21 g/mol3-Fluoro-DL-tyrosine
CAS:3-Fluoro-DL-tyrosine is a model system for the study of tyrosine transfer reactions. It is used to study the reaction mechanism and kinetics of tyrosine transfer from a donor molecule to an acceptor molecule. 3-Fluoro-DL-tyrosine reacts with trifluoroacetic acid to form 3,4-dihydroxybenzoic acid, which is a chemical analog of tyrosine. The hydroxyl group on this molecule can react with the proton on the amino acid side chain, forming a covalent bond that does not break down under normal conditions. This reaction is reversible and has been shown to be catalyzed by polymerase chain reactions (PCR).
Formula:C9H10FNO3Purity:Min. 95%Color and Shape:PowderMolecular weight:199.18 g/mol
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