Glycoscience

<p>2-Deoxy-2-fluoro-D-glucose 6-phosphate dipotassium is a fluorinated sugar that is used as a building block in the synthesis of complex carbohydrates. 2-Deoxy-2-fluoro-D-glucose 6-phosphate dipotassium can be modified to produce glycosylations, methylations, and click chemistry modifications. This product is sold as a custom synthesis and can be used for any desired modification.</p>

<p>(1S) -1- [(2S, 3S,4R) -N-Butyl-4-hydroxymethyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a synthetic monosaccharide that belongs to the group of complex carbohydrates. It has been modified by fluorination and methylation. This product can be synthesized according to customer specifications. The CAS number for this product is 97911-51-7. It is highly pure with a purity level of 98%. This product can be glycosylated or click modified according to customer specifications.</p>

<p>2'-Azidoethyl a-mannopyranoside is a synthetic monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. This product has been custom synthesized for your specific needs. It is an off-white powder with purity greater than 99%. The methylation of this compound can be achieved by reacting it with sodium methoxide in methanol, followed by hydrolysis with sodium hydroxide. The azido group can also be converted to an acetyl group by reaction with acetic anhydride in pyridine.</p>

<p>Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd</p>

<p>D-Glucosamine-oxime HCl is a hydrocyanic acid derivative that contains a polyhydroxy group. It can exist as two isomers, D-glucosamine and D-glucosamine-oxime. These isomers are distinguished by the presence or absence of acetyl groups on the nitrogen atoms. D-Glucosamine-oxime HCl functions as a divalent metal ion chelator and sequestering agent that has been shown to be useful in the treatment of lead poisoning. It also has been used in the synthesis of hydrocyanic acid, which is an important chemical for organic synthesis.END&gt;</p>

<p>Lactose is the principal sugar in human and most other mammalian milks, ( 4-O-(β-d-galactopyranosyl)-d-glucopyranose) (Collins, 2006). Lactose undergoes mutarotation; it is a reducing sugar and is significantly less soluble in water than sucrose. Lactose is much less sweet than sucrose (at ~1% about 0.15 (sucrose=1). The enzyme lactase (β-galactosidase), which is present in the small intestine, catalyzes hydrolysis of lactose to form glucose and galactose. Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. Lactose also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods (Linko, 1982).</p>

<p>L-Arabinose diethyldithioacetal is a potassium carbonate derivative of L-arabinose that reacts with sulfur to form 1,2-dithioketals. These dithioketals are used as glycosyl donors in the synthesis of L-fucitol and d-xylose. This reaction is catalyzed by acetobacter, which converts L-arabinose and carbon dioxide into acetaldehyde and acetic acid. The reaction mechanism for this transformation includes an epimerization of the hydroxyl group on the C5 position of L-arabinose to a hydroxyl group on C6, followed by glycosidation with sulfuric acid. The glycosidic bond formed between the hydroxyl group on C6 and the carbonyl group at C1 (in this case, from L-arabinose) is called an acetal linkage. In addition to being antithrombotic</p>

<p>11-Dehydroxygrevilloside B is a natural glycoside compound, which is primarily isolated from the plant genus Grevillea. This genus is known for its rich diversity of secondary metabolites with various biological activities. The mode of action of 11-Dehydroxygrevilloside B involves interactions with specific molecular targets, potentially influencing biochemical pathways associated with inflammation, oxidative stress, or other cellular processes. Its exact mechanism is still under research, aiming to unravel its potential therapeutic or protective effects. Applications of 11-Dehydroxygrevilloside B are mainly within the realm of biochemical and pharmacological research, where it serves as a subject for in vitro or in vivo experiments to explore its efficacy and safety profile. Its study contributes to understanding how plant-derived compounds can be harnessed for medicinal purposes and augments the exploration of novel drug candidates from natural sources.</p>

<p>Benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-b-D-glucopyranoside is a surfactant that is used in the measurement of polymers. It is soluble in water and has a low concentration. This surfactant can be used as a copolymer with terephthalate to form polyurethane foam. Benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene b -D -glucopyranoside also has high concentrations for sedimentation and sulfonate properties.</p>

<p>DL-Apiose, also known as D-apiose, is a carbohydrate that is found in the bark of the tree Dolichandrone. It can be synthesized from verbascoside, a product of the thermally and irradiation degradation of verbascoside. This compound has been shown to have anti-inflammatory properties. DL-Apiose has two stereoisomers: alpha and beta. Alpha-DL-apiose is an intramolecular hydrogen bond donor while beta-DL-apiose is an intramolecular hydrogen bond acceptor. The alpha form can be converted to the beta form by ring opening. The alpha form of this compound has a hydroxyl group at carbon 2 and the beta form does not have this group. The alpha form of DL-apiose is more soluble than the beta form and may be more biologically active than its counterpart.</p>

<p>A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus vesiculotus, Durvillea (illustrated), Alaria and Cladosiphon) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta.<br>The fucose content of this fucan is approximately 27.9% and it also contains galactose (approx. 6.2%), uronic acid (approx. 22.4%) and sulfate (approx. 21.4%).<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Ethyl 2,3,4,6-tetra-O-acetyl-b-D-thiogalactopyranoside is a natural sugar that is used in the food industry as a flavoring agent.</p>

<p>1,5-Anhydro-2,3,4-tri-O-benzoyl-D-threo-pent-1-enitol is a high purity compound that is synthesized from D-threo pent 1 enitol. It is a sugar that belongs to the category of complex carbohydrates. This product can be custom synthesized and modified according to customer requirements.</p>

<p>5-Deoxy-5-dimethylamino-1,2-O-isopropylidene-a-D-xylofuranose is a fluorinated monosaccharide that is used as a synthetic building block for the synthesis of oligosaccharides and polysaccharides. It is used in glycosylation reactions to introduce fluoride at the anomeric carbon. 5-Deoxy-5-dimethylamino-1,2-O-isopropylidene is also used in click modification reactions to modify methyl groups. The CAS number for 5DDAIWF is 14514743. 9. This product has high purity with a purity of greater than 99%.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>D-Galactosamine is a glycosaminoglycan (GAG) that is found in the mammalian cell. N-Thioglycolyl-D-galactosamine is a synthetic analog of D-galactosamine that was developed to study the biosynthesis of GAGs and glycoconjugates in cells. This molecule can be activated by hematopoietic cells, which leads to an increase in o-glycosylation and galnac synthesis.</p>

<p>1,2,3,4-Tetra-O-benzyl-6-O-triisopropylsilyl-b-D-galactopyranose is a synthetic compound that is used as an intermediate in the synthesis of oligosaccharides and polysaccharides. It is a methylated derivative of galactose. The silyl protecting group on the benzyl side chain can be removed by hydrolysis with acid to give 1,2,3,4-tetra-O-(hydroxymethyl)galactopyranose. This product can be converted to 1-(2,3,4,-trihydroxypropoxy)-2-(1,1'-biphenyl)-6H-thiopyran using click chemistry. The hydroxymethyl group on position 4 can be fluorinated at the 4' position to give 1-(2',3',4'-trihydroxyprop</p>

<p>Ulvan is a complex carbohydrate that has been modified with methylation, fluorination, and click chemistry. Ulvan can be used in the synthesis of oligosaccharides and saccharides. It is also an important glycosylation product. Ulvan has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>Eugenol-glucuronide is an indirubin analog that has been found to have potent anticancer properties. It acts as a kinase inhibitor, blocking the activity of proteins that are involved in cancer cell growth and proliferation. Eugenol-glucuronide induces apoptosis, a process by which damaged or abnormal cells are eliminated from the body. It has been shown to be effective against human and Chinese hamster ovary tumor cells in vitro. This medicinal compound is excreted in urine and has potential for use in cancer treatment as an inhibitor of tumor growth.</p>

<p>Cellulose derivative, food thickener and emulsifier, bulk forming laxative</p>