Glycoscience

<p>4,7,8,9-Tetra-O-acetyl-N-acetyl-D-neuraminic acid methyl ester is a modified form of sialic acid. This compound is a glycosylation product that has been modified with methyl groups and fluorine atoms. The fluorination of the molecule increases its stability and prevents it from being hydrolyzed by enzymes such as β-galactosidase. 4,7,8,9-Tetra-O-acetyl-N-acetyl-D-neuraminic acid methyl ester is often used in the synthesis of polysaccharides and oligosaccharides for medical purposes. This compound can be custom synthesized for research purposes or to meet special requirements.</p>

<p>Losartan N1-glucuronide is a glucuronidated metabolite of losartan that is produced naturally in the human body. It is converted from losartan by the enzyme UDP-glucuronosyltransferase, which is found in humans and other animals. The rate of glucuronidation varies between individuals and is determined by genetic factors. Losartan N1-glucuronide has shown to be an effective inhibitor of angiotensin II, with an IC50 value of 1.4 μM. This inhibition can be reversed by dobutamine or recombinant human UGT2B7 enzyme, which are both competitive inhibitors of the enzyme UGT2B7. Magnetic resonance spectroscopy has been used to study the kinetic properties of this inhibitor and its effect on dobutamine-induced changes in cardiac function.</p>

<p>D-Glucose 2-phosphate (D-G6P) is a glycolysis intermediate that is generated by the enzyme phosphoglucose isomerase. It is necessary for the synthesis of glycogen and starch, as well as for the formation of glucose 6-phosphate in glycolysis. D-G6P has been shown to be an important substrate for enzymes involved in phosphate transfer. D-G6P also plays a role in mitochondrial function, as it can be converted to ATP by the enzyme pyruvate kinase. D-G6P has been shown to alter physiological effects in wild type strains of yeast and plants, as well as having disease activity against human serum.</p>

<p>Gal[2346Ac]b(1-3)GlcN3[46Bzd]-b-MP is a custom synthesis that has been modified with fluorination, methylation, and modification. The product contains a monosaccharide, oligosaccharide, saccharides, and complex carbohydrates.</p>

<p>Tween 40 is a non-ionic surfactant that has been used in the reaction mechanism of lipolytic enzymes. It has been shown to have metabolic effects on fatty acids, with an increase in the rate at which they are metabolized. Tween 40 is also a component of particle suspensions and may be used as a medium for chemiluminescence reactions. Sodium salts such as sodium benzoate or sodium chloride may be added to the solution to produce light emission. Tween 40 has also been shown to provide linear calibration curves for quantitative measurement of glutamate levels in biological fluids by fluorescence photometry. The use of Tween 40 can prevent eye disorders, such as dry eye syndrome, due to its lubricating properties. Tween 40 is synthesized by the esterification of sorbitol and oleic acid with ethylene oxide.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>Ethyl-3,6-di-O-benzoyl-2-trifluoromethanesulfonyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-b-D-mannopyranoside is a synthetic modified oligosaccharide that has been fluorinated. It is a complex carbohydrate that has a CAS number of 1008750-65-9. The modification of the monosaccharides in this product are methylation and click modification.</p>

<p>D-(+)-Melezitose dihydrate is a potent inhibitor of cancer cell growth. It has been shown to inhibit the proliferation of Chinese hamster ovary cells and human bladder cancer cells in vitro. D-(+)-Melezitose dihydrate is also found in urine samples from cancer patients, suggesting that it may be a potential biomarker for cancer diagnosis. This compound has been identified as an analog of indirubin, which is known to have anti-tumor properties. D-(+)-Melezitose dihydrate has been shown to induce apoptosis in cancer cells by inhibiting protein kinases, including the kinase inhibitors and tumor suppressor proteins. Additionally, this compound has demonstrated anticancer activity against a variety of tumors, making it a promising candidate for future cancer therapies.</p>

<p>1,6-Anhydro-3-O-benzyl-b-L-idopyranose is an oligosaccharide in which the aldehyde group of the original sugar has been modified. It is a complex carbohydrate that is synthesized by the fluorination of glucose with 1,6-dichlorohexane and benzyl bromide. The product is purified by crystallization and recrystallization to obtain a high purity. It is a monosaccharide sugar that can be used as a starting material for modification or synthesis of other carbohydrates.</p>

<p>6-O-tert-Butyldiphenylsilyl-D-glucal is a methylated sugar that can be used for glycosylation. It is an important building block for the synthesis of oligosaccharides and polysaccharides. The compound is readily available in high purity, which makes it suitable for synthesis of complex carbohydrates. In addition to its use as a synthetic reagent, 6-O-tert-Butyldiphenylsilyl-D-glucal can be used as a fluorinating agent. This product is listed as CAS No. 87316-22-1 in the Chemical Abstract Service (CAS) registry.</p>

<p>Phenyl 2,3,4-tri-O-acetyl-6-O-benzyl-b-D-thiogalactopyranoside is a complex carbohydrate with an Oligosaccharide and Polysaccharide backbone. This compound can be modified with methylation to produce a saccharide with a specific structure. Phenyl 2,3,4-tri-O-acetyl-6-O-benzylb -D -thiogalactopyranoside is a high purity, synthetic glycosylated material. It has been fluorinated to form the corresponding fluorinated product.</p>

<p>GalNAca1-3Galb1-4GlcNAc</p>

<p>2-O-(3,4,6-Tri-O-acetyl-2-deoxy-2-N-phthalimido-b-D-glucopyranosyl)-3-O-benzyl-4,6-benzylidene -D -mannopyranose is a custom synthesis. It is a complex carbohydrate that has been modified with methylation and glycosylation. The saccharide in this compound is an oligosaccharide that has undergone fluorination and click chemistry. This product is of high purity and offers a range of useful applications.</p>

<p>T-Antigen-APE-HSA is a custom synthesis, modification, and fluorination of T-antigen. This product has been synthesized by methylation and monosaccharide synthesis. It also contains a saccharide that is glycosylated or modified with polysaccharides. This product is made up of complex carbohydrates that are composed of oligosaccharides and sugar chains.</p>

<p>α-Fructoselysine dihydrochloride is a custom synthesis of a complex carbohydrate with an Oligosaccharide and Polysaccharide. It has been modified by Methylation and Glycosylation. α-Fructoselysine dihydrochloride has a CAS number of 96192-34-6, which is used for Click modification. This product is pure and high in purity, as well as being Fluorinated and Synthetic.</p>

<p>Ulvans are structural polysaccharides present in the cell walls of green algae such as Ulva armoricana, Ulva rotondata, Ulva rigida, Ulva lacterca and Ulva pertusa. They are highly sulphated and contain rhamnose 3-sulphate, xylose, xylose 2-sulphate, glucuronic acid and iduronic acid residues. Ulvan has several potentially valuable functionalities such as gel formation for agricultural and food applications and possible anticoagulant, antioxidant, antihyperlipidemic and antitumoral activities for pharmaceutical applications.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>3-Chloro-3-deoxy-1,2:5,6-di-O-isopropylidene-a-D-glucofuranose is a monosaccharide that is used as an intermediate in the synthesis of complex carbohydrates. It is synthesized by the Click reaction of 3,4,5,6,-tetrachlorohexanoic acid with 2,3:5,6-diisopropylidene glucose. This product has been modified by fluorination and saccharide modification. Custom synthesis can be performed on this product to produce any desired oligosaccharides or polysaccharides. The purity of this product is &gt;98%.</p>

<p>Methyl 2-deoxy-a-D-ribofuranoside is an atypical nucleoside, which is a component of the thiourea cofactors. It can be synthesized from chloroacetic acid and hydantoin, which are used as starting materials for the production of this compound. The methyl group in this compound is obtained from the methylation of glucose. Methyl 2-deoxy-a-D-ribofuranoside can be identified by its chromatographic properties, such as dimethylformamide (DMF) and chloride. It also contains anomeric substituents that are necessary for nucleosidation reactions. This nucleoside has been shown to have antiinflammatory activity against carrageenan in mice and rats.</p>

<p>2-Pyridyl-2,3,4,6-tetra-O-acetyl-1-deoxy-a-D-manno-1Cpyranoside is a glycosylated pyranoside that can be used as a building block to synthesize complex carbohydrate. It has been modified with fluorination and acetylation. The purity of this compound is greater than 98% and it is available for custom synthesis.</p>

<p>Please enquire for more information about Methyl 2-deoxy-4,6-o-(phenylmethylene)-α-D-ribo-hexopyranoside benzoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>