Glycoscience

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. A number of publications have suggested that agaroheptaose has properties that include: anti-microbial, antiviral, prebiotic, anti-tumoral, immunomodulatory, anti-inflammatory, glucosidase inhibitory, and hepatoprotective properties.</p>

<p>Pectin is a highly complex polysaccharide matrix that is found in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms, including potato. A key fragment of this complex is rhamnogalacturonan I, containing a backbone of the repeating disaccharide  [-4)-α-D-GalpA-(1,2)-α-L-Rhap-(1,]. Several applications for RG1 have been described including drug targeting to the colon via the oral administration route for local treatment of e.g. inflammatory bowel disease and colon cancer.  This has several advantages such as needle-free administration and low infection risk. In the gastro-intestinal tract RG-I is only degraded by the action of the colonic microflora. High purity rhamnogalacturonan I is also used in research, biochemical enzyme assays and in vitro diagnostic analysis.</p>

<p>1-Bromo-2,3,4-tri-O-benzoyl-a-D-glucuronide methyl ester is a custom synthesis. It is a high purity product with a custom synthesis. The CAS No. for this compound is 103674-69-7. This product undergoes Click modification and has high purity. The sugar in this compound is an oligosaccharide with glycosylation.</p>

<p>Difucosyl-para-lacto-N-hexaose-APD-HSA is a complex carbohydrate that is a custom synthesis. It has been modified by the addition of difucosyl groups to the para position of lactose and by the attachment of an APD moiety to the N-acetyl group of hexitol. The molecular weight is approximately 1,000 Da. This product is used in glycosylation reactions, such as polysaccharide synthesis, and in fluorination reactions. Difucosyl-para-lacto-N-hexaose-APD-HSA can be found under CAS No. 366511-00-7 and is soluble in water and DMSO.</p>

<p>1,4,6-Tri-O-acetyl-2,3-O-carbonyl-a-D-mannopyranose is a synthetic carbohydrate that can be modified with fluorine to produce its active form. This molecule has been shown to inhibit bacterial growth by inhibiting cell wall synthesis and protein synthesis. 1,4,6-Tri-O-acetyl-2,3-O-carbonyl-a-D-mannopyranose has been shown to have high purity and custom synthesis, as well as methylation and glycosylation.</p>

<p>Methyl 3-acetamido-4-O-benzoyl-6-bromo-2,3,6-trideoxy--aDribohexopyranoside is a Custom synthesis that is classified as an Oligosaccharide. It has a molecular weight of 576.07 and a purity of &gt;99%. The chemical formula for this compound is C22H30BrNO8. Methyl 3-acetamido-4-O-benzoyl-6-bromo-2,3,6--trideoxy--aDribohexopyranoside is used in the modification of saccharides with the purpose of synthesizing polysaccharides. This compound has been shown to be effective for the synthesis of glycosylations and methylations.<br>Methyl 3 acetamido 4 O benzoyl 6 bromo 2,3,6 trideoxy - a D rib</p>

<p>Gala1-3(Fuca1-2)Galb1-4GlcNAcb1-3Gal (B antigen pentasaccharide Type II)</p>

<p>Detergent with CMC of ~ 39mM</p>

<p>4-Epi-daunosamine is a glycopeptide antibiotic that is used to treat infections caused by Gram-positive bacteria. It binds to the cell wall of these bacteria and inhibits the synthesis of new cell walls. This causes the cells to burst and die, which leads to bacterial death. 4-Epi-daunosamine has been shown to be effective against animal pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, and Clostridium perfringens. 4-Epi-daunosamine also has a low level of toxicity in humans, but can cause adverse effects such as nausea and vomiting if taken in large doses.</p>

<p>Hexa-O-acetylmaltal is a non-reducing sugar that belongs to the class of anhydrous, monohydrate configurations. It is a synthetic substrate that is used in the synthesis of pyridine analogues. Hexa-O-acetylmaltal can be crystallized in chloroform and activated with heat or acid. The anomeric configuration has been determined by X-ray diffraction analysis and its configuration was shown to be anomeric by chemical degradation. Hexa-O-acetylmaltal can also form heptaacetate, which is a disaccharide.</p>

<p>Glucobrassicin potassium is a glucosinolate-derived compound, which is a naturally occurring metabolite found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. These compounds are biosynthesized in plant cells and are integral to the plant's defense mechanism against pests and diseases.</p>

<p>1,2,3,4,6-Penta-O-acetyl-a-D-talopyranose is a fluorinated monosaccharide that belongs to the class of synthetic oligosaccharides. It can be used in glycosylation and polysaccharide synthesis. The chemical structure of this compound has been modified by methylation and click chemistry. 1,2,3,4,6-Penta-O-acetyl-a-D-talopyranose is available in high purity and custom synthesis.</p>

<p>Methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thiophenyl-D-glycero-a-D-galacto-2--nonulopyranosylonate is a synthetic monosaccharide with a high purity. It is an oligosaccharide consisting of one methylated acetamido group and four acetyl groups on the nonulopyranosyl ring. Methyl 5 Acetamido 4,7,8,9 Tetra O Acetyl 3 Dideoxy 2 Thiophenyl D Glycero A D Galacto 2 Nonulopyranosylonate is used in glycosylation reactions in the synthesis of complex carbohydrates. The compound has been modified by fluorination to increase its stability in harsh conditions.</p>

<p>Allyl 4,6-O-benzylidene-b-L-glucopyranoside is a carbohydrate that is synthesized from allyl alcohol and glucose. It is a complex carbohydrate made up of two different saccharides. This product can be custom synthesized to meet your needs. Allyl 4,6-O-benzylidene-b-L-glucopyranoside has been modified by fluorination, methylation and glycosylation. It has the CAS number 133394-02-0 and can be synthesized at high purity levels.</p>

<p>4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is a synthetic, water soluble, non-digestible oligosaccharide. It has regulatory effects on the utilisation of glucose and lacto-n-neotetraose by various cells in vitro. This compound also inhibits the development of intestinal pathogens in humans and elucidates their sequence specificity. 4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is used to study the role of this molecule in infant nutrition.</p>

<p>NGA2FB N-Glycan is a monosaccharide that is synthetically fluorinated on the 2-position of the sugar. It is an oligosaccharide that contains a complex carbohydrate, which is a glycosylation of a polysaccharide with a click modification at the methyl group on the sugar. This product can be custom synthesized to order and offers high purity.</p>

<p>Mannitol is a sugar alcohol occurring widely in plants and they are exudates, for example, in olive and plane trees (Collins, 2006). It is produced commercially by the catalytic hydrogenation of fructose (Zelin, 2019). Mannitol is used extensively in food and pharmaceutical industries because of its unique functional properties. It is about 50% as sweet as sucrose and has a desirable cooling effect often used to mask bitter tastes. Mannitol is non-cariogenic and has a low caloric content. Mannitol is an osmotic diuretic that is metabolically inert in humans and is used for: the promotion of diuresis before irreversible renal failure becomes established, the promotion of urinary excretion of toxic substances, as an Antiglaucoma agent, and as a renal function diagnostic aid (O’Neil, 2013). Additonally, in 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients (McKenna, 2020).</p>

<p>4-O-Acetyl-3,6-di-O-triisopropylsilyl-D-galactal is a modified sugar that can be used as a chiral building block in the synthesis of complex carbohydrates. This product is available for custom synthesis.</p>

<p>2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl ethylxanthate is a synthetic carbohydrate that has been modified with acetyl groups. This modification is used to produce a carbohydrate that is more resistant to hydrolysis by enzymes. 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl ethylxanthate is one of many glycosides that have been modified with acetyl groups and fluorinated. This modification can be used for the synthesis of high purity carbohydrates.</p>

<p>2-Chloro-2-deoxy-1,3,4,6-tetra-acetyl-D-glucopyranose is a custom synthesis of a monosaccharide that contains a fluorine atom. It is synthesized by modifying the 2 position with chlorination and then methylation. This monosaccharide can be used for glycosylation and saccharide synthesis.</p>