Glycoscience

Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).

L-Daunosamine-b-methylglycoside hydrochloride is a high purity, custom synthesis of an oligosaccharide. This product is synthesized from D-mannose and L-daunosamine. The synthetic process begins with the click modification of the carbohydrate to introduce a methyl group onto the sugar. The resulting product is then glycosylated, fluorinated, and methylated to create the final product. L-Daunosamine-b-methylglycoside hydrochloride has been shown to act as a competitive inhibitor of bacterial dna gyrase, which helps maintain the integrity of bacterial DNA by preventing supercoiling. L-Daunosamine-b-methylglycoside hydrochloride has also been shown to inhibit protein synthesis in bacteria by binding to ribosomes, which are responsible for translating mRNA into proteins.

L-Idaric acid is a novel anti-inflammatory agent that is a derivative of the endogenous compound d-glucuronic acid. It has been shown to have anti-inflammatory effects in animal studies as well as in human cell cultures and it has been shown to be safe for use in humans. L-Idaric acid inhibits the production of inflammatory mediators, such as prostaglandins, leukotrienes, and cytokines. L-Idaric acid also inhibits the activity of β-glucuronidase, which may be responsible for its ability to prevent the degradation of glucuronic acid derivatives.

1,3,4,6-Tetra-O-acetyl-N-(4-methoxybenzylidene)-b-D-glucosamine is a high purity custom synthesis sugar that has been fluorinated and glycosylated. It is synthesized from the methylation of 4-(1,3,4,6-tetra-O-acetyl)-N-(4-hydroxybenzylidene)-b-D-glucosamine and can be used for the modification of saccharides or oligosaccharides. This compound has CAS No. 7597-81-1 and is known as a carbohydrate.

Olmesartan acid O-b-D-glucuronide is a synthetic, high purity, and custom synthesis oligosaccharide. It can be fluorinated in the presence of a base to give a fluorinated compound with the following CAS number: 369395-57-3. Olmesartan acid O-b-D-glucuronide is an oligosaccharide that has been modified by click chemistry. This modification results in a polysaccharide that contains saccharides connected through ether linkages. The saccharides are made up of monosaccharides and disaccharides, which are all sugars.

Dodecyl a-D-glucopyranoside is a fatty acid that is found in the form of dodecyl glucoside. It has been shown to be effective against infectious diseases, such as pneumococcal infections and influenza. Dodecyl a-D-glucopyranoside inhibits bacterial growth by preventing the synthesis of lipopolysaccharides, which are important for the cell wall structure of Gram-negative bacteria. Dodecyl a-D-glucopyranoside also inhibits monoclonal antibody production, which may be due to its ability to inhibit protein synthesis. In addition, dodecyl a-D-glucopyranoside is used as an adjuvant in vaccines against autoimmune diseases.

3'3-a-L-Arabinofuranosyl-xylotetraose is a custom synthesis of an oligosaccharide. It is a polysaccharide that is modified by methylation, glycosylation and carbamoylation. This carbohydrate has been fluorinated at the 3'3 position. The monosaccharide composition of this molecule is erythrose, arabinose and xylose.

Ouabain is a potent inhibitor of the Na+/K+-ATPase pump in cardiac and skeletal muscles. It has been shown to inhibit signal pathways that are involved in the regulation of cellular membrane potentials, such as the michaelis–menten kinetics. Ouabain has also been found to be effective against syncytial virus infection. Ouabain inhibits viral replication by inhibiting cellular protein synthesis and reducing cell number due to its cytotoxic effects on myocardial cells. Ouabain has also been found to inhibit neuronal death induced by α1-adrenergic receptor agonists, such as p2y receptors.

D-[1-13C]Xylose is a carbon source that is used to study the metabolism of glycolytic carbon in cells. It has been labeled with 13C and can be used as a tracer for the study of the distribution of metabolites, including glucuronic acid, mannose, and xylose. This can be done by nuclear magnetic resonance (NMR) spectroscopy or by using a magnetic resonance spectroscopy technique. The use of D-[1-13C]xylose has been shown to be an effective way to label cryptococcus neoformans cells in order to understand their metabolism.

D-[1-13C]Galacturonic acid potassium salt is a sugar that is synthesized by the reaction of galactose with carbon dioxide. This sugar has been custom synthesized and is used in glycosylation reactions. Other modifications to this sugar include methylation and click modification, which can be done to make the sugar more reactive. D-[1-13C]Galacturonic acid potassium salt is a high purity product with a CAS number.

3-Azido-5-O-benzoyl-3-deoxy-1,2-O-isopropylidene a D-ribofuranose (3ABI) is a synthetic monosaccharide that can be synthesized via a custom synthesis. 3ABI is an oligosaccharide that has the ability to modify glycosylation and polysaccharide synthesis. The fluorination of this sugar provides it with high purity and stability. 3ABI has been shown to have a CAS number of 44793-23-2.

The maltose solution we offer is a 20% solution in water and of high purity and can be customized to meet your needs.

Cis-Zeatin-9-glucoside is a plant hormone known as a cytokinin, which is primarily synthesized in plants such as Zea mays (corn) and other monocots. Cytokinins play a critical role in regulating plant growth and development by promoting cell division, influencing nutrient allocation, and delaying leaf senescence. The mode of action of cis-Zeatin-9-glucoside involves its role as a signaling molecule that interacts with specific receptors in plant cells, thereby triggering a cascade of gene expression changes that modulate physiological processes.

Glcnacβ(1-2)man-α-ethylazide is a modified oligosaccharide that has been synthesized from the sugar GlcNAcβ(1-2)mannose. It is a complex carbohydrate with a high purity, which can be used as a custom synthesis. The synthesis of this product involves fluorination and saccharide methylation. The CAS number for this product is 1858224-15-3.

GM2-Oligosaccharide-spacer-NH2 ammonium is a complex carbohydrate with an oligosaccharide spacer and a hydrophobic NH2 group. The product is custom synthesized to your specifications and is available in high purity. It can be modified with fluorination or click chemistry. GM2-Oligosaccharide-spacer-NH2 ammonium is used in the synthesis of polysaccharides, saccharides, and carbohydrates. Some of its applications include modifying proteins, monosaccharides, and sugars.

Rhamnolipids are a class of biosurfactants which contain rhamnose as the sugar moiety linked to β-hydroxylated fatty acid chains. Rhamnolipids can be widely applied in many industries including; petroleum, food, agriculture and bioremediation etc.

Octyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a lyotropic liquid that is flammable. It can be used to prepare potassium hydride, which is an organometallic. Potassium hydride reacts with organic acids and atorvastatin to produce argon gas. This reaction can be done in the presence of chlorine gas instead of air. Preparative methods for octyl 2-acetamido-2-deoxy-b-D-glucopyranoside include heating it in a vacuum or under argon gas and then reacting it with potassium tetrachlorocobaltate in water or ethanol solution.

4-Aminophlorizin is a chemical compound that inhibits the uptake of azide by red blood cells. It has been shown to be effective against intestinal parasites and trophozoites. 4-Aminophlorizin is a potent inhibitor of the membrane system, which may be due to its interaction with the semenza, or membrane protein.