Glycoscience

<p>i-carrageenan-derived decasaccharide alcohol decasulfate +(3-6 anhydrogalactose)</p>

<p>2,7-Anhydro-D-sedoheptulose-2,3,4,5,6,7-13C6 is a custom synthesis of a complex carbohydrate. It is an oligosaccharide that is modified with methylation and glycosylation. This compound has been synthesized by Click modification and fluorination. 2,7-Anhydro-D-sedoheptulose-2,3,4,5,6,7-13C6 is water soluble and has a high purity. It is used as a research tool in the field of saccharides and carbohydrates.</p>

<p>Dextran is α-(1,6)-linked α-D-glucan produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose. The main use for native dextran is as a blood plasma extender in blood transfusions. A complex of iron with dextran, known as iron dextran, is used as a source of iron to baby piglets which are often anaemic at birth.</p>

<p>2-Azido-2-deoxy-3,4-(R)-benzylidene-D-arabino-1.5-lactone is a fluorinated sugar that can be used for glycosylation reactions. It is a custom synthesis and its CAS number is 54856-82-9. This sugar has been modified with methyl groups to increase its stability in the presence of water. The sugar is highly pure and has a purity of 98%.</p>

<p>1-Deoxy-L-sorbito is a Glycosylation, complex carbohydrate, Methylation, Click modification, Polysaccharide, Fluorination, saccharide, Modification, sugar, Oligosaccharide. It is a custom synthesis and it is available in high purity.</p>

<p>2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-b-D-galactopyranose is fully acetylated D-galactosamine (C4 epimer of D-glucosamine). 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-b-D-galactopyranose is used in the synthesis of α- and β-linked acetamido pyranosides, which have anti-inflammatory properties as inhibitors of TLR4.</p>

<p>k-carrageenan derived tetrasaccharide alcohol disulfate+(3-6 anhydrogalactose)</p>

<p>Disialyllacto-N-tetraose is a medicinal compound that has shown promising anticancer properties. It is an analog of a human urinary glycoprotein and has been found to induce apoptosis in cancer cells. Disialyllacto-N-tetraose acts as a tumor inhibitor by blocking the activity of certain protein kinases, which are enzymes that play a role in cell growth and division. This compound has been studied extensively in Chinese medicine and has shown potential as an effective anticancer agent. Its unique structure and mechanism of action make it a promising candidate for further research into cancer treatment.</p>

<p>2,3,5,6-Tetra-O-acetyl-D-galactono-1,4-lactone is a morpholidate that can be synthesized from l-fucose and phosphates. This chemical has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis. The compound also inhibits the production of diphosphorylated guanosine (GDP) from guanosine monophosphate (GMP), which may be important in the regulation of cellular growth. 2,3,5,6-Tetra-O-acetyl-D-galactono-1,4-lactone has also been shown to inhibit the conversion of GMP into GTP by binding to the enzyme GMP synthase.</p>

<p>Maltoeicosaose is a synthetic oligosaccharide that is synthesized by the glycosylation of maltose with a sugar. Maltoeicosaose can be custom synthesized for different applications, such as complex carbohydrate, glycosylation, polysaccharide, and click modification.</p>

<p>Bearberry has been used for centuries to treat various disorders of the urinary tract and prostate. The active ingredient in bearberry is a flavonol glycoside called arbutin, which is converted to hydroquinone during metabolism. As an antioxidant, hydroquinone inhibits the oxidation of LDL cholesterol and may reduce the risk of atherosclerosis. Hydroquinone has also been shown to have anti-inflammatory properties in rat liver microsomes and tissue culture, inhibiting prostaglandin synthesis by blocking cyclooxygenase activity. In vitro, bearberry extracts have been shown to inhibit bacterial growth on agar plates with pH levels from 4-7 and at concentrations between 0.1-1%. It was found that bearberry extracts were most effective against Pseudomonas aeruginosa strains, with MIC values ranging from 2-4 mg/mL. Bearberry extract was observed to be more effective than ampicillin against these strains in a chromatographic assay.</p>

<p>7, 8, 9, 10-Tetradeoxy-1,2:5,6-O-isopropylidene-L-glycero-a-D-gluco--decofuranose is a custom synthesis of a monosaccharide that can be modified with fluorination or methylation. It is synthesized by the click modification of an oligosaccharide and saccharide. This compound has CAS No. 156637-10-3 and is classified as a polysaccharide. 7,8,9,10 Tetradeoxy 1,2:5,6 O Isopropylidene L Glycero A D Glucodecofuranose is a carbohydrate that has glycosylation and sugar modifications.</p>

<p>2-O-Benzoyl-3,4-O-benzylidene-D-ribopyranose is a fluorinated monosaccharide that has been synthesized and modified. The molecular formula is C11H14FO7 and the molecular weight is 307.27. It can be used in glycosylation reactions to produce oligosaccharides or polysaccharides. 2-O-Benzoyl-3,4-O-benzylidene-D-ribopyranose can also be methylated to produce methylated carbohydrates. This product is of high purity and has a CAS number.</p>

<p>2-Amino-2-deoxy-3,4-O-isopropylidene-L-idonic acid methyl ester is a glycosylation agent that has been used in the synthesis of complex carbohydrates. It has also been used as a monosaccharide to produce Oligosaccharides and polysaccharides. The compound is fluorinated and saccharified with acetic anhydride and sulfuric acid to produce 2-Amino-2,3,4,5,6,-pentafluorohexylidene-(D) -L -idonic acid methyl ester. This product is custom synthesized by our company.</p>

<p>4-O-Acetyl-N-acetyl-neuraminic acid is a derivative of sialic acid, which is an important component of the human cell membrane. It has been found to have inhibitory properties against influenza virus and other viruses. 4-O-Acetyl-N-acetyl-neuraminic acid inhibits viral activity by irreversible inhibition of the α subunit on the surface glycoprotein, preventing it from binding to host cells. This compound has been shown to be effective against hepatitis B virus and galleria mellonella (a type of wax moth). 4-O-Acetylneuraminic acid has also been shown to be effective in inhibiting the replication of Influenza A virus strains that are resistant to neuraminidase inhibitors such as zanamivir and oseltamivir.</p>

<p>Ulvans are structural polysaccharides present in the cell walls of green algae such as Ulva armoricana, Ulva rotondata, Ulva rigida, Ulva lacterca and Ulva pertusa. They are highly sulphated and contain rhamnose 3-sulphate, xylose, xylose 2-sulphate, glucuronic acid and iduronic acid residues.  Ulvan has several potentially valuable functionalities such as gel formation for agricultural and food applications. It has also an anticoagulant, antioxidant, antihyperlipidemic and antitumor activities that are attractive for pharmaceutical applications.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Methyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a xylose sugar that is found in the leaves of Nepeta cataria. It has shown to inhibit bacterial growth by binding to DNA and RNA, as well as inhibit transcription, translation, and replication. Methyl 2-acetamido-2-deoxy-b-D-glucopyranoside also binds to cardiac channels and inhibits their activity. This compound has been shown to have anti cancer effects on prostate cancer cells in mice. Furthermore, it inhibits microbial metabolism in vitro by inhibiting the enzyme acetolactate synthase. Methyl 2-acetamido-2-deoxy-b-D -glucopyranoside has also been shown to be an effective treatment for autoimmune diseases such as multiple sclerosis and rheumatoid arthritis in mice.</p>

<p>2,3,5-Tri-O-benzyl-D-lyxofuranose is a custom organic synthesis. The product is an Oligosaccharide and Polysaccharide that belongs to the carbohydrate family. It can be used for methylation reactions and click chemistry modifications with other molecules. This product has been found to have high purity, and it can be used in various applications such as Fluorination, complex carbohydrate, and Modification. 2,3,5-Tri-O-benzyl-D-lyxofuranose is a monosaccharide sugar that has a molecular weight of 327.24 g/mol and a melting point of 155°C.</p>

<p>Phenyl 2,3,4-tri-O-acetyl-b-D-thioglucuronide methyl ester is a custom synthesis. It is a complex carbohydrate with an Oligosaccharide and Polysaccharide structure. The modification of saccharides with Methylation, Glycosylation, or Carbohydrate changes the chemical properties of this compound. Phenyl 2,3,4-tri-O-acetyl-b-D-thioglucuronide methyl ester has a CAS No. 62812-42-2 and is also known as sugar. This compound is fluorinated at the phenolic hydroxyl group to produce a stable molecule with high purity.</p>

<p>2,5-Anhydro-6-azido-3,6-dideoxy-L-arabino-hexonic acid methyl ester (ADAEM) is a modified sugar that can be used as a building block for oligosaccharides and polysaccharides. ADAEM is a monosaccharide with six hydroxyl groups. This modification of the sugar molecule prevents it from participating in glycosidic bond formation. ADAEM has been shown to be resistant to enzymatic degradation and has high purity. It is also stable at high temperatures and pH ranges.</p>

<p>Methyl 3-Deoxy-3-fluoro-6-O-triphenylmethyl-b-D-glucopyranoside is a synthetic sugar that belongs to the class of carbohydrates. This compound is a modification of saccharides, which are oligosaccharides composed of several sugar molecules. Methyl 3-Deoxy-3-fluoro-6-O-triphenylmethyl-b-D-glucopyranoside is a monosaccharide that has been modified with fluorination and methylation. It can be custom synthesized according to customer specifications, and it is available in high purity. The product can be used as an intermediate in glycosylation reactions or click chemistry reactions.</p>

<p>3,4:5,6-Di-O-isopropylidene-D-glucitol is a chemical compound that belongs to the class of aldehydes. It has been shown to catalyze the reaction between alcohols and amides in the presence of an acid or base catalyst. The product of this reaction is an amide with an isopropylidene group on one side. 3,4:5,6-Di-O-isopropylidene-D-glucitol also has two chiral centers and can be used to synthesize stereoselective aldoses, such as D-(+)-gluconic acid and L-(+)-gluconolactone.</p>

<p>N-Propanoyl mannosamine is a biochemical that belongs to the group of glycoconjugates. It is an intracellular messenger that modulates the concentration of intracellular calcium and controls the release of gamma-aminobutyric acid (GABA). N-Propanoyl mannosamine has been shown to stimulate axonal growth in cell culture, which is mediated by the polysialic acid receptor. This molecule also has a role in human osteoblast differentiation and bone formation.<br>N-Propanoyl mannosamine can be synthesized from dopamine and erythrose via a series of reactions involving acidification, oxidation, reduction, and decarboxylation. The synthesis of this molecule requires blood group O as an acceptor.</p>

<p>3-Deoxy-D-glucosone is a compound that belongs to the group of monosaccharides and has a basic structure. It can be found in many types of biological samples, including blood. The x-ray diffraction data for 3-deoxy-D-glucosone shows an asymmetric unit of two molecules with a coordination geometry of 2.3. This compound is known to have high protein oxidation rates, which are caused by dna binding activity. 3-Deoxyglucosone has been shown to be involved in the pathogenic mechanism of many types of cancers.</p>

<p>Useful starting point and intermediate in the synthesis of lacto-oligosaccharides</p>

<p>Neocarrabiose is a low-energy, hydrogen-bonded sugar that has an optimum concentration of 0.5 M. It is found in the basic structure of oligosaccharides and belongs to group p2. Structural analysis has revealed that Neocarrabiose has a denaturation temperature of 98 °C. Clinical studies have shown that Neocarrabiose may be effective in treating influenza virus, although it is not currently approved for this use. Neocarrabiose can be used as a molecule to form intramolecular hydrogen bonds in organic synthesis and magnetic resonance spectroscopy.</p>

<p>2,3-O-Isopropylidene-L-gulonic acid-1,4-lactone is a synthetic sugar that has been fluorinated. The methyl group at the C2 position of this compound can be modified by various methods to give different derivatives. 2,3-O-Isopropylidene-L-gulonic acid-1,4-lactone is an oligosaccharide that is found in natural glycosides and saccharides. It is also used for click chemistry modifications in complex carbohydrate chemistry. This compound is CAS number 94840-08-1.</p>

<p>1,2,3-Tri-O-methyl-a-D-glucopyranose is a sugar that is used in glycosylation and fluorination reactions. This product can be custom synthesized to your specifications. It is available in high purity and with a variety of modifications. 1,2,3-tri-O-methyl-a-D-glucopyranose has been modified with methyl groups at the C1 and C6 positions. These modifications are useful for studies on glycosylation and fluorination reactions.</p>

<p>Diethoxy phosphonyl 4,7,8,9-tetra-O-acetyl-N-acetyl-D-neuraminic acid methyl ester is a glycosylation agent that is used in the synthesis of complex carbohydrates. It is a methylated derivative of 4,7,8,9 tetra-O-acetyl neuraminic acid and can be used to modify the polysaccharide structure. This product has been shown to react with saccharides and oligosaccharides in a click reaction to produce fluorinated derivatives. Diethoxy phosphonyl 4,7,8,9 tetra-O-acetyl neuraminic acid methyl ester is also available as a custom synthesis.</p>

<p>2-Azido-2-deoxy-L-glucopyranose is a Custom synthesis, modification and fluorination of methylated glucopyranosides. This compound has been shown to be effective in the synthesis of mono-, oligo-, and polysaccharides. 2-Azido-2-deoxy-L-glucopyranose is used for the preparation of glycosylation reagents. It can also be used to modify saccharide chains with azide or alkyne functionalities. 2-Azido-2-deoxy-L-glucopyranose is an important building block for the synthesis of complex carbohydrates, such as polysaccharides, glycosylation reagents, and click chemistry compounds.</p>

<p>N-Benzyl-3,5-dideoxy-3,5-imino-D-lyxofuranose is a fluorinated sugar with a complex carbohydrate. It is synthesized by glycosylation of N-benzylglycine and D-lyxofuranose. This compound can be used for the synthesis of glycoproteins, polysaccharides and other complex carbohydrates. It has been modified using methylation and click chemistry to produce a wide range of derivatives. The compound can be used for research purposes in glycobiology, biochemistry, and materials science.</p>

<p>Methyl 2,4-di-O-methyl-α-D-galactopyranoside is a synthetic saccharide that has been modified with methyl groups at the C2 and C4 positions.</p>

<p>Allyl 3,4-di-O-benzyl-2-O-(2-naphthylmethyl)-a-D-galactopyranoside is a synthetic carbohydrate with a complex structure. It is a modification of a D-galactopyranose sugar and has been glycosylated and methylated. This compound contains an allyl group that has been fluorinated at the 3 position.</p>

<p>Glycosyl-donor for syntheses of N-acetylgalactosamine-glycoconjugates</p>

<p>4-Methoxyphenyl 2-deoxy-4,6-O-(4-methoxybenzylidene)-2-phthalimido-b-D-glucopyranoside is a complex carbohydrate that has been modified with methylation and glycosylation. This product can be used for custom synthesis and is a high purity product. It is soluble in water. The CAS number for this compound is 57810-97-0. The molecular weight of this product is 576. The chemical formula for this compound is C24H28N2O8F3O7, which corresponds to an empirical formula of C24H28N2O8F3O7.</p>

<p>Please enquire for more information about 3-Deoxy-3-fluoro-D-galactose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Competitive inhibitor of glucosylceramidase (GlcCer), which catalyses the first step in glycosphingolipid (GSL) synthesis. This compound is a promising candidate for substrate reduction therapy in Sandhoff disease, where it decreases the rate of GSL biosynthesis and counterbalances the impaired rate of ganglioside catabolism.</p>

<p>1,6:2,3-Dianhydro-4-O-(2,3-di-O-benzyl-4,6-O-benzylidene-b-D-glucopyranosyl)-b-D-mannopyranose is a complex carbohydrate that is synthesized from 1,6:2,3 dianhydro 4 O-(2,3 di O benzyl 4 6 O benzylidene b D glucopyranosyl) b D mannopyranose and has a molecular weight of 576. It contains two monosaccharides that are bound together by a glycosidic linkage. The monosaccharides are ribose and mannose. The structure of this compound includes modifications such as methylation, click modification, fluorination and sulfonation. This compound can be used in the synthesis of oligosaccharides and polysaccharides. This</p>

<p>Used in synthetic organic chemistry and natural product synthesis. Induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. It is used for synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.</p>

<p>D-Glucose 6-phosphate, monosodium salt is a natural compound found in honeybush (Cyclopia species) and other plants. The compound is also found in the human body as a result of its synthesis from glucose. D-Glucose 6-phosphate, monosodium salt is an inhibitor of NADPH cytochrome P450 reductase, which is an enzyme that converts NADPH to NADP+. This inhibition prevents the formation of nadph and causes an accumulation of reduced nicotinamide adenine dinucleotide (NADH), which leads to the inhibition of cell growth. D-Glucose 6-phosphate, monosodium salt has been shown to inhibit cancer cells and bacterial growth. It does this by inhibiting enzymes such as cytosolic phosphoglycerate kinase and phosphofructokinase.</p>

<p>N-2,4-Dinitrophenyl-deoxynojirimycin (DNPDNJ) is a methylated derivative of deoxynojirimycin. It is an inhibitor of glycosylation that can be used to study the structure and function of carbohydrates. DNPDNJ is a synthetic saccharide that can be custom synthesized. Click modification and modification with Oligosaccharides are common modifications for DNPDNJ. DNPDNJ is available in high purity and has been fluorinated for use in fluorescence studies.</p>

<p>6-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is a fluorinated carbohydrate that belongs to the group of saccharides. It is a monosaccharide and can be custom synthesized for specific purposes. This product has been modified with click chemistry, methylation, and glycosylation. 6-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is soluble in water and has high purity.</p>

<p>Dideoxyrhamnojirimycin is a synthetic drug that has been modified to have the same structure as natural dideoxyribonucleosides. It is used in the treatment of myelodysplastic syndrome and thalassemia major. Dideoxyrhamnojirimycin inhibits DNA synthesis by blocking the incorporation of deoxyribonucleotides into DNA, which prevents cell division and stops the spread of cancer cells. Dideoxyrhamnojirimycin also has anti-inflammatory effects by inhibiting prostaglandin synthesis.</p>

<p>2-Azido-2-deoxy-3,5-O-benzylidene-D-lyxono-1,4-lactone is a custom synthesis that is methylated with an azide group. It has been modified with a click reaction to attach an oligosaccharide or polysaccharide and then fluorinated. The modification of this product is not limited to methylation, but includes many other modifications such as fluoroquinolone resistance. 2-Azido-2-deoxy-3,5-O-benzylidene -D-lyxono--1,4--lactone can be used for the preparation of complex carbohydrates. This product can also be used in the synthesis of monosaccharides and sugars.</p>

<p>5-Azido-5-deoxy-2,3-O-isopropylidene-D-gulono-1,4-lactone is a carbohydrate that has been modified by the addition of an azide group. Carbohydrates are complex carbohydrates that consist of monosaccharides linked together to form polysaccharides. They are sugar molecules that act as a source of energy for living organisms. 5-Azido-5-deoxy-2,3-O-isopropylidene -D gulono 1,4 lactone is a monosaccharide which can be methylated and glycosylated with other sugars to form a polysaccharide. It is also fluorinated and saccharide. This compound belongs to CAS No. 144948–71–8 and has the molecular formula C6H8N2O7F9O6.</p>

<p>2,3,5-Tri-O-benzyl-L-lyxofuranose is an acetal that is prepared by hydrolysis of 2,3,5-tri-O-benzylglycol with sodium methoxide in methanol. It can be made from the dimethyl acetal by displacement with sulphonate. The aldehyde group can be converted to an acetal by reaction with ethylene glycol and hydrochloric acid. The displacement of the aldehyde group with methoxide produces the acetal. Dimethyl acetals are also displaced by methyl iodide to produce aldehydes. Acetals are readily hydrolysed and acidic hydrolysis produces the corresponding alcohols.</p>

<p>Methyl a-D-thiomannopyranoside is a synthetic, fluorinated carbohydrate. It is an intermediate in the synthesis of complex carbohydrates that contain saccharide and oligosaccharide moieties. Methyl a-D-thiomannopyranoside can be modified by glycosylation or methylation reactions to produce desired products.</p>

<p>5-O-Acetyl-1,2-O-isopropylidene a-D-xylofuranose is a fluorinated carbohydrate that is synthesized from acetylene gas and the sugar 1,2-O-isopropylidene. It is a complex carbohydrate that can be used as an additive in the food industry. 5-O Acetyl 1,2-O isopropylidene a D xylofuranose has been shown to act as an inhibitor of bacterial growth. It also has the ability to inhibit methylation and glycosylation reactions by competitively binding to the enzyme UDP-Nacetylglucosamine pyrophosphorylase. 5 O Acetyl 1,2 - O isopropylidene a D xylofuranose can be custom synthesized with high purity and it can be modified with methylation or glycosylation.</p>

<p>A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus vesiculotus, Ecklonia (illustrated), Alaria and Cladosiphon) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta.<br>The fucose content of this fucan is approx. 19.0% and it also contains galactose (approx. 12.0%), uronic acid (approx. 25.5%) and sulfate (approx. 19.1%).<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>a-D-Mannose-1-phosphate ammonium salt is a modification of an oligosaccharide, a carbohydrate that is complex in structure. It is a custom synthesis and has high purity. This product is also synthetic and monosaccharide, methylation, glycosylation, and fluorination have been performed on it. The CAS No. for this compound is 1388225-12-4.</p>