Glycoscience

<p>Methyl 3,5-di-O-(p-chlorobenzoyl)-a-D-ribofuranoside is an organic compound. It is a synthetic product that is used in the synthesis of saccharides and polysaccharides. This chemical can be modified with Click chemistry to create a glycosylate or fluorinated complex carbohydrate. The compound has CAS number 62700-92-3 and can be custom synthesized to meet customer specifications.</p>

<p>(S)-3-((3aR,5R,6S,6aR)-6-(Benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propane-1,2-diol is a guanosine triphosphatase inhibitor that binds to the enzyme and blocks its activity. It also has anti-cancer properties due to its ability to inhibit DNA methylation. The drug is activated by nitro groups in the presence of formaldehyde or formic acid to give 3-(N-nitrosomethyl)benzoyloxymethyl butyrylguanine (NMGB). This metabolite is then hydrolyzed into an aldehyde and dialkylamino group which are thought to be responsible for the anticancer activity. NMGB inhibits cancer cell growth by inhibiting protein synthesis and reducing metabolic activities.</p>

<p>4-(3-(2,3-O-Isopropylidene-lyxofuranos-5-yl)propan-2-one-1-yl)piperidine-2,6-dione is a high purity custom synthesis sugar. It is synthesized by Click modification, Fluorination, Glycosylation and Synthetic. 4-(3-(2,3-O-Isopropylidene-lyxofuranos-5-yl)propan-2-one 1 - yl)piperidine 2,6 dione has CAS No., Oligosaccharide and Carbohydrate as its properties. It is a saccharide which belongs to the class of complex carbohydrate.</p>

<p>In addition to the β-glucans from cereals, another group of β-glucans are found in the cell walls of yeast (Saccharomyces cerevisiae), bacteria and fungi, with significantly differing physicochemical properties dependent on source. Typically these β-glucans form a linear backbone with 1,3 β-glycosidic bonds but vary with respect to molecular mass, solubility, viscosity, branching structure, and gelation properties, causing diverse physiological effects in animals.  They are structural components in the cell walls of Saccharomyces cerevisiae and to provide stability, they have a few b-1,6 branch points that lock into other cell wall components (1 in 5 glucose residues). So in any extraction you get a few 1,6 linked glucose residues ~5%.<br>The yeast and fungal β-glucans have been investigated for their ability to modulate the immune system. They are also used in various nutraceutical and cosmetic products, as texturing agents, and as fibre supplements. Their detailed molecular structures are key to the physical properties that they exhibit, such as water solubility, viscosity, gelation properties and physiological functions.<br>The image was kindly provided by Dr. Chris Lawson.</p>

<p>4-Methoxyphenyl 4-O-{4-O-[[2-O-Ac-3-O-[2,4-di-O-(3,4,6-tri-O-Ac-2'-deoxy-[2,3]-Bn] -b'-DGlc]-3,6'-di-'O-[(3',4',6'-tri-'O-'Ac)-2'-deoxy-[2'', 3''] -Bn]-a'-DMan]] -b'-DMan]] -3,6'-di-'O-[(3',4',6'--tri-'O-'Ac)-2' ',' 3'' ',' 6'' '--Deoxy-[2' ', 3' ',' 4'' ', 6'' '--Bn] -a'-DMan]] -b' DMan]] -6'-Octaacetate], is a complex carbohydrate that has been modified with a methyl</p>

<p>Methyl cellulose is a water-soluble polymer that is used as a binder or thickener in pharmaceutical, food, and ceramic processing applications. Methylcellulose has an unusual lower critical solution temperature (LCST) between 40 °C and 50 °C. At temperatures below the LCST it is readily soluble in water; above the LCST it is not soluble, which has a paradoxical effect that heating a saturated solution of methylcellulose will turn it solid, because methylcellulose will precipitate out. The temperature at which this occurs depends on DS-value, with higher DS-values giving lower solubility and lower precipitation temperatures because the polar hydroxyl groups are masked.</p>

<p>Methyl 2,3,4-tri-O-benzyl-6-O-triisopropylsilyl-a-D-galactopyranoside is a synthetic oligosaccharide that has been modified with fluorination and methylation. It belongs to the class of carbohydrates and is used in custom synthesis. This product can be used to modify glycosylated proteins and nucleic acids.</p>

<p>3,6-Anhydro-1,2-O-isopropylidene-7-O-tert butyldimethylsilyl-D-glycero-D-altroheptitol is a methylated saccharide that belongs to the class of polysaccharides. It is an oligosaccharide with a complex carbohydrate structure and has been custom synthesized for use in click chemistry. 3,6 Anhydro -1, 2 - O - isopropylidene -7 - O - tert butyldimethylsilyl - D glycero D altroheptitol has been fluorinated to improve its solubility and stability. This product has high purity and is available in bulk quantities.</p>

<p>6-O-Trityl-D-mannopyranose is a modified sugar that has been synthesized for use as a glycosylation agent. It is an O-glycoside of mannose and is usually used in the synthesis of complex carbohydrates. 6-O-Trityl-D-mannopyranose can be fluorinated, methylated, or click modified to produce desired derivatives. This product can also be used to modify saccharides or oligosaccharides.</p>

<p>1-(3'-Azidopropyl)-2-deoxy-4-O-[3-O-(p-phenoxybenzyl)-b-D-galactopyranosyl]-2-phthalimido-b-D-glucopyranoside is a modification of an oligosaccharide. It is synthesized by the methylation and glycosylation of a monosaccharide, then fluorinated and saccharified. 1-(3'-Azidopropyl)-2-deoxy-4-O-[3-O-(p-phenoxybenzyl)-b -D -galactopyranosyl]-2 -phthalimido b -D -glucopyranoside is a white powder that can be used in the synthesis of complex carbohydrates.</p>

<p>2a,3b,19a-trihydroxyurs-12-en-28-oic acid 28-b-D-glucopyranosyl ester is a glycosylated complex carbohydrate that can be methylated, fluorinated, or custom synthesized. It is typically used as an intermediate in the synthesis of polysaccharides, saccharides and oligosaccharides.</p>

<p>This is a custom synthesis, modification, and fluorination of a polysaccharide. The monosaccharide units are methylated and then modified with a click reaction. The saccharides are glycosylated with 2-O-a-D-mannopyranosyl moieties for the purpose of increasing their water solubility. This saccharide has been synthesized by the modification of an oligosaccharide that has been modified to include a hydroxyl group. The carbohydrate is complex and contains many different types of sugars including glucose, mannose, and galactose.</p>

<p>Monogalactosyldiacylglycerol (MGDG) is a polyunsaturated fatty acid, specifically a galactolipid. MGDG is synthesized by plants and plays an important role in plant physiology. MGDG is involved in the regulation of transcription and translation and also has anti-cancer properties. It has been shown that MGDG can inhibit the proliferation of breast cancer cells such as MDA-MB-231 cells through its interactions with miR-205, a microRNA that regulates cellular growth, differentiation, and apoptosis. The biochemical properties of MGDG are similar to those of diacylglycerol (DAG), which is also involved in transcriptional regulation. It has also been shown that MGDG inhibits the growth of MDA-MB-231 cells when exposed to high salt concentrations.</p>

<p>Methylation of a saccharide is the covalent addition of a methyl group to one of the hydroxyl groups. This process may be achieved through an electrophilic substitution reaction with a methylating agent such as dimethyl sulfate. In the case of polysaccharides, this process can be carried out in vitro using enzymes called glycosyltransferases. The mechanism for glycosyltransferase-mediated methylation was elucidated by Michaelis and Menten in 1913.</p>

<p>Specific, potent and competitive inhibitor of α-L-fucosidase with Ki of 10 nM. In human breast cancer cells, it causes increase of fucosylation on cell surface molecules such as Lewis X antigen (CD15) and CD44 glycoprotein. The 1-deoxyfuconojirimycin treatment increases invasiveness of cancer cells.</p>

<p>1-O-Acetyl-2-O-benzoyl-3-O-tert-butyldimethylsilyl-L-threofuranose is a carbohydrate that can be synthesized to serve as a monosaccharide. Carbohydrates are polysaccharides composed of repeating units of sugar, which may be either glucose or fructose. This carbohydrate has been modified with fluorination and acetylation. It can also be modified with methylation, click modification, or polysaccharide synthesis. This product is custom made and can be ordered in high purity for research purposes.</p>

<p>2,4-Di-C-methyl-3,4-isopropylidene-D-arabinonic acid gamma-lactone is a custom synthesis that has been modified with fluorination and methylation. It is a monosaccharide that can be found in synthetic oligosaccharides and saccharides. This product is CAS No. 9011-05-2.</p>

<p>Please enquire for more information about Glycogen, ex oyster including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Hyaluronic acid potassium, from bacteria including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>Neu5GcAc[1Me,4789Ac]a(2-6)Gal[24Bz,3Bn]-b-MP is a custom synthesis of an oligosaccharide. This complex carbohydrate has a CAS No. and has been modified to include methylation, glycosylation, and click modification. The sugar is a high purity fluorinated synthetic saccharide with a glycosylation site at the reducing end of the chain.</p>

<p>2,3,6-Tri-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetylaDglucopyranosyl)-aDglucopyranosyl)-aDglucopyranosyl bromide is a hexasaccharide that mimics the natural structure of deacetylated β1→4 glucans. It has been synthesized by electrochemical reduction of acetobromoglucose and coupling with glycomimetics. 2,3,6 Tri O acetyl 4 O (2 3 6 tri O acetyl 4 O (2 3 4 6 tetra O acetyl a D glucopyranos yl) a D glucopyranos yl) a D glucopyranos yl bromide is an anomeric mixture of diastereoisomers</p>

<p>Food additive; soil suspension polymer in detergents; thickening agent</p>

<p>Methylation of a saccharide with a methyl group is called methylation. The process is used in the synthesis of many important molecules, including biomedically-relevant compounds such as drugs and natural products. Methylation can be achieved by using various methods, such as by using an organometallic (e.g., Grignard reagent) or electrophilic reagent (e.g., dimethyl sulfate).</p>

<p>N-Acetyl-L-neuraminic acid is a glycosylation compound that is an important component of the cell wall of Gram negative bacteria. It is used in the synthesis of polysaccharides and in the formation of complex carbohydrates. N-Acetyl-L-neuraminic acid has been studied for its potential use as a drug delivery agent due to its ability to inhibit the activity of enzymes such as α-mannosidase, which can lead to tumor metastasis. This compound can be synthesized using methylation, fluorination, and click chemistry, or custom synthesized by ordering specific monosaccharides. N-Acetyl-L-neuraminic acid can also be modified with acetate groups to create an acetylated form for use in chemical analysis or as a substrate for enzymatic reactions.</p>

<p>This complex carbohydrate is a modification of the 6-O-tert.butyl dimethylsilyl]psicofuranose. It is an Oligosaccharide that has been modified with methylation, glycosylation, and Click modification of the sugar moieties. The CAS number for this complex carbohydrate is 10963-29-3, and it has a purity of 99%.</p>

<p>2,5-Deoxyfructosazine is a physiological agent that inhibits the growth of bacteria and fungi. 2,5-Deoxyfructosazine is active against Gram-positive and Gram-negative bacteria, as well as Candida albicans and other yeasts. This drug is effective in inhibiting water vapor loss in the lungs and has been shown to be an effective antimicrobial agent for the treatment of acute lung infections. 2,5-Deoxyfructosazine has been shown to reduce the development of antibiotic resistance in bacteria by preventing cell wall synthesis. The mechanism of action is thought to involve a matrix effect with cationic compounds, which are deposited on the surface of bacterial cells and destroy them by osmotic lysis. 2,5-Deoxyfructosazine also has antidiabetic effects due to its ability to inhibit glucose uptake into cells by binding to glucose transporters on the cell membrane. A reaction mechanism for this process involves hydrogen</p>

<p>Heparin is a linear sulphated polysaccharide comprising contiguous disaccharide units of a uronic acid and a derivative of 2-amino-2-deoxy-D-glucose. The heparin tetrasaccharide can be obtained from the degradation of heparin with the lyase enzymes isolated from Flavobacterium heparinum, which yields oligosaccharides terminated at the non-reducing end by the unsaturated unit, 4-deoxy-α-L-threo-hex-4-enopyranosyl uronic acid or its 2-0-sulphated derivative. The major product following lyase degradation is the trisulphated derivative DUA-2S + GlcNS-6S (unsaturated disaccharide). Other oligosaccharides such as the tetrasaccharide, illustrated below, can be produced by the lytic degradation of heparin (Moffat, 1991).</p>

<p>5-Keto-D-gluconic acid potassium salt is a custom synthesis of 5-keto-D-gluconic acid, which is a monosaccharide. It is modified with fluorination and methylation at the C5 position. The chemical formula for 5-keto-D-gluconic acid potassium salt is C6H7O6K2. This compound has been used in the synthesis of oligosaccharides, saccharides, and polysaccharides.</p>

<p>It is a protected tetrasaccharide intermediate of 3-sialyl-lewis (3'-SLa or sLeA), a tumor-associated carbohydrate antigen.</p>

<p>6-Azido-6-deoxy-1,2:3,4-di-O-isopropylidene-a-D-galactopyranose is a copper complex that is soluble in water. It is used as an initiator for the polymerization of galactose monomers. 6AIDOGAL reacts with azide or diazo compounds to form a cycloaddition reaction and can be used to prepare copolymers by reacting with other monomers such as D-glucose. The temperature range for this reaction is between 20°C and 100°C. This compound has been shown to form stable complexes with Cu(II) ions at temperatures below 0°C.</p>

<p>3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl fluoride is a synthetic glycoside that has been synthesized by the click modification of a fluorinated saccharide. The compound has an acetyl group at C3 and C6 positions with an OCH3 group at the C4 position. This compound has been used in glycosylation reactions to modify the carbohydrate moiety of peptides and proteins. It has also been used in research on complex carbohydrate chemistry.</p>

<p>It is a protected trisaccharide intermediate of 3'-Sialyl Lewis A (also known as 3'-SLa, 3'-sLeA or CA19-9). a tetrasaccharide carbohydrate antigen and a potential target for cancer immunotherapy.</p>

<p>N-Butyl-1-deoxy-2-fluoronojirimycin is a high purity, custom synthesis, sugar modified, fluorination and glycosylation compound. It is a synthetic compound that has been shown to have potential as a cancer therapeutic agent. It is also used as a reagent in the synthesis of glycosides and oligosaccharides. N-Butyl-1-deoxy-2-fluoronojirimycin's CAS number is 2200278-70-0.</p>

<p>Synthesized by the action of zinc chloride on tetra-O-acetylmannose and 1-chloro-3,4,6- tri-0-acetylmannose.  Isolated from partial acetolysates of baker's yeast mannan and Saccharomyces rouxii mannan.</p>

<p>(5S, 8S, 9R) -8- [(4R) - 2, 2- Dimethyl- 1, 3- dioxolan- 4- yl] - 9- hydroxy- 2, 2- dimethyl- 1, 3, 7- trioxaspiro[4.4] nonan- 6- on e is a fluorinated monosaccharide that is synthetically derived. It has been used in glycosylation and polysaccharide synthesis and can be modified with methylation or Click chemistry. This compound is a sugar with CAS number 100741-42-2.</p>

<p>a-D-Glucoheptonic acid sodium salt dihydrate is a diagnostic agent that can be used to diagnose myocardial infarct. It is a glycol ether with a molecular weight of 168, which is used in the preparation of diagnostic agents for the detection of cardiac lesions. The compound is also used as an excipient in pharmaceutical preparations. In addition, it has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>Methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldiphenylsilyl-a-D-mannopyranoside is a synthetic glycosylation product. It has a complex carbohydrate structure and is fluorinated at the O2 position of the sugar. Methylated at the C2 position of the sugar, this saccharide is modified with Click chemistry to attach polysaccharides and oligosaccharides. This product can be custom synthesized in high purity for various purposes.</p>

<p>2-Formylphenyl b-D-glucopyranoside is a phenolic compound that has been shown to have high resistance to transport. It has been shown to possess surface methodology and this property can be used for the delivery of compounds. 2-Formylphenyl b-D-glucopyranoside has also been shown to inhibit plant enzyme activities such as detoxification enzymes and carbohydrate chemistry, which are important in the uptake of natural compounds. In addition, it is able to bind with amines and hydroxyl groups on cells, which may be due to its receptor cell properties. 2-Formylphenyl b-D-glucopyranoside can be synthesized by reacting trifluoroacetic acid with an amine and a hydroxyl group in the presence of glycol ethers or natural compounds.</p>

<p>Resource for synthesis of non-natural ManNAc analogs and mannosaminyl donors</p>

<p>(1R) -1- [(2S, 3R) - 3- Hydroxy- 1- ((4-methoxyphenyl)methyl) - 2- azetidinyl] -1, 2- ethanediol is a sugar compound that can be methylated and modified to make other compounds. The compound's CAS number is 440636-00-0. This product is a carbohydrate that can be used as a modification for saccharides and polysaccharides. It can also be used as a glycosylation agent or an Oligosaccharide. This product is available in high purity and custom synthesis with the desired modifications.</p>

<p>Phenyl β-D-thiogalactopyranoside is a selective inhibitor of galectin-3, which mediates the growth and metastasis of cancer cells. Phenyl β-D-thiogalactopyranoside has been shown to inhibit the binding of galectin-3 to its receptor on cancer cells, thereby blocking the activation of signaling pathways that promote cell proliferation and survival. The crystalline form can be used as a reagent for the determination of glucose in aqueous solutions.</p>

<p>Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an enzyme that catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3 bisphosphoglycerate. GAPDH is involved in glycolysis and the pentose phosphate pathway. It has been shown to be an important player in mediating cellular responses to hypoxia, inflammation, and oxidative stress. The glyceraldehyde-3-phosphate dehydrogenase gene has been found to be mutated in a number of cancers including breast cancer and colon cancer. This gene also has a role in inflammatory lesion development as well as energy metabolism. GAPDH also participates in the biochemical reactions that lead to neuronal death during neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.</p>

<p>2,3,4,6-Tetra-O-pivaloyl-D-glucopyranosyl azide is an oligosaccharide that has been modified for use in the synthesis of complex carbohydrates. It is synthesized through a methylation reaction and then click chemistry. The resulting product is a high purity chemical that can be used to modify saccharides or sugars. 2,3,4,6-Tetra-O-pivaloyl-D-glucopyranosyl azide is a white crystalline solid with CAS No. 1251910-91-4.</p>

<p>2-C-Hydroxymethyl-D-ribose is a sugar that has been found in the cell wall of Mycobacterium tuberculosis. It is also found in some other bacteria, such as Streptomyces coelicolor. 2-C-Hydroxymethyl-D-ribose may be involved in the synthesis of glycan and may have a role in the molybdenum cofactor biosynthesis pathway. This molecule has been shown to have acidic properties, which are most likely due to its hydroxyl groups. The 13C NMR spectrum for this compound shows three peaks at δ H = 138.2, 144.3, and 154.5 ppm corresponding to the ribofuranoside moiety. The skeleton of this molecule was rationalized by attaching an acetaldehyde group to the 2'-hydroxyl group on position C2 of ribose, which is consistent with the observed 13C NMR spectrum. This molecule has</p>

<p>D-Cellotetraose tetradecaacetate is a complex carbohydrate that consists of a single sugar, D-cellotetraose. It is made up of four glucose molecules attached to each other by glycosidic bonds. The modification of this carbohydrate can be done by methylation and glycosylation. The synthesis of this molecule can be custom-made, as it is not found in nature. This product is high purity and has a CAS number: 83058-25-7.</p>

<p>N-[2-(2'-Hydroxyphenylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is a custom synthesis that is a complex carbohydrate. It has CAS No. 55580-06-8. This is an Oligosaccharide that has been modified with saccharides and methylated with glycosylation. Carbohydrate modification includes click modification of sugar and fluorination of synthetic sugars. High purity of this product ensures it will not inhibit reactions in downstream applications as well as be free from contaminants such as endotoxins or heavy metals.</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>L-Glucono-1,5-lactone is a crystalline compound that is used in structural biology and as a growth factor. It has been shown to inhibit the transfer of phosphate from ATP to protein substrates, binding to receptor sites and inhibiting the activity of enzymes such as protein kinase C. L-Glucono-1,5-lactone has also been shown to bind to an aluminum ion with a constant of 0.5 M. This binding inhibits the enzymatic activity of phosphatases that hydrolyze phosphate esters which are important for cellular metabolism.</p>