Compound Libraries
Compound libraries are collections of stored compounds that are widely used to efficiently identify molecules of interest. These libraries are essential tools in research and development, especially in the search for new drugs, as they enable thorough screenings and quality controls to be conducted efficiently. Compound libraries are useful for conducting highly demanding analyses, significantly reducing the cost and time associated with these processes. At CymitQuimica, we offer an extensive range of high-quality compound libraries designed to meet the research and development needs in various scientific and industrial areas. Our catalog includes libraries with a wide variety of compounds, facilitating the identification and development of molecules with therapeutic potential and other innovative applications.
Found 268 products of "Compound Libraries"
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Ingenol Mebutate
CAS:Ingenol-3-angelate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo; it activates a broad range of PKC isoforms and induces apoptosis in acute myeloid leukemia cells by activating the PKC isoform PKCdelta. Ingenol-3-angelate suppresses HIV infection of primary CD4+ T cells through down-modulation of cell surface expression of HIV co-receptors. Ingenol-3-angelate emerges as a unique local chemotherapeutic immunostimulatory debulking agent that could be used in conjunction with immunotherapies to promote regression of metastases.Formula:C25H34O6Purity:95%~99%Molecular weight:430.54120(R)-Ginsenoside Rg3
CAS:20(R)-Ginsenoside Rg3 has shown multiple pharmacological activities and been considered as one of the most promising approaches for fatigue treatment, however, 20(R)-Ginsenoside Rg3 has a low bioavailability after oral administration in human, so, 20(R)-Rg3 can be by intranasal administration, the mechanism was related to the increase of the storage of hepatic glycogen, and the decrease of the accumulation of metabolite such as lactic acid and serum urea nitrogen.Formula:C42H72O13Purity:95%~99%Color and Shape:White powderMolecular weight:785.025Panaxadiol
CAS:Panaxadiol , a ginseng saponin with a dammarane skeleton, selectively interferes with the cell cycle in human cancer cell lines, it inhibits DNA synthesis in a dose-dependent manner with IC50 values ranging from 0.8 to 1.2 μM in SK-HEP-1 cells and HeLa cells, it selectively elevates p21WAF1/CIP1 levels and thereby arrests the cell cycle at G1/S phase by down-regulating Cyclin A–Cdk2 activity.Formula:C30H52O3Purity:95%~99%Color and Shape:White powderMolecular weight:460.743Ginkgetin
CAS:Ginkgetin is a good STAT3 inhibitor , which has anti-inflammatory, neuroprotective, anti-influenza virus and anti-fungal activities. Ginkgetin induces apoptosis in PC-3 cells via activation of caspase 3 and inhibition of survival genes as a potent chemotherapeutic agent for prostate cancer treatment.Formula:C32H22O10Purity:95%~99%Molecular weight:566.518Ginsenoside Rb3
CAS:Ginsenoside Rb3 has anti-myocardial ischemia-reperfusion injury, neuroprotective, antidepressant-like, and antioxidant effects, it also possesses the potential of the clinical use in preventing and treating diabetes. Ginsenoside Rb3 significantly attenuates the changes of creatine kinase activity and lactate dehydrogenase activity, exhibits inhibitory effect on TNFα-induced NF-κB transcriptional activity with an IC50 of 8.2 μM in 293T cell lines, it also inhibits the induction of COX-2 and iNOS mRNA.Formula:C53H90O22Purity:95%~99%Molecular weight:1079.28Ginsenoside Rh3
CAS:Ginsenoside Rh3 is a bacterial metabolite of Rg5, which is the main constituent of heat-processed ginseng, has anti-inflammatory effect in microglia by modulating AMPK and its downstream signaling pathways.Formula:C36H60O7Purity:95%~99%Color and Shape:White powderMolecular weight:604.869Ginsenoside Rb2
CAS:Ginsenosides, which are active compounds found in ginseng (Panax ginseng), are used as antidiabetic treatments; ginsenoside Rb2 may inhibit palmitate-induced gluconeogenesis via AMPK-induced SHP by relieving ER stress, a cause of gluconeogenesis.Formula:C53H90O22Purity:95%~99%Color and Shape:White powderMolecular weight:1079.28Ginsenoside Rg3
CAS:Ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells, and the mechanism of their antimetastatic effect is related to inhibition of the adhesion and invasion of tumor cells, and also to anti-angiogenesis activity.Formula:C42H72O13Purity:95%~99%Color and Shape:White powderMolecular weight:785.025Ginsenoside RK1
CAS:Ginsenoside Rk1, one of the main elements of Sung Ginseng, has been confirmed as a new endothelial barrier enhancer recently and has anti-cancer activity, the mechanism involves coordination between inhibition of telomerase activity and induction of apoptosis.Formula:C42H70O12Purity:95%~99%Molecular weight:767.01Ginsenoside Rc
CAS:Ginsenoside Rc (Rc), a protopanaxadiol type ginsenoside, is the active component mainly responsible for the therapeutic and pharmacologic properties of ginseng, which are derived from its suppression of superoxide-induced free radicals, Rc can modulate Forkhead box O (FoxO1)phosphorylation through activation of PI3K/Akt and inhibition of AMPK and FoxO1 acetylation through interaction with CBP and SIRT1, and that this leads to upregulation of catalase under conditions of oxidative stress.Formula:C53H90O22Purity:95%~99%Color and Shape:White powderMolecular weight:1079.28Isoginkgetin
CAS:Isoginkgetin is a MMP-9 inhibitor, also a pre-mRNA splicing inhibitor with IC 50 of 30 uM. Isoginkgetin can up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. Isoginkgetin has anti-tumor activity, it can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression.Formula:C32H22O10Purity:95%~99%Molecular weight:566.518
