Enzyme, Peptide and Protein Related Compounds

<p>N-Succinimidyl 4-(p-maleimidophenyl)butyrate is a fatty acid that has been shown to regulate the effector proteins of cell surface receptors. It has been shown to be site specific, with water permeability and a molecule size of about 200 Daltons. It is able to bind to the regulatory sites on proteins and inhibit their function. The binding of N-succinimidyl 4-(p-maleimidophenyl)butyrate to antibodies can cause an antibody response in humans and other mammals. Additionally, this fatty acid can also be used as a substrate for protein synthesis. N-Succinimidyl 4-(p-maleimidophenyl)butyrate binds to the subunits of proteins by hydrogen bonding or hydrophobic interactions, which are necessary for protein synthesis. This compound has been shown to inhibit the messenger RNA (mRNA) production in Galleria mellonella larvae,</p>

<p>1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate (CDAP) is an organic cyanylating agent.  It is reactive under acidic conditions giving CDAP an advantage over other sulfhydryl labeling agents, as it can avoid potential thiol-disulfide exchange.</p>

<p>Glycoprotein IIb/IIIa inhibitor; platelet aggregation inhibitor</p>

<p>N-Ethylamine-2,4,6-triphenyl pyridinium tetrafluoroborate is a chemical reagent that belongs to the group of fine chemicals. It is soluble in water and ethanol, and has a melting point of around 100°C. N-Ethylamine-2,4,6-triphenyl pyridinium tetrafluoroborate is used in organic synthesis as a useful building block or as a research chemical for the production of other compounds. This compound is a versatile building block that can be used in the preparation of complex compounds such as pharmaceuticals. N-Ethylamine-2,4,6-triphenyl pyridinium tetrafluoroborate has been classified as an extremely hazardous substance by the US Department of Transportation due to its high reactivity with water.</p>

<p>Ibutilide is a class III antiarrhythmic drug that acts by inhibiting the rapid influx of calcium ions into cardiac cells. It has been shown to reduce fibrillation in patients with structural heart disease, and also to control ventricular rate in atrial fibrillation. Ibutilide has been found to have synergistic effects when combined with other pharmacological agents, such as amiodarone, procainamide, or lidocaine. This drug should be used cautiously in patients who are on concomitant therapy with digoxin or drugs that may decrease the levels of potassium or magnesium in the blood. The model system for ibutilide-induced torsades de pointes is an analytical method based on reaction solution and a model system.</p>

<p>Cocarboxylase tetrahydrate is a coenzyme form of vitamin B1; cofactor for enzymes involved in carbohydrate catabolism</p>

<p>Potent and selective inhibitor of influenza A and B sialidases (neuraminidases). This compound is a sialic acid analogue that occupies viral neuraminidase active site, inhibits enzyme’s hydrolytic activity and cleavage of sialic acid residues from host cell surface glycans. It therefore prevents shedding newly produced virions from infected cell surface and reduces infection of surrounding cells.</p>

<p>Ethyl S-(+)-4-cyano-3-hydroxybutyrate is a chiral molecule that can be used as a catalyst in the transesterification reaction. It acts by binding to the enzyme and immobilizing it on a solid support, which increases its catalytic activity. The hydroxybutanoate is converted into butyric acid, which is produced at high yield using this method. This process of immobilization increases the kinetic rate of the reaction, making it possible for the product to be obtained more quickly.</p>

<p>A broad-spectrum antibiotic of tetracycline class which inhibits protein synthesis by targeting the 30S ribosome subunit. It has been used in human medicine as well as in veterinary medicine and agriculture.</p>

<p>N-alpha-Acetyl-DL-arginine dihydrate (AAD) is a versatile building block that can be used to synthesize functionalized molecules. AAD is an intermediate for the production of pharmaceuticals and other useful compounds. It is also a reaction component in organic synthesis, and has been shown to have high purity.</p>

<p>Ergotamine D-tartrate is a drug that belongs to the group of nonsteroidal anti-inflammatory drugs. It is used in the treatment of migraine and other headaches. Ergotamine D-tartrate inhibits the production of nitric oxide, which has been shown to be involved in the process of angiogenesis. This drug also has long-term efficacy for headaches and migraines, as well as an anti-migraine effect. Ergotamine D-tartrate binds to specific receptors on neurons called alpha2 adrenergic receptors, which are located on blood vessels in the brain and have been implicated in migraine pathophysiology. These receptors are not present on vessels elsewhere in the body, which makes ergotamine a more selective drug for migraine than other nonsteroidal anti-inflammatory drugs.</p>

<p>Trans-resveratrol-3,4',5-trisulfate trisodium salt is a fine chemical that can be used as a building block for research chemicals and pharmaceuticals. It is often used as a reagent in organic synthesis, due to its solubility in organic solvents. This compound has been shown to have activity against Alzheimer's disease. Trans-resveratrol-3,4',5-trisulfate trisodium salt also has anti-inflammatory properties.</p>

<p>Manganese citrate decahydrate is a diagnostic agent that reacts with human serum to form a complex. The reaction is catalyzed by citric acid and sodium carbonate. The solution containing the manganese citrate decahydrate, which has been dissolved in water and treated with magnesium salt (Mn++), reacts with fatty acids in the serum to form a complex of Mn++, citric acid and sodium carbonate. Manganese citrate decahydrate can be used as an indicator of peroxidase activity, which is an enzyme that catalyzes the oxidation of hydrogen peroxide to produce water vapor and oxygen gas. Manganese citrate decahydrate also acts as a structural analysis tool for the detection of iron-containing proteins such as ferritin or myoglobin.</p>

<p>Triethyl citrate (TEC) is an ester of citric acid, which is a natural compound. It is a reactive chemical that can react with potassium dichromate (K2Cr2O7) to form potassium citrate, or with malonic acid to form triethyl malonate. Triethyl citrate has been used as a reagent in analytical methods for the determination of water permeability and biological properties. In addition, it has been used as a precursor for the synthesis of dimethyl fumarate (DMF). DMF is an anti-inflammatory drug that may be useful in the treatment of multiple sclerosis.</p>

<p>25-Hydroxyvitamin D3 monohydrate is a vitamin D analog that has been shown to reduce elevated levels of parathyroid hormone and improve bone mineral density. It is used for the treatment of chronic kidney disease, hyperparathyroidism, and osteoporosis. 25-Hydroxyvitamin D3 monohydrate has been found to be effective in the treatment of these conditions because it increases the body's production of calcitriol, the active form of vitamin D. Calcitriol promotes calcium absorption in the gut and reduces renal excretion of calcium by inhibiting parathyroid hormone synthesis. This drug also inhibits pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α.</p>

<p>R-(+)-Aminoglutethimide is a potent inhibitor of mitochondrial electron transport and the cleavage enzyme 4-phenylimidazole. It inhibits mitochondrial ATP production by binding to the inner mitochondrial membrane and preventing the passage of electrons from cytochrome c oxidase to oxygen. This drug has been shown to be effective in treating corticotroph adenoma, a benign tumor of the anterior pituitary gland, which is due to excessive secretion of ACTH by the gland. R-(+)-Aminoglutethimide can also be used for treatment of Cushing's syndrome due to its ability to inhibit cortisol synthesis in the adrenal cortex. This drug has been shown to act as a potent inhibitor of progesterone synthesis in bovine and human ovaries, leading to decreased levels of pregnenolone, which is an important precursor for other steroid hormones such as testosterone or estrogens.</p>

<p>Please enquire for more information about rec beta-Defensin 1 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Nesfatin-1 (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Formyltetrathiafulvalene is an amide that contains a radical form. It is synthesized by the coordination of a copper complex with l-tartaric acid and imine. The optical properties of this molecule are sensitive to changes in its environment, such as pH and light intensity. Formyltetrathiafulvalene has been shown to absorb light and emit it again at a longer wavelength, which is the basis for its use in organic light-emitting diodes (OLEDs). Functional groups on the molecule can be used for hydrogen tartrate detection, electrochemical studies, or significant interactions with other molecules.</p>

<p>L-Arginine a-ketoglutarate (1:1) is a water soluble compound that is used as a precursor for the synthesis of polyamines. It is also an intermediate in the urea cycle and can be used to synthesize glutamate, glutamine, and argininosuccinic acid. L-Arginine a-ketoglutarate (1:1) has been shown to improve myocardial function and reduce infarct size in animal models. This drug has also been shown to augment neuroprotective properties of metoprolol succinate on cerebellar Purkinje neurons in vitro. The degradation of L-arginine a-ketoglutarate (1:1) by monoamine oxidase B produces hydrogen peroxide, which may be responsible for its cardioprotective effects.</p>