Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 837 products of "Antifungals"
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Bitertanol
CAS:<p>Bitertanol (KWG 0599) is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis.</p>Formula:C20H23N3O2Purity:99.88%Color and Shape:Clear Browm Clear LiquidMolecular weight:337.42N-Chloro-2,2,6,6-tetramethyl-4-piperidyl Methacrylate
CAS:Controlled Product<p>Applications A new N-halamine monomer was synthesized and used to prepare water-based polymeric N-halamines by emulsion polymn. Also, the compound was tested for antibacterial activity against Candida albicans, Staphylococcus aureus, and Escherichia coli.<br>References Kohl, H., et al.: J. Pharm. Sci., 69, 1292 (1980), Greenberger, P., et al.: Clin. Allergy Immunol., 16, 449 (2002), Gant, V., et al.: J. Antimicrob. Chemother., 60, 294 (2007), Pestka, J., et al.: Toxicol. Sci., 104, 4 (2008),<br></p>Formula:C13H22ClNO2Color and Shape:NeatMolecular weight:259.77Curvulin
CAS:Controlled Product<p>Applications Curvulin is a phototoxin that inhibits microtuble assembly.<br></p>Formula:C12H14O5Color and Shape:Off-WhiteMolecular weight:238.24(R)-(-)-2-Oxothiazolidine-4-carboxylic Acid
CAS:Controlled ProductFormula:C4H5NO3SColor and Shape:NeatMolecular weight:147.15Dictamnine
CAS:Controlled Product<p>Applications Dictamnine is an herbal extract from the root of Dictamnus dasycarpus, and exhibits anti-microbial activity against bacteria and fungi. Phytotoxic agent.<br>References Guo, N. et al.: Yeast., 25, 631 (2008); Schempp, C. et al.: Planta. Med., 72, 941 (2006);<br></p>Formula:C12H9NO2Color and Shape:NeatMolecular weight:199.21Benzyl 2-(Chlorosulfonyl)-3-methylbenzoate
CAS:Controlled ProductFormula:C15H13ClO4SColor and Shape:NeatMolecular weight:324.779Benzotriazol-1-ylacetic Acid
CAS:Controlled Product<p>Applications Benzotriazol-1-ylacetic Acid is used as a reagent in the synthesis of benzotriazole imidazoline compounds which are used as metal corrosion inhibitors. Benzotriazol-1-ylacetic Acid is also a reagent in the synthesis of N-(benzo[1,2,3]triazol-1-yl)-N-((benzyl)acetamido)phenyl carboxamides which are used as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors.<br>References Turlington, M., et al.: Bioorg, Med. Chem. Lett., 23, 6172 (2013); Chen, Y., et al.: Faming Zhuanli Shenqing. CN 103664902 A 20140326. Mar 26, 2014<br></p>Formula:C8H7N3O2Color and Shape:NeatMolecular weight:177.165-Mercapto-1H-1,2,3-triazole Sodium Salt
CAS:Controlled Product<p>Applications 5-Mercapto-1H-1,2,3-triazole Sodium Salt is used as a reactant in the preparation of cephem derivatives as anti-Helicobacter pylori agents in relation to lability towards β-lactamase and potential for causing diarrhea.<br>References Yoshida, Y., et al.: Bioorg. Med. Chem., 8, 2317 (2000);<br></p>Formula:C2H2N3NaSColor and Shape:NeatMolecular weight:123.113-Methylbenzenesulfonic Acid Monohydrate
CAS:Controlled ProductFormula:C7H8O3S·H2OColor and Shape:Light BrownMolecular weight:172.20 + (18.02)5,6-Dehydromethysticin
CAS:Controlled Product<p>Applications 5,6-Dehydromethysticin is a proposed intermediate in the synthesis of 3-Hydroxyhispidin (H943133), a derivative of Hispidin. Hispidin (H436450) is a naturally occuring precursor to fungal luciferin responsible for luminosity in mushrooms.<br>References Lee, Y. et al.: Biol. Pharm. Bull., 31, 10 (1968); Purtov, K. et al.: Angew. Chem. Int. Ed., 54, 8124 (2014);<br></p>Formula:C15H12O5Color and Shape:NeatMolecular weight:272.2531,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole
Controlled Product<p>Applications 1,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole is derived from 5-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazole (B397925), which is a structural isomer of Bifonazole (B383400) that is an anti-fungal agent used in the treatment of skin diseases. Bifonazole causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formula:C41H32N2Color and Shape:NeatMolecular weight:552.71(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Controlled ProductFormula:C13H15F2N3O4SColor and Shape:NeatMolecular weight:347.34TH-302
CAS:Controlled Product<p>Applications TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell<br>References Meng, F. et al.: Mol. Cancer Ther., 11, 740 (2012); Liu, Q. et al.: Cancer Chemother. Pharmacol., 69, 1487 (2012); Sun, J.D. et al.: Clin. Cancer Res., 18, 758 (2012);<br></p>Formula:C9H16Br2N5O4PColor and Shape:NeatMolecular weight:449.04Gibberellin A7 Methyl Ester
CAS:Controlled ProductFormula:C20H24O5Color and Shape:NeatMolecular weight:344.45-Fluoro-2-mercaptobenzothiazole
CAS:Controlled Product<p>Applications 5-Fluoro-2-mercaptobenzothiazole is used as a reagent in the synthesis of [[(benzothiazolyl)thio]methyl]phenyl]furanone derivatives with agrochemical fungicidal activities.<br>References Zhao, P., et al.: Youji Huaxue, 30, 1567 (2010);<br></p>Formula:C7H4FNS2Color and Shape:NeatMolecular weight:185.24α-Butylpiperonyl Alcohol
CAS:Controlled Product<p>Applications Intermediate in the preparation of insecticides, fungicides, and other pesticides.<br>References Wilkinson, C., et al.: J. Agric. Food Chem., 14, 73 (1966), Zhong, W., et al.: J. Chem. Res., 6, 370 (2009),<br></p>Formula:C12H16O3Color and Shape:NeatMolecular weight:208.251-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole
CAS:Controlled Product<p>Applications 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole is an intermediate for the synthesis of Pyraclostrobin-d6 (P840402). Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops.<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Formula:C16H12ClN3O3Color and Shape:NeatMolecular weight:329.742-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester
CAS:Controlled Product<p>Applications 2-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester is an intermediate in the synthesis of (Z)-Azoxystrobin (A965155), a fungicide that inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1<br>References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),<br></p>Formula:C20H13N3O5Color and Shape:NeatMolecular weight:375.332-Methylbenzothiazole-6-carboxylic Acid (~90%)
CAS:Controlled Product<p>Applications 2-Methylbenzothiazole-6-carboxylic Acid (~90%) is a useful research chemical, a reagent for the synthetic studies on fungicidal agents.<br>References Saikachi, H., et al.: Yakugaku Zasshi, 78, 376 (1958); Bosco, M., et al.: Annali di Chimica, 58, 1148 (1968)<br></p>Formula:C9H7NO2SPurity:~90%Color and Shape:NeatMolecular weight:193.22
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