Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 841 products of "Antifungals"
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2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity A; Voriconazole USP Related Compound C<br>Applications 2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (Voriconazole EP Impurity A; Voriconazole USP Related Compound C) is an antifungal activity, particularly toward Candida albicans and Candida parapsilosis<br>References Upadhayaya, R., et al.: Eur. J. Med. Chem., 39, 579 (2004), Sheng, C., et al.: J. Med. Chem., 49, 2512 (2006),<br></p>Formula:C10H7F2N3OColor and Shape:BeigeMolecular weight:223.18Stilbamidine
CAS:<p>Stilbamidine (Ba 2652) has antifungal and anticancer activity and can be used to study multiple myeloma and bladder migratory cell carcinoma.</p>Formula:C16H16N4Purity:97.02% - 97.27%Color and Shape:SolidMolecular weight:264.332-(Trifluoromethyl) Nicotinic Acid
CAS:Controlled ProductFormula:C7H4F3NO2Color and Shape:NeatMolecular weight:191.11Difluocortolone
CAS:Controlled Product<p>Applications Difluocortolone is used as a topical therapy in the treatment of pediatric tinea corporis; a common mycotic infection in children.<br>References Veraldi, S., et al.: J. Dermatol. Treat., 29, 200 (2018)<br></p>Formula:C22H28F2O4Color and Shape:NeatMolecular weight:394.455-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazole
CAS:Controlled Product<p>Impurity Bifonazole EP Impurity B<br>Applications 5-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-Imidazole (Bifonazole EP Impurity B) is a compound derived from Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formula:C22H18N2Color and Shape:NeatMolecular weight:310.39Bisabolol Oxide B
CAS:Controlled Product<p>Applications Bisabolol Oxide B is a metabolite of (-)-α-Bisabolol. In the metabolic pathway was used Glomerella Cingulata, a pathogenic fungus. Bisabolol Oxide A and B are in the composition of chamomile flower.<br>References Hoelzl, J., et al.: J. Biosci., 30, 853 (1975); Gibson, S.E., et al.: Org. Biomol. Chem., 1, 676 (2003);<br></p>Formula:C15H26O2Color and Shape:NeatMolecular weight:238.37Rezafungin acetate
CAS:<p>Rezafungin acetate (Biafungin acetate) is a echinocandin with antibacterial activity, inhibiting 1,3-β-D-glucan synthase.</p>Formula:C65H88N8O19Purity:99.76%Color and Shape:SolidMolecular weight:1285.44Glycocholic Acid Hydrate Sodium Salt
CAS:Formula:C26H42NO6·Na·H2OColor and Shape:White To Off-WhiteMolecular weight:505.62[1,1'-Biphenyl]-4-yl(phenyl)methanol
CAS:Controlled Product<p>Impurity Bifonazole EP Impurity A<br>Applications [1,1'-Biphenyl]-4-yl(phenyl)methanol (Bifonazole EP Impurity A) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formula:C19H16OColor and Shape:NeatMolecular weight:260.335-Amino-1-methyl-4-nitroimidazole
CAS:Controlled Product<p>Applications 5-Amino-1-methyl-4-nitroimidazole is a moiety of Azathioprine (A803350); an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD).<br>References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998)<br></p>Formula:C4H6N4O2Color and Shape:NeatMolecular weight:142.123-(Methoxymethylene)-2(3H)-benzofuranone
CAS:Controlled Product<p>Applications 3-(Methoxymethylene)-2(3H)-benzofuranone is an intermediate in the synthesis of Azoxystrobin (A965150), an strobilurin fungicide.<br></p>Formula:C10H8O3Color and Shape:Off White To BeigeMolecular weight:176.17Snail/HDAC-IN-1
CAS:Snail/HDAC-IN-1 is a Snail/HDAC inhibitor with antimicrobial and anticancer activity, known to reduce Snail protein expression and induce apoptosis, making it useful for the study of solid tumors.Formula:C24H21FN8OSPurity:97.08%Color and Shape:SolidMolecular weight:488.54(±)-α-Fenchol
CAS:<p>Applications (±)-α-Fenchol is found in essential oils from many plants. It has been studied for, insecticidal activity of essential oil from Helichrysum faradifani; antioxidant and antibacterial activity of essential oils from rhizome, leaf and stem of Etlingera sayapensis against growth of Bacillus subtilis, Escherichia coli and Candida albicans.<br>References Benelli G., et al., Nat. Prod. Res., 32, 690-1698 (2018); Mahdavi B., et al., Asian. Pac. J. Trop. Med., 10, 819-826 (2017)<br></p>Formula:C10H18OColor and Shape:NeatMolecular weight:154.25Tropic Acid
CAS:Controlled Product<p>Impurity Ipratropium EP Impurity C<br>Applications Tropic Acid (Ipratropium EP Impurity C) is a benzoic acid derivative and thus carries anti-fungal properties.<br>References Amborabe, B.E. et al.: Plant. Phys. Biochem., 40, 1051 (2002);<br></p>Formula:C9H10O3Color and Shape:Off-WhiteMolecular weight:166.17Famoxadone
CAS:<p>Famoxadone (DPX-JE874) is a fungicide with antifungal activity that induces thyroid dysfunction.</p>Formula:C22H18N2O4Purity:96.14%Color and Shape:SolidMolecular weight:374.393(2H)-Isoxazolone
CAS:Controlled Product<p>Applications 3(2H)-Isoxazolone is a 3-hydroxyisoxazole with fungicidal activity. 3(2H)-Isoxazolone is an impurity of Cycloserine (C988800).<br>References Takahi, Y.: San. Kenk. Nen., 25, 8 (1973);<br></p>Formula:C3H3NO2Color and Shape:NeatMolecular weight:85.06Efinaconazole-N-oxide
CAS:Controlled Product<p>Applications Efinaconazole-N-oxide is a degradation product and potentially a metabolite of the anti-fungal drug Efinaconazole (E435070).<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4O2Color and Shape:NeatMolecular weight:364.39
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