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Antifungals

Antifungals

Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.

Found 874 products of "Antifungals"

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  • CDA-IN-3

    CAS:
    CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.
    Formula:C16H27N3O3S2
    Color and Shape:Solid
    Molecular weight:373.534
  • RMG8-8


    RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).
    Formula:C41H78N8O5
    Color and Shape:Solid
    Molecular weight:763.11
  • HSP90-IN-9


    HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.
    Color and Shape:Solid
  • WQ3810 TFA


    <p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>
    Formula:C24H23F6N5O5
    Purity:99.52%
    Color and Shape:Soild
    Molecular weight:575.46
  • Antifungal agent 16


    <p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>
    Formula:C27H21N5O2S
    Color and Shape:Solid
    Molecular weight:479.55
  • Succinate dehydrogenase-IN-8

    CAS:
    Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).
    Formula:C22H19Cl2F2N5O2
    Color and Shape:Solid
    Molecular weight:494.32
  • Tenellin

    CAS:
    Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.
    Formula:C21H23NO5
    Color and Shape:Solid
    Molecular weight:369.41
  • Yck2-IN-1

    CAS:
    <p>Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.</p>
    Formula:C19H11FN4
    Color and Shape:Solid
    Molecular weight:314.316
  • D75-4590

    CAS:
    <p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>
    Formula:C21H27N5
    Purity:98.56% - 98.85%
    Color and Shape:Solid
    Molecular weight:349.47
  • 4-Hydroxyvoriconazole

    CAS:
    <p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>
    Purity:Min. 95%

    Ref: 3D-AH167809

    10mg
    7,392.00€
  • Rhizocticin A

    CAS:
    Rhizocticin A is a potential inhibitor of threonine synthase.
    Formula:C11H22N5O6P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.3

    Ref: TM-T26074

    5mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product
  • 2,7-Dihydroxynaphthalene

    CAS:
    2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.
    Formula:C10H8O2
    Color and Shape:Solid
    Molecular weight:160.17

    Ref: TM-T67338

    ne
    Discontinued
    Discontinued product
  • Tetraconazole

    CAS:
    Tetraconazole is an agent of pesticides.
    Formula:C13H11Cl2F4N3O
    Color and Shape:Liquid Viscous
    Molecular weight:372.14

    Ref: TM-T20152

    ne
    Discontinued
    Discontinued product
  • Amphotericin A

    CAS:
    <p>Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.</p>
    Formula:C47H75NO17
    Purity:Min. 95%
    Molecular weight:926.09 g/mol

    Ref: 3D-FA177367

    ne
    Discontinued
    Discontinued product