Antivirals
Antivirals are compounds specifically designed to inhibit the replication and spread of viruses, playing a critical role in the treatment and prevention of viral infections. In this category, you will find a comprehensive selection of antiviral agents intended for laboratory research purposes only. These products are essential for studying viral mechanisms, developing new antiviral therapies, and understanding resistance patterns. Researchers can utilize these antivirals to investigate the efficacy and safety of potential treatments, contributing to the advancement of medical science and the development of innovative antiviral drugs. The availability of diverse antiviral agents supports cutting-edge research in virology and enhances our ability to combat viral diseases.
Found 762 products of "Antivirals"
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(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl Acetate
CAS:Controlled Product<p>Applications Darunavir intermediate.<br>References Ghosh, A., et al.: J. Med. Chem., 39, 3278 (1996), Ghosh, A., et al.: Bioorg. Med. Chem. Lett., 1998, 8, 687 (1998), Richman, D., et al.: Nature, 410, 995 (2001), Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003),<br></p>Formula:C8H12O4Color and Shape:NeatMolecular weight:172.18α-Bromoacetosyringone
CAS:Controlled ProductFormula:C10H11BrO4Color and Shape:NeatMolecular weight:275.1(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Triethylammonium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate.<br>References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010);<br></p>Formula:C28H61FN5O14P3Color and Shape:Off White SolidMolecular weight:803.73R 77975
CAS:Controlled Product<p>Applications R 77975 is used to modulate lipophilicity in human rhinovirus capsid binders. It also is used in order to identify potential ativiral agents.<br>References Morley, A. et al.: Bioorg. Med. Chem. Lett., 21, 6031 (2011); Tomkinson, N. et al.: Bioorg. Med. Chem. Lett., 22, 7494 (2012);<br></p>Formula:C21H27N3O3Color and Shape:NeatMolecular weight:369.46Nelfinavir Sulfone
CAS:Controlled Product<p>Impurity Nelfinavir Sulphone Impurity<br>Applications Nelfinavir Sulfone is an impurity of Nelfinavir Mesylate (N389750). It is a COVID19-related research product.<br>References Aymard, G., et al.: J. Chromatogr. B, 744, 227 (2000), Jing, Q., et al.: J. Pharm. Biomed. Anal., 41, 1065 (2006),<br></p>Formula:C32H45N3O6SColor and Shape:NeatMolecular weight:599.781,2,4-Triazole-3-carboxylic Acid
CAS:<p>Impurity Ribavirin EP Impurity C<br>Applications 1,2,4-Triazole-3-carboxylic Acid (Ribavirin EP Impurity C) is a major metabolite of the antiviral agent Ribavirin (R414475).<br>References Miller, J.P. et al.: Ann. N.Y. Acad. Sci., 284, 211 (1977); Catlin, D. et al.: Ribavirin: Broad Spec. Antivir. Ag., 83 (1980); Lin, C.C. et al.: Antimicrob. Ag. Chemother., 50, 2368 (2006);<br></p>Formula:C3H3N3O2Color and Shape:White SolidMolecular weight:113.07Nelfinavir Hydroxy-tert-butylamide
CAS:Controlled ProductFormula:C32H45N3O5SColor and Shape:Off White SolidMolecular weight:583.78[(3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate
CAS:Controlled Product<p>Applications Darunavir intermediate.<br>References Ghosh, A., et al.: J. Med. Chem., 39, 3278 (1996), Ghosh, A., et al.: Bioorg. Med. Chem. Lett., 1998, 8, 687 (1998), Richman, D., et al.: Nature, 410, 995 (2001), Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003),<br></p>Formula:C11H13NO7Color and Shape:NeatMolecular weight:271.22Levovirin
CAS:Controlled Product<p>Applications Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin (R414475) with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.<br>References Ramasamy, K.S. et al.: J. Med. Chem., 43, 1019 (2000); Fang, C. et al.: J. Appl. Toxicol., 23, 453 (2003):<br></p>Formula:C8H12N4O5Color and Shape:NeatMolecular weight:244.20Zanamivir Azide Methyl Ester
CAS:Controlled Product<p>Applications An intermediate used in the preparation of Zanamivir derivatives.<br>References Andrews, D., et al.: Eur. J. Med. Chem., 34, 563 (1999), Altamore, T., et al.: Bioorg. Med. Chem., 14, 1126 (2006),<br></p>Formula:C12H18N4O7Color and Shape:NeatMolecular weight:330.29BCX 4430 hydrochloride
CAS:<p>RNA polymerase (RdRp) inhibitor</p>Formula:C11H15N5O3Purity:Min. 95%Molecular weight:265.27 g/molVicriviroc malate
CAS:<p>Vicriviroc malate is a CCR5 antagonist with action on blocking HIV entry into cells by targeting the CCR5 receptor and is used for research on HIV treatment.</p>Formula:C28H38F3N5O2•C4H6O5Purity:Area-% Min. 90 Area-%Color and Shape:PowderMolecular weight:667.72 g/molAlamifovir
CAS:<p>Alamifovir is an antiviral agent, which is synthetically derived. The mode of action of Alamifovir involves the inhibition of viral replication within host cells by targeting specific viral enzymes crucial for the replication process. This interference with the viral life cycle diminishes the ability of the virus to propagate and spread within the host organism.</p>Formula:C19H20F6N5O5PSPurity:Min. 95%Molecular weight:575.42 g/molTromantadine hydrochloride
CAS:Controlled Product<p>Tromantadine hydrochloride is a synthetic antiviral compound, which is a derivative of adamantane. It originates from chemical synthesis, tailored specifically to target viral processes. Tromantadine hydrochloride primarily exerts its effects by inhibiting the penetration of virus particles into host cells and impeding the subsequent stages of viral replication. This mode of action effectively reduces the viral load and hinders the progression of the infection.</p>Formula:C16H28N2O2•HClPurity:Min. 95%Molecular weight:316.87 g/molViramidine hydrochloride
CAS:<p>Viramidine hydrochloride is an antiviral prodrug with action as a precursor to ribavirin, targeting viral RNA synthesis and is used for research on hepatitis C and other viral infections.</p>Formula:C8H14ClN5O4Purity:Min. 95%Molecular weight:279.68 g/molEquisetin
CAS:<p>Equisetin is a secondary metabolite, which is produced by the fungus *Fusarium equiseti*. It operates predominantly through the inhibition of protein synthesis and interference with cellular processes within target organisms. Equisetin exhibits potent antibacterial and antifungal activities primarily by interfering with cell wall synthesis in bacteria and disrupting key pathways in fungi.</p>Purity:Min. 95%Peramivir
CAS:<p>Selective and potent inhibitor of sialidases (neuraminidases) in influenza A and B viruses. The compound binds tightly to the viral neuraminidase active site in late stages of viral life-cycle. It inhibits shedding sialic acids from host cell surface glycans, which interact with viral hemagglutinin, and consequently prevents release of new viral particles from the host cell surface.</p>Formula:C15H28N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:328.41 g/molGanciclovir, Antibiotic for Culture Media Use Only
CAS:<p>Ganciclovir is an antiviral agent specifically designed for culture media use. It is a synthetic analogue of 2'-deoxy-guanosine, derived from nucleoside compounds, and operates primarily by inhibiting the replication of viral DNA. Its mode of action involves selective phosphorylation by viral kinases, which converts it into ganciclovir triphosphate, a potent inhibitor of viral DNA polymerase, ultimately preventing viral DNA synthesis.</p>Formula:C9H13N5O4Purity:Min. 98.0 Area-%Molecular weight:255.23 g/molDarunavir-D9
CAS:<p>Darunavir-D9 is a prodrug of darunavir, which is an HIV protease inhibitor. Darunavir-D9 has been shown to be bioequivalent in pharmacokinetic parameters to darunavir given as a tablet. The drug exhibits a low plasma concentration profile and high clearance values. This may be due to rapid absorption and distribution of the drug, with a short elimination half-life. Darunavir-D9 also has little effect on the matrix effect and reproducibility of the reaction monitoring assay, making it an ideal candidate for use in clinical trials.</p>Formula:C27H28D9N3O7SPurity:Min. 95%Molecular weight:556.72 g/mol
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