Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 704 products of "Antiparasitics"
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GNF179
CAS:<p>GNF179 is an optimized 8,8-dimethyl IP analog.</p>Formula:C22H23ClFN5OPurity:98.9%Color and Shape:SolidMolecular weight:427.9LASSBio-1985
<p>LASSBio-1985 is an inhibitor of NHLd (nucleoside hydrolase of Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. It exhibits selective toxicity against Leishmania parasites without affecting mammals, showing potential for research in infectious disease treatment.</p>Formula:C18H22N2O7Color and Shape:SolidMolecular weight:378.38CpNMT-IN-1
<p>CpNMT-IN-1 (Compound 11e) is an inhibitor of N-myristoyltransferase (CpNMT) with an IC50 value of 2.5 μM. It also inhibits the growth of microsporidia, demonstrating an EC50 value of 6.9 μM.</p>Formula:C25H25ClN4O4SColor and Shape:SolidMolecular weight:513.008Alkaline tryptase-IN-1
<p>Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.</p>Formula:C29H33BrN2O2SColor and Shape:SolidMolecular weight:553.55TSO-13
<p>TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.</p>Formula:C32H36N4O4S2Color and Shape:SolidMolecular weight:604.78β-Hederin
CAS:<p>β-Hederin has antileishmanial activity. β-Hederin has apoptotic effect on cancer cells, it could be a promising candidate for chemotherapy of breast cancer.</p>Formula:C41H66O11Purity:98%Color and Shape:SolidMolecular weight:734.96Mepartricin
CAS:<p>Mepartricin, a polyene macrolide, exhibits both antifungal and antiprotozoal activities and is extensively utilized in studies related to benign prostatic hyperplasia.</p>Color and Shape:SolidAAP4
<p>AAP4 is a potent inhibitor of OfChi-h and OfHex1, exhibiting Ki values of 29.3 nM and 4.9 μM, respectively. It also demonstrates insecticidal activity against the lepidopteran pest Ostrinia furnacalis.</p>Formula:C21H23BrClN7Color and Shape:SolidMolecular weight:488.811Schizophyllan
CAS:<p>Schizophyllan, a member of the β-glucan family, is an extracellular polysaccharide known for its antitumor, antibacterial, and antiparasitic activities.</p>Color and Shape:SolidAntiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Color and Shape:Odour SolidIle-AMS TFA
<p>Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.</p>Formula:C18H27F3N8O8SColor and Shape:SolidMolecular weight:572.52Antitrypanosomal agent 23
<p>Antitrypanosomal agent 23 is an antiparasitic compound effective against intracellular amastigotes of Trypanosoma cruzi in LLC-MK2 and C2C12 cells, demonstrating activity with IC50 values of 0.10 and 0.11 μM, respectively. It also acts as a weak inhibitor of recombinant Trypanosoma cruzi sialyltransferase (TcTS) with an IC50 of 1.1 mM.</p>Formula:C14H16N4O7Color and Shape:SolidMolecular weight:352.1019Gypsogenic acid
CAS:<p>Gypsogenic acid, a triterpenic acid isolated from Miconia stenostachya, exhibits antibacterial and antitrypanosomal activities. This compound demonstrates minimum inhibitory concentrations (MICs) ranging from 50-200 μg/mL against oral bacterial pathogens including Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus spp., and Streptococcus sobrinus. Additionally, gypsogenic acid can induce the lysis of Trypanosoma cruzi in isolated mouse blood, with an IC50 value of 56.6 μM.</p>Formula:C30H46O5Color and Shape:SolidMolecular weight:486.68Norselic acid B
CAS:<p>Norselic acid B is a naturally occurring compound that can be isolated from the sponge Crella sp. collected in Antarctica. It demonstrates activity against Leishmania parasites.</p>Formula:C29H44O4Color and Shape:SolidMolecular weight:456.657Antiproliferative agent-56
<p>Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.</p>Color and Shape:Odour SolidNitroxynil
CAS:<p>Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.</p>Formula:C7H3IN2O3Purity:99.76%Color and Shape:SolidMolecular weight:290.01Azlocillin sodium salt
CAS:<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formula:C20H22N5NaO6SPurity:97.63% - 98.302%Color and Shape:SolidMolecular weight:483.47ML251
CAS:<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formula:C17H13Cl2N3O4SPurity:99.87%Color and Shape:SolidMolecular weight:426.27Antimalarial agent 43
<p>Antimalarial agent 43 (compound 16c) is an antimalarial compound that exhibits an IC50 value of 0.0151 μM against the 3D7 strain.</p>Color and Shape:Odour SolidFebrifugine dihydrochloride
CAS:<p>Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory</p>Formula:C16H21Cl2N3O3Purity:98.27% - 99.85%Color and Shape:SolidMolecular weight:374.26
