Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 697 products of "Antiparasitics"
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Cinchonidine
CAS:Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.Formula:C19H22N2OPurity:94.96% - 99.87%Color and Shape:White PowderMolecular weight:294.39Antileishmanial agent-26
Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with activity against *Leishmania donovani*, exhibiting an IC50 value of 5.67 μM and a CC50 value of 3.79 μM in THP-1 cells. This compound is applicable for research in tropical diseases.Formula:C23H27FN4O2Molecular weight:410.2118TSO-13
TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.
Formula:C32H36N4O4S2Color and Shape:SolidMolecular weight:604.78Antitrypanosomal agent 16
Antitrypanosomal agent 16 functions as a potent trypanocide, exhibiting an inhibitory concentration 50 (IC50) of 0.04μM against the T.Purity:98%Color and Shape:Odour SolidDXR-IN-1
DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). It exhibits high selectivity for DXR of Plasmodium falciparum with an IC50 of 0.030 μM. DXR-IN-1 impedes the growth of Plasmodium by binding to the active site of DXR and inhibiting its catalytic activity.Formula:C19H24NO5PMolecular weight:377.13921Alkaline tryptase-IN-1
Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.Formula:C29H33BrN2O2SColor and Shape:SolidMolecular weight:553.55Urethane
CAS:Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.Formula:C3H7NO2Purity:99.01%Color and Shape:SoildMolecular weight:89.09Antileishmanial agent-20
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.Formula:C15H16N4O3Purity:98%Color and Shape:SolidMolecular weight:300.31Amprolium
CAS:Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.Formula:C14H19N4·ClPurity:98%Color and Shape:SolidMolecular weight:278.79Doxycycline monohydrate
CAS:Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)Formula:C22H26N2O9Purity:99.97%Color and Shape:SolidMolecular weight:462.4Nanaomycin A
CAS:Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).Formula:C16H14O6Purity:98%Color and Shape:SolidMolecular weight:302.28Ile-AMS TFA
Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.Formula:C18H27F3N8O8SColor and Shape:SolidMolecular weight:572.524-(2-Aminoethyl)amino-7-chloroquinoline
CAS:4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study ofFormula:C11H12ClN3Purity:98.53%Color and Shape:SolidMolecular weight:221.69Antiparasitic agent-22
Antiparasitic agent-22 (Compound 24) is a broad-spectrum antiparasitic compound that inhibits the procyclic form of T. brucei, L. infantum, and L. tropica with IC50 values of 2.41, 5.95, and 8.98 μM, respectively, and the amastigote form of L. infantum with an IC50 of 8.18 μM. It also shows inhibitory activity against the P. falciparum W2 strain with an IC50 of 0.155 μM. Additionally, Antiparasitic agent-22 exhibits low cytotoxicity in THP1 cells, with a CC50 of 64.16 μM.Formula:C18H20BrN3O3Molecular weight:405.0688Azlocillin sodium salt
CAS:Azlocillin sodium, an acylampicillin, is a broad-spectrum antibioticsFormula:C20H22N5NaO6SPurity:97.63% - 98.302%Color and Shape:SolidMolecular weight:483.47Methylclonazepam
CAS:Methylclonazepam is a benzodiazepine with anxiolytic properties. It inhibits the uptake of 5-hydroxytryptamine by Schistosoma mansoni, and its derivatives exhibit anti-Schistosoma mansoni activity.Formula:C16H12ClN3O3Color and Shape:SolidMolecular weight:329.74Antiparasitic agent-20
Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T.Purity:98%Color and Shape:Odour SolidNPD-2975
NPD-2975 (compound 30) is an orally active antitrypanosomal agent effective against Human African Trypanosomiasis (HAT), demonstrating acceptable metabolicFormula:C14H13FN4OPurity:98%Color and Shape:SolidMolecular weight:272.28Sarolaner
CAS:Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).Formula:C23H18Cl2F4N2O5SPurity:99.54% - 99.65%Color and Shape:SolidMolecular weight:581.36Dixanthogen
CAS:Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.Formula:C6H10O2S4Purity:95% - 98%Color and Shape:SolidMolecular weight:242.4
