Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 704 products of "Antiparasitics"
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Diloxanide furoate
CAS:Diloxanide furoate treats mild intestinal Amebiasis and is preferred for asymptomatic cyst carriers.Formula:C14H11Cl2NO4Purity:99.39%Color and Shape:SolidMolecular weight:328.154-Phospho D-Erythronate
CAS:<p>Applications 4-Phospho-D-erythronate is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme.<br>References Tanaka, N., et al.: J. Mol. Biol., 324, 519 (2002), Fitzpatrick, T., et al.: Biochem. J., 407, 1 (2007), Kalliri, E., et al.: J. Bacteriol., 190, 3793 (2008),<br></p>Formula:C4H9O8PColor and Shape:ColourlessMolecular weight:216.089-Methylacridine
CAS:Controlled Product<p>Applications 9-Methylacridine is an derivative of Acridine (A190900), a quinoline derivative used as manufacturing dyes and as an intermediate for the synthesis of antileishmanial agents.<br>References Pathak, D. et al.: Pharma Chemica, 3, 239 (2011); Mathieu, O. et al.: Xenobiotica, 41, 91 (2011); Rubbo, S.D. et al.: Br. J. Exp. Pathol., 28, 1 (1947);<br></p>Formula:C14H11NColor and Shape:NeatMolecular weight:193.24Diclazuril 6-Carboxylic Acid
CAS:Controlled Product<p>Applications Diclazuril 6-Carboxylic Acid is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br>References Fodey, T.L., et al.: J. Immunol. Meth., 323, 31 (2007);<br></p>Formula:C18H9Cl3N4O4Color and Shape:NeatMolecular weight:451.65Bruceantin A
CAS:Controlled Product<p>Applications Bruceantin A acts as an anti-babesial quassinoid, extracted from the fruits of Brucea javanica, also an effective anti-trypanosomal agent in vitro. Cytotoxic agent.<br>References Bawm, S. et al.: Vet. Parasitol., 158, 288 (2008); Elkhateeb, A, et al.: Nat. Prod. Comm., 3, 145 (2008);<br></p>Formula:C26H34O11Color and Shape:NeatMolecular weight:522.542(E)-Cefodizime
CAS:<p>Applications (E)-Cefodizime can be obtained from Ethyl Acetate (E899545) which is a chemical intermediate used in the production of various analgesics, antibiotics and antimalarial agents.<br>References Mutti, F.G., et al.: Adv. Syn. Cata., 354, 3409 (2012); Subudhi, B., et al.: Bull. Chem. Soc., Ethiopia., 26, 455 (2012);<br></p>Formula:C20H20N6O7S4Purity:>80%Color and Shape:NeatMolecular weight:584.6688Gossypol Acetic Acid
CAS:Controlled Product<p>Applications Gossypol is a mixture of natural polyphenols isolated from the cotton plant. It causes spermatogenesis arrest in humans and also functions as an anti-malarial agent. Antiinflammatory. Anticancer.<br>References Huo, M. et al.: Int. Immunopharmacol., 15, 442 (2013); Coutinho, E. et al.: Contraception. 65, 259 (2002); Royer, R. et al.: J. Med. Chem., 29, 1799 (1986);<br></p>Formula:C30H30O8·C2H4O2Color and Shape:Off White SolidMolecular weight:578.612-(Aminomethyl)-4-((7-chloroquinolin-4-yl)amino)phenol Hydrochloride Salt
CAS:Controlled Product<p>Applications 2-(Aminomethyl)-4-((7-chloroquinolin-4-yl)amino)phenol is a metabolite of Amodiaquine (A634200), an antimalarial agent.<br>References Mariga, S.T., et. al.: Acta Tropica, 93, 221 (2005); Natarajan, L., et al.: Arzneim.-Forsch., 22, 1230 (1972); Kracmer, J., et al.: Pharmazie, 29, 773 (1974); Ahmad, I., et al.: Anal. Profiles Drug Subs., 21, 43 (1992)<br></p>Formula:C16H14ClN3O·xHClColor and Shape:NeatMolecular weight:299.75 + x(36.46)Ivermectin B1 Aglycon
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Campbell, W., et al.: Science, 221, 823 (1983); Glaziou, P., et al.: Trop. Med. Parasitol., 45, 253 (1994); Meinking, T., et al.: New Engl. J. Med., 333, 26 (1995); Caly, L., et al.: Antivir. Res., 178<br></p>Formula:C34H50O8Color and Shape:Off White PowderMolecular weight:586.761,4-Bis(trichloromethyl)-2,5-dichlorobenzene
CAS:Controlled Product<p>Applications 1,4-Dichloro-2,5-bis(trichloromethyl)-Benzene is a derivative compound of 1,4-Bis(trichloromethyl)-2-chlorobenzene (B585580), that acts as a reagent for the synthesis of hexachloroxylene derivatives which functions pharmaceutically as antimalaria and as a schistosomicides.<br>References Elslager, E., et al.: J. Med. Chem., 13, 542 (1970)<br></p>Formula:C8H2Cl8Color and Shape:NeatMolecular weight:381.73Aminorex
CAS:Controlled Product<p>Applications Aminorex is a metabolite of Levamisole (L331100). Aminorex is an anorectic stimulant drug of the 2-amino-5-aryl oxazoline class. Aminorex has been shown to have locomotor stimulant effects similar to Methamphetamine (M258795).<br>References Poos, G., et al.: J. Med. Chem., 6, 266 (1963), Watson, A., et al.: Res. Vet. Sci., 45, 411 (1988), Russell, B., et al.: Pharmacol. Biochem. Behav., 51, 375 (1995),<br></p>Formula:C9H10N2OColor and Shape:Off White SolidMolecular weight:162.19rac-Febrifugine Dihydrochloride
CAS:Controlled Product<p>Applications rac-Febrifugine dihydrochloride is the salt of Febrifugine, a bioactive constituent of a Chinese medicinal herb that is characterized by its therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.<br>References Keller, T.L.: Nat. Chem. Bio., 8, 311, (2012); Zhu, S. et al.: Bio. Med. Chem., 17, 4496 (2009);<br></p>Formula:C16H19N3O3·2ClHColor and Shape:NeatMolecular weight:374.26Avermectin A1b (>85%)
CAS:Controlled Product<p>Applications Avermectin A1b is part of a series of drugs that can be used for treating parasitic diseases in animals.<br>References Billi, M. et al.: Braz. Pedido PI, 15pp., (2013)<br></p>Formula:C48H72O14Purity:>85%Color and Shape:NeatMolecular weight:873.082-Hydroxy-3-methylanthraquinone
CAS:<p>Applications 2-Hydroxy-3-methylanthraquinone is a derivative of anthraquinone (A679245) which is an important precursor for many drugs, including Emodin (E523000), Aloe-emodin (A575400), Antimalarials such as Rufgallol, and also Antineoplastics used in the treatment of cancer, such as mitoxantrone (M373425), pixantrone (P552500), and the anthracyclines.<br>References Pan, X., et al.: Biochem. Eng. J., 5, 173 (2000), Macleod, L.C., et al.: Org. Synth., 14:4; (2005); McDonald, M., et al.: Drugs Exp. Clin. Res., 10, 745 (1984); Cavalletti, E. et al.: Invest. New Drugs, 25, 187 (2007);<br></p>Formula:C15H10O3Color and Shape:Dark Green SolidMolecular weight:238.24Alloc Bromoridane
CAS:Controlled Product<p>Applications Alloc Bromoridane is used as an anticoccidial agent. Alloc Bromoridane is an intermediate of Febrifugine and Halofuginone (H102500), as inhibitors of prolyl-tRNA synthetase.<br></p>Formula:C13H20BrNO4Color and Shape:NeatMolecular weight:334.21Diclazuril 6-Carboxamide
CAS:Controlled Product<p>Applications Diclazuril 6-Carboxamide is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br></p>Formula:C18H10Cl3N5O3Color and Shape:NeatMolecular weight:450.66Diclazuril 6-Carboxylic Acid [(4-Chlorophenyl)cyanomethyl]-2,6-dichlorophenyl-4-amide
CAS:<p>Applications Diclazuril 6-Carboxylic Acid [(4-Chlorophenyl)cyanomethyl]-2,6-dichlorophenyl-4-amide is an dimerized impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br></p>Formula:C18H9Cl3N4O4Color and Shape:NeatMolecular weight:451.652-Amino-5-Methylhexane Hydrochloride
CAS:Controlled ProductFormula:C7H17N·HClColor and Shape:White To Off-WhiteMolecular weight:115.22 + 36.46
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