Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 697 products of "Antiparasitics"
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Antileishmanial agent-16
CAS:Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 µM) andFormula:C27H37N5O4Purity:98%Color and Shape:SolidMolecular weight:495.61Fervenulin
CAS:Fervenulin, from Streptomyces sp. CMU-MH021, halts egg hatch (MIC: 30 μg/mL) and kills J2 larvae (MIC: 120 μg/mL) of M. incognita.Formula:C7H7N5O2Purity:99.75%Color and Shape:SolidMolecular weight:193.16Ref: TM-T15277
1mg71.00€5mg136.00€10mg210.00€25mg358.00€50mg500.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)111.00€DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurity:97.8% - 99.76%Color and Shape:SolidMolecular weight:495.43Ref: TM-T27135
1mg90.00€5mg253.00€10mg379.00€25mg640.00€50mg892.00€100mg1,224.00€1mL*10mM (DMSO)275.00€FIKK9.1-IN-1
CAS:FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1,Formula:C22H22N2SePurity:98%Color and Shape:SolidMolecular weight:393.38OfChi-h-IN-2
CAS:OfChi-h-IN-2 (compound TQ19) is a potent inhibitor of OfChi-h, exhibiting a K i of 0.33 μM, and significantly impairs the growth and development of OstriniaFormula:C25H28ClN5O3Purity:98%Color and Shape:SolidMolecular weight:481.98Dehydroemetine
CAS:Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.Formula:C29H38N2O4Purity:98.68% - 99.68%Color and Shape:SolidMolecular weight:478.62ZY-19489
CAS:ZY-19489: Antimalarial, potential single-dose cure, FDA orphan drug status.
Formula:C24H32FN9Purity:>99.99%Color and Shape:SoildMolecular weight:465.57MMV688533
CAS:MMV688533 has antimalarial activity.Formula:C24H15F6N5O2Purity:99.12%Color and Shape:SoildMolecular weight:519.4Ref: TM-T67695
1mg185.00€5mg409.00€10mg605.00€25mg938.00€50mg1,293.00€100mg1,738.00€500mg3,496.00€1mL*10mM (DMSO)509.00€GSK3186899
CAS:GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.Formula:C19H28F3N7O3SPurity:98.35% - 99.61%Color and Shape:SolidMolecular weight:491.53CWHM-1552
CAS:CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.Formula:C22H27F2N3OPurity:99.56%Color and Shape:SolidMolecular weight:387.47SAL-0010042
CAS:SAL-0010042 is an inhibitor of Plasmodium phosphodiesterase β (PDEβ), effectively blocking the hydrolysis of cAMP and cGMP in gametocytes with an IC50 of 48.9 nM, thereby activating PKG and inhibiting the growth and development of Plasmodium (IC50s for 3D7 and Dd2 are 142 nM and 218 nM, respectively). It also inhibits hPDE5 and hPDE6 with IC50 values of 632 nM and 73 nM, respectively.Formula:C15H15FN4OColor and Shape:SolidMolecular weight:286.304MED6-189
CAS:MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.Formula:C17H26N2OColor and Shape:SolidMolecular weight:274.40Arohynapene B
CAS:Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.Formula:C18H22O3Color and Shape:SolidMolecular weight:286.366MMV03
CAS:MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.Formula:C19H14N4OSColor and Shape:SolidMolecular weight:346.406Noracronycine
CAS:Noracronycine is an alkaloid originally isolated from G. pentaphylla, known for its antimalarial activity. It is effective against P. yoelii at a concentration of 10 μg/mL.Formula:C19H17NO3Molecular weight:307.34SPB07935
CAS:SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.Formula:C22H15N5O4S2Color and Shape:SolidMolecular weight:477.516LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formula:C22H15N7Color and Shape:SolidMolecular weight:377.40SLU-10906
CAS:SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.Formula:C22H21BFN5O2Color and Shape:SolidMolecular weight:417.244Ferrocene
CAS:Ferrocene, a crucial structural core in bioorganometallic chemistry, is renowned for its intrinsic stability, excellent oxygen reduction capabilities, and low toxicity. It also exhibits antimalarial and anticancer properties.Formula:C10H10FeColor and Shape:SolidMolecular weight:186.03Etofamide
CAS:Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.Formula:C19H20Cl2N2O5Color and Shape:SolidMolecular weight:427.28
