Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 704 products of "Antiparasitics"
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Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44(+)-Isopulegol
CAS:<p>(+)-Isopulegol is a monoterpenoid from Mentha canadensis L.</p>Formula:C10H18OPurity:99.885%Color and Shape:SolidMolecular weight:154.25Farnesal
CAS:Controlled Product<p>Applications Farnesal is a reagent in the synthesis of farnesylpyrophosphate analogues which acts as bisubstrate inhibitors of protein farnesyltransferase and has antiparasitics properties.<br>References Duez, S. et al.: Bioorg. Med. Chem., 18, 543 (2010);<br></p>Formula:C15H24OColor and Shape:NeatMolecular weight:220.35Amopyroquine
CAS:Controlled Product<p>Applications Antimalarial agent. The compound showed antimalarial activity similar to that of Chloroquine.<br>References Desjardins, R., et al.: Antimicrob. Agents Chemother., 16, 710 (1979), McKie, J., et al.: J. Med. Chem., 41, 1367 (1998), Gozalbes, R., et al.: J. Pharm. Pharmacol., 52, 111 (1999), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 1293 (2005),<br></p>Formula:C20H20ClN3OColor and Shape:NeatMolecular weight:353.855-Amino-1-(1,1-dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-pyrazole-4-carbonitrile
Controlled Product<p>Applications 5-Amino-1-(1,1-dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-pyrazole-4-carbonitrile is an derivative in the synthesis of small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by toxoplasma gondii.<br>References Lourido, S., et al.: J. Med. Chem., 56, 3068 (2013);<br></p>Formula:C17H22N4Color and Shape:NeatMolecular weight:282.383Methyl 2-((1R,3R,4''S,5R,5'S,7R)-Dispiro[adamantane-2,3'-[1,2,4]trioxolane-5',1''-cyclohexan]-4''-yl)acetate
CAS:Controlled Product<p>Applications Methyl 2-((1R,3R,4''S,5R,5'S,7R)-dispiro[adamantane-2,3'-[1,2,4]trioxolane-5',1''-cyclohexan]-4''-yl)acetate is an intermediate for the synthesis of Arterolane p-Toluenesulfonic Acid (A614161), which is an antimalaria agent.<br>References Valecha, N., et al.: Clin Infect Dis. 55, 663 (2012); Patil, C. Y., et al.: Ann Med Health Sci Res. 4, 466 (2014)<br></p>Formula:C19H28O5Color and Shape:NeatMolecular weight:336.421-Methyl-4-nitro-1H-imidazole-5-carboxamide
CAS:Controlled Product<p>Applications A substituted imidazolothiazole derivative as possible antiparasitic agents.<br>References Sarasin, J., et al.: Helv. Chim. Acta, 7, 713 (1924),<br></p>Formula:C5H6N4O3Color and Shape:NeatMolecular weight:170.13(±)-2-(2,4-Dichlorophenyl)-2-hydroxyethylamine
CAS:Controlled Product<p>Applications (±)-2-(2,4-Dichlorophenyl)-2-hydroxyethylamine is an intermediate in the synthesis of Aminoazabenzimidazoles, a novel class of orally active antimalarial agent.<br>References Hameed, P., et al.: J. Med. Chem., 57, 5702 (2014);<br></p>Formula:C8H9Cl2NOColor and Shape:NeatMolecular weight:206.07cis-Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetic Acid
CAS:Controlled Product<p>Applications cis-Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetic Acid is an intermediate for the synthesis of Arterolane p-Toluenesulfonic Acid (A614161), which is an antimalaria agent.<br>References Valecha, N., et al.: Clin Infect Dis. 55, 663 (2012); Patil, C. Y., et al.: Ann Med Health Sci Res. 4, 466 (2014)<br></p>Formula:C18H26O5Color and Shape:NeatMolecular weight:322.4N-(2-Indol-3-ylethyl)-succinamic Acid Methyl Ester
CAS:Controlled Product<p>Applications N-(2-Indol-3-ylethyl)-succinamic Acid Methyl Ester is an intermediate in the synthesis of Canthin-6-one (C175635), which is used as an anticancer agent compromising cancer cells showing multi-drug resistance. Also used in the synthesis of β-carbolinium compounds as antimalarial agents.<br>References Murakami, C. et al.: Bioorg. Med. Chem., 12, 4963 (2004); Takasu, K. et al.: Chem. Pharm. Bull., 53, 653 (2005);<br></p>Formula:C8H12N3O5PColor and Shape:NeatMolecular weight:261.172(3-Benzyloxypropyl)triphenylphosphonium Bromide
CAS:Controlled ProductFormula:C28H28BrOPColor and Shape:NeatMolecular weight:491.44''-Keto-5-O-[(2-propenyloxy)carbonyl]-Abamectin
CAS:Controlled Product<p>Applications 4''-Keto-5-O-[(2-propenyloxy)carbonyl]-Abamectin is a derivative of Abamectin (A107000), a mixture of avermectins, containing at least 80% of avermectin B1a (C48H72O14) and not more than 20% of avermectin B1b (C47H70O14). Used as acaricide, insecticide, Cannabis pesticide detection.<br>References Wang, S., et al.: Prog. Clin. Biol. Res., 97, 373 (1982); Greenblatt, J.A., et al.: J. Agric. Entomol., 3, 233 (1986); Drexler, G., et al.: Eur. J. Pharmacol., 99, 269 (1984);<br></p>Formula:C52H74O16Color and Shape:NeatMolecular weight:955.1344''-Amino-5-O-[(2-propenyloxy)carbonyl] O’-TMS Abamectin
Formula:C55H85NO15SiPurity:~90%Color and Shape:NeatMolecular weight:1028.351,2-Dihydro-5-methoxy-3H-1,2,4-triazol-3-one
CAS:Controlled ProductFormula:C3H5N3O2Color and Shape:NeatMolecular weight:115.097-Bromo-6-chloro-4(3H)-quinazolinone
CAS:Controlled ProductFormula:C8H4BrClN2OColor and Shape:NeatMolecular weight:259.49N-(Glycoloyloxy)-succinimide
CAS:Controlled ProductFormula:C6H7NO5Color and Shape:NeatMolecular weight:173.12(3R-cis)-Dihydro-3-hydroxy-4-(phenylmethoxy)-2(3H)-furanone
CAS:Controlled ProductFormula:C11H12O4Color and Shape:NeatMolecular weight:208.213-(3,4-Dichlorophenyl)triaz-2-ene-1-carbonitrile Potassium Salt
Controlled ProductFormula:C7H3Cl2KN4Color and Shape:YellowMolecular weight:253.13N-[[[2-Nitro-5-(propylthio)phenyl]amino]thioxomethyl]carbamic Acid Methyl Ester
CAS:Controlled Product<p>Applications N-[[[2-Nitro-5-(propylthio)phenyl]amino]thioxomethyl]carbamic Acid Methyl Ester is an intermediate in the synthesis of Netobimin (N390900), a phenylguanidine anthelmintic agent.<br>References Hernandez-Luiz, F., et al.: Bioorg. Med. Chem. Lett., 6, 2231 (1996);<br></p>Formula:C12H15N3O4S2Color and Shape:NeatMolecular weight:329.4(6R,13S,25R)-5-O-Demethyl-28-deoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl] Milbemycin B
CAS:Controlled Product<p>Applications (6R,13S,25R)-5-O-Demethyl-28-deoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl] Milbemycin B is an intermediate used in the synthesis of Milbemycin D (M344290), which is a macrocyclic lactones that can be used as a nematocide and insecticide.<br>References Arena, J. P., et al.: J. Parasitol 81, 286 (1995); Takiguchi, Y., et al.: J. Antibiot 36, 502 (1983)<br></p>Formula:C40H64O8SiColor and Shape:NeatMolecular weight:701.02(2E)-5-Hydroxy-2-pentenoic Acid Methyl Ester
CAS:Controlled ProductFormula:C6H10O3Color and Shape:NeatMolecular weight:130.14(2R,3R)-Benzhydryl 2,3-Bis(benzyloxy)-4-((bis(benzyloxy)phosphoryl)oxy)butanoate
Controlled Product<p>Applications (2R,3R)-Benzhydryl 2,3-Bis(benzyloxy)-4-((bis(benzyloxy)phosphoryl)oxy)butanoate is an intermediate in synthesizing 4-Phospho D-Erythronate (P355000), which is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme.<br>References Tanaka, N., et al.: J. Mol. Biol., 324, 519 (2002); Fitzpatrick, T., et al.: Biochem. J., 407, 1 (2007); Kalliri, E., et al.: J. Bacteriol., 190, 3793 (2008)<br></p>Formula:C45H43O8PColor and Shape:NeatMolecular weight:742.7922-(4-((5,6-Dimethoxyquinolin-8-yl)amino)pentyl)isoindoline-1,3-dione
CAS:Controlled ProductFormula:C24H25N3O4Color and Shape:NeatMolecular weight:218.769Toltrazuril
CAS:<p>Toltrazuril is an anticoccidial agent with action on protozoal parasites by disrupting their intracellular development and is used for treating coccidiosis in livestock and poultry.</p>Formula:C18H14F3N3O4SPurity:Min. 95%Color and Shape:White PowderMolecular weight:425.38 g/molTinidazole
CAS:<p>Tinidazole is a nitroimidazole antibiotic with action on DNA synthesis disruption in anaerobic bacteria and protozoa and is used for treating infections like giardiasis, amebiasis, and trichomoniasis.</p>Formula:C8H13N3O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:247.27 g/molBithionol Disodium Salt
CAS:Formula:C12H4Cl4Na2O2SPurity:>98.0%(T)(HPLC)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:400.00Thiabendazole
CAS:<p>Thiabendazole is a benzimidazole anthelmintic with action on parasitic worms by inhibiting energy metabolism and is used for treating infections like threadworm and roundworm.</p>Formula:C10H7N3SPurity:Min. 95%Color and Shape:PowderMolecular weight:201.25 g/molPraziquantel D11
CAS:<p>Praziquantel D11 is the deuterium labeled Praziquantel, and is an agent of anthelmintic.</p>Formula:C19H24N2O2Purity:98%Color and Shape:SolidMolecular weight:323.47Symetine dihydrochloride
CAS:<p>Symetine dihydrochloride (L 16726 dihydrochloride) is the bis-hydrochloride form of Symetine. It exhibits antiprotozoal activity against Entamoeba histolytica and can ameliorate amoebic liver abscesses in guinea pigs.</p>Formula:C30H50Cl2N2O2Color and Shape:SolidMolecular weight:541.64Monodesethyl Quinacrine, Dihydrochloride
CAS:Controlled ProductFormula:C21H26ClN3O·2ClHColor and Shape:NeatMolecular weight:444.836-(Aminocarbonyl)pyridine-3-boronic Acid
CAS:Controlled Product<p>Applications 6-(Aminocarbonyl)pyridine-3-boronic Acid is a reagent in the identification of highly potent compounds against human malaria parasite Plasmodium falciparum.<br>References Le Manach, C., et al.: J. Med. Chem., 59, 9890-9905 (2016);<br></p>Formula:C6H7BN2O3Color and Shape:NeatMolecular weight:165.941-Undecyne
CAS:Controlled Product<p>Applications 1-Undecyne is a reagent used in organic chemical synthesis. Used in the synthesis of antimalarial and antitrypanosomal agents.<br>References Wube, A. et al.: Molecule, 19, 14204 (2014); Sun, S. et al.: Chin. Chem. Polym. Sci., 33, 184 (2015);<br></p>Formula:C11H20Color and Shape:NeatMolecular weight:152.28(2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate
Controlled Product<p>Applications (2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate is an intermediate in synthesizing 4-Phospho D-Erythronate (P355000), which is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme.<br>References Tanaka, N., et al.: J. Mol. Biol., 324, 519 (2002); Fitzpatrick, T., et al.: Biochem. J., 407, 1 (2007); Kalliri, E., et al.: J. Bacteriol., 190, 3793 (2008)<br></p>Formula:C31H30O5Color and Shape:NeatMolecular weight:482.567(R)-2-Methyl-1-tosylaziridine
CAS:Controlled Product<p>Applications (R)-2-Methyl-1-tosylaziridine can be used to synthesize tetrahydropyridines, morpholines, chiral β-and γ-amino ethers, and (ent)-korupensamine D. Korupensamine D is a natural product that exhibits antimalarial properties.<br>References Ghorai, M. K., et al.: J. Org. Chem. 77, 3740 (2012); Pattenden, L. C., et al.: Org. Lett. 8, 3089 (2006); Hallock, Y. F., et al.: J. Nat. Prod. 60, 677 (1997)<br></p>Formula:C10H13NO2SColor and Shape:NeatMolecular weight:211.281-[4-(1H-Indol-3-Yl)Piperidino]Ethan-1-One
CAS:Controlled Product<p>Applications 1-[4-(1h-Indol-3-Yl)Piperidino]Ethan-1-One (cas# 30030-83-2) is a useful research chemical.<br></p>Formula:C15H18N2OColor and Shape:NeatMolecular weight:242.31Artemisic Acid
CAS:<p>Applications Artemisic Acid is a derivative of Artemisinin (A777500), an antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.<br>References Klayman, D.L., et al.: Science, 228, 1049 (1985), Price, R.N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000), Meshnick, S.R., et al.: Int. J., Parasitol., 32, 1655 (2002),<br></p>Formula:C15H22O2Color and Shape:NeatMolecular weight:234.33α-Hydroxy-3-phenoxybenzeneacetonitrile (>90%)
CAS:Controlled ProductFormula:C14H11NO2Purity:>90%Color and Shape:NeatMolecular weight:225.24(E)-4-Hydroxycrotonoic Acid Ethyl Ester (~85%)
CAS:Controlled Product<p>Stability No Date Available<br>Applications (E)-4-Hydroxycrotonoic Acid Ethyl Ester is an intermediate in the preparation of unusual amino acids that are potential Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors.<br>References Breuning, A., et al.: J. Med. Chem., 53, 1951 (2010);<br></p>Formula:C6H10O3Purity:~85%Color and Shape:NeatMolecular weight:130.142-Acetamido-2-deoxy-4-O-(β-D-galactofuranosyl)-α,β-D-glucopyranose
CAS:Controlled Product<p>Applications Synthetic galactofuranose-containing oligosaccharides could be useful for the identification of strains of T. cruzi as well as for studies on the inhibition of the biosynthesis of these unique O-linked chains.<br>References Gallo-Rodriguez, C., et al.: J. Org. Chem., 61, 1886 (1996)<br></p>Formula:C14H25NO11Color and Shape:NeatMolecular weight:383.348N-Decylaminoethanol
CAS:Controlled Product<p>Applications Used in the antileishmanial activity of lipidic amino alcohols.<br>References Coimbra, E.: Chem. Biol. Drug Des. 75, 233 (2010).<br></p>Formula:C12H27NOColor and Shape:NeatMolecular weight:201.357-Amino-1,5-dihydro-5-imino-2,8-quinolinedione Hydrochloride
CAS:Controlled Product<p>Applications 7-Amino-1,5-dihydro-5-imino-2,8-quinolinedione is a quinoline derivative. The principle use of Quinoline is the preparation of 8-hydroxyquinoline (H953265), a versatile chelating agent and precursor to certain antimalarial and anticancer drugs.<br>References Pettit, G.R., et al.: J. Org. Chem., 33, 1089 (1968);<br></p>Formula:C9H8ClN3O2Color and Shape:NeatMolecular weight:225.633,6-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine
CAS:Controlled ProductFormula:C28H38O19Color and Shape:NeatMolecular weight:678.59p-Cyanoacetophenone
CAS:Controlled Product<p>Applications Used in the preparation of antimalarial isonitriles.<br>References Singh, C. et al.; Bioorgan. Med. Chem. Lett. 12, 2277 (2002)<br></p>Formula:C9H7NOColor and Shape:NeatMolecular weight:145.16Methyl 1-[[2-N-(5-Nitrothiazolyl)carboxamido]phenyl]-2,3,4- tri-O-acetyl-β-D-glucopyranuronate
CAS:Controlled Product<p>Applications An intermediate in the synthesis of the metabolite of Nitazoxanide.<br>References Honma, K., et al.: Chem. Pharm. Bull., 24, 394 (1976), Dubreuil, L., et al.: Antimicrob. Agents Chemother., 40, 2266 (1996), Stockis, A., et al.: Int. J. Clin. Pharmacol. Ther., 34, 349 (1996),<br></p>Formula:C23H23N3O13SColor and Shape:YellowMolecular weight:581.51Canthin-6-one
CAS:Controlled Product<p>Applications Canthin-6-one is used as an anticancer agent compromising cancer cells showing multi-drug resistance. Also used in the synthesis of β-carbolinium compounds as antimalarial agents.<br>References Murakami, C. et al.: Bioorg. Med. Chem., 12, 4963 (2004); Takasu, K. et al.: Chem. Pharm. Bull., 53, 653 (2005);<br></p>Formula:C14H8N2OColor and Shape:NeatMolecular weight:220.23α-(3,4-Diethoxyphenyl)-6,7-diethoxy-1-isoquinolinemethanol
CAS:Controlled Product<p>Applications α-(3,4-Diethoxyphenyl)-6,7-diethoxy-1-isoquinolinemethanol is an intermediate in synthesizing Ethaverine (E676700), which is an analogue of Papaverine (P190500), an antispasmodic. An isoquinoline derivative with the potential for antimicrobial, antimalarial and cytotoxic antiviral agents.<br>References Kaplan, D., et al.: Biochem. J., 201, 605 (1982), Hifnawy, M.S., et al.: Anal. Profiles Drug Subs., 17, 367 (1988); Iwasa, K. et al.: Bioorg. Med. Chem., 9, 2871 (2001);<br></p>Formula:C24H29NO5Color and Shape:NeatMolecular weight:411.491,2-Diamino-2-methyl Propane
CAS:Controlled Product<p>Applications 1,2-Diamino-2-methyl Propane is a reactant used in the preparation of neocryptolepine analogs with antimalarial activity.<br>References Shaban, E., et. al.: Heterocycles, 89, 1055 (2014)<br></p>Formula:C4H12N2Color and Shape:NeatMolecular weight:88.15Ethaverine
CAS:<p>Applications Ethaverine is an analogue of Papaverine (P190500), an antispasmodic. An isoquinoline derivative with the potential for antimicrobial, antimalarial and cytotoxic antiviral agents.<br>References Kaplan, D., et al.: Biochem. J., 201, 605 (1982), Hifnawy, M.S., et al.: Anal. Profiles Drug Subs., 17, 367 (1988); Iwasa, K. et al.: Bioorg. Med. Chem., 9, 2871 (2001);<br></p>Formula:C24H29NO4Color and Shape:NeatMolecular weight:395.49(R)-1-Boc-3-hydroxymethylpiperazine
CAS:Controlled ProductFormula:C10H20N2O3Color and Shape:NeatMolecular weight:216.28
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