Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 700 products of "Antiparasitics"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
GNF179
CAS:GNF179 is an optimized 8,8-dimethyl IP analog.Formula:C22H23ClFN5OPurity:98.9%Color and Shape:SolidMolecular weight:427.9Ref: TM-T15409
1mg109.00€2mg158.00€5mg260.00€10mg430.00€25mg710.00€50mg973.00€100mg1,333.00€1mL*10mM (DMSO)286.00€Clorsulon
CAS:Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.Formula:C8H8Cl3N3O4S2Purity:99.66% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:380.66Oxantel Pamoate
CAS:Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.Formula:C36H32N2O7Purity:99% - 99.89%Color and Shape:SolidMolecular weight:604.65SpdSyn binder-1
CAS:SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.Formula:C21H22N4OPurity:99.5%Color and Shape:SolidMolecular weight:346.43ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Formula:C17H13Cl2N3O4SPurity:99.87%Color and Shape:SolidMolecular weight:426.27Ref: TM-T64320
1mg109.00€5mg260.00€10mg409.00€25mg677.00€50mg954.00€100mg1,288.00€200mg1,728.00€1mL*10mM (DMSO)285.00€Antiparasitic agent-20
Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T.Purity:98%Color and Shape:Odour SolidAntitrypanosomal agent 12
Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.Formula:C49H77N2NaO10SPurity:98%Color and Shape:SolidMolecular weight:909.2DXR-IN-1
DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). It exhibits high selectivity for DXR of Plasmodium falciparum with an IC50 of 0.030 μM. DXR-IN-1 impedes the growth of Plasmodium by binding to the active site of DXR and inhibiting its catalytic activity.Formula:C19H24NO5PMolecular weight:377.13921TSO-13
TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.Formula:C32H36N4O4S2Color and Shape:SolidMolecular weight:604.78Cysteine protease inhibitor-3
Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM),Formula:C26H22ClF2N3OPurity:98%Color and Shape:SolidMolecular weight:465.92NMT-IN-3
NMT-IN-3 is an inhibitor of N-myristoyltransferase (NMT), displaying an IC50 of 38 mM against Plasmodium vivax NMT.Formula:C26H32N6O4Molecular weight:492.2485Diarctigenin
Diarctigenin is a selective inhibitor of Leishmania major dihydrofolate reductase-thymidylate synthase (LmDHFR-TS), and it is applicable in the study of tropical diseases.Formula:C42H46O12Molecular weight:742.29893Antileishmanial agent-20
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.Formula:C15H16N4O3Purity:98%Color and Shape:SolidMolecular weight:300.31Antiparasitic agent-17
Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-Formula:C32H30N2O4Purity:98%Color and Shape:SolidMolecular weight:506.59Nanaomycin A
CAS:Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).Formula:C16H14O6Purity:98%Color and Shape:SolidMolecular weight:302.28Doxycycline monohydrate
CAS:Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)Formula:C22H26N2O9Purity:99.97%Color and Shape:SolidMolecular weight:462.4Cletoquine
CAS:Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.Formula:C16H22ClN3OPurity:99.95% - 99.98%Color and Shape:SolidMolecular weight:307.82Antileishmanial agent-25
Antileishmanial agent-25 (compound 24) exhibits selective activity against intracellular amastigotes, demonstrating an inhibitory concentration (IC50) of 6.63Purity:98%Color and Shape:Odour SolidCardol triene
CAS:Cardol triene, Phenolic compound, competitively inhibits mushroom tyrosinase (IC50=22.5 μM) and S. mansoni, for dibenzoxazine synthesis.Formula:C21H30O2Color and Shape:SolidMolecular weight:314.46Antiparasitic agent-26
Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).
Color and Shape:Odour SolidSulfadiazine
CAS:Sulfadiazine, a short-acting sulfonamide, blocks bacterial folic acid synthesis; used with pyrimethamine to treat toxoplasmosis in AIDS, newborns.Formula:C10H10N4O2SPurity:99.32%Color and Shape:White To Slightly Yellow Crystalline PowderMolecular weight:250.28Antitrypanosomal agent 23
Antitrypanosomal agent 23 is an antiparasitic compound effective against intracellular amastigotes of Trypanosoma cruzi in LLC-MK2 and C2C12 cells, demonstrating activity with IC50 values of 0.10 and 0.11 μM, respectively. It also acts as a weak inhibitor of recombinant Trypanosoma cruzi sialyltransferase (TcTS) with an IC50 of 1.1 mM.Formula:C14H16N4O7Color and Shape:SolidMolecular weight:352.1019Cinchonidine
CAS:Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.Formula:C19H22N2OPurity:94.96% - 99.87%Color and Shape:White PowderMolecular weight:294.39Antimalarial agent 28
Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P.
Formula:C27H25ClFN3O2Purity:98%Color and Shape:SolidMolecular weight:477.96Antimalarial agent 31
Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].Formula:C36H47N3O4Purity:98%Color and Shape:SolidMolecular weight:585.78Norselic acid B
CAS:Norselic acid B is a naturally occurring compound that can be isolated from the sponge Crella sp. collected in Antarctica. It demonstrates activity against Leishmania parasites.Formula:C29H44O4Color and Shape:SolidMolecular weight:456.657Urethane
CAS:Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.Formula:C3H7NO2Purity:99.01%Color and Shape:SoildMolecular weight:89.09Antiproliferative agent-56
Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.Color and Shape:Odour SolidAAP4
AAP4 is a potent inhibitor of OfChi-h and OfHex1, exhibiting Ki values of 29.3 nM and 4.9 μM, respectively. It also demonstrates insecticidal activity against the lepidopteran pest Ostrinia furnacalis.Formula:C21H23BrClN7Color and Shape:SolidMolecular weight:488.8114-(Trifluoromethyl)nicotinic acid
CAS:Compound FL0181, with CAS No. 158063-66-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0181 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C7H4F3NO2Purity:98%Molecular weight:191.11Nitroxynil
CAS:Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.Formula:C7H3IN2O3Purity:99.76%Color and Shape:SolidMolecular weight:290.01Antimalarial agent 27
Antimalarial agent 27 (compound 11a) potently inhibits P.Formula:C10H11NNaO5PPurity:98%Color and Shape:SolidMolecular weight:279.16CpNMT-IN-1
CpNMT-IN-1 (Compound 11e) is an inhibitor of N-myristoyltransferase (CpNMT) with an IC50 value of 2.5 μM. It also inhibits the growth of microsporidia, demonstrating an EC50 value of 6.9 μM.Formula:C25H25ClN4O4SColor and Shape:SolidMolecular weight:513.008LASSBio-1985
LASSBio-1985 is an inhibitor of NHLd (nucleoside hydrolase of Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. It exhibits selective toxicity against Leishmania parasites without affecting mammals, showing potential for research in infectious disease treatment.Formula:C18H22N2O7Color and Shape:SolidMolecular weight:378.38Antimalarial agent 43
Antimalarial agent 43 (compound 16c) is an antimalarial compound that exhibits an IC50 value of 0.0151 μM against the 3D7 strain.Color and Shape:Odour SolidEmoquine-1
Emoquine-1 is a potent orally active antimalarial agent effective against various drug-resistant Plasmodium strains, including artemisinin-resistant dormant parasites. It demonstrates efficacy against proliferative malignant Plasmodium with an IC50 value ranging from 20 to 55 nM. Emoquine-1 holds potential for treating Plasmodium strains resistant to artemisinin combination therapy (ACT), with the capability to eradicate persistent parasites.Formula:C30H28ClN3O6Color and Shape:SolidMolecular weight:562.013Sarolaner
CAS:Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).Formula:C23H18Cl2F4N2O5SPurity:99.54% - 99.65%Color and Shape:SolidMolecular weight:581.36Antimalarial agent 47
Antimalarial agent 47 (compound F14) is a chemical compound effective against Plasmodium falciparum, specifically targeting the W2 strain with an IC50 value of 235 nM.Formula:C16H14ClF2NOColor and Shape:SolidMolecular weight:309.74Azlocillin sodium salt
CAS:Azlocillin sodium, an acylampicillin, is a broad-spectrum antibioticsFormula:C20H22N5NaO6SPurity:97.63% - 98.302%Color and Shape:SolidMolecular weight:483.47Ile-AMS TFA
Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.Formula:C18H27F3N8O8SColor and Shape:SolidMolecular weight:572.528304-vs
8304-vs is a macrocyclic anti-Plasmodial compound that irreversibly binds to and inhibits the Plasmodium proteasome, effectively halting the growth ofFormula:C35H53N5O8SPurity:98%Color and Shape:SolidMolecular weight:703.89Antileishmanial agent-26
Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with activity against *Leishmania donovani*, exhibiting an IC50 value of 5.67 μM and a CC50 value of 3.79 μM in THP-1 cells. This compound is applicable for research in tropical diseases.Formula:C23H27FN4O2Molecular weight:410.2118Amprolium
CAS:Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.Formula:C14H19N4·ClPurity:98%Color and Shape:SolidMolecular weight:278.79Febrifugine dihydrochloride
CAS:Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatoryFormula:C16H21Cl2N3O3Purity:98.27% - 99.85%Color and Shape:SolidMolecular weight:374.26Dixanthogen
CAS:Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.Formula:C6H10O2S4Purity:95% - 98%Color and Shape:SolidMolecular weight:242.4Alkaline tryptase-IN-1
Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.Formula:C29H33BrN2O2SColor and Shape:SolidMolecular weight:553.554-(2-Aminoethyl)amino-7-chloroquinoline
CAS:4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study ofFormula:C11H12ClN3Purity:98.53%Color and Shape:SolidMolecular weight:221.69β-Hederin
CAS:β-Hederin has antileishmanial activity. β-Hederin has apoptotic effect on cancer cells, it could be a promising candidate for chemotherapy of breast cancer.Formula:C41H66O11Purity:98%Color and Shape:SolidMolecular weight:734.96Antileishmanial agent-24
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM againstFormula:C34H29Cl4N3O2Purity:98%Color and Shape:SolidMolecular weight:653.42Antitrypanosomal agent 17
Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].Purity:98%Color and Shape:Odour Solid
