Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 704 products of "Antiparasitics"
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CpCDPK1/TgCDPK1-IN-2
CAS:<p>CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can</p>Formula:C20H21N5OPurity:99.12%Color and Shape:SoildMolecular weight:347.41PfSUB1-IN-1
<p>PfSUB1-IN-1 (compound 4c) is an inhibitor of Plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1), exhibiting potent activity with an IC50 value of 15 nM. PfSUB1 is a key target in antimalarial research. PfSUB1-IN-1 demonstrates a 13-fold greater inhibitory effect on the growth of transgenic Plasmodium falciparum strains (expressing lower levels of PfSUB1 compared to the wild-type) than on wild-type parasite strains.</p>Color and Shape:Odour SolidAntileishmanial agent-30
<p>Compound 17k, also known as Antileishmanial agent-30, effectively inhibits Leishmania with an IC50 of 0.2 μM for L. donovani. It exhibits a CC50 of >100 μM and an SI of >500, indicating significant selectivity and potency.</p>Formula:C23H21N5O2Color and Shape:SolidMolecular weight:399.453-Deoxyaphidicolin
CAS:<p>3-Deoxyaphidicolin is a phytotoxin that inhibits root growth in lettuce seedlings. Additionally, 3-Deoxyaphidicolin exhibits inhibitory activity against the protozoan parasites Leishmania major and Leishmania braziliensis.</p>Formula:C20H34O3Color and Shape:SolidMolecular weight:322.48Amitraz
CAS:<p>Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.</p>Formula:C19H23N3Purity:99.88%Color and Shape:White/Pale Yellow Crystalline SolidMolecular weight:293.41Dodecamethylpentasiloxane
CAS:<p>Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.</p>Formula:C12H36O4Si5Purity:97.43%Color and Shape:SolidMolecular weight:384.84LL-37 FK-13 TFA
<p>LL-37 FK-13 TFA, the TFA salt form of LL-37 FK-13, is an antimicrobial agent that inhibits Trichomonas vaginalis. It exhibits minimal hemolytic effects on human red blood cells and shows slight cytotoxicity towards human fibroblasts.</p>Color and Shape:Odour SolidMMV1634566
<p>MMV1634566 is an effective antimalarial agent that can inhibit Plasmodium falciparum and exhibits cytotoxicity.</p>Color and Shape:Odour SolidAntimalarial agent 42
<p>Compound 42 (Compound 2), an antimalarial agent, effectively inhibits Plasmodium falciparum during the asexual blood stages (IC 50 <0.5μM) and gametocytes (IC 50 is 0.14 μM).</p>Formula:C24H42N2Color and Shape:SolidMolecular weight:358.6AChE-IN-66
<p>Nematicidal Agent 1 is an effective nematicide that binds to the pocket of acetylcholinesterase (AChE).</p>Color and Shape:Odour SolidBitoscanate
CAS:<p>Bitoscanate (PDITC) is used in the treatment of hookworms.</p>Formula:C8H4N2S2Purity:98.32%Color and Shape:Colorless Needles Bitoscanate Is An Odorless Colorless Crystals Melting Point 132°CMolecular weight:192.26SpdSyn binder-1
CAS:<p>SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.</p>Formula:C21H22N4OPurity:99.5%Color and Shape:SolidMolecular weight:346.43Se2h
<p>Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.</p>Formula:C12H13ClN4O2SeColor and Shape:SolidMolecular weight:359.67JC-229
CAS:<p>JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).</p>Formula:C20H14Cl4N2O3SPurity:97.14%Color and Shape:SolidMolecular weight:504.21Insecticidal agent 24
<p>Insecticidal agent 24 is an orally active pyridinyl spiroindoline lead compound. It demonstrates antimalarial activity with Pf NF54IC50 of 0.08 μM. Insecticidal agent 24 also inhibits hERG activity with an IC50 of 6.5 μM. In a humanized immunodeficient NSG mouse model of malaria infection, it effectively reduces parasitemia.</p>Formula:C26H29N3O2Color and Shape:SolidMolecular weight:415.22598pCDPK1/TgCDPK1-IN-3
CAS:<p>CpCDPK1/TgCDPK1-IN-3 inhibits Cp/TgCDPK1; IC50: 0.003/0.0036 µM. It's used to research Toxoplasma, Cryptosporidium diseases.</p>Formula:C17H18N6Purity:99.63%Color and Shape:SoildMolecular weight:306.36ML251
CAS:<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formula:C17H13Cl2N3O4SPurity:99.87%Color and Shape:SolidMolecular weight:426.271,2-Dimethyl-1H-benzo[d]imidazole
CAS:<p>1,2-Dimethyl-1H-benzo[d]imidazole has antibacterial activity against Entamoeba histolytica and Giardia lamblia,</p>Formula:C9H10N2Purity:99.86%Color and Shape:SolidMolecular weight:146.19Antimalarial agent 13
CAS:<p>Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent.</p>Formula:C19H15ClN4OPurity:99.15%Color and Shape:SolidMolecular weight:350.8N-Methyl-1,3-benzoxazol-2-amine
CAS:<p>N-Methyl-1,3-benzoxazol-2-amine, with CAS No. 19776-98-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-Methyl-1,3-benzoxazol-2-amine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C8H8N2OColor and Shape:SoildMolecular weight:148.1616Eflornithine
CAS:<p>Eflornithine blocks ornithine decarboxylase, treating African trypanosomiasis and female facial hair.</p>Formula:C6H12F2N2O2Purity:99.44% - 99.84%Color and Shape:SolidMolecular weight:182.17Antileishmanial agent-33
<p>Antileishmanial agent-33 (4e) is a hybrid compound of grandisin and machilin G, demonstrating moderate activity against promastigotes with an IC50 of 38.1 μM. In studies of cutaneous leishmaniasis (CL), Antileishmanial agent-33 (4e) has shown potential as an antileishmanial agent.</p>Color and Shape:Odour SolidACT-451840
CAS:<p>ACT-451840 eliminates both sensitive and resistant strains of Plasmodium falciparum and has the advantages of oral, potency, low toxicity, rapid.</p>Formula:C47H54N6O3Purity:96.07%Color and Shape:SolidMolecular weight:750.97Biotin-PEG3-Mal
CAS:<p>Biotin-PEG3-Mal (Biotin-PEG3-NH-Mal) is a biotin-labeled PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules.</p>Formula:C25H39N5O8SPurity:99.5%Color and Shape:SolidMolecular weight:569.67Proteasome-IN-6
<p>Proteasome-IN-6 (Compound J-80) inhibits the β5 catalytic subunit of the Trypanosoma brucei 20S proteasome, effectively blocking T. b. brucei, T. b. gambiense, and T. b. rhodesiense with EC50 values of 157 nM, 220 nM, and 156 nM, respectively. Additionally, Proteasome-IN-6 has demonstrated antitrypanosomal activity in a mouse model.</p>Formula:C35H45F3N4O6Color and Shape:SolidMolecular weight:674.75Pyronaridine tetraphosphate
CAS:<p>Pyronaridine tetraphosphate is a DNA topoisomerase 2 inhibitor with antimalarial and antitumor activity for the treatment of P. falciparum infection.</p>Formula:C29H44ClN5O18P4Purity:99.82%Color and Shape:SolidMolecular weight:910.03Nanaomycin A
CAS:<p>Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).</p>Formula:C16H14O6Purity:98%Color and Shape:SolidMolecular weight:302.28WJM280
<p>WJM280 is an orally active antimalarial compound with an EC50 of 0.04 μM against the parasite P. falciparum 3D7.</p>Formula:C22H25F3N2OColor and Shape:SolidMolecular weight:390.44Antimalarial agent 45
<p>Antimalarial agent 45 (compound 8I) is an antimalarial with activity against Plasmodium parasites, exhibiting an IC50 of 0.21 μM. It is used in the study of malaria.</p>Formula:C33H34N4O3Color and Shape:SolidMolecular weight:534.65Mepartricin
CAS:<p>Mepartricin, a polyene macrolide, exhibits both antifungal and antiprotozoal activities and is extensively utilized in studies related to benign prostatic hyperplasia.</p>Color and Shape:SolidSchizophyllan
CAS:<p>Schizophyllan, a member of the β-glucan family, is an extracellular polysaccharide known for its antitumor, antibacterial, and antiparasitic activities.</p>Color and Shape:SolidIle-AMS TFA
<p>Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.</p>Formula:C18H27F3N8O8SColor and Shape:SolidMolecular weight:572.52Cinchonidine
CAS:<p>Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.</p>Formula:C19H22N2OPurity:94.96% - 99.87%Color and Shape:White PowderMolecular weight:294.39Gypsogenic acid
CAS:<p>Gypsogenic acid, a triterpenic acid isolated from Miconia stenostachya, exhibits antibacterial and antitrypanosomal activities. This compound demonstrates minimum inhibitory concentrations (MICs) ranging from 50-200 μg/mL against oral bacterial pathogens including Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus spp., and Streptococcus sobrinus. Additionally, gypsogenic acid can induce the lysis of Trypanosoma cruzi in isolated mouse blood, with an IC50 value of 56.6 μM.</p>Formula:C30H46O5Color and Shape:SolidMolecular weight:486.68Cletoquine
CAS:<p>Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.</p>Formula:C16H22ClN3OPurity:99.95% - 99.98%Color and Shape:SolidMolecular weight:307.82Antitrypanosomal agent 15
<p>Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4</p>Formula:C21H19FN4O4Purity:98%Color and Shape:SolidMolecular weight:410.4Human α-defensin 5
<p>Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-</p>Formula:C144H238N50O45S6Purity:98%Color and Shape:SolidMolecular weight:3582.13Urethane
CAS:<p>Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.</p>Formula:C3H7NO2Purity:99.01%Color and Shape:SoildMolecular weight:89.09Antiparasitic agent-25
<p>Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic compound. It inhibits the invasion and replication capabilities of parasites and has an irreversible effect on Toxoplasma gondii. The agent significantly reduces the replication rate of Toxoplasma gondii, with an IC50 value of 6.33 μM, and exhibits low cytotoxicity, having a CC50 value of 285 μM.</p>Color and Shape:Odour SolidFebrifugine dihydrochloride
CAS:<p>Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory</p>Formula:C16H21Cl2N3O3Purity:98.27% - 99.85%Color and Shape:SolidMolecular weight:374.264-Propylbenzene-1,2-diol
CAS:<p>4-Propylbenzene-1,2-diol exhibits antimalarial activity and can inhibit Plasmodium falciparum,</p>Formula:C9H12O2Purity:98.84%Color and Shape:SolidMolecular weight:152.19Modoflaner
CAS:<p>Modoflaner is an antiparasitic (veterinary use).</p>Formula:C23H10F12IN3O2Purity:98.78%Color and Shape:SolidMolecular weight:715.23Antimalarial agent 49
<p>Antimalarial agent 49 is an oral compound with antimalarial properties. It inhibits the growth of Pf3D7 and PfK1 strains, with IC50 values of 0.84 μM and 0.4 μM, respectively. Additionally, it demonstrates the ability to suppress the liver stage development of P. berghei and can be utilized in malaria infection research.</p>Color and Shape:Odour SolidAntiparasitic agent-24
<p>Antiparasitic agent-24 (Compound 14a) is an antiparasitic compound with EC50 values of 0.005 μM for L. maj, 0.069 μM for L. don, 0.82 μM for T. brucei, and 4.1 μM for T. cruzi.</p>Formula:C23H22ClN7O2SColor and Shape:SolidMolecular weight:495.98CCOE-5
<p>CCOE-5 is a chalcone derivative with antimalarial activity, exhibiting an IC50 of 1.4 μg/mL against P. falciparum (3D7) and an IC50 of less than 5 μg/mL against P. falciparum (INDO). CCOE-5 shows potential for research in the anti-infective domain.</p>Formula:C34H31NO6Color and Shape:SolidMolecular weight:549.61Sarolaner
CAS:<p>Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).</p>Formula:C23H18Cl2F4N2O5SPurity:99.54% - 99.65%Color and Shape:SolidMolecular weight:581.36Dixanthogen
CAS:<p>Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.</p>Formula:C6H10O2S4Purity:95% - 98%Color and Shape:SolidMolecular weight:242.4Azlocillin sodium salt
CAS:<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formula:C20H22N5NaO6SPurity:97.63% - 98.302%Color and Shape:SolidMolecular weight:483.47Arprinocid
CAS:Formula:C12H9ClFN5Purity:>95.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:277.69Albendazole Sulfoxide
CAS:Formula:C12H15N3O3SPurity:>98.0%(N)Color and Shape:White to Light yellow powder to crystalMolecular weight:281.33
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