Fatty Acids

<p>Elaidic acid is a monounsaturated trans-fat and 9-trans isomer of oleic acid, found in hydrogenated oils, affecting human platelet activity.</p>

<p>Palmitoleic acid ((Z)-Hexadec-9-enoic acid) is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.</p>

<p>2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease.</p>

<p>Tridecanedioic acid (Brassilic acid) is an unusual odd-numbered dicarboxylic acid that appears in the urines of children with neonatal adrenoleukodystrophy.</p>

<p>1-Hydroxyoctadecane (OctadecanolOctadecanol) is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids.</p>

<p>Undecanoic acid (Hendecanoic acid) is a monocarboxylic acid with antimycotic property. Undecanoic acid inhibits the production of keratinase, lipase.</p>

<p>Nonanoic acid, a 9-C fatty acid, occurs in pelargonium oil; its esters add flavor; it's an oily, rancid-smelling liquid, insoluble in water.</p>

<p>Methylglutaric acid, a leucine byproduct, is linked to two metabolic disorders, detected in patient urine.</p>

<p>3-Methylbut-2-enoic acid (Senecioic acid) appears in the urine of patients with 3-Methylcrotonic aciduria.</p>

<p>2-Hydroxyhexanoic acid, found in human blood, amniotic fluid, and notably in CSF of Nocardia patients.</p>

<p>(S)-Leucic acid, a leucine metabolite in muscles, enhances muscle mass and recovery. It's a 2-hydroxycarboxylic acid used in bodybuilding.</p>

<p>Hexadecanedioic acid (1,16-Hexadecanedioic acid) is a common saturated fatty acid found in animals, plants and microorganisms. It has antitumor activity.</p>

<p>Tridecanoic acid: 13-carbon, saturated fatty acid in dairy and n-hexadecane biodegradation; phospholipase A2 substrate.</p>

<p>Citraconic acid (2-Methylmaleic Acid) is a dicarboxylic acid consisting of maleic acid having a methyl substituent at the 2-position.</p>

<p>Itaconic acid, a soluble, weak acid found in biofluids and eukaryotic cells, is present in foods like cowpea and butternut squash.</p>

<p>Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ).</p>

<p>Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester)induces the synthesis of proteinase inhibitors in plant leaves.</p>

<p>2-Methylsuccinic acid, a human metabolite, marks ethylmalonic encephalopathy with specific symptoms and genetic traits.</p>

<p>Nervonic acid, enriched in sphingomyelin, may boost brain function and combat demyelination; it's linked to lower obesity risks and altered levels in ALD.</p>

<p>Arachidic acid (Icosanoic Acid) is a saturated fatty acid found naturally in fish and vegetable oils. It can be formed by the hydrogenation of arachidonic acid.</p>

<p>Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) is a nutrition enhancer.</p>

<p>Tricosanoic acid, a very long-chain fatty acid found in blood, urine, membranes, cytoplasm, and adiposomes, may indicate citrus, date, and papaya consumption.</p>

<p>1-Hexadecanol (Hexadecan-1-ol), a fatty alcoholis, is utilized for making other chemicals.</p>

<p>Petroselinic acid (5-Heptadecylene-1-carboxylic acid) is a monounsaturated omega-12 fatty acid found naturally in plant and animal oils and fats.</p>

<p>Applications 1-Hexadecanol, is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions.<br>References Smolinske S. C., et al.: Handbook Food Drug and Cosmetic Exipients, 75 (1992);<br></p>

<p>Applications 2,4-Dimethyl-1H-pyrrole-3-carboxylic Acid Ethyl Ester is used in the preparation of blue pyrrole dyes. 2,4-Dimethyl-1H-pyrrole-3-carboxylic Acid Ethyl Ester is also used as an intermediate in the synthesis of receptor tyrosine kinase (RTK) inhibitors and their metabolites.<br>References Treibs, A. et al.: Lieb. Ann. Chem., 2, 289 (1978); Elsinghorst, P. et al.: J. Lab. Comp. Radiopharm., 52, 360 (2009);<br></p>

<p>Applications Hexadecafluoroheptane, 98% (cas# 335-57-9) is a useful research chemical.<br></p>

<p>Applications cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester-d5 is an isotopic analog of cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester. cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester is an ethyl analog of cis-7,10,13,16-Docosatetraenoic Acid (D494510). cis-7,10,13,16-Docosatetraenoic Acid has been identified as a protein kinase inhibitor, affecting serotonin levels in studies.<br>References Mirnikjoo, B. et al.: J. Biol. Chem., 276, 10888 (2001);<br></p>

<p>Stability Light Sensitive<br>Applications Ethyl Palmitoleate-d5 is the isotope analog of Ethyl Palmitoleate. Ethyl Palmitoleate is used in biological studies for calcium relase-activated calcium channel blockade as a potential tool in antipancreatitis therapy.<br>References Gerasimenko, J.V., et al.: Proc. Natl. Acad. Sci. U.S.A., 110, 13186 (2013)<br></p>

<p>Stability Moisture Sensitive; Store in Freezer, Hygroscopic<br>Applications N-hydroxysuccinimide ester of palmitic acid. Esters of N-hydroxysuccinimide have been used for the preparation of N-acylamino acids, aminoacyl-tRNA, coenzyme A, thioglycolic acid, ceramides, etc.<br>References Lapidot, Y., et al.: J. Lipid Res., 8, 142 (1967); Lapidot, Y., et al.: Biochim. Biophys. Acta, 145, 292 (1967); Al-Arif, A., et al.: J. Lipid Res., 10, 344 (1969); Ong, D.E., and Brady, R.N., J. Lipid Res., 13, 819 (1972)<br></p>

<p>Applications Lauroylcholine Chloride (cas# 25234-60-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Isopropyl Palmitate has been used in the preparation of a pseudolatex-membrane for ketoprofen transdermal drug delivery systems.<br>References Suksaeree, J., et. al.: Ind. Eng. Chem. Res., 52, 15847 (2013)<br></p>

<p>Applications N-Hexadecanol (2,2,3,3...16,16,16-D31, 98%) (cas# 203633-15-2) is a useful research chemical.<br></p>

<p>Applications Used for cyclizations of propynyl compounds: a synthesis of 2,4-imidazolidinediones (hydantoins).<br>References Xie, J., et al.: Bioorg. Med. Chem., 15, 458 (2007),<br></p>

<p>Applications N-Boc-propargylamine is used in the preparation of triazolobenzylidene-thiazolopyrimidines which act as CDC25 phosphatase inhibitors. Also used in the synthesis of β-glucan polysaccharide analogs.<br>References Duval, R. et al.: J. Comb. Chem., 11, 947 (2009); Tanaka, H. et al.: Tetrahedron Lett., 53, 4104 (2012);<br></p>

<p>Applications (9Z)-9-Octadecen-1-ol, is an unsaturated fatty alcohol, that can be used a nonionic surfactant, emulsifier, emollient and thickener in skin creams, lotions and many other cosmetic products.<br>References Linh D.D, et al.: Int. J. Gre. Eng., 8, 748 (2011);<br></p>

<p>Applications n-Hexadecane-d34 is the labeled compound of Hexadecane(H293630). Hexadecane has been used to prepare emulsions in water. It is also used as a substrate for the bacterial production of biosurfactants.<br>References Rang, M., et al.: J. Colloid Interface Sci., 209, 179 (1999); Hills, B., et al.: Magn. Reson. Imaging, 18, 319 (2000); Noordman, W., et al.: Appl. Environ. Microbiol., 68, 4502 (2002)<br></p>

<p>Applications Intermediate for the preparation of Metoprolol Acid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Hexadecanoic-9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-d17 Acid (CAS# 81462-28-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Amphiphilic molecule used in the synthesis of artificial cell membranes for diagnostics and therapeutics.<br>References Deckert, A.A., et al.: Langmuir, 11, 643 (1995); Charych, D., and Nagy, J.O.: Chemtech, 26(9), 24 (1996); Pan, J.J. and Charych, D.: Langmuir, 13, 1365 (1997)<br></p>

<p>Applications Desacetyl Forskolin is an analogue of Forskolin (F701800). Desacetyl Forskolin was tested for its ability to activate rat brain adenylate cyclase, activate detergent-solubilized rat brain adenylate cyclase, increase cyclic AMP in intact S49 wild-type cells, and inhibit the binding of 3H-forskolin to rat brain membranes.<br>References Desouza, N., et al.: Med. Res. Rev., 3, 201 (1983); Seamon, K., et al.: J. Med. Chem., 26, 436 (1983); Seguin, E., et al.: Planta Medica, 54, 4 (1988);<br></p>

<p>Stability Light Sensitive<br>Applications (9Z,12Z,15Z)-octadeca-9,12,15-trien-1-ol is an essential oil component of Osmanthus fragrans.<br>References Hu, C., et al.: Huaxue Shiji, 32, 231 (2010); Tian, G., et al.: Anhui Nongye Kexue, 36, 7214 (2008)<br></p>

<p>Applications Oxalic Acid Ethyl Ester is a useful synthetic intermediate. It is used to synthesize 2-substituted 3-aryl-4(3H)-quinazolinones with anticonvulsant activities. It is also used to prepare nonbenzamidine tetrazole derivatives as factor Xa inhibitors.<br>References Wolfe, J., et al.: J. Med. Chem., 33, 161 (1009); Quan, M., et al.: bioorg. Med. Chem. Lett., 13, 369 (2003)<br></p>

<p>Applications 9H-Hexadecafluorononanoic Acid (cas# 76-21-1) is a useful research chemical.<br></p>

<p>Stability Air and Moisture sensitive<br>Applications It is used in the production of lipid and fatty acids.<br>References Cerniglia, C., et al.: J. Bacteriol., 118, 844 (1974), Leahy, J., et al.: Microbiolog. Rev., 54, 305 (1990),<br></p>

<p>Applications 5-Bromopentanoic Acid Ethyl Ester was used in the preparation of S(γ-Carboxypropyl)-DL-homocysteine and S(δ-Carboxybutyl)-DL-homocysteine. It was also used in the preparation of ethyl 5-azidovalerate.<br>References Awad, W.: J. Biol. Chem., 258, 12790 (1983); Li, Z., et al.: Tetrahedron Lett., 45, 3143 (2004)<br></p>

<p>Applications Cetyl Stearate is a wax ester of stearic acid. Wax esters are esters between long chained fatty alcohols and fatty acids. Wax esters have significance in pharmaceutical and cosmetics applications and occur naturally in plants and animals. Stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.<br>References Wheatley, V., et al.: Biochem. J., 58, 167 (1954); Shichijo, S., et al.: Biochem. Med., 22, 256 (1979); Robosky, L., et al.: J. Lipid Res., 49, 686 (2008);<br></p>