Protacs and Impurities
GMB-475
CAS:2490599-18-1
GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.
Formula:
C43H46F3N7O7S
Purity:
100% - 98.78%
Color and Shape:
Solid
Molecular weight:
861.93
Ref: TM-T8488
1mg | 95.00 € | ||
5mg | 196.00 € | ||
10mg | 343.00 € | ||
25mg | 580.00 € | ||
50mg | 822.00 € | ||
100mg | 1,112.00 € | ||
500mg | 2,270.00 € | ||
1mL*10mM (DMSO) | 273.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dbet57
CAS:1883863-52-2
dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.
Formula:
C34H31ClN8O5S
Purity:
99.32% - 99.52%
Color and Shape:
Solid
Molecular weight:
699.18
Ref: TM-T5440
1mg | 49.00 € | ||
5mg | 95.00 € | ||
10mg | 152.00 € | ||
25mg | 272.00 € | ||
50mg | 423.00 € | ||
100mg | 612.00 € | ||
500mg | 1,265.00 € | ||
1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARV-771
CAS:1949837-12-0
ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.
Formula:
C49H60ClN9O7S2
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
986.64
Ref: TM-T5435
1mg | 60.00 € | ||
5mg | 118.00 € | ||
10mg | 184.00 € | ||
25mg | 366.00 € | ||
50mg | 546.00 € | ||
100mg | 781.00 € | ||
1mL*10mM (DMSO) | 201.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BSJ-03-123
CAS:2361493-16-3
BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.
Formula:
C47H56N10O11
Purity:
97.78% - 99.38%
Color and Shape:
Liquid
Molecular weight:
937.01
Ref: TM-T5395
1mg | 90.00 € | ||
2mg | 118.00 € | ||
5mg | 184.00 € | ||
10mg | 270.00 € | ||
25mg | 425.00 € | ||
50mg | 578.00 € | ||
100mg | 825.00 € | ||
500mg | 1,669.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PROTAC BRAF-V600E degrader-1
CAS:2417296-84-3
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.
Formula:
C48H54F2N10O10S
Purity:
99.43%
Color and Shape:
Solid
Molecular weight:
1001.07
Ref: TM-T8745
1mg | 109.00 € | ||
5mg | 292.00 € | ||
10mg | 383.00 € | ||
25mg | 625.00 € | ||
50mg | 844.00 € | ||
100mg | 1,126.00 € | ||
200mg | 1,528.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pomalidomide-PEG2-OH
CAS:2143097-10-1
Pomalidomide-PEG2-OH enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.
Formula:
C17H19N3O6
Purity:
99.98%
Color and Shape:
Solid
Molecular weight:
361.35
Ref: TM-T9383
1mg | 95.00 € | ||
5mg | 185.00 € | ||
10mg | 273.00 € | ||
25mg | 436.00 € | ||
50mg | 621.00 € | ||
100mg | 836.00 € | ||
200mg | 1,090.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346008
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
dBET6
CAS:1950634-92-0
dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). …
Formula:
C42H45ClN8O7S
Purity:
97.57% - 99.12%
Color and Shape:
Solid
Molecular weight:
841.37
Ref: TM-T5130
1mg | 52.00 € | ||
5mg | 95.00 € | ||
10mg | 166.00 € | ||
25mg | 302.00 € | ||
50mg | 481.00 € | ||
100mg | 699.00 € | ||
200mg | 878.00 € | ||
500mg | 1,287.00 € | ||
1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BSJ-4-116
CAS:2519823-34-6
BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription …
Formula:
C40H49ClN8O8S
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
837.38
Ref: TM-T9117
1mg | 54.00 € | ||
5mg | 109.00 € | ||
10mg | 176.00 € | ||
25mg | 368.00 € | ||
50mg | 591.00 € | ||
100mg | 884.00 € | ||
1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
dCBP-1
CAS:2484739-25-3
dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.
Formula:
C51H63F2N11O10
Purity:
98.21% - 99.12%
Color and Shape:
Solid
Molecular weight:
1028.11
Ref: TM-T9370
1mg | 93.00 € | ||
5mg | 183.00 € | ||
10mg | 323.00 € | ||
25mg | 551.00 € | ||
50mg | 782.00 € | ||
100mg | 1,084.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346009
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346006
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pomalidomide-PEG3-OH
CAS:2140807-36-7
Pomalidomide-PEG3-OH enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.
Formula:
C19H23N3O7
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
405.4
Ref: TM-T9384
1mg | 95.00 € | ||
5mg | 185.00 € | ||
10mg | 273.00 € | ||
25mg | 436.00 € | ||
50mg | 621.00 € | ||
100mg | 836.00 € | ||
200mg | 1,118.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346003
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gefitinib-based PROTAC 3
CAS:2230821-27-7
Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).
Formula:
C47H57ClFN7O8S
Purity:
97.29% - 98.25%
Color and Shape:
Solid
Molecular weight:
934.51
Ref: TM-T5437
2mg | 44.00 € | ||
5mg | 61.00 € | ||
10mg | 101.00 € | ||
25mg | 168.00 € | ||
50mg | 248.00 € | ||
100mg | 358.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
A1874
CAS:2064292-12-0
A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in …
Formula:
C58H62Cl3F2N9O7S
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
1173.59
Ref: TM-T5442
1mg | 212.00 € | ||
2mg | 296.00 € | ||
5mg | 453.00 € | ||
10mg | 644.00 € | ||
25mg | 1,016.00 € | ||
50mg | 1,374.00 € | ||
100mg | 1,850.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARD-2128
CAS:2222111-87-5
ARD-2128: potent oral PROTAC that degrades AR, curbing prostate cancer growth with no toxicity.
Formula:
C45H50ClN7O6
Purity:
98.80%
Color and Shape:
Solid
Molecular weight:
820.37
Ref: TM-T39695
1mg | 213.00 € | ||
2mg | 319.00 € | ||
5mg | 540.00 € | ||
10mg | 777.00 € | ||
25mg | 1,180.00 € | ||
50mg | 1,570.00 € | ||
100mg | 2,133.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Homo-PROTAC cereblon degrader 1
CAS:2244520-98-5
Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only …
Formula:
C32H32N6O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
660.63
Ref: TM-T13721
1mg | 213.00 € | ||
5mg | 535.00 € | ||
10mg | 763.00 € | ||
25mg | 1,160.00 € | ||
50mg | 1,570.00 € | ||
100mg | 2,126.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
THAL-SNS-032
CAS:2139287-33-3
THAL-SNS-032 is a selective CDK9 degrader PROTAC.
Formula:
C40H52N8O10S2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
869.02
Ref: TM-T17069
1mg | 114.00 € | ||
5mg | 268.00 € | ||
10mg | 403.00 € | ||
25mg | 642.00 € | ||
50mg | 917.00 € | ||
100mg | 1,243.00 € | ||
1mL*10mM (DMSO) | 409.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346007
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024