Protacs and Impurities
ACBI1
CAS:2375564-55-7
ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades …
Formula:
C49H58FN9O7S
Purity:
97.54% - 98.15%
Color and Shape:
Solid
Molecular weight:
936.1
Ref: TM-T17350
1mg | 96.00 € | ||
5mg | 223.00 € | ||
10mg | 359.00 € | ||
25mg | 600.00 € | ||
50mg | 857.00 € | ||
100mg | 1,154.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
dBET1
CAS:1799711-21-9
dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers …
Formula:
C38H37ClN8O7S
Purity:
98.14% - 99.3%
Color and Shape:
Solid
Molecular weight:
785.27
Ref: TM-T4495
1mg | 52.00 € | ||
5mg | 103.00 € | ||
10mg | 168.00 € | ||
25mg | 279.00 € | ||
50mg | 446.00 € | ||
100mg | 678.00 € | ||
500mg | 1,397.00 € | ||
1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346001
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MZ 1
CAS:1797406-69-9
MZ 1 is a BRD4 protein degrader based on PROTAC technology.
Formula:
C49H60ClN9O8S2
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
1002.64
Ref: TM-T5436
1mg | 51.00 € | ||
5mg | 157.00 € | ||
10mg | 198.00 € | ||
25mg | 304.00 € | ||
50mg | 399.00 € | ||
100mg | 581.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346002
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARV-471
CAS:2229711-68-4
ARV-471 (Vepdegestrant) is a orally active Cereblon -based estrogen receptor (ER) PROTAC degrader. ARV-471 is …
Formula:
C45H49N5O4
Purity:
100% - 99.85%
Color and Shape:
Solid
Molecular weight:
723.9
Ref: TM-T39710
1mg | 247.00 € | ||
5mg | 611.00 € | ||
10mg | 869.00 € | ||
25mg | 1,292.00 € | ||
50mg | 1,757.00 € | ||
1mL*10mM (DMSO) | 846.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TD-165
CAS:2305936-56-3
TD-165, a PROTAC-based cereblon (CRBN) degrader, consists of a cereblon (CRBN) ligand-binding group, a linker, …
Formula:
C46H59N7O8S
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
870.07
Ref: TM-T18787
1mg | 112.00 € | ||
5mg | 229.00 € | ||
10mg | 345.00 € | ||
25mg | 691.00 € | ||
50mg | 1,003.00 € | ||
100mg | 1,375.00 € | ||
1mL*10mM (DMSO) | 336.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
CP5V
CAS:2509359-75-3
CP5V, a PROTAC, degrades Cdc20, halts mitosis, and inhibits cancer growth by targeting it for …
Formula:
C46H66Cl3N9O12S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1075.49
Ref: TM-T10875
1mg | 369.00 € | ||
5mg | 814.00 € | ||
10mg | 1,359.00 € | ||
25mg | 2,014.00 € | ||
50mg | 2,698.00 € | ||
100mg | 3,672.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ARV-393
CAS:2851885-95-3
ARV-393 is a BCL6 PROTAC degrader with DC50 and GI50 values of <1 nM in …
Formula:
C46H53O7ClFN9
Color and Shape:
Soild
Molecular weight:
898.43
Ref: TM-T84316
1mg | 250.00 € | ||
5mg | 623.00 € | ||
10mg | 986.00 € | ||
25mg | 1,957.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
MI-389
CAS:2222635-92-7
MI-389 is a protein degrader, targeting the translation termination factor G1 to S phase transition …
Formula:
C35H35FN6O6
Color and Shape:
Solid
Molecular weight:
654.69
Ref: TM-T33380
25mg | 1,100.00 € | ||
50mg | 1,436.00 € | ||
100mg | 2,330.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
SJF620
CAS:2376187-16-3
SJF620 is a potent degrader of PROTAC BTK(DC50 : 7.9 nM).
Formula:
C41H44N8O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
760.84
Ref: TM-T13887
25mg | 1,410.00 € | ||
50mg | 1,846.00 € | ||
100mg | 2,322.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
FC 11
CAS:2271035-37-9
FC 11 is a reversible FAK PROTAC Degrader with DC50 of 40-370 pM and degrades …
Formula:
C41H42F3N13O9S
Color and Shape:
Solid
Molecular weight:
949.91
Ref: TM-T41164
25mg | 583.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
C004019
CAS:2417159-57-8
C004019 is a small molecule PROTAC capable of targeting tau for selective protein degradation from …
Formula:
C49H70N12O9S2
Purity:
99.37%
Color and Shape:
Soild
Molecular weight:
1035.29
Ref: TM-T67834
1mg | 244.00 € | ||
5mg | 598.00 € | ||
10mg | 875.00 € | ||
25mg | 1,280.00 € | ||
50mg | 1,743.00 € | ||
100mg | 2,345.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
XY028-140
CAS:2229974-83-6
XY028-140 is a selective CDK4/6 inhibitor and degrader, acting via PROTAC with ligands for Cereblon …
Formula:
C39H40N10O7
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
760.8
Ref: TM-T36694
1mg | 40.00 € | ||
5mg | 86.00 € | ||
10mg | 123.00 € | ||
25mg | 245.00 € | ||
50mg | 392.00 € | ||
100mg | 583.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
MS67
CAS:2407452-77-9
MS67 selectively degrades WDR5 with a 63 nM Kd, has anticancer effects, and is inactive …
Formula:
C52H59F4N9O7S
Color and Shape:
Liquid
Molecular weight:
1030.14
Ref: TM-T39976
10mg | 889.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
(Iso)-MS4322
CAS:2601727-80-2
(Iso)-MS4322 ((Iso)-YS43-22) is a protein arginine methyltransferase 5 (PRMT5 ) degrader with potential anticancer activity.
Formula:
C55H76N10O12S
Purity:
98.85% - 99.76%
Color and Shape:
Solid
Molecular weight:
1101.32
Ref: TM-T40233
1mg | 457.00 € | ||
5mg | 1,009.00 € | ||
10mg | 1,480.00 € | ||
25mg | 2,196.00 € | ||
50mg | 2,969.00 € | ||
100mg | 4,005.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
QCA570
CAS:2207569-08-0
QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 …
Formula:
C39H33N7O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
695.79
Ref: TM-T16701
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Monday 3 Mar 2025
MS8815
CAS:2855085-25-3
MS8815 is a selective EZH2 PROTAC degrader with IC50 of 8.6 nM, used in triple-negative …
Formula:
C65H87N9O8S
Color and Shape:
Liquid
Molecular weight:
1154.51
Ref: TM-T74675
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Monday 3 Mar 2025
PROTAC FKBP Degrader-3
CAS:2079056-43-0
PROTAC FKBP Degrader-3, with FKBP and VHL binding groups linked, is a potent FKBP degrader.
Formula:
C68H90N6O17S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1295.54
Ref: TM-T18610
1mg | 467.00 € | ||
5mg | 939.00 € | ||
10mg | 1,409.00 € | ||
25mg | 2,071.00 € | ||
50mg | 2,817.00 € | ||
100mg | 3,734.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025