Primary Antibodies
Subcategories of "Primary Antibodies"
- Cancer Research Antibodies(3,620 products)
- Cardiovascular Antibodies(2 products)
- Developmental Biology(751 products)
- Epigenetics Antibodies(162 products)
- Immunology Antibodies(2,551 products)
- Metabolism Antibodies(279 products)
- Microbiology Antibodies(740 products)
- Signal Transduction(2,717 products)
- Tags & Cellular Markers(33 products)
Found 75459 products of "Primary Antibodies"
APP antibody
APP antibody was raised in goat using a synthetic peptide corresponding to amino acid residues 44-63 of the N-terminus of the human alzheimer’s APP as the immunogen.Purity:Min. 95%Anti-Ptgdr2 antibody - 0.5mg/mL
Prostaglandin D2 ligand activates G-protein-coupled receptors encoded by Ptgdr2, notably CRTh2, which mediate type 2 cytokine production, apoptosis inhibition and pro-inflammatory chemotaxis of Th2 cells, basophils and eosinophils, making the PGD2-CRTh2 pathway a vital factor in the regulation of allergic inflammation. Single nucleotide polymorphisms within the 3' UTR of the Ptgdr2 gene have been linked to asthma susceptibility, while Ptgdr2 signalling has been associated with self-renewal limitation of gastric cancer cells._x000D_
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The prostaglandin D and prostaglandin D2 receptor CRTh2 is a chemoattractant receptor homologue that, along with two of its known isoforms, belongs to the G-protein-coupled leukocyte chemoattractant receptor family. Under PGD2 ligation signals, CRTh2, D-prostanoid (DP1) and thromboxane prostanoid (TP) signals are thought to mediate the biological action of prostaglandin D2 through stimulating calcium release from intracellular stores.Anti-TAS2R39 antibody - 2mg/mL
Bitter taste receptors (TAS2Rs) are predominantly found in the mouth and other tissues, including the gut and lungs, and cell types such as immune cells. Â Taste receptor type 2 member 39 (TAS2R39) is a receptor that plays a prominent role in the perception of bitterness. TAS2R39 may also play a role in sensing the chemical composition of the gastrointestinal content. The activity of the TAS2R39 receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. TAS2Rs recognise a wide variety of compounds, and work with TAS2R39 has helped identify antagonist compounds to block the perceived bitterness of medications. 6-methoxyflavanones are antagonists of TAS2R39, the methoxy group on the 6-position of the flavanone's A-ring is the critical region for exerting inhibitory activity.
Rabbit anti Human IgE
Rabbit anti Human IgE is a highly effective neutralizing antibody that targets human serum. It has been specifically developed to combat the presence of autoantibodies and chemokines in the body. This antibody is widely used in the field of Life Sciences and has shown remarkable results in neutralizing agonist proteins. Additionally, Rabbit anti Human IgE has been proven to react with various proteins such as serum albumin protein and epidermal growth factor. With its high reactivity, this monoclonal antibody is an excellent tool for researchers studying cell antigens and seeking to develop targeted therapies. Trust Rabbit anti Human IgE to provide accurate and reliable results in your scientific endeavors.
Purity:Min. 95%Free hCG β recombinant antibody
A recombinant monoclonal antibody derived from mouse monoclonal antibody to free Beta-hCG (clone M15294 expressed in HEK cell line).Human chorionic gonadotropin (hCG) is a hormone produced by the placenta during pregnancy and is commonly measured in blood or urine tests to confirm pregnancy.
Theophylline antibody
Theophylline antibody was raised in mouse using theophylline conjugated to KLH as the immunogen.S100 antibody
S100 antibody was raised in mouse using purified bovine brain S100 protein as the immunogen.
Anti-MGAT1 antibody - 2mg/mL
Acyl-CoA:monoacylglycerol acyltransferase 1 (MGAT1) acylates monoacylglycerol to form diacylglycerol. MGAT activity is part of the MGAT pathway which allows the storage of neutral triacylglycerol (TAG). This is an auxiliary pathway to the glycerol-3-phosphate (G-3-P) pathway. MGAT1 is highly expressed in adipocytes and the liver; it may function to suppress aberrant lipolysis, which can lead to steatosis. MGAT isoforms (MGAT1, MGAT2, MGAT3) are increased in humans and mouse models of non-alcoholic fatty liver disease (NAFLD). Antisense oligonucleotides (ASO) have been used to reduce hepatic MGAT activity, which was independent of MGAT1. This improves hepatic insulin sensitivity and glucose metabolism without affecting hepatic DAG or TAG levels in obese mice models. The TAG synthesis in steatosis associated with lipodystrophy and obesity minimally depends on MOGAT1. The study of MGAT1 aims to improve understanding of insulin resistance and steatosis and better elucidate the function of MGAT1 in comparison to MGAT2 and MGAT3.
Goat anti Cat IgG (H + L) (FITC)
Goat anti-cat IgG (H+L) (FITC) was raised in goat using feline IgG whole molecule as the immunogen.Purity:Min. 95%RNA Polymerase II antibody
RNA polymerase II antibody was raised in mouse using purified RNA polymerase II as the immunogen.
Donkey anti Rabbit IgG (H + L) (Fab'2) (Alk Phos)
Donkey anti-rabbit IgG (H + L) (Fab'2) (Alk Phos) was raised in donkey using rabbit IgG (H&L) as the immunogen.
Anti-NGF antibody R1G - 1mg/mL
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide involved in the regulation of specific neurons through control of neuronal growth, maintenance, proliferation, and survival. NGF protein functions as the extracellular ligand for the NTRK1 or the NGFR receptors on the surface of neurons, initiating signalling cascades inside the cell. Binding of NGF causes neurons to mature and differentiate; additionally, NGF is critical in the survival of sympathetic and sensory neurons, as in the absence of NGF these cells will undergo apoptosis.NGF is capable of binding with two classes of receptors, both tropomyosin receptor kinase A (TrkA) and low-affinity NGF receptor (LNGFR) act as ligands for NGF, activating signalling cascades. These receptors are associated with neurodegenerative diseases, implying the potential of NGF as a therapeutic drug target.Anti-IL23A antibody - 2mg/mL
Together with IL12B, IL23A forms part of the heterodimeric cytokine IL-23 which functions in innate and adaptive immunity. IL-23 is a member of the IL-12 family of cytokines that includes IL-12, IL-35, IL-27, and IL-39. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R and activates the Jak-Stat signaling cascade. IL-23 is a key driver of Th17-mediated immune response during infection and inflammation and its over production is involved in several cancers.
AF488 Anti-mGluR2 antibody - 0.36mg/mL
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.Purity:Min. 95%Triiodothyronine antibody
Triiodothyronine antibody was raised in rabbit using T3-BSA as the immunogen.
VEGF antibody
VEGF antibody was raised in mouse using highly pure recombinant human VEGF165 as the immunogen.HIV2 gp105 antibody
HIV2 gp105 antibody was raised in rabbit using purified, full length recombinant gp105 (HIV-2 ROD) as the immunogen.
Purity:Min. 95%Haloperidol antibody
Haloperidol antibody was raised in rabbit using haloperidol-KLH as the immunogen.
Purity:Min. 95%Goat anti Rabbit IgG
Goat anti rabbit IgG was raised in goat using highly purified rabbit IgG as the immunogen.
Purity:Min. 95%Neu antibody
Neu antibody was raised in mouse using RAC311 Cells transfected with SV40-neu construct, expressing human neu protein as the immunogen.
Purity:Min. 95%B2M antibody
The B2M antibody is a powerful tool in the field of Life Sciences. This monoclonal antibody specifically targets and binds to β-catenin, a key protein involved in cell signaling and development. By binding to β-catenin, the B2M antibody can modulate its activity and downstream signaling pathways.
Anti-HRVA16 di-uridylated antibody R2G - 0.2mg/mL
human rhinovirus (HRV) VPg uridylylation.
Purity:Min. 95%HSV1 gE antibody
HSV1 gE antibody was raised in mouse using herpes simplex virus I glycoprotein E (gE) as the immunogen.
HIV1 gp41 antibody (HRP)
HIV1 gp41 antibody (HRP) was raised in mouse using purified, full length Recombinant gp41 (HIV-1) produced in E. coli expression system as the immunogen.
Anti-SLC12A2 antibody R1G - 1mg/mL
The SLC12 family consists of nine member proteins, SLCA1 through to SLC12A9. Solute Carrier Family 12 Member 2 (SLC12A2) encodes a protein used in mediating the cotransport and reabsorption of Na+, K+ and 2Cl- ions (NKCC), it is a membrane-bound symporter channel needed for both epithelial absorption and secretion of ions. SLC12A2 spans the membrane and is necessary in maintaining ionic balance, cell volume and overall homeostasis of a cell.SLC12A2 is shown to be involved in neurodevelopment, specifically in the cortex, and is associated with neurodevelopmental disorders, with SLC12A2 mutation rate being significantly higher in individuals with neurodevelopmental issues. Additionally, mutations in SLC12A2 have been shown to cause issues with sensorineural pathways, causing hearing loss and deafness. Research into SLC12A2 and the SLC12 family as a whole could be beneficial in finding treatments for these complex neuronal issues.
Orosomucoid antibody
Orosomucoid antibody was raised in rabbit using rat alpha-1 acid glycoprotein as the immunogen.
Purity:Min. 95%SARS Coronavirus Antibody
The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is a powerful antituberculosis drug belonging to the rifamycins class. It is highly effective in treating tuberculosis infections due to its bactericidal activity. By binding to DNA-dependent RNA polymerase, it inhibits bacterial growth, preventing transcription and replication. This drug has been extensively studied and proven to be active using the patch-clamp technique on human erythrocytes. Metabolized through various transformations, including hydrolysis, oxidation, reduction, and conjugation, it specifically targets Mycobacterium tuberculosis strains and inhibits cell growth. Trust this drug for its effectiveness in combating tuberculosis infections.
