Lipids

Applications Campestanol can be used as analyte in biological and analytical studies for the determination of 22 natural brassinosteroids in a minute sample of plant tissue by UHPLC-ESI-MS/MS.
References Tarkowska, D., et al.: Anal. Bioanal. Chem., 408, 6799-6812 (2016)

Stability Light Sensitive
Applications cis-7,10,13,16-Docosatetraenoic Acid has been identified as a protein kinase inhibitor, affecting serotonin levels in studies.
References Mirnikjoo, B. et al.: J. Biol. Chem., 276, 10888 (2001);

Applications An impurity of Griseofulvin (G787500).
References Oda, T., et al.: Chem. Pharma. Bull., 34, 858 (1986),

Impurity Atorvastatin EP Impurity E
Stability Hygroscopic
Applications (3S,5S)-Atorvastatin Sodium Salt (Atorvastatin EP Impurity E) is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18. 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)

Applications Ostreasterol is a marine steroid, and also a derivative compound of hydroxycholesterol (H918040), which functions as the main cholesterol elimination product of the brain and was found to be increased in serum of Alzheimer patients.
References Kolsch, H., et al.: J. Neural. Transm., 108, 475 (2001); Gamba, P., et al.: Aging. Cell., 10, 403 (2011); Seet, R.C.S., et al.: Free. Rad. Biol. Med., 48, 560 (2010);

Applications 11-Deoxy-18-hydroxycorticosterone is an analog of Corticosterone (C695700); a glucocorticoid and intermediate in the biosynthesis of Aldosterone (A514700) which is an adrenocortical steroid isolated from the adrenal cortex.
References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009); Bailey, M., et al.: J. Immunol., 182, 7888 (2009); Brunton, P., et al.: J. Neurosci., 29, 6449 (2009); Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009)

Applications (3β)-3,25-Dihydroxycholest-5-en-7-one is a useful synthetic intermediate in the synthesis of 3β,7α,25-Trihydroxycholest-5-ene (T795075); a potent agonist of GPR183 that induces specific activation of the receptor.
References Antunes, L., et al.: Antimicrob. Agents. Chemtherap., 55, 1494 (2011); Schwarz, M., et al.: J. Cin. Invest., 106, 1175 (2000); Zhang, J., et al.: BIochem. J., 322, 175 (1997)

Applications Glycolithocholic-2,2,4,4-d4 Acid (CAS# 2044276-16-4) is a useful isotopically labeled research compound.

Stability Hygroscopic
Applications Glycocholic-2,2,4,4-d4 Acid was an analyte found in serum bile acids. Potential application for diagnosis of pediatric liver and intestinal diseases in humans.
References Fu, X., et al.: Clin. Chem. Lab. Med., 58, 787 (2020)

Stability Hygroscopic
Applications rac 1-Oleoyl Glycerol is a monoglyceride. These fatty acid esters are useful for the improvement of texture and flavor of beverages.
References Lee, T.-H., et al.: J. Nat. Prod., 72, 1960 (2009)

Applications The 22R-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.
References Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),