Nucleotides
Nucleotides are organic compounds that serve as the building blocks of nucleic acids, essential for the formation of DNA and RNA. Each nucleotide is composed of a nitrogenous base, a sugar molecule, and one or more phosphate groups. These nucleotides join together to form long chains, creating the genetic material that carries and transmits genetic information in all living organisms. In this section, you will find a wide variety of nucleotides crucial for research in genetics, molecular biology, and biochemistry. They are fundamental for studying genetic processes, synthesizing nucleic acids, and developing diagnostic and therapeutic tools. At CymitQuimica, we offer high-quality nucleotides to support your scientific research and applications, ensuring precision and reliability in your experiments
Subcategories of "Nucleotides"
Found 2638 products of "Nucleotides"
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2'-Deoxy-N4-methylcytidine
CAS:2'-Deoxy-N4-methylcytidine is a modified nucleoside that is used to inhibit the activity of protein kinases. It has been shown to inhibit the function of two different types of enzymes, eukaryotic protein kinase and bacterial RNA polymerase. 2'-Deoxy-N4-methylcytidine inhibits the activity of these enzymes by modifying their structure, which in turn prevents them from carrying out their normal functions. This modification can be achieved through deamination or protonation reactions with this drug. The effects of this drug are nonparametric and are observed at transcript levels.Formula:C10H15N3O4Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:241.24 g/mol2'-Deoxy-3'-O-DMT-N2-Isobutyrylguanosine
CAS:2'-Deoxy-3'-O-DMT-N2-Isobutyrylguanosine is a synthetic nucleoside that has the ability to activate and inhibit the growth of cancer cells. This compound is a phosphoramidite, and it has been modified by the addition of an isobutyrate group at the 2' position. The structure of this nucleoside is similar to that of natural guanosine, but with an additional 2' oxygen atom. This modification can be used for inhibition of DNA synthesis in cells and may have antiviral effects.Formula:C35H37N5O7Purity:Min. 97 Area-%Molecular weight:639.71 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2',2'-difluorocytidine
CAS:Used as an intermediate for the preparation of modified oligonucleotides and other cytidine derivatives containing a 2',2'-difluoro modification.Formula:C23H19F2N3O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:471.42 g/mol2'-Deoxyadenosine-5'-triphosphate trisodium
CAS:2'-Deoxyadenosine-5'-triphosphate or dATP, is a nucleotide used by cells to synthesize DNA molecules. 2'-Deoxyadenosine-5'-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of 2'-deoxyadenosine-5'-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).Formula:C10H13N5O12P3·3NaPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:557.13 g/mol2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate sodium, 100 mM aqueous solution
2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate sodium, 100 mM aqueous solution is a synthetic nucleoside that can be used as an antiviral and anticancer agent. The drug inhibits viral replication by inhibiting the synthesis of DNA. The drug also suppresses tumor growth by inhibiting the production of RNA and DNA in cancer cells.Formula:C10H18N3O14P3•NaxPurity:Min. 90 Area-%Color and Shape:Clear LiquidMolecular weight:497.18 g/mol2',3'-Dideoxy-3'-fluoroguanosine
CAS:2',3'-Dideoxy-3'-fluoroguanosine is a synthetic nucleoside analog based on guanosine. It is structurally altered to interfere with DNA or RNA synthesis, making it potentially useful as an antiviral or anticancer agent.Formula:C10H12FN5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:269.24 g/mol5-Formyl-2'-O-methylcytidine
CAS:5-Formyl-2'-O-methylcytidine is a molecule that is involved in cellular processes such as DNA methylation, the addition of a methyl group to the 5 position of a cytosine residue. It has been shown to be an important epigenetic regulator and can be used as a strategy to treat tuberculosis. 5-Formyl-2'-O-methylcytidine is synthesized from guanine, which undergoes conversion into cytosine via enzymatic modification. This process is catalyzed by methyltransferase enzymes and it is usually carried out with S-adenosylmethionine (SAM) as the methyl donor. The product then converts back into guanine through deamination, which can be catalyzed by either adenine phosphoribosyltransferase or adenylate kinase.Formula:C11H15N3O6Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:285.25 g/mol2',3',5'-Tri-O-acetyladenosine
CAS:2',3',5'-Tri-O-acetyladenosine is a chemically protected form of adenosine with potential for use as an intermediate in nucleoside synthesis and nucleic acid chemistry. The hydroxyl (–OH) groups at the 2′, 3′, and 5′ positions of the ribose are protected by acetyl groups (–COCH₃), which can prevent unwanted chemical reactions during chemical synthesis.
Formula:C16H19N5O7Purity:Min. 95%Color and Shape:PowderMolecular weight:393.35 g/mol5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
CAS:5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine is an antiviral monophosphate nucleoside. It has been shown to be a novel, high purity, and CAS No. 251647-50-4. It is a modified nucleic acid analogue that acts as an activator of ribonucleotide reductase and DNA polymerase. The anticancer activity of this product may be due to its ability to inhibit the synthesis of diphosphate nucleotides.Formula:C38H43N5O9Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:713.78 g/moldNTP pre-mixes, 25mM aqueous solution
CAS:dATP, dTTP, dCTP and dGTP pre-mixed in a single vial
Purity:Min. 95%2'-Deoxy-5-methylcytidine-5'-monophosphate disodium
CAS:2'-Deoxy-5-methylcytidine-5'-monophosphate disodium (2D5MCP) is a nucleoside analog that inhibits the synthesis of DNA. It is used in the treatment of cervical cancer and other cancers that are dependent on DNA synthesis. 2D5MCP works by binding to and inhibiting the activity of an enzyme called DNA polymerase, which is needed for DNA replication. This drug also has been shown to inhibit fatty acid synthase enzymes and surface glycoprotein enzymes, which may be responsible for its anti-cancer effects. 2D5MCP has been shown to have an effective dose range between 50 and 150 mg/kg, with no significant side effects seen at doses up to 300 mg/kg. 2D5MCP does not bind to plasma proteins or erythrocytes, so it can be administered intravenously without risk of tissue damage caused by osmotic lysis.Formula:C10H14N3O7PNa2Purity:Min. 95%Color and Shape:White PowderMolecular weight:365.19 g/mol2'-Deoxy-2'-fluorouridine-5'-triphosphate tetralithium
CAS:2'-Deoxy-2'-fluorouridine-5'-triphosphate tetralithium (2'DFUR) is a fatty acid that is resistant to many antibacterial agents. 2'DFUR inhibits the biosynthesis of bacterial cell walls, leading to cell death. This drug has been shown to have potent antibacterial activity against Staphylococcus strains and other bacteria. The mechanism of action is not yet fully understood, but it may involve inhibition of nucleotidyltransferase and aminopropyl transferase enzymes.Formula:C9H11FN2O14P3Li4Purity:Min. 95%Color and Shape:PowderMolecular weight:510.87 g/mol5'-Deoxy-5'-iodothymidine
CAS:5'-Deoxy-5'-iodothymidine is an antiviral nucleoside that inhibits viral replication by competing with the natural substrate, deoxyribonucleotide triphosphate, for incorporation in DNA. 5'-Deoxy-5'-iodothymidine has been shown to be a novel antiviral agent and an activator of host immune responses against virus infections. 5'-Deoxy-5'-iodothymidine is also used as an intermediate for the synthesis of phosphoramidites, which are used in the production of DNA.Formula:C10H13IN2O4Purity:Min. 95%Molecular weight:352.13 g/mol2'-Deoxyadenosine-3'-monophosphate sodium salt
CAS:2'-Deoxyadenosine-3'-monophosphate sodium salt (dAMP) is a novel nucleoside analog that is the sodium salt of 2'-deoxyadenosine-3'-monophosphate. It has shown anticancer and antiviral activity in vitro, as well as cytotoxicity against some human cancer cell lines. It has also been shown to be active against HIV-1 and herpes simplex virus type 1. The drug is modified with an amino group at the 2' position of the ribose sugar, which increases its stability in vivo and reduces its toxicity. This product also contains high purity, high quality, and novel deoxyribonucleosides that are synthesized by a phosphoramidite method.Formula:C10H14N5O6P·2NaPurity:Min. 95%Color and Shape:PowderMolecular weight:377.2 g/mol1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-methyluracil
CAS:1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-methyluracil is a nucleoside analog for research applications. It contains a β-D-arabinofuranose sugar and the fluorine (F) substitution at the 2'-position enhances stability and improves resistance to enzymatic degradation. The 5-methyluracil base makes it structurally similar to thymidine, allowing it to be recognized by DNA polymerases and kinases.Formula:C10H13FN2O5Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:260.22 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl)thymine
CAS:1-(3`,5`-Di-O-benzoyl-2`-deoxy-2`-fluoro-beta-L-arabinofuranosyl)thymine is a nucleoside analog with modifications that influence its biological activity. It contains a thymine base and 3',5'-Di-O-benzoyl groups that protect hydroxyl functionalities during chemical synthesis. This molecule also has the sugar 2'-Deoxy-2'-fluoro-β-L-arabinofuranose made up of an L-arabinose configuration and a 2'-Fluoro substitution, the latter of which enhances stability and resistance to enzymatic degradation.Formula:C24H21FN2O7Purity:Min. 95%Molecular weight:468.43 g/molNADPH 4Na - min 95%
CAS:Beta-nicotinamide adenine dinucleotide phosphate sodium salt (NADPH) is a coenzyme that mediates various biological processes. It’s a regenerating electron donor in cellular antioxidation systems and a regulator of energy metabolism and mitochondrial functions. It mediates calcium homeostasis via the generation of cyclic ADP-ribose and modulates several key factors in cell death such as mitochondrial permeability transition and poly(ADP-ribose) polymerase-1 (PARP1).Formula:C21H26N7O17P3·4NaPurity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:833.35 g/mol5'-O-Levulinoylthymidine
CAS:5'-O-Levulinoylthymidine is a novel nucleoside analog that inhibits viral proliferation by inhibiting viral RNA polymerase. This drug is also an activator of ribonucleotide reductases, which are enzymes that synthesize deoxyribonucleotides from ribonucleotides. 5'-O-Levulinoylthymidine has been shown to inhibit the growth of cancer cells in vitro and in vivo. It has also been shown to be effective against HIV-1 infection in vitro.Formula:C15H20N2O7Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:340.33 g/mol3'-Deoxy-3'-fluoroguanosine
CAS:3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that is used for the treatment of viral hepatitis, cancer, and other diseases. 3'-Deoxy-3'-fluoroguanosine inhibits the replication of RNA by binding to the replicon. It binds to the RNA polymerase in a pharmacophore-based manner and inhibits its activity. When combined with other drugs, it has been shown to increase their efficacy. The combination of 3'-deoxy-3'-fluoroguanosine with interferon alpha 2b for the treatment of Hepatitis B has been shown to be more effective than either drug alone. The inhibition of cellular growth by 3'-deoxy-3'-fluoroguanosine may be due to its ability to inhibit rna synthesis.Formula:C10H12N5O4FPurity:Min. 95%Color and Shape:White PowderMolecular weight:285.23 g/molGuanosine 5'-monophosphate
CAS:Guanosine 5'-monophosphate, also known as GMP, is a ribonucleoside monophosphate that becomes incorporated into RNAs when phosphorylated to GTP.Formula:C10H14N5O8PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:363.22 g/mol
