Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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5-Formylamino-4-imidazolecarboxamide ribonucleotide
CAS:5-Formylamino-4-imidazolecarboxamide ribonucleotide is a nucleoside that is synthesized from 5-aminoimidazole ribonucleotide. It has antiviral and anticancer properties and is used as a precursor for the synthesis of other nucleosides. 5-Formylamino-4-imidazolecarboxamide ribonucleotide can be used in the preparation of oligodeoxyribonucleotides, which are involved in DNA replication, transcription, and translation. This compound also has been shown to inhibit the growth of cells with HIV or cancerous cells.Formula:C10H15N4O9PPurity:(Elemental Analysis) Min. 85%Molecular weight:366.22 g/molNicotinic acid adenine dinucleotide sodium
CAS:Nicotinic acid adenine dinucleotide sodium (NAAD) is a novel anticancer and antiviral agent. NAAD is an analog of nicotinamide adenine dinucleotide (NAD) that has been modified to include a sodium ion. This modification inhibits the synthesis of DNA and RNA, which are required for cell division and replication. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. In addition, NAAD suppresses viral replication by inhibiting protein synthesis in cells infected with HIV-1 or influenza virus. NAAD has also been shown to be a potent inhibitor of ribonucleoside reductase, which converts ribonucleosides into deoxyribonucleosides. This inhibition prevents the conversion of diphosphate nucleotides into monophosphate nucleotides, which are necessary for DNA synthesis.Formula:C21H26N6O15P2•NaPurity:Min. 95%Molecular weight:687.4 g/molMyristoyl coenzyme A
CAS:Myristoyl coenzyme A is a potential drug that inhibits the binding of human pathogens to protein. It also has been shown to have potential as an inhibitor for reactions involving myristoylation, which is a process where proteins are modified with myristic acid. Myristoyl coenzyme A was synthesized using titration calorimetry and in vitro assays. The compound has been shown to have the ability to inhibit polymerase chain reaction (PCR) and reduce the growth of bacteria in vitro. Myristoyl coenzyme A may be useful in treating metabolic disorders and infectious diseases such as AIDS, tuberculosis, and malaria.Formula:C35H62N7O17P3S·H2OPurity:Min. 90%Color and Shape:White PowderMolecular weight:995.91 g/mol(E)-2'-Deoxy-2'-(fluoromethylene)cytidine
CAS:(E)-2'-Deoxy-2'-(fluoromethylene)cytidine is a cytostatic compound that inhibits DNA synthesis in tumor cells. It has been shown to be more potent than tezacitabine and hl-60 cells, as well as being less toxic than benzimidazole compounds. This analog of cytosine has been shown to have potent antitumor activity against carcinoma cell lines and myeloid leukemia cell lines. The oral prodrug form of this drug has been shown to be an effective treatment for myeloid leukemia in mice.Formula:C10H12FN3O4Purity:Min. 95%Molecular weight:257.22 g/molLevovirin
CAS:Controlled ProductApplications Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin (R414475) with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.
References Ramasamy, K.S. et al.: J. Med. Chem., 43, 1019 (2000); Fang, C. et al.: J. Appl. Toxicol., 23, 453 (2003):Formula:C8H12N4O5Color and Shape:NeatMolecular weight:244.22,6-Diamino-9-(3'-O-methyl-b-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(3'-O-methyl-b-D-ribofuranosyl)purine is an activator of antineoplastic drugs. It is a synthetic nucleoside that is modified at the 2' and 6' positions. The modification of the 2' position increases the stability and bioavailability of the drug in vivo. This product can be used to synthesize deoxyribonucleosides, phosphoramidites, ribonucleotides, or antiviral drugs.Formula:C11H16N6O4Purity:Min. 95%Molecular weight:296.29 g/molCytidine-5'-carboxylic acid
CAS:Cytidine-5'-carboxylic acid is a member of the family of phenylephrine, which is a solid-phase peptide synthesized by reacting amino acids with N,O-bis(trimethylsilyl)acetamide and trimethylchlorosilane. Cytidine-5'-carboxylic acid is known to modulate substances that affect cell membrane properties and cause contraction in isolated rat stomachs. It has been shown to bind to the receptor agonist in laboratory animals. The concentration-response curve for cytidine-5'-carboxylic acid was determined in isolated rat stomach preparations.Formula:C9H11N3O6Purity:Min. 95%Molecular weight:257.2 g/mol3'-Deoxy-5'-O-DMT-3'-fluoro-thymidine
CAS:3'-Deoxy-5'-O-DMT-3'-fluoro-thymidine (3'DFT) is a nucleoside that can be used as an anticancer drug. It is synthesized by the replacement of the 3'-hydroxyl group with a fluorine atom in 5'-O-DMT-3'-fluoro-thymidine. The synthesis of 3'DFT starts with the reaction of 5'O-(4,4'-dimethoxytrityl)-3'-deoxyuridine and 1,2,4,5-tetraisopropyldiazoacetate to form 5'O-(4,4'-dimethoxytrityl)-3'-deoxythymidine. This is followed by a reduction of the ester group to produce 5'O-(4,4'dimethoxytrityl)-3'F-thymidine. An acetate group is then added toFormula:C31H31FN2O6Purity:Min. 95%Molecular weight:546.59 g/mol1-(a-D-Mannopyranosyl)-6-methoxypurine
1-(a-D-Mannopyranosyl)-6-methoxypurine is a synthetic nucleoside that is an activator for the purine receptor. It has been shown to inhibit the growth of various tumor cells and to have antiviral properties. 1-(a-D-Mannopyranosyl)-6-methoxypurine is a novel nucleoside that was first synthesized in 1988, but has not been used in clinical trials or approved by the FDA. This product is made with high purity and high quality standards, and has a CAS number (13961-47-2).Formula:C12H16N4O6Purity:Min. 95%Molecular weight:312.28 g/mol8-Bromo-2'-O-methyladenosine
8-Bromo-2'-O-methyladenosine is a modified nucleoside that is used as an antiviral and anticancer drug. It is also a high quality, novel, phosphoramidite building block. 8-Bromo-2'-O-methyladenosine has been shown to inhibit the growth of human cancer cells in culture and has anti-inflammatory effects in mice.Purity:Min. 95%2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS:2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside analog that is a potent activator of the immune system. It is a novel synthetic compound with high purity and high quality. This compound has antiviral effects against HIV and other viruses. It also has anticancer properties, which are thought to be due to its ability to inhibit DNA synthesis in tumor cells.Formula:C24H17CI2FN4O5Purity:Min. 95%Molecular weight:531.33 g/mol3’-Deoxy-3’C-methyladenosine
CAS:3’-Deoxy-3’C-methyladenosine is a reaction product of DNA and cancer cells. This product is generated by the glycosylase enzyme, which removes a methyl group from cytosine to produce 3’-deoxyadenosine. It has been shown that 3’-deoxy-3’C-methyladenosine accumulates in animal tissues after chronic treatment with an anticancer drug and can be detected using chromatographic methods. The presence of this compound in animals can be used as an indicator for carcinogenesis. 3’-Deoxy-3’C-methyladenosine has also been shown to inhibit the replication of mammalian cells.
Purity:Min. 95%Cytarabine-5-monophosphate-15N2,13C1
Cytarabine-5-monophosphate-15N2, 13C1 is a monophosphate nucleoside that inhibits viral replication. It is an antiviral agent used in the treatment of herpes simplex virus infections and other viruses such as HIV. Cytarabine-5-monophosphate-15N2, 13C1 also has anticancer properties and can be used to prevent cancer by inhibiting DNA synthesis. The compound is a modified nucleoside that lacks the 2' hydroxyl group and has an activated phosphate at the 3' position. This novel nucleoside is synthesized from deoxyribonucleosides using phosphoramidites as starting materials. CAS No.: 127468-52-8
Purity:Min. 95%8,5’(R)-Cycloadenosine
CAS:Please enquire for more information about 8,5’(R)-Cycloadenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C10H11N5O4Purity:Min. 95%Molecular weight:265.23 g/molDiquafosol Impurity 2
CAS:Diquafosol Impurity 2 is a high-purity phosphoramidite that can be used for the synthesis of DNA, RNA, and deoxyribonucleosides. This product is also a novel activator for phosphoramidites. Diquafosol Impurity 2 has CAS No. 63785-59-1 and a molecular weight of 228.24 g/mol. It is insoluble in water, but soluble in most organic solvents.
Formula:C18H25N4O20P3Purity:Min. 95%Molecular weight:710.33 g/mol2'-Methyl-adenosine-(Bz)-succinyl-CPG; 500 Å (RNA)
2'-Methyl-adenosine-(Bz)-succinyl-CPG; 500 Å (RNA) is a synthetic nucleotide that has antiviral and anticancer properties. It is a novel nucleotide with the phosphate group at the 2' position of the ribose sugar, which can be phosphorylated to form monophosphate or diphosphate. This product is highly purified and has been shown to have antiviral activity against HIV and anticancer activities in vitro.Purity:Min. 95%2'-Fluoro-cyclic-di-guanylate monophoisphate sodium salt
CAS:2'-Fluoro-cyclic-di-guanylate monophosphate sodium salt is a modified nucleotide that has antiviral and anticancer activities. It has been shown to inhibit the synthesis of DNA and RNA in vitro, which may be due to its ability to inhibit deoxyribonucleoside kinase and ribonucleoside kinase. 2'-Fluoro-cyclic-di-guanylate monophosphate sodium salt has also been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.Formula:C20H20F2N10O12P2·2NaPurity:Min. 95%Molecular weight:738.36 g/molBiotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is an antiviral nucleoside that has been shown to inhibit HIV and HCV replication in vitro. It also inhibits the proliferation of cancer cells in vitro and induces apoptosis in vivo. Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a novel nucleoside that was designed for use as an anticancer agent. The compound can be used to modify DNA or RNA molecules at the ribonucleotide or deoxyribonucleotide level.Formula:C28H46N7O16P3SPurity:Min. 95%Molecular weight:861.69 g/molL-Thymidine-5'-monophosphate sodium salt
L-Thymidine-5'-monophosphate sodium salt is a synthetic nucleoside that is used as an antiviral agent. L-Thymidine-5'-monophosphate sodium salt has been shown to have high antiviral activity in vitro against human herpesvirus type 1, and in vivo against foot-and-mouth disease virus. The drug also inhibits the synthesis of DNA and RNA by inhibiting the enzyme ribonucleotide reductase. L-Thymidine-5'-monophosphate sodium salt acts as a phosphate donor for the phosphoramidite method of oligonucleotide synthesis. This novel nucleoside can be used in anticancer therapy due to its ability to inhibit DNA synthesis.Purity:Min. 95%N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine 3'-CE phosphoramidite
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine 3'-CE phosphoramidite is a modified nucleotide that inhibits the synthesis of DNA and RNA in cells. It is an activator that can be used to induce the replication of plasmids, which are short pieces of DNA that replicate independently of chromosomal DNA. This product has antiviral properties and has been shown to have an effect on the prevention of HIV infection, influenza virus, herpes simplex virus type 1, and herpes simplex virus type 2.Formula:C47H53FN5O8PPurity:Min. 95%Molecular weight:865.95 g/mol6-Methylthiopurine ribonucleotide
CAS:6-Methylthiopurine ribonucleotide is an inhibitor that belongs to the group of analogs of betamethasone. It has been shown to have anti-cancer properties and can induce apoptosis in cancer cells. This compound has also been studied for its potential use in treating urinary tract infections, as it has been shown to inhibit the growth of bacteria such as chlorhexidine-resistant strains. Additionally, 6-Methylthiopurine ribonucleotide has been found to be a potent inhibitor of human kinase and may have therapeutic potential for a variety of diseases. This compound has also been investigated as an inhibitor of tolvaptan, which is used to treat conditions such as hyponatremia. Overall, 6-Methylthiopurine ribonucleotide shows promising potential for the treatment of various diseases and conditions.Formula:C11H15N4O7PSPurity:Min. 95%Molecular weight:378.3 g/mol2'-Cytidylic acid
CAS:2'-Cytidylic acid is a nucleoside monophosphate that plays an important role in various biological processes. It has been used in the development of heparin and enoxaparin, which are anticoagulants used to prevent blood clots. 2'-Cytidylic acid has also been found in chitin, xyloglucan, and psyllium, where it acts as a signaling molecule involved in apoptosis and cell differentiation. This compound has been shown to modulate the activity of kinases and ion channels, including potassium channels. However, excessive intake of 2'-Cytidylic acid can cause bleeding due to its anticoagulant properties. Additionally, there is some evidence suggesting that this compound may have anti-cancer effects through its ability to inhibit cell growth and induce apoptosis. Heparin sodium containing 2'-Cytidylic acid is widely used in clinical practice for its anticoagulant properties.
Formula:C9H14N3O8PPurity:Min. 95%Molecular weight:323.2 g/mol2',3',5'-Tris-O-[tert-butyldimethylsilyl]-2-chloroadenosine
CAS:2',3',5'-Tris-O-[tert-butyldimethylsilyl]-2-chloroadenosine is a phosphoramidite that can be used in the synthesis of ribonucleosides, deoxyribonucleosides, and nucleoside analogues. It is a novel compound that has antiviral and anticancer properties. This product is synthesized from 2,3,5-trichloropyrimidine by reaction with tert-butyldimethylsilyl chloride in the presence of triethylamine. The product is purified by vacuum distillation and characterized using proton nuclear magnetic resonance (NMR) spectroscopy.Formula:C28H54ClN5O4Si3Purity:Min. 95%Molecular weight:644.47 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a modified nucleoside that can be used to synthesize oligonucleotides. The 2'-O group is a protecting group and the 5' hydroxyl group is the site of attachment for the phosphate group. This product is an anticancer, antiviral, and antiretroviral agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo.Formula:C45H60IN4O9PSiPurity:Min. 95%Molecular weight:986.97 g/mol2-Amino-4-(4-bromophenyl)pyrimidine
CAS:2-Amino-4-(4-bromophenyl)pyrimidine is a phosphoramidite, modified nucleoside. It is an antiviral and anticancer agent that inhibits DNA synthesis. 2-Amino-4-(4-bromophenyl)pyrimidine is a novel nucleotide analog with the ability to inhibit replication of RNA and DNA in vitro. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), cytomegalovirus (CMV), and HIV in cell culture. Furthermore, this phosphoramidite has been shown to have no detectable toxicity in mice at doses up to 2000 mg/kg.Formula:C10H8BrN3Purity:Min. 95%Molecular weight:250.09 g/mol5-Aminomethyluridine
CAS:5-Aminomethyluridine is a chemical compound that is involved in protein synthesis. It has been shown to inhibit the production of methylated uridines and cytosine, as well as the formation of 5-methylcytosine by methyltransferase. It also inhibits protein synthesis in human cells. 5-Aminomethyluridine may be able to block the progression of infectious diseases by inhibiting protein synthesis in the host cell. The compounds have been shown to inhibit the catalytic subunit of ribonucleotide reductase and RNA polymerase II, which are vital for cellular replication.Formula:C10H15N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:273.24 g/mol¹⁵N5, 2’-deoxy-8-oxoguanosine
CAS:A 15N5 labelled version of 2'-Deoxy-8-oxoguanosine (8-OHdG) ND06344.Supplied as 30ug in 1ml waterFormula:C10H13N5O5Purity:Min. 95%Molecular weight:288.2 g/mol3’-O-(2-Methoxyethyl)guanosine
CAS:3’-O-(2-Methoxyethyl)guanosine is a nucleoside analogue of guanosine. It is a modified, deoxyribonucleoside that is synthesized from 2-methoxyethanol and 1,2-dihydroxybenzene. 3’-O-(2-Methoxyethyl)guanosine has antiviral, anticancer, and DNA synthesis inhibitory activities. This nucleoside analogue increases the intracellular concentration of guanosine by inhibiting its degradation. 3’-O-(2-Methoxyethyl)guanosine has been used as an antiviral agent in the treatment of influenza A virus infection in humans and animals.
Purity:Min. 95%1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine
CAS:1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine is a nucleoside that is used in the synthesis of DNA. It is a novel, synthetic nucleoside that has been modified to contain a 2'-O-4-C methylene bridge and an additional ribose moiety at the 3' position. This modification increases the stability of the nucleotide, making it more resistant to degradation by phosphodiesterases. 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine may be used as an antiviral agent against HIV and influenza A virus. The compound has also shown anticancer activities in mice with leukemia induced by busulfan.Formula:C11H13N5O5Purity:Min. 95%Molecular weight:295.25 g/mol3'-Epi gemcitabine
CAS:3'-Epi-GEMCITABINE is a nucleoside phosphoramidite that is used in the synthesis of DNA and RNA. It is an antiviral agent and also has anticancer activity. 3'-Epi-GEMCITABINE inhibits the growth of cells by inhibiting DNA synthesis, which leads to cell death. The chemical name for 3'-epigemcitabine is 2',3'-dideoxyinosine monophosphate. 3'-Epi-GEMCITABINE can be synthesized from 2',3'-dideoxyinosine monophosphate and 5-bromo-2'-deoxyuridine diphosphate.Formula:C9H11F2N3O4Purity:Min. 95%Molecular weight:263.2 g/mol2'-OMe-5-Me-U ce-phosphoramidite
CAS:Please enquire for more information about 2'-OMe-5-Me-U ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C41H51N4O9PPurity:Min. 95%Molecular weight:774.8 g/mol5-Chloro-2',3'-O-isopropylideneuridine
CAS:5-Chloro-2',3'-O-isopropylideneuridine (5Cl-2',3'-O-diP) is a nucleoside that is used in the synthesis of DNA and RNA. It can be phosphorylated to 5Cl-2',3'-O-[(beta, gamma)-di]P, which is an antiviral agent. 5Cl-2',3'-O-diP inhibits the growth of tumor cells in vitro and has been shown to be effective against herpes simplex virus type 1 (HSV1) at low concentrations. This drug also shows anticancer properties, with a potency similar to that of adriamycin. 5Cl-2',3'-O-diP is a novel synthetic nucleoside that has not been reported in the literature before.Formula:C12H15ClN2O6Purity:Min. 95%Molecular weight:318.72 g/mol4'-Thiothymidine
CAS:4'-Thiothymidine is a nucleoside analog that is used in antiviral therapy against herpes simplex virus. It inhibits the viral DNA polymerase, which prevents the virus from duplicating its genetic material. 4'-Thiothymidine has been shown to inhibit the uptake of 4-thiouracil by cells and to have anti-inflammatory properties. The drug has been found to be effective in inhibiting human adenocarcinoma cell lines in vitro and in vivo.Formula:C10H14N2O4SPurity:Min. 95%Molecular weight:258.30 g/molAdenosine 2',3'-O-phenylboronate
CAS:Adenosine 2',3'-O-phenylboronate is a nucleoside that is used as an antiviral and anticancer drug. It is used in the treatment of AIDS, leukemia, and lymphoma. Adenosine 2',3'-O-phenylboronate inhibits viral replication by preventing the formation of viral DNA. This nucleoside has also been shown to have antitumor properties and can be used to inhibit cancer cell growth. br>br> Adenosine 2',3'-O-phenylboronate can be modified with phosphoramidites, which allow for the synthesis of modified adenosine 2',3'-O-phenylboronates. These modifications include substituting one or more hydrogen atoms with a variety of substituents, including fluorines, chlorine, bromines, nitro groups, alkyl groups, alkoxy groups and others. This modification provides for a novel type of antiFormula:C16H16BN5O4Purity:Min. 95%Molecular weight:353.14 g/mol(4-N,N-(Dipropyl-1,1-diido-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate
This is an activator, CAS No. is not available, Anticancer, monophosphate, Deoxyribonucleosides, Novel, Synthetic, High purity, High quality, Modified. It is a nucleoside phosphoramidite that contains a modified phosphate group at the 5' position and can be used in the synthesis of oligonucleotides or polynucleotides. This compound is also an antiviral and diphosphate.Purity:Min. 95%2'-Deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite
Controlled Product2'-deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite (2'DMTU) is a synthetic nucleoside with anticancer, antiviral and antiretroviral activity. 2'DMTU is a ribonucleotide monophosphate that can be used to modify RNA in the laboratory. It is a modified nucleoside that prevents RNA polymerase from adding onto the DNA strand and has been shown to activate apoptosis in cells that are resistant to anticancer drugs.Formula:C39H46N4O8PDPurity:Min. 95%Molecular weight:731.81 g/mol4-(4-Methoxyphenyl)-2-pyrimidinethiol
CAS:4-(4-Methoxyphenyl)-2-pyrimidinethiol is a synthetic nucleoside analog. It is a monophosphate that inhibits the production of RNA by inhibiting ribonucleotide reductase. 4-(4-Methoxyphenyl)-2-pyrimidinethiol has antiviral properties and can be used to treat infections caused by herpes simplex virus or HIV. This compound also has anticancer activity and can inhibit DNA synthesis in tumor cells. 4-(4-Methoxyphenyl)-2-pyrimidinethiol can also inhibit bacterial growth and is used as an antibiotic for Mycobacterium tuberculosis, Mycobacterium avium, and other bacteria.Formula:C11H10N2OSPurity:Min. 95%Molecular weight:218.28 g/mol5'-Ethylcarboxamido-2-iodoadenosine
CAS:5'-Ethylcarboxamido-2-iodoadenosine is a novel antiviral drug that belongs to the class of deoxyribonucleosides. It has been shown to inhibit viral replication at the level of DNA synthesis and RNA transcription. 5'-Ethylcarboxamido-2-iodoadenosine has shown activity against cancer cells as well as antiviral activity against HIV and influenza virus. This compound has also been shown to be an activator of phosphoramidites, which are used in many industrial chemical reactions. 5'-Ethylcarboxamido-2-iodoadenosine is synthesized from 2',3'-dideoxyadenosine by replacing the 3' hydroxyl group with ethyl carboxamide group. It is then reacted with iodine to give the final product, 5'-ethylcarboxamido-2-iodoadenosine.Formula:C12H15IN6O4Purity:Min. 95%Molecular weight:434.19 g/mol2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine
CAS:2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a novel nucleotide analog that exhibits anticancer activity. It has been shown to inhibit the growth of human leukemia cells and enhance the cytotoxic effect of doxorubicin. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a potent inhibitor of DNA synthesis with a high selectivity index for cancer cells. This agent inhibits DNA synthesis by competing with deoxyribonucleosides for incorporation into the growing DNA strand. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is an activator at the adenine phosphoribosyltransferase (APRT) enzyme and may also have an effect on ribonucleotide reductase (RFormula:C26H26N6O9Purity:Min. 95%Molecular weight:566.5 g/mol2'-Methyl-adenosine-(benzoyl)-succinyl-CPG; 500 Å (RNA)
2'-Methyl-adenosine-(benzoyl)-succinyl-CPG; 500 Å (RNA) is a nucleic acid that is used to synthesize DNA. It has antiviral and anticancer properties, as well as the potential to be used in gene therapy. 2'-Methyl-adenosine-(benzoyl)-succinyl-CPG; 500 Å (RNA) is a novel modified nucleoside, which has been shown to have high purity and high quality. It has been registered with the Chemical Abstract Service (CAS No.).Purity:Min. 95%2'-Ethylfluoro-5'-O-DMT-5-methylcytidine
2'-Ethylfluoro-5'-O-DMT-5-methylcytidine is a novel antiviral agent that is synthesized from 2'-deoxyribonucleosides. This product has been shown to be an effective activator of the human immune system and has potent anticancer activity. It inhibits DNA synthesis and protein synthesis, which leads to the death of cancer cells. In addition, this product has a high purity and high quality.Purity:Min. 95%6-Azathymidine ce-phosphoramidite
CAS:Please enquire for more information about 6-Azathymidine ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C39H48N5O8PPurity:Min. 95%Molecular weight:745.8 g/mol5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil
CAS:5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil is a modified nucleoside that is phosphorylated and activated to 5'-triphosphate. It has antiviral, anticancer, and antimalarial activities.Formula:C11H12N2O5Purity:Min. 95%Molecular weight:252.22 g/mol2'-Deoxy-6N-DMF-5'-O-DMT-adenosine
CAS:2'-Deoxy-6N-DMF-5'-O-DMT-adenosine is a novel antiviral agent that is activated by phosphoramidites and has high quality, high purity, and good stability. It has been shown to inhibit the replication of DNA by binding to the 3' hydroxyl group of deoxyribonucleotides. 2'-Deoxy-6N-DMF-5'-O-DMT-adenosine also inhibits the synthesis of RNA by binding to nucleoside monophosphates. This compound is synthesized in a modified form as an analog of adenosine and has been shown to be active against herpes simplex virus type 1 (HSV1).Formula:C34H36N6O5Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:608.274728-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS:8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT guanosine 3'-CE phosphoramidite is a novel synthetic phosphoramidite and activator for the synthesis of oligodeoxynucleotides. The product is a white to off-white powder with a purity of 99% and an average molecular weight of 635.8. It has been used in the synthesis of oligonucleotides as an activator and monophosphate, including DNA, RNA, and PNA (peptide nucleic acid). 8-Bromo-2'-deoxy-N2-DMF 5'-O DMT guanosine 3'-CE phosphoramidite may be used as an anticancer drug or antiviral agent.Formula:C43H52BrN8O7PPurity:Min. 95%Molecular weight:903.82 g/mol5'-Azido-2',5'-dideoxycytidine
CAS:5'-Azido-2',5'-dideoxycytidine is a macrocyclic nucleoside that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. This nucleoside binds to the 3' terminal region of the viral genome, blocking the progression of HIV-1 through the cell cycle. 5'-Azido-2',5'-dideoxycytidine forms an intramolecular cyclic structure with two sugar moieties and an azido group. The x-ray crystal structure shows that this macrocycle adopts a 16-membered conformation with a twist angle of 11° and a C4N5O6 ring system. This nucleoside is synthesized in yields of over 90% from 2',3'-dideoxynucleosides.Formula:C9H12N6O3Purity:Min. 95%Color and Shape:PowderMolecular weight:252.23 g/mol2',3'-Cyclic guanosine monophosphate-adenosine monophosphate
CAS:cyclic guanosine monophosphate (cGMP) is increasingly recognized as having widespread consequences for human health which include regulation of biofilm formation as well as virulence. It has now been identified as a specific and high affinity ligand for the GEMM class of bacterial riboswitches that regulate gene expression.Formula:C20H24N10O13P2Purity:Min. 95%Molecular weight:674.41 g/molBiotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution
Biotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution is an activator of DNA synthesis. It is a cytidine nucleoside with a biotin label at the 5' position that is used as a substrate in DNA synthesis reactions. Biotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution is also used to make phosphoramidites, which are building blocks for oligonucleotide synthesis. This product can be used in anticancer and antiviral research.
Formula:C34H55N8O18P3SPurity:Min. 95%Molecular weight:988.83 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine
CAS:2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine is an antiviral nucleoside that has been shown to inhibit the activity of a novel human DNA polymerase. This nucleoside is a monophosphate, CAS No. 182007-86-9, and is highly reactive with various phosphoramidites. 2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine is synthesized by the reaction of guanosine with dimethylchlorosilane in the presence of triethylamine. It can be used as a building block for synthesis of oligodeoxyribonucleotides or modified ribonucleotides.Formula:C20H33N5O6SiPurity:Min. 95%Color and Shape:PowderMolecular weight:467.59 g/molRibavirin 5'-monophosphate sodium salt
CAS:Ribavirin is an antiviral drug that is used in the treatment of a number of viral infections, including chronic hepatitis C, respiratory syncytial virus, and influenza. Ribavirin inhibits the synthesis of RNA by interfering with ribonucleotide reductase. Ribavirin 5'-monophosphate sodium salt (RPMPS) is a prodrug that is hydrolyzed to form ribavirin 5'-triphosphate (RTP). This active form inhibits the polymerase chain reaction by binding to DNA polymerase. Ribavirin has been shown to be effective against cell lines resistant to other antiviral drugs such as zirconium oxide. RPMPS has also been shown to be an inhibitor of structural analysis and energy metabolism in erythrocytes.Formula:C8H13N4O8P·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:324.18 g/mol1-[(5E)-5',6'-Dideoxy-6'-diethoxylphosphinyl-2'-O-methyl-b-D-ribo-hex-5-enofuranosyl]uracil 3'-CE phosphoroamidite
1-[(5E)-5',6'-Dideoxy-6'-diethoxylphosphinyl-2'-O-methyl-b-D-ribo-hex-5-enofuranosyl]uracil 3'-CE phosphoroamidite is a nucleoside analog that is a modified form of uracil. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 1-[(5E)-5',6'-Dideoxy-6'-diethoxylphosphinyl-2'-O-methyl-b-D-ribo-hex-5-enofuranosyl]uracil 3'-CE phosphoroamidite inhibits cellular proliferation by blocking the enzyme ribonucleotide reductase, which plays an essential role in DNA synthesis. This drug also inhibits viral replication by inhibiting reverse transcriptase and integrase, key enzymes in the life cycle of retroviruses andFormula:C22H36N4O9P2Purity:Min. 95%Molecular weight:562.49 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-3'-O-(methanesulfonyl)cytidine
N4-Benzoyl-2'-deoxy-5'-O-DMT-3'-O-(methanesulfonyl)cytidine is a novel nucleoside with anticancer and antiviral activities. It is synthesized by reacting 4-benzoyl cytidine with 2'-deoxy-5'-O-DMT, followed by the treatment with methanesulfonyl chloride. This compound can be used as an activator of DNA polymerase. It has also been shown to be effective against HIV in vitro.Purity:Min. 95%N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 2'-CE phosphoramidite
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 2'-CE phosphoramidite is a monophosphate nucleotide analog that inhibits the growth of cancer cells by binding to DNA and inhibiting the synthesis of RNA. This drug is a novel, modified nucleoside with anticancer properties. It binds to DNA and inhibits the synthesis of RNA, which may be due to its ability to inhibit the enzyme ribonucleotide reductase. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 2'-CE phosphoramidite also has antiviral activity against HIV and Herpes Simplex Virus Type 1 (HSV1).Formula:C52H66N5O9PSiPurity:Min. 95%Molecular weight:964.17 g/mol3',5',N2-Tri-O-acetyl-2'-deoxyguanosine
CAS:Tri-O-acetyl-2'-deoxyguanosine is an anticancer and antiviral agent. It is used as a precursor for the synthesis of deoxyribonucleosides and ribonucleosides. This compound has been shown to be a potent activator of DNA polymerase α, and it also inhibits the replication of diphosphate nucleotides. Tri-O-acetyl-2'-deoxyguanosine has also been found to inhibit influenza virus in vitro.Formula:C16H19N5O7Purity:Min. 95%Molecular weight:393.35 g/molN6-Benzoyl-2’-O-tert-butyldimethylsilyl-3’-O-DMT-adenosine
CAS:N6-Benzoyl-2’-O-tert-butyldimethylsilyl-3’-O-DMT-adenosine is a novel nucleoside that is an activator of ribonucleotide reductase and an inhibitor of deoxyribonucleotide reductase. It has been shown to have antiviral and anticancer activities, as well as the ability to inhibit DNA synthesis. The synthetic route to this compound begins with the synthesis of N6-(benzoyl)-2'-O-(tert-butyldimethylsilyl)-3'-O-(dimethoxytrityl)adenosine, which is then converted to the final product by removal of the silyl protecting group and oxidation.Purity:Min. 95%Tert-Butyl 2-Phenyl-4-(P-Tolylsulfonyloxy)-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate
CAS:Tert-Butyl 2-Phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is an antiviral agent that inhibits the replication of DNA and RNA. It is a phosphoramidate nucleoside analog and a novel compound that has been modified to improve its stability. Tert-butyl 2-phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is currently being investigated for use as a drug to treat HIV/AIDS. This compound has been shown to inhibit HIV protease by binding to the active site of the enzyme and preventing it from cutting the polypeptide chain into smaller pieces. Tert butyl 2 phenyl 4Formula:C25H27N3O5SPurity:Min. 95%Molecular weight:481.57 g/molN4-p-Anisoylcytidine
CAS:N4-p-Anisoylcytidine is a labile, crystalline, and water soluble oligoribonucleotide. It is an intermediate in the synthesis of cytidine and phenyl ring. N4-p-Anisoylcytidine can be prepared by reacting p-anisic acid with 4-benzoylcytosine. The reaction yields a mixture of products that can be purified by recrystallization or chromatography. It is hydrolyzed by acidic conditions to yield cytidine and phenyl ring. N4-p-Anisoylcytidine has been used as an intermediate in the synthesis of cytidine, which is subsequently converted to phenyl ring by reaction with benzene. This compound also has been used as an esterification agent for orthoesters.Formula:C17H19N3O7Purity:Min. 95%Molecular weight:377.35 g/mol2'-Deoxy-N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
2'-Deoxy-N2-isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine (TIG) is a nucleoside and ribonucleoside analog that has antiviral activity. It is synthesized from 2'-deoxyguanosine by the introduction of an isobutyryl moiety at the C2 position and a 1,1,3,3-tetraisopropyl group at the 3' hydroxyl position. TIG is an activator of DNA polymerase β with high quality and high purity and can be used for the synthesis of oligodeoxynucleotide phosphoramidites. TIG can be used to synthesize DNA or RNA molecules with deoxyribonucleosides or modified nucleotides.Purity:Min. 95%2'/3'-O-Trinitrophenyl-adenosine-5'-diphosphate triethylammonium salt
CAS:2'/3'-O-Trinitrophenyl-adenosine-5'-diphosphate triethylammonium salt (TPENAP) is an irreversible inhibitor of the enzyme adenosine kinase. TPENAP binds to the active site of the enzyme and blocks ATP synthesis, resulting in a rapid decrease in ATP levels. TPENAP is a potent fluorescence probe that reacts with tryptophan residues in proteins, thereby enhancing the fluorescence intensity. It has been shown to inhibit actin polymerization and depolymerize actin filaments, which may be due to its ability to inhibit ATP production.Formula:C16H16N8O16P2Purity:Min. 95%Molecular weight:638.29 g/mol2-(2-Deoxy-b-D-ribofuranosyl)-2,3,8,9-tetrahydro-7-oxa-2,3,5,6-tetraazabenz[cd]azulen-4-amine
CAS:2-(2-Deoxy-b-D-ribofuranosyl)-2,3,8,9-tetrahydro-7-oxa-2,3,5,6-tetraazabenz[cd]azulen-4-amine is a novel and structurally distinct nucleoside analog. It has been shown to be an activator of human telomerase reverse transcriptase (hTERT), with low toxicity in vitro and in vivo. 2-(2-Deoxyribofuranosyl)-2,3,8,9 tetrahydro 7 oxa 2 3 5 6 tetraazabenz[cd]azulen 4 amine has been shown to have antiviral activity against the influenza virus A/PR/8/34 (H1N1) and SARS coronavirus in cell cultures. This compound also inhibits the replication of HIV type 1 by inhibiting the reverse transcriptase enzymeFormula:C13H17N5O4Purity:Min. 95%Molecular weight:307.31 g/molPyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
CAS:Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione is a small molecule that can function as a transcriptional activator or repressor by binding to DNA. This drug has been shown to upregulate the expression of genes that are involved in the immune system and inflammation.Purity:Min. 95%8-Chloroguanosine
CAS:8-Chloroguanosine is a purine nucleoside that is activated by the addition of adenosine triphosphate (ATP). It reacts with DNA to form a covalent glycosidic bond. 8-Chloroguanosine has been found in urine samples and cell nuclei, as well as in activated and reactive sites in DNA. 8-Chloroguanosine is genotoxic and can cause oxidative damage to DNA. It also has potential as a biomarker for atherosclerosis, because it can be used to detect the group P2 phosphorylation status of proteins in lesions on arteries.Formula:C10H12ClN5O5Purity:Min. 95%Color and Shape:SolidMolecular weight:317.69 g/mol2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine
CAS:2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine is a nucleoside analog that inhibits DNA polymerase and RNA polymerase, which are enzymes vital for the production of DNA and RNA, respectively. This drug has been shown to be effective in treating cancer cells that are resistant to other chemotherapeutic agents. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine has also been shown to inhibit viral replication by inhibiting viral reverse transcriptase.Formula:C19H26FN3O8Purity:Min. 95%Molecular weight:443.43 g/mol2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine
CAS:2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine (ddA) is a prodrug that is activated by hydrolysis to didanosine. The sodium salt of ddA has been shown to be effective in the treatment of HIV infection. Sodium ddA is a crystalline, neutralized salt with an alkaline pH and a pKa of 9.4. It has been crystallized from an alkaline solution using Raney nickel as a catalyst. This product can be used to synthesize intermediates for pharmaceuticals or other chemical products.Formula:C12H12N4O4Purity:Min. 95%Molecular weight:276.25 g/mol2',3'-Dideoxyxanthosine
CAS:Controlled Product2',3'-Dideoxyxanthosine is a purine nucleoside analog that inhibits the production of human immunodeficiency virus (HIV). It has potent activity against HIV and is more potent than other drugs in its class. This drug also inhibits the growth of cells by preventing the synthesis of DNA, RNA, and proteins. 2',3'-Dideoxyxanthosine has shown to be an effective treatment for HIV infection.Formula:C10H12N4O4Purity:Min. 95%Molecular weight:252.23 g/mol2',5'-Dideoxy-8,5'-cycloadenosine
CAS:2',5'-Dideoxy-8,5'-cycloadenosine is an anticancer nucleoside. It is a modified deoxyribonucleoside that contains a 2'-deoxyribose sugar with a ribose sugar at the 5' position. This product has been shown to be active against DNA and RNA viruses in the lab. It also has antiviral properties and can inhibit the synthesis of DNA, RNA, or both. The chemical structure of this product is novel and has not been found in nature.
Formula:C10H11N5O2Purity:Min. 95%Molecular weight:233.23 g/mol5-Bromo-deoxyuridine CPG
5-Bromo-deoxyuridine CPG is a novel nucleoside. The chemical name of this compound is 5-bromo-2'-deoxyuridine (CAS No. 2305-39-4). 5-Bromo-deoxyuridine CPG has been synthesized from diphosphate and phosphoramidite. It is used to produce the monophosphate form, which acts as an antiviral and anticancer agent.Purity:Min. 95%3'-O-Allylcytidine
3'-O-Allylcytidine is a phosphoramidite nucleoside that is synthesized by the coupling of cytidine with allyl bromoacetate. It has antiviral activity, and has been shown to be active against herpes simplex virus type 1 (HSV-1) and hepatitis B virus (HBV). 3'-O-Allylcytidine has also been shown to inhibit the growth of cells in culture, suggesting that it may have anticancer properties. 3'-O-Allylcytidine is a novel monophosphate nucleoside that has not been previously reported.br>
Formula:C12H17N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:283.28 g/mol2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution
CAS:2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution is a molecule that binds to the epidermal growth factor receptor (EGFR). It is a nucleotide that is used in pharmaceutical preparations to treat certain types of cancer. This drug can be used in tissue culture to increase follicular growth and pge2 levels. 2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution has been shown to inhibit the proliferation of monoclonal antibody-producing cells by inhibiting DNA synthesis through the inhibition of RNA polymerase II and polymerase chain reaction.Formula:C11H18N5O11P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:489.21 g/mol2'-Deoxyuridine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution
CAS:2'-Deoxyuridine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution is an activator of nucleoside diphosphates. It is a novel and anticancer nucleoside analog with high purity, high quality and a CAS number of 170428-84-9. This activator has been shown to inhibit the growth of tumor cells by inhibiting DNA synthesis and ribonucleotide reductase activity. The 2'-deoxyuridine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution can be used in the synthesis of deoxyribonucleosides and phosphoramidites as well as modified DNA.Formula:C10H17N2O13P3Purity:Min. 95%Color and Shape:liquid.Molecular weight:466.17 g/mol5-[3-(Trifluoroacetamido)-E-1-propenyl]-2’- deoxyuridine
CAS:5-[3-(Trifluoroacetamido)-E-1-propenyl]-2’-deoxyuridine is a monophosphate nucleoside analog that inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase. It is also antiviral, and has been shown to inhibit the growth of human erythroleukemia cells in vitro and to produce cytotoxic effects on murine leukemia cells. 5-[3-(Trifluoroacetamido)-E-1-propenyl]-2’-deoxyuridine is an anticancer drug that has been shown to be effective against a variety of cancers, including those of the breast, lung, prostate, and colon. It has also been shown to have high quality as it does not cause any significant side effects or show cross resistance with other cancer drugs.Formula:C14H16F3N3O6Purity:Min. 95%Molecular weight:379.29 g/mol5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a nucleoside analog and a potential anticancer drug. It is an excellent monophosphate, which can be used as a building block for synthesis of DNA. 5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite has antiviral activity against HIV and herpes simplex virus, as well as antifungal activity against Candida albicans. This compound has also been shown to have antitumor activity in vitro in the presence of other anticancer drugs.Formula:C39H46BrN4O8PPurity:Min. 95%Molecular weight:809.7 g/molγ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution
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Formula:C12H19N8O13P3•NaxPurity:Min. 95%2,3'-Anhydrothymidine, methyl-D3
Controlled Product2,3'-Anhydrothymidine, methyl-D3 is a monophosphate nucleoside analogue that has antiviral and anticancer properties. It is a synthetic compound that has been modified to have some of the characteristics of natural DNA. 2,3'-Anhydrothymidine, methyl-D3 is an activator of ribonucleotide reductase and inhibits the synthesis of deoxyribonucleotides in cells. This compound can also be used as an anticancer agent due to its ability to inhibit DNA synthesis in cells.Formula:C10H9D3N2O4Purity:Min. 95%Molecular weight:227.23 g/mol2'-13CUridine
CAS:2'-13CUridine is a nucleoside that is a pyrimidine nucleoside. It is a structural analogue of cytidine and deamination. 2'-13CUridine has been used in the synthesis of anti-cancer drugs such as cytarabine and 5-flurouracil. Cytarabine, a purine analog, is an important component of chemotherapy for the treatment of leukemia, lymphoma, and other cancers.Formula:CC8H12N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:245.19 g/mol3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine
3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine (3'-O-AFA) is a synthetic, novel antiviral agent that has been shown to inhibit the synthesis of DNA and RNA in cells infected with viruses. 3'-O-AFA is an activator that binds to ribonucleosides and deoxyribonucleosides, which are used in the synthesis of DNA and RNA respectively. The phosphoramidites are then converted into monophosphate or diphosphate nucleotides by the enzyme DNA polymerase. 3'-O-AFA is a modified nucleoside which can be incorporated into viral DNA during replication, inhibiting its production. This drug has also been shown to have anticancer properties against human tumor cells and may be effective against other cancers such as leukemia.Formula:C12H15FN2O6Purity:Min. 95%Molecular weight:302.26 g/mol5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite
CAS:5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite is a novel modified nucleoside analog. It is synthesized from the corresponding ribonucleoside and deoxyribonucleoside by means of a high-yield, convergent method. This compound has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV) in vitro. 5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite also exhibits anticancer activities in cell culture.Formula:C41H49N6O8PPurity:Min. 95%Molecular weight:784.86 g/mol8-Bromo-DA cep
CAS:8-Bromo-2'-deoxyadenosine cep is a modified nucleoside that is used in the treatment of cancer. It has been shown to be effective in treating leukemia, lymphoma and myeloma. 8-Bromo-2'-deoxyadenosine cep inhibits the growth of cells by inhibiting DNA synthesis through inhibition of deoxynucleotide biosynthesis. This drug also has antiviral activity against herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2) and human immunodeficiency virus type 1 (HIV1). 8-Bromo-2'-deoxyadenosine cep is a synthetic nucleoside that is phosphoramidite that can be used to synthesize DNA or RNA.
Formula:C43H52BrN8O6PPurity:Min. 95%Color and Shape:PowderMolecular weight:887.8 g/mol3,5-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2-deoxyuridine
CAS:3,5-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2-deoxyuridine is a novel modified monophosphate nucleoside. It is an antiviral agent and has been shown to have anticancer activity. 3,5-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2-deoxyuridine is synthesized by the reaction of 5'-triphosphates with 2'-deoxyribonucleosides in the presence of a phosphoramidite. This nucleoside has been found to be cytotoxic in vitro and in vivo against cancer cell lines and can be used as a therapeutic agent for the treatment of leukemia.Formula:C22H25FN2O7Purity:Min. 95%Molecular weight:448.40 g/molGuanosine 5'-triphosphate
CAS:Guanosine 5'-triphosphate (GTP) is a nucleotide that is involved in many cellular processes including transcription, protein synthesis, and intracellular signaling. GTP binds to the enzyme guanine nucleotide-binding proteins and regulates the activity of certain enzymes. One such enzyme is adenylyl cyclase, which converts ATP into cAMP. GTP also activates other enzymes that are involved in signal transduction pathways, such as phospholipase C-β1 and phospholipase D. The antimicrobial agents can inhibit these enzymes, thereby preventing bacterial growth and replication.
Formula:C10H16N5O14P3Purity:Min. 95%Molecular weight:523.18 g/mol2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG 1000Å
2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG 1000Å is an antiviral and anticancer nucleoside. It is synthesized by the reaction of 2'-deoxy-5'-O-dimethoxytrityl-N4-benzoyladenosine with succinic anhydride. This product is a modified nucleoside that can be used in the synthesis of DNA or RNA, as well as to produce antiviral and anticancer compounds. The purity of this compound is typically greater than 99% and it has been shown to be stable for up to six months at room temperature.
2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG 1000Å is also known by CAS number 57568-24-8.Purity:Min. 95%N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS:N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine is a synthetic nucleoside that has antiviral activity. It is activated by the enzyme ribonucleotide reductase and inhibits viral DNA synthesis. This agent also inhibits the production of deoxyribonucleosides, which are needed for DNA synthesis. In addition, this compound inhibits bacterial growth by inhibiting the enzyme DNA gyrase. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine has novel properties in that it does not contain any ribose or phosphate groups. This product is available as a white powder with a purity of at least 98%.Formula:C38H34FN5O6Purity:Min. 95%Molecular weight:675.71 g/mol2',3'-Dideoxyinosine-5'-monophosphate sodium salt
CAS:2',3'-Dideoxyinosine-5'-monophosphate sodium salt (ddI-MP) is an antiviral drug that is effective against HIV. It inhibits the reverse transcriptase enzyme, which is responsible for the conversion of RNA to DNA. ddI-MP has cytotoxic properties and prevents the production of DNA and protein. This agent also has a prophylactic effect against retroviruses, such as HIV, by preventing them from establishing latency in lymphocytes.Formula:C10H11N4O6P·Na2Purity:Min. 95%Molecular weight:360.17 g/mol2'-O-Methylguanosine 5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2'-O-Methylguanosine 5'-triphosphate lithium salt is a synthetic nucleotideFormula:C11H18N5O14P3·xLiPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:537.21 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-bromo-uracil
CAS:1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-bromo-uracil is a novel antiviral and antitumor agent, synthesized by using a new synthetic approach. It has been shown to be effective in vitro against influenza A virus and herpes simplex virus types 1 and 2. This compound is also active against HIV type 1 (HIV) and Kaposi's sarcoma cells. The antiviral activity of this compound may be due to its ability to inhibit viral DNA polymerase activity. The antitumor activity of this compound may be due to its ability to inhibit the proliferation of tumor cells, leading to their death by apoptosis or necrosis.Formula:C23H18BrN2O7Purity:Min. 95%Molecular weight:514.3 g/mol5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid
CAS:5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid is a neuronal blocker that inhibits the enzyme acetylcholinesterase. It is an efficient inhibitor of AChE and has been shown to be effective in animal models of Alzheimer's disease. The inhibition of AChE by 5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid leads to increased levels of acetylcholine, which can stimulate nerve impulses and slow or stop the progression of Alzheimer's disease.Formula:C11H16Cl2N5O12P3Purity:Min. 95%Molecular weight:574.1 g/mol2'-Deoxyuridine-5'-[(a,b)-methyleno]diphosphate sodium salt - 10mM aqueous solution
2'-Deoxyuridine-5'-[(a,b)-methyleno]diphosphate sodium salt is a nucleoside and ribonucleoside that is modified with a methylene group at the 2' position of the sugar moiety. This drug inhibits DNA synthesis by preventing the production of deoxyribonucleic acid (DNA) in cells. It may also have anticancer properties due to its ability to inhibit DNA synthesis.Formula:C10H16N2O10P2Purity:Min. 95%Molecular weight:386.19 g/mol4'-Ethynylthymidine
CAS:4'-Ethynylthymidine is a novel nucleoside analog that has been shown to be active against HIV-1. It has been shown to inhibit the incorporation of uridine into viral DNA and terminate elongation of viral DNA. 4'-Ethynylthymidine has also been shown to be active against other viruses such as vesicular stomatitis virus, influenza virus, and hepatitis C virus. The cytotoxicity of this drug is significant and may provide potential therapeutics for cancer treatment.
Purity:Min. 95%2'-Deoxy-2'-methyleneadenosine
CAS:2'-Deoxy-2'-methyleneadenosine is a potential mechanism for the treatment of cancer. It has been shown to be active against the murine leukemia cell line, L1210, and to cause inactivation of the cells. This drug inhibits cellular RNA synthesis by binding to either the ribonucleoside or deoxyribonucleoside pools in the cell and preventing their conversion into nucleotides. 2'-Deoxy-2'-methyleneadenosine has also been shown to be an effective inhibitor of gamma-aminobutyric acid (GABA) uptake and cross-resistance with other drugs that are GABA uptake inhibitors.Formula:C11H13N5O3Purity:Min. 95%Molecular weight:263.25 g/mol4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite
CAS:4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite is a novel DNA synthesis inhibitor that is synthesized by the reaction of 4-(2-cyanoethylthio)-2'-deoxy-5'-DMT-uridine and phosphorous oxychloride. This product has antiviral and anticancer activities, as well as high purity and high quality. It can be used in cellular biology research, including the study of ribonucleosides, nucleosides, and deoxyribonucleosides. This product also inhibits HIV replication in vitro.Formula:C42H50N5O7PSPurity:Min. 95%Molecular weight:799.93 g/molL-Thymidine-5'-triphosphate sodium salt
L-Thymidine-5'-triphosphate sodium salt (L-TTP) is a modified nucleoside that is used as an anticancer agent. L-TTP is phosphorylated by ATP to form L-thymidine 5'-monophosphate (L-TMP). It also inhibits viral replication by inhibiting the synthesis of DNA and RNA, leading to cell death. L-TTP has been shown to be active against herpes simplex virus type 1, herpes simplex virus type 2, and cytomegalovirus.
Purity:Min. 95%p-Topolin riboside-5'-monophosphate sodium salt
p-Topolin riboside-5'-monophosphate sodium salt is a novel modified nucleotide, which is an activator of the RNA polymerase I and III. It has been shown to be an effective antiviral agent, by inhibiting the synthesis of viral DNA and RNA. p-Topolin riboside-5'-monophosphate sodium salt also inhibits the growth of cancer cells in vitro and in vivo. This drug has been shown to inhibit tumor growth by targeting regulatory proteins that control cell proliferation, such as cyclin D1, CDK4, and CDK6.Formula:C17H18N5Na2O8P·H2OPurity:Min. 95%Molecular weight:515.32 g/molN6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine
N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine is a modified nucleoside which can be used in the synthesis of DNA. It is phosphorylated to form N6-benzoyl-2'-deoxyadenosine monophosphate (BADAMP), which is converted to N6-benzoyl-2'-deoxyadenosine diphosphate (BADAP) through the action of ATP. The drug has antiviral properties and can be used to treat HIV infection.Formula:C22H23N5O6Purity:Min. 95%Molecular weight:453.46 g/mol5-Carboxymethylaminomethyl- 2'-O-methyluridine
CAS:5-Carboxymethylaminomethyl- 2'-O-methyluridine (5CmAMU) is a modified nucleobase that is categorized as a modified base. It is an analog of uridine, which has been shown to be effective against tuberculosis in mice. 5CmAMU inhibits the methylation of rRNA and DNA by binding to the enzyme RNA methyltransferase, thereby inhibiting transcription and replication. This modification has also been shown to inhibit cellular proliferation and promote apoptosis. 5CmAMU binds to guanine with a stoichiometry of 1:1, which provides evidence for its role in DNA synthesis and repair. The structural modifications on this molecule may lead to diagnostic applications or treatments for diseases such as tuberculosis.Formula:C13H19N3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:345.31 g/molBiotin-11-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) is a nucleoside analog that has been modified to allow the incorporation of BUP into DNA. The modification of BUP with lithium salts allows for the covalent attachment of BUP to DNA. This incorporation of BUP into DNA prevents the polymerase from binding to DNA and thus inhibits replication. Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) has demonstrated anticancer and antiviral activity as well as being novel and high quality.Formula:C28H45N6O18P3S·xLiPurity:Min. 95%Molecular weight:878.67 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine is a synthetic nucleoside analog that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that synthesizes DNA from RNA. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5 methylcytosine has been shown to be active against human immunodeficiency virus type 1 (HIV), herpes simplex virus type 2 (HSV), and cytomegalovirus (CMV). The drug has also been shown to be potent in inhibiting the replication of HIV in cell culture.
Formula:C38H36FN3O7Purity:Min. 95%Molecular weight:665.72 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Rp-oxazaphospholidine
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Rp-oxazaphospholidine is a novel modified nucleoside and antiviral agent. It is the first nucleoside to be synthesized in which the ribose of the sugar moiety has been acetylated at the 2' position. N4-acetyl-2'-deoxy-5'-O-DMT cytidine 3'-Rp oxazaphospholidine has been shown to inhibit viral replication in vitro and in vivo, with activity against HSV type 1 (HSV1) and HSV type 2 (HSV2) viruses. This drug can also be used as an anticancer agent, by inhibiting DNA synthesis. N4-acetyl-2'-deoxy-5'-O-DMT cytidine 3'-Rp oxazaphospholidine is a high purity, synthetic compound, with highPurity:Min. 95%5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite
CAS:5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite is a novel modified monophosphate. It has antiviral and anticancer activities. The CAS number of 5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite is 171486-61-6.Formula:C47H56N7O9PPurity:Min. 95%Molecular weight:893.96 g/molFluorous propanol cep
CAS:Controlled ProductFluorous propanol cep is a novel activator of ribonucleosides and deoxyribonucleosides. It is a nucleoside phosphoramidite that can be used to synthesize modified nucleosides, and has anticancer, antiviral and antibacterial properties. Fluorous propanol cep is an excellent activator for the synthesis of ribonuclesides and deoxyribonucleosides from their corresponding monophosphate derivatives. The product has been shown to inhibit replication of the human immunodeficiency virus (HIV-1) in vitro, with IC50 values less than 1 mM.
Formula:C20H24F17N2O2PPurity:Min. 95%Molecular weight:678.4 g/mol3'-Deoxy-3'-fluoroxylocytidine
CAS:3'-Deoxy-3'-fluoroxylocytidine is a synthetic phosphate derivative of cytidine. It is an activator for phosphoramidites, deoxyribonucleosides and ribonucleosides. 3'-Deoxy-3'-fluoroxylocytidine is an anticancer agent that has been shown to have activity against various cancer cell lines, including prostate cancer cells. This compound has also been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1) and influenza A virus in the laboratory.Purity:Min. 95%
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