Nucleosides

<p>3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine (3'-O-AFA) is a synthetic, novel antiviral agent that has been shown to inhibit the synthesis of DNA and RNA in cells infected with viruses. 3'-O-AFA is an activator that binds to ribonucleosides and deoxyribonucleosides, which are used in the synthesis of DNA and RNA respectively. The phosphoramidites are then converted into monophosphate or diphosphate nucleotides by the enzyme DNA polymerase. 3'-O-AFA is a modified nucleoside which can be incorporated into viral DNA during replication, inhibiting its production. This drug has also been shown to have anticancer properties against human tumor cells and may be effective against other cancers such as leukemia.</p>

<p>5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite is a novel modified nucleoside analog. It is synthesized from the corresponding ribonucleoside and deoxyribonucleoside by means of a high-yield, convergent method. This compound has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV) in vitro. 5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite also exhibits anticancer activities in cell culture.</p>

<p>1,2'-O-Dimethylguanosine is an activator of anticancer activity. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. 1,2'-O-Dimethylguanosine is a novel synthetic nucleoside analogue that can be modified to phosphoramidites and ribonucleosides for use as antiviral agents. This compound is also used as a building block for the synthesis of other nucleosides and nucleotides.</p>

<p>Octanoyl CoA is a molecule that belongs to the class of acyl-coenzyme A. It is an important intermediate in fatty acid metabolism and is also used in the synthesis of long-chain fatty acids. Octanoyl CoA can be converted back to acetyl-CoA by enzymes called synthetases, which are active in energy metabolism. Octanoyl CoA has been shown to have clinical relevance for diseases such as acyl chain disorders, carnitine deficiency, and dehydrogenase deficiency. Octanoyl CoA is a potential drug target since it can be converted into octanoic acid, which has been shown to inhibit enzyme activities and protein synthesis.</p>

<p>Lamivudine is an antiviral drug that is used as a nucleoside analogue. It is a prodrug that is converted to its active form, which inhibits the viral enzyme reverse transcriptase by interfering with the synthesis of viral DNA. Racemic lamivudine acid (LAM) crystallizes in the form of chains with hydrogen bonds oriented in an impurity plane. The LAM molecule has two substituents, one carboxylate and one oxathiolane group.</p>

<p>2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside analogue that inhibits the growth of cancer cells. It is used in the synthesis of oligonucleotides, which are used as drugs to treat cancers. This product has high purity and good quality and has been shown to be effective against cancer cells.</p>

<p>1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole is an anticancer drug that has been shown to inhibit tumor growth in vivo. This drug binds to the integrin receptor, which is expressed on the surface of cells and is involved in the process of cell adhesion. 1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole inhibits tumor growth by inhibiting hypoxic tumor formation. Hypoxia is a condition where there is not enough oxygen for normal cell function. This drug has also been shown to reduce inflammation, which may be due to its ability to inhibit proinflammatory cytokines, such as IL-1β and TNFα, from binding to their receptors on cells. 1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-</p>

<p>a-Nicotinamide adenine dinucleotide phosphate (NADP) is a modified form of the natural coenzyme nicotinamide adenine dinucleotide (NAD) and is an important component in cellular metabolism. NADP is also an anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It is used for the treatment of viral infections such as cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and Epstein-Barr virus (EBV). NADP is also a novel antiviral agent that has been shown to inhibit the enzyme diphosphate kinase, which prevents the production of ATP. This inhibition leads to cell death by disrupting normal energy production. NADP has been shown to be effective against CMV isolates resistant to ganciclovir or foscarnet due to its ability to inhibit DNA synthesis.</p>

<p>6-Methylcytidine is a nucleoside that is structurally related to uridine, which is an acceptor in DNA and RNA synthesis. It is synthesized from 8-bromoadenosine, which undergoes deamination by cytidine deaminase. 6-Methylcytidine can be used as a building block for the synthesis of other nucleosides with different conformational properties. It has been shown to inhibit the replication of pancreatic cancer cells and has been used in molecular modeling studies. However, its uptake into cells has been found to be very low. This may be due to its conformational properties and the presence of 8-oxoguanosine, which inhibits adenosine uptake into cells.</p>

<p>Please enquire for more information about 5'-ODMT cEt N-Bz A Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine is a synthetic nucleoside that has antiviral activity. It is activated by the enzyme ribonucleotide reductase and inhibits viral DNA synthesis. This agent also inhibits the production of deoxyribonucleosides, which are needed for DNA synthesis. In addition, this compound inhibits bacterial growth by inhibiting the enzyme DNA gyrase. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine has novel properties in that it does not contain any ribose or phosphate groups. This product is available as a white powder with a purity of at least 98%.</p>

<p>8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.</p>

<p>N,N-Dimethyl-2'-O-methylguanosine is a nucleoside that belongs to the category of nucleosides. It is a chemical structure that has been shown to have research value for the study of nucleic acids and their related diseases. This compound is also used in posttranscriptional mechanisms and phylogenetic studies. N,N-Dimethyl-2'-O-methylguanosine can be synthesized from uridine, ribonucleotide, or other nucleosides through various chemical reactions. It is also used as a structural component in some pharmaceuticals.</p>

<p>Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is a novel cytidine phosphoramidate monophosphate that has been shown to have anticancer and antiviral properties. It can be used as a DNA nucleoside phosphoramidite in the synthesis of oligonucleotides or as an antiviral agent by inhibiting viral RNA replication. Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is chemically synthesized in high purity and quality for use in research in the field of DNA, nucleosides, and antiviral agents.</p>

<p>2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside phosphoramidite that has antiviral and anticancer activity. This compound is a modified nucleoside that inhibits viral replication by inhibiting the synthesis of viral DNA. 2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetylbD ribofuranosyl)purine binds to the catalytic site of the enzyme ribonucleotide reductase, which is essential for the production of dNTPs. This chemical also has shown anticancer activity in cell culture against leukemia cells and breast cancer cells, although it was not active against colon cancer cells.</p>

<p>4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine is a novel nucleoside analogue that has high purity and high quality. It is an activator of DNA synthesis, diphosphate and monophosphate of deoxyribonucleosides, ribonucleosides and analogues. 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine has been shown to have antiviral activities against herpes simplex virus type 1 (HSV1) in cell culture.</p>

<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG is a nucleotide analog with antiviral and anticancer activity. It is considered to be a novel nucleoside analogue. It is synthesized by attaching an acetyl group to the 2' position of the adenosine moiety, which prevents phosphorylation by kinase enzymes. This inhibits DNA synthesis and induces apoptosis in cancer cells.</p>

<p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate is an analog of adenosine triphosphate (ATP). It inhibits the synthesis of RNA by binding to the ribonucleotide reductase enzyme. This inhibition leads to the inhibition of DNA synthesis, which in turn prevents cell division and/or causes cell death. The inhibitory effect of 2'-deoxy-2'-fluoroadenosine-5'-triphosphate on protein and DNA synthesis has been shown in vivo and in vitro using cell culture techniques. This compound inhibits topoisomerase II, a key enzyme in DNA replication, at high concentrations.</p>

<p>Dibutyryladenosine cyclic 3',5'-monophosphate (DBACMP) is a mitochondrial function regulator that inhibits the synthesis of ATP by binding to the methyltransferase enzyme. DBACMP also has an inhibitory effect on other enzymes, such as dna binding activity and enzyme activities involved in cellular energy metabolism. DBACMP inhibits infectious diseases by altering signal pathways, which leads to the production of cytokines and chemokines that have pro-inflammatory effects and stimulate axonal growth. The drug may also bind to the atp-binding cassette transporter and inhibit mitochondrial calcium uptake. DBACMP binds to polymorphonuclear leucocytes and alters cytosolic calcium levels, which may lead to an increased production of protein genes for cell growth.</p>

<p>2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt is an antiviral drug that inhibits viral DNA replication by inhibiting viral polymerase. It is a novel nucleoside analogue with antiviral activity against RNA viruses, including influenza virus and HIV. 2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt can be used as a precursor for the synthesis of modified monophosphate nucleosides, ribonucleosides and phosphoramidites. This product is supplied in high purity (98%) and high quality.</p>