Nucleosides

<p>3'-Deoxy-5'-O-DMT-3'-fluoro-thymidine (3'DFT) is a nucleoside that can be used as an anticancer drug. It is synthesized by the replacement of the 3'-hydroxyl group with a fluorine atom in 5'-O-DMT-3'-fluoro-thymidine. The synthesis of 3'DFT starts with the reaction of 5'O-(4,4'-dimethoxytrityl)-3'-deoxyuridine and 1,2,4,5-tetraisopropyldiazoacetate to form 5'O-(4,4'-dimethoxytrityl)-3'-deoxythymidine. This is followed by a reduction of the ester group to produce 5'O-(4,4'dimethoxytrityl)-3'F-thymidine. An acetate group is then added to</p>

<p>[(2R,3S,4R,5R)-5-(4-Benzamido-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4-fluoro-4-methyloxolan-2-yl]methyl benzoate is a novel anticancer drug that selectively inhibits the proliferation of cancer cells. It binds to the DNA and RNA in tumor cells to inhibit nucleotide synthesis and leads to cell death. This product has high purity and is modified for use.</p>

<p>3'-Amino-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine is a novel 3'-amino nucleoside</p>

<p>1-(a-D-Mannopyranosyl)-6-methoxypurine is a synthetic nucleoside that is an activator for the purine receptor. It has been shown to inhibit the growth of various tumor cells and to have antiviral properties. 1-(a-D-Mannopyranosyl)-6-methoxypurine is a novel nucleoside that was first synthesized in 1988, but has not been used in clinical trials or approved by the FDA. This product is made with high purity and high quality standards, and has a CAS number (13961-47-2).</p>

<p>Please enquire for more information about N4-Benzoyl-5’-O-DMT-morpholinocytidine-N’-CE phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2',3'-Anhydrothymidine is a nucleoside analogue that has been shown to inhibit HIV-1 transcriptase and polymerase by binding to the enzyme's active site. It also inhibits DNA synthesis in human cells and inhibits the growth of E. coli. 2',3'-Anhydrothymidine is a prodrug that can be taken up by cells, where it is converted into an epoxide, which then binds to the enzyme's active site. This prevents the enzyme from catalyzing reactions and terminating DNA synthesis at the correct point during transcription. 2',3'-Anhydrothymidine may also have immunodeficiency-related benefits due to its ability to bind more tightly to dsDNA than natural nucleotides, causing termination of RNA synthesis at the wrong point.</p>

<p>5'-O-DMT-2,3'-anhydrothymidine is a solvent that is used for labeling nucleic acids. It can be used in positron emission tomography (PET) imaging as a diagnostic tool for cancer and other diseases. 5'-O-DMT-2,3'-anhydrothymidine is also used to carry the radioactive isotope fluorodeoxyglucose (FDG) in positron emission tomography (PET). The FDG is labeled with the PET tracer and then injected into the patient's body. This allows for whole-body visualization of glucose metabolism and tumor cell uptake.</p>

<p>3’-Deoxy-3’C-methyladenosine is a reaction product of DNA and cancer cells. This product is generated by the glycosylase enzyme, which removes a methyl group from cytosine to produce 3’-deoxyadenosine. It has been shown that 3’-deoxy-3’C-methyladenosine accumulates in animal tissues after chronic treatment with an anticancer drug and can be detected using chromatographic methods. The presence of this compound in animals can be used as an indicator for carcinogenesis. 3’-Deoxy-3’C-methyladenosine has also been shown to inhibit the replication of mammalian cells.</p>

<p>A morpholino amidite</p>

<p>A morpholino amidite</p>

<p>a morpholino amidite</p>

<p>Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is a novel, modified nucleoside that is chemically synthesized from 2,3,4,6-tetraaminopyrimidine. It has antiviral activity and can be used to treat HIV infections. It is an active form of thymidine and inhibits the synthesis of viral DNA by blocking the activity of viral DNA polymerase in reverse transcription. This drug also exhibits anticancer activity by preventing cell proliferation and inducing apoptosis. Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is high purity with a CAS number of 63625-04-9.</p>

<p>Lauroyl CoA is a body-fat molecule that can be formed from acetyl-coenzyme A, which is an intermediate in the metabolism of fatty acids. It is used in analysis as a standard for enzyme activities and as a substrate for reactions involving enzymes with coenzyme A. Reaction mechanisms are determined using titration calorimetry and structural analyses are performed using analytical methods such as infrared spectroscopy and nuclear magnetic resonance spectroscopy. Lauroyl CoA is also used to study the effects of the protein toll-like receptor 4 on hepatic steatosis. The wild-type strain of Escherichia coli was used to measure the activity of bacterial synthetases containing lauroyl CoA.</p>

<p>N6-Benzoyl-2’-O-tert-butyldimethylsilyl-3’-O-DMT-adenosine is a novel nucleoside that is an activator of ribonucleotide reductase and an inhibitor of deoxyribonucleotide reductase. It has been shown to have antiviral and anticancer activities, as well as the ability to inhibit DNA synthesis. The synthetic route to this compound begins with the synthesis of N6-(benzoyl)-2'-O-(tert-butyldimethylsilyl)-3'-O-(dimethoxytrityl)adenosine, which is then converted to the final product by removal of the silyl protecting group and oxidation.</p>

<p>6-Methylthiopurine ribonucleotide is an inhibitor that belongs to the group of analogs of betamethasone. It has been shown to have anti-cancer properties and can induce apoptosis in cancer cells. This compound has also been studied for its potential use in treating urinary tract infections, as it has been shown to inhibit the growth of bacteria such as chlorhexidine-resistant strains. Additionally, 6-Methylthiopurine ribonucleotide has been found to be a potent inhibitor of human kinase and may have therapeutic potential for a variety of diseases. This compound has also been investigated as an inhibitor of tolvaptan, which is used to treat conditions such as hyponatremia. Overall, 6-Methylthiopurine ribonucleotide shows promising potential for the treatment of various diseases and conditions.</p>

<p>2',3',5'-Tris-O-[tert-butyldimethylsilyl]-2-chloroadenosine is a phosphoramidite that can be used in the synthesis of ribonucleosides, deoxyribonucleosides, and nucleoside analogues. It is a novel compound that has antiviral and anticancer properties. This product is synthesized from 2,3,5-trichloropyrimidine by reaction with tert-butyldimethylsilyl chloride in the presence of triethylamine. The product is purified by vacuum distillation and characterized using proton nuclear magnetic resonance (NMR) spectroscopy.</p>

<p>5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt is a modified nucleoside with anticancer activity. It is a diphosphate that can be used for the synthesis of DNA and RNA. This product is synthesized by the reaction of 5'-O-dimethoxytritylthymidine (5'-DMTT), 2'-O-(2-methoxyethyl)hydroxylamine hydrochloride, and succinic anhydride in the presence of triethylamine. The product is purified by column chromatography, followed by recrystallization from hot acetonitrile. CAS No.: 102972-73-0</p>

<p>5-Aminomethyluridine is a chemical compound that is involved in protein synthesis. It has been shown to inhibit the production of methylated uridines and cytosine, as well as the formation of 5-methylcytosine by methyltransferase. It also inhibits protein synthesis in human cells. 5-Aminomethyluridine may be able to block the progression of infectious diseases by inhibiting protein synthesis in the host cell. The compounds have been shown to inhibit the catalytic subunit of ribonucleotide reductase and RNA polymerase II, which are vital for cellular replication.</p>

<p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution is a high purity synthetic compound that is used as an activator for the synthesis of DNA, RNA, and phosphoramidites. The product is in the form of a white to off-white solid and has high quality with purity of &gt;99%. 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution can be used in antiviral, anticancer, and antideoxyribonucleoside therapy. It inhibits viral replication by inhibiting reverse transcriptase activity in HIV and other retroviruses. It also inhibits tumor growth by interfering with DNA synthesis.</p>

<p>7-Deaza-2'-deoxy-5'-O-DMT-adenosine is a nucleoside that has been synthesized by reacting 7-deaza-2'-deoxyadenosine with 5,6,7,8-tetrahydro-1H-[1]pyrazolo[3,4]pyrimidin-4(3H)-one. It is a novel anticancer agent that has been shown to inhibit the proliferation of various tumor cells in vitro. The cytotoxic effects of 7-deaza-2'-deoxy-5'-O-DMT adenosine are due to its ability to activate DNA synthesis while inhibiting DNA repair. It also inhibits ribonucleotide reductase and protein synthesis.</p>