
Nucleosides
Found 3569 products of "Nucleosides"
3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine
CAS:3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine is a novel nucleoside phosphoramidite. The 3'-azido group can be used to protect the 5' hydroxyl group during phosphitylation, which is essential for the synthesis of modified nucleosides. The 2',3'-dideoxy configuration ensures that the sugar moiety is not cleaved from the base during polymerization, and that no undesired side reactions occur during purification. This product has been shown to have antiviral and anticancer activity in vitro.
Formula:C20H32N8O4SiPurity:Min. 95%Molecular weight:476.61 g/molRef: 3D-NA145611
Discontinued product5'-O-DMT-N2-phenylacetylguanosine
CAS:5'-O-DMT-N2-phenylacetylguanosine is a novel synthetic nucleoside phosphoramidite which can be used for the synthesis of modified oligonucleotides. It has been shown to be an activator, anticancer, and antiviral agent in vitro. 5'-O-DMT-N2-phenylacetylguanosine is also a monophosphate, which can inhibit viral replication by interacting with the ribose sugar moiety of the nucleic acid strand. The antiviral activity has been demonstrated on human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus.
Formula:C39H37N5O8Purity:Min. 95%Molecular weight:703.76 g/molNicotinic acid-13C6 riboside
CAS:Please enquire for more information about Nicotinic acid-13C6 riboside including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C6C5H13NO6Purity:Min. 95%Molecular weight:260.17 g/mol3'-deoxy-3',4'-didehydrouridine
CAS:3'-deoxy-3',4'-didehydrouridine is a synthetic nucleoside that inhibits viral replication. It is an antiviral agent that has been shown to be effective against DNA and RNA viruses. The synthesis of this compound has been described in the literature. This product is available in high purity and high quality, and CAS No. 2166167-51-5. 3'-deoxy-3',4'-didehydrouridine has also been shown to have anticancer activity, and is a novel synthetic nucleoside.
Formula:C9H10N2O5Purity:Min. 95%Molecular weight:226.19 g/mol8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.Formula:C10H17N6O13P3·xNaPurity:Min. 95%Molecular weight:522.2 g/molRef: 3D-NA12011
Discontinued product2',5'-Dideoxyinosine
CAS:2',5'-Dideoxyinosine is a nucleoside that can be used as an antiviral or anticancer agent. It is synthesized from the natural nucleoside inosine by phosphorylation of the hydroxyl group on position 5 of the sugar ring and replacement of the hydroxyl group on position 2 with a deoxyribose. The resulting product has a higher potency than the natural form, and is more stable to enzymatic hydrolysis. 2',5'-Dideoxyinosine has been shown to inhibit DNA polymerase in vitro, and also inhibits RNA synthesis, leading to cell death. In addition, it has been shown to be active against leukemia cells as well as breast cancer cells in vivo.
Formula:C10H12N4O3Purity:Min. 95%Molecular weight:236.23 g/molRef: 3D-ND08407
Discontinued productIsowyosine
CAS:Isowyosine is a protein that catalyzes the synthesis of purines, which are essential for DNA synthesis and repair. Isowyosine is found in mammalian cells, where it has been observed to play a role in the translation of messenger RNA (mRNA). Isowyosine also plays a role in the synthesis of viral proteins and viral replication. It has been shown to be active against various viruses, including herpes simplex virus and influenza virus. Isowyosine may also have anti-cancer properties due to its ability to inhibit tumor growth.
Formula:C14H17N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:335.32 g/molRef: 3D-NI159495
Discontinued productCytidine 5'-monophosphate sodium salt
CAS:Cytidine 5'-monophosphate sodium salt is a nucleotide that is found in RNA and DNA. Cytidine 5'-monophosphate sodium salt is an intermediate in the biosynthesis of uridine, choline, and saccharose. It also plays an important role in the immune system as it can be a precursor for immunoglobulins. The reaction rate of cytidine 5'-monophosphate sodium salt with lipase has been shown to be constant at pH 7.5-8.0 and 37°C. This product has been shown to have emulsifying properties by forming micelles with water-immiscible solvents such as hexane or heptane, which may be due to its ability to form hydrogen bonds with other molecules such as saccharose or guanosine. Cytidine 5'-monophosphate sodium salt can also be used as a chromatographic material for separating saccharose from other sugars
Formula:C9H14N3O8P·xNaPurity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:323.2 g/molN4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine
N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine is a nucleoside that is used as an antiviral and anticancer agent. It is a modified deoxyribonucleoside that has antiviral activity against HSV-1, HSV-2, and HIV. N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine also has anticancer effects against leukemia cells in mice. This drug is synthesized from 2′,3′,5′triacetyladenosine by the reaction of 4-(1H)-benzoyloxymethyl)phenylacetic acid with triethylamine and levulinic acid chloride.
Formula:C21H23N3O7Purity:Min. 95%Molecular weight:429.43 g/mol5-Isopropyl-2'-deoxyuridine
CAS:5-Isopropyl-2'-deoxyuridine is a nucleoside analog that is used in the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of Crohn's disease, ulcerative colitis, and indeterminate colitis. 5-Isopropyl-2'-deoxyuridine inhibits bacterial growth by inhibiting RNA synthesis, which leads to cell death. This drug also inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes that are released from cells infected with bacteria. 5-Isopropyl-2'-deoxyuridine is converted into an active form by hydrolysis or oxidation followed by phosphorylation. This drug binds to the 5' end of bacterial DNA and prevents the formation of hydrogen bonds between adjacent bases, causing strand breakage.
Formula:C12H18N2O5Purity:Min. 95%Molecular weight:270.28 g/molRef: 3D-NI16765
Discontinued product2'-Deoxyadenosine phosphoramidite dimer
2'-Deoxyadenosine phosphoramidite dimer is a novel nucleoside analog that has been shown to be an effective anticancer agent in vitro. It has also been shown to inhibit viral replication and induce apoptosis in infected cells. This product is used as a DNA monophosphate, diphosphate, and triphosphate activator to increase the efficiency of DNA synthesis. It is also used as a precursor for the synthesis of other nucleosides such as 2'-deoxycytidine phosphoramidite dimer.
Purity:Min. 95%Ref: 3D-PD145901
Discontinued product5’-Azido-2’,5’-dideoxyuridine
CAS:5’-Azido-2’,5’-dideoxyuridine (5ADU) is a pyrimidine nucleoside that has been used to treat cancer. It is converted to 5-azidouracil which inhibits the synthesis of thymidylate, an essential component of DNA. 5ADU is also active against herpes virus and can be used as an antiviral agent. This drug has been shown to protect against radiation damage by inhibiting the formation of free radicals. The protonation of 5ADU leads to a stereochemical rearrangement that prevents the formation of free radicals. 5ADU does not inhibit bacterial enzymes, but it does have some effect on viruses, such as herpes virus, because they contain DNA or RNA similar to human cells.
Formula:C9H11N5O4Purity:Min. 95%Molecular weight:253.21 g/molRef: 3D-NA163034
Discontinued productrac-Lamivudine acid
CAS:Lamivudine is an antiviral drug that is used as a nucleoside analogue. It is a prodrug that is converted to its active form, which inhibits the viral enzyme reverse transcriptase by interfering with the synthesis of viral DNA. Racemic lamivudine acid (LAM) crystallizes in the form of chains with hydrogen bonds oriented in an impurity plane. The LAM molecule has two substituents, one carboxylate and one oxathiolane group.
Formula:C8H9N3O4SPurity:Min. 95%Molecular weight:243.24 g/molRef: 3D-NL27534
Discontinued product5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuanosyl)-1H-benzimidazole
CAS:5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-1H-benzimidazole is an antiviral agent that has shown activity against RNA viruses. It is a modified nucleoside monophosphate that inhibits the synthesis of viral ribonucleic acid (RNA) by binding to the enzyme RNA polymerase. 5,6-Dichloropurine is also a novel anticancer drug with antiangiogenic and antitumor properties. The compound was found to be effective in inhibiting the growth of human cancer cells in vitro. 5,6-Dichloropurine has been shown to inhibit protein synthesis through inhibition of diphosphate activation of ribonucleotide reductase and DNA polymerase. This product is synthesized using high purity and high quality reagents with excellent yield. It can be used as anFormula:C18H18Cl2N2O7Purity:Min. 95%Molecular weight:445.25 g/molRef: 3D-ND16534
Discontinued product2'-Deoxycytidine-5'-carboxylic acid
CAS:2'-Deoxycytidine-5'-carboxylic acid (2'-DC) is a modified nucleoside that has been used as an anticancer, antiviral, and synthetic agent. 2'-DC inhibits the synthesis of DNA by binding to the enzyme DNA polymerase. It also inhibits viral replication by inhibiting the activity of reverse transcriptase and can be used as a potential anti-HIV drug. In addition, 2'-DC has been shown to have cytotoxic effects against cancer cells in vitro. This compound is synthesized from cytidine 5-monophosphate and phosphoramidite reagents in high purity and quantity. The CAS number for this compound is 4603-72-9.
Formula:C9H11N3O5Purity:Min. 95%Molecular weight:241.2 g/mol2’-Deoxy-2-methyladenosine
CAS:2’-Deoxy-2-methyladenosine is a nucleoside that is chemically synthesized by the phosphorylation of 2,6-diaminopurine. It has been shown to be an effective activator of RNA polymerase and it also has anticancer properties. 2’-Deoxy-2-methyladenosine can be used as a substitute for thymidine in DNA synthesis. This nucleoside has also been shown to inhibit bacterial growth in culture by inhibiting DNA synthesis and protein synthesis. It is a modified nucleoside that can be used for the synthesis of DNA, RNA, or ribonucleic acids. The CAS number for this compound is 110952-90-4.
Purity:Min. 95%Ref: 3D-ND163169
Discontinued product8-Aza-2'-deoxyadenosine
8-Aza-2'-deoxyadenosine is an anion that is cytotoxic to cells and can be activated to form a phosphate ester. It has been shown to have a higher cytotoxicity than adenosine in cell cultures, but is less effective in animal studies. 8-Aza-2'-deoxyadenosine has been shown to have a significant toxicity in rats and mice when administered at doses greater than 500 mg/kg body weight. The activation of 8-aza-2'-deoxyadenosine into the phosphate ester can be stereoselective. This activation has also been shown to cause enhancement of tumor growth inhibition.
Purity:Min. 95%Ref: 3D-NA141794
Discontinued product5'-O-DMT-2'-O-propylphthalimidouridine
5'-O-DMT-2'-O-propylphthalimidouridine is a synthetic nucleoside that has antiviral and anticancer properties. It is used as a precursor for the synthesis of other nucleosides, including uridine and cytidine. 5'-O-DMT-2'-O-propylphthalimidouridine can be modified with phosphoramidites to create novel modified nucleosides. The chemical name is 1-(5'-O-dimethoxytrityl)-2-[(2' -propyl)thio]uracil. This drug has CAS number 61381-14-4 and molecular weight of 271.11 g/mol.
Formula:C41H39N3O10Purity:Min. 95%Molecular weight:733.78 g/molRef: 3D-ND08421
Discontinued product5-Methyl-2',3'-stannyluridine
5-Methyl-2',3'-stannyluridine is a nucleoside analog that is a potent inhibitor of viral replication and can be used for the treatment of HIV. It has been shown to inhibit the activity of RNA polymerase, thereby preventing transcription and replication. 5-Methyl-2',3'-stannyluridine also inhibits DNA synthesis by inhibiting the activity of DNA polymerase. This drug also acts as an antitumor agent and has been shown to inhibit tumor growth in animal models. The high purity of this drug makes it suitable for use in pharmaceutical applications.
5-Methyl-2',3'-stannyluridine is a modified nucleoside that has been modified with a stannyl group at the 2' position on the sugar moiety and an allyl group at the 3' position on the sugar moiety. The phosphoramidites are synthesized from 5-methyl-2',3'-stannylPurity:Min. 95%6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one
CAS:6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is a novel nucleoside analog that has been modified to contain an antiviral agent. It is phosphorylated at the 2' position to form a monophosphate. This compound is a potent inhibitor of HIV reverse transcriptase and human DNA polymerases α and β. The structure of this compound contains a furano ring fused with the pyrimidine moiety, which is substituted with methyl groups on C6 and C3 positions. The CAS number for 6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is 383897−60−7.Formula:C12H14N2O5Purity:Min. 95%Molecular weight:266.25 g/molRef: 3D-IQA89760
Discontinued product
