Nucleosides

<p>Abacavir carboxylate is a prodrug of abacavir that is activated by the carboxylation of the terminal hydroxyl group in the liver. It has been shown to be quantified using a liquid chromatography-mass spectrometry (LC-MS) method. Abacavir carboxylate has an additional benefit of being less sensitive to degradation by nitrate, which can interfere with the analysis of acyclovir. The deuterium label on abacavir carboxylate ensures that it is not confused with acyclovir and facilitates identification in wastewater samples.</p>

<p>2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is an antiviral agent of the deoxyribonucleoside family. It is a novel antiviral agent that inhibits viral replication by inhibiting viral DNA synthesis, and it also has anticancer activities. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is modified from guanosine monophosphate (GMP), which is a nucleotide precursor in DNA synthesis, and can be used as an activator for phosphoramidites in the synthesis of DNA.</p>

<p>N6-Benzoyl-7'-OH-morpholino adenosine is a modified nucleoside with antiviral activity. It is being developed as an activator of ribonucleotide reductase and a potential anticancer agent. N6-Benzoyl-7'-OH-morpholino adenosine is synthesized by reacting benzoyl chloride with 7'-O-dimethoxytritylmorpholine. This reaction results in the formation of the desired product, which has been shown to be an activator of ribonucleotide reductase. The synthesis of this compound can be performed on a large scale, making it an attractive candidate for chemotherapeutic use.</p>

<p>2'-O-tert-Butyldimethylsilyluridine is a nucleoside that is used in DNA synthesis, antiviral research, and anticancer therapy. It is synthesized from 2'-deoxyuridine monophosphate (2'-dUMP) with the aid of a phosphoramidite coupling agent. It has shown to be an effective activator in the synthesis of oligonucleotides, which are short chains of nucleotide units that can be used for various purposes including the treatment of cancer cells. These chains are synthesized by linking together individual nucleosides with phosphate molecules at each end. The bonds between these phosphate groups and the sugar-phosphate backbone of the nucleotide units are called phosphodiester bonds. This synthetic process can be used to produce DNA or RNA strands as well as modified versions of these strands such as those that have been synthesized with other chemical groups on their sugar-phosphate backbones.</p>

<p>5'-O-DMT-2'-O-propynyluridine 3'-CE phosphoramidite is a novel nucleoside analogue that can be used to synthesize DNA and RNA. This compound has antiviral and anticancer properties, which may be due to its ability to inhibit the synthesis of RNA. This product is also high quality, high purity, and low cost. 5'-O-DMT-2'-O-propynyluridine 3'-CE phosphoramidite is an excellent chemical intermediate for the synthesis of nucleosides with modified sugar moieties. It can be used in pharmaceuticals and other chemical industries.</p>

<p>2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine is a novel nucleoside that was synthesized as a potential antiviral agent. It is an analog of adenosine and has been shown to inhibit the replication of HIV in vitro. This nucleoside is synthesized using a modified phosphoramidite approach and can be used in the synthesis of DNA or RNA. 2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine has also been shown to have anticancer activity.</p>

<p>2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite is a nucleotide analog that is used for the treatment of cancer. It inhibits sugar transport, which leads to tumor cell lysis. 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite binds to glut1 and toll-like receptor 4 in the cell membrane, inhibiting the activation of these cells. This drug has been shown to have an antibody response in myeloma cells and basic fibroblast cell lines.</p>

<p>2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-O-succinate triethylammonium salt is a novel phosphoramidite that can be used as an activator for DNA synthesis. It is activated by the addition of an appropriate nucleophile and has been shown to be effective in antiviral and anticancer activities. This compound is synthesized through a modified diphosphate method and it is available in high purity with a CAS number.</p>

<p>2',3'-Dideoxy-3'-fluorocytidine is a synthetic nucleoside analog that inhibits DNA synthesis by blocking the incorporation of deoxycytidine into DNA. It is used to treat lymphocytic leukemia, hepatitis, and virus infections. 2',3'-Dideoxy-3'-fluorocytidine has been shown to inhibit cell growth in solid tumours. The drug has also been shown to inhibit the production of immunodeficiency viruses such as human immunodeficiency virus type 1 (HIV-1) and human T-lymphotropic virus type I (HTLV-I), which causes acquired immune deficiency syndrome (AIDS). 2',3'-Dideoxy-3'-fluorocytidine inhibits viral replication by inhibiting the activity of the enzyme deaminase, which converts dATP to dTTP. This prevents DNA replication and transcription.</p>

<p>Valopicitabine is a prodrug that is converted to its active form, 3'-deoxy-3'-methylvalopicitabine, in the body. Valopicitabine inhibits viral replication by a mechanism that is not yet fully understood. It has been shown to inhibit NS3 protease and induce an interferon response. Valopicitabine has also been shown to inhibit Toll-like receptor 4 (TLR4) activity and elicit an antiviral response. Valopicitabine has low bioavailability, which may be due to its high lipophilicity.</p>

<p>3'-O-Methyl-5'-guanylic acid is a novel antiviral, synthetic deoxyribonucleoside which is activated by phosphoramidites to produce 3'-O-methyl-5'-guanylic acid phosphoramidite. It has high purity and quality and can be used as a nucleoside activator for DNA synthesis. 3'-O-Methyl-5'-guanylic acid has been shown to be an anticancer agent that inhibits the growth of cancer cells in vitro by inhibiting DNA synthesis and cell division. This drug also has a potential use as an antiviral agent.</p>

<p>3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is Novel and Antiviral. 3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is Synthetic and Deoxyribonucleosides. 3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is High quality and Ribonuclesides. 3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution has CAS No. 51445-81-9, Activator, Phosphoramidites, Modified and Anticancer.</p>

<p>Inosine 2',3'-cyclic monophosphate sodium salt (ICMP) is a phosphodiesterase inhibitor that inhibits the activity of protein kinases and phosphatases. ICMP is used in biochemical studies to inhibit tryptophan metabolism and protein synthesis. It also has been shown to be useful in the study of sequences, such as those found in DNA and RNA. ICMP has been shown to increase the mRNA levels of a number of proteins at lower concentrations than other inhibitors, making it a valuable tool for studying protein synthesis. The enzyme-inhibiting properties of ICMP have been observed in calf thymus DNA and bacterial DNA gyrase, dna topoisomerase, and rna synthesis. ICMP also inhibits caenorhabditis elegans phosphatases and can be used in genetic engineering experiments involving Xenopus oocytes.</p>

<p>3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a novel antiviral drug with anticancer activity. It is an inhibitor of the enzyme ribonucleotide reductase and has been shown to inhibit the production of deoxyribonucleosides in tumor cells. It also inhibits DNA synthesis by inhibiting DNA polymerase. 3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a high purity product that is available in both monophosphate and diphosphate forms.</p>

<p>7,8-Dihydro-8-thioxo-adenosine is a synthetic nucleoside that activates the synthesis of DNA and RNA by acting as a ribonucleotide. It also has antiviral and anticancer activities. 7,8-Dihydro-8-thioxo-adenosine is an antiviral agent against herpesviruses and retroviruses. The antitumor activity of this compound is due to its ability to inhibit the proliferation of tumor cells by inhibiting DNA synthesis. 7,8-Dihydro-8-thioxo-adenosine can be used in the treatment of leukemia and other cancers that are sensitive to cytotoxic drugs. This drug has been shown to have low toxicity in rats.</p>

<p>7-Benzyl-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine is an antiviral agent that is a modified nucleoside. It has shown to be a novel activator of the immune system. 7BICP has been shown to have high antiviral activity against herpes simplex virus type 1 (HSV1) and type 2 (HSV2) in cell cultures. It also inhibits the replication of HIV and influenza A virus in cell cultures. This drug is synthesized from deoxyribonucleosides, phosphoramidites, or nucleosides. 7BICP is a monophosphate and diphosphate, which are used as substrates for DNA synthesis by DNA polymerase. The CAS number for 7BICP is 1244855-59-1.</p>

<p>2-Methyl-cytidine-(Bz)-succinyl-CPG; 500 Å (RNA) is a nucleoside analog that is modified with a 2'-methyl group. It is synthesized by the phosphoramidite method, which is performed in a high purity and high quality environment. This product can be used as an activator for DNA synthesis and has been shown to have anti-cancer and antiviral properties.</p>

<p>3,5-Di-O-toluoyl 6-chloropurine-7-b-D-deoxyriboside is a modified monophosphate nucleotide with antiviral and anticancer activity. It has been shown to be a potent activator of the enzyme DNA polymerase in vitro. This drug is synthesized by reacting 3,5-di-O-toluoyl 6-chloropurine with boron trichloride at high temperature. The final product was purified by HPLC and characterized using mass spectrometry. The purity of this compound is &gt;99% as determined by HPLC analysis.</p>

<p>5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite is an antiviral agent that has been shown to inhibit the replication of HIV in cell culture and to prevent the synthesis of the virus. 5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite inhibits viral replication by acting as a competitive inhibitor of HIV reverse transcriptase and blocking viral DNA synthesis from viral RNA. It has also been shown to have anticancer properties, which may be due to its ability to suppress tumor growth through inhibition of protein synthesis.</p>

<p>2'-Azido-2'-deoxyguanosine is an analog of guanine that is used as a fluorescent probe in biochemical and chemical biology studies. It can be synthesized using the azide method, which involves coupling an azide functional group to an aromatic ring. 2'-Azido-2'-deoxyguanosine can also be modified by a number of modifications, including attachment of fluorescent molecules or biotin for labeling purposes. The chemical structure of this compound has been shown to have a conformation that is similar to that of natural guanosine and uridine. 2'-Azido-2'-deoxyguanosine can be detected by proton nuclear magnetic resonance spectroscopy at about 3 ppm, which corresponds to its chemical shift in the range of 200–300 Hz. This compound also has biochemical properties that are similar to those observed for natural guanine and uridine.</p>