Anthracyclines
Anthracyclines are a class of potent antitumoral antibiotics that are widely used in cancer chemotherapy. These compounds work by intercalating into DNA, thereby disrupting the function of topoisomerase II and preventing the replication of cancer cells. Anthracyclines are particularly effective against a broad range of cancers, including leukemias, lymphomas, and breast cancer. However, their use is often limited by their cardiotoxicity, making research into safer and more effective formulations a key area of focus. At CymitQuimica, we provide a selection of anthracyclines for your research in oncology, drug development, and cancer therapy.
Found 172 products of "Anthracyclines"
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Doxorubicin
CAS:<p>Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.</p>Formula:C27H29NO11Purity:99.31%Color and Shape:Red Crystalline Solid SolidMolecular weight:543.52Idarubicinol (Mixture of Diastereomers)
CAS:<p>Stability Hygroscopic<br>Applications Idarubicinol is the alcohol analog of Idrabucin (I167000), an orally active anthracycline; analog of Daunorubicin. Antineoplastic.<br>References Arcamone, F., et al.: Caner Treat. Rep., 60, 829 (1976), Zini, G., et al.: Cancer Chemother. Pharmacol., 16, 107 (1986), Gillies, H.C., et al.: Br.J. Clin. Pharmacol., 23, 303 (1987), Villani, F., et al.: Eur. J. Cancer Clin. Oncol., 25, 13 (1989),<br></p>Formula:C26H29NO9Color and Shape:NeatMolecular weight:499.519,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin Hydrochloride
Controlled Product<p>Applications 9,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin is an impurity of Doxorubicin (D558000), an antineoplastic agent.<br></p>Formula:C26H26ClNO10Purity:>85%Color and Shape:NeatMolecular weight:547.94Doxorubicin impurity
CAS:<p>Doxorubicin is an organic compound that belongs to the class of polycyclic aromatic hydrocarbons. It is used as a cancer therapy, primarily in the treatment of breast cancer. The chemical sensing of impurities in doxorubicin can be done using phase transfer methods. The quantification of these impurities can be done using high-performance liquid chromatography (HPLC) or gas chromatography (GC).</p>Formula:C26H27NO11Purity:Min. 90 Area-%Color and Shape:Red PowderMolecular weight:529.49 g/mol14-Bromo, 13-Deoxo, 13,13-Dimethoxy Daunorubicin Hydrobromide (>85%)
CAS:Controlled Product<p>Applications (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione, is the metabolite of Doxorubicin (D558000), which is a neoplasm inhibitor,and an antineoplastic.<br>References Smith, T.H., et al.: J. Med. Chem., 22, 40 (1979); Di Marco, A., et al.: Cancer Chemother. Rep., (part 1), 53, 33 (1969), Mihich, E. and Ehrke, M.J.: Transplant. Proc., 16, 499 (1984),<br></p>Formula:C29H34BrNO11·BrHPurity:>85%Color and Shape:NeatMolecular weight:733.40Karminomycin Hydrochloride
CAS:<p>Applications Karminomycin Hydrochloride is an antibiotic that potently kills human tumor cells and their multidrug resistant variants. Highly active quinone-containing anticancer drugs. A new anthracycline antineoplastic antibiotic.<br>References Tevyashova, A. N., et al.: J. Antibiot., 57, 143 (2004); Bachur, N. R., et al.: Cancer Res., 38, 1745 (1978); Brazhnikova, M. G., et al.: J. Antibiot., 27, 254 (1974)<br></p>Formula:C26H27NO10·HClColor and Shape:NeatMolecular weight:549.9547,8,9,10-Dehydro Doxorubicinone (~70%)
CAS:Controlled ProductFormula:C21H14O8Purity:~70%Color and Shape:NeatMolecular weight:394.33
