G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
Found 5800 products of "G-protein Coupled Receptors and 7-TM Receptors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
20-SOLA
<p>20-SOLA is the first water-soluble 20-HETE antagonist with oral bioavailability. It significantly improves blood pressure changes and kidney damage associated with the streptozotocin (STZ) diabetic mouse model. Additionally, 20-SOLA acts as a GPR75 receptor blocker. This compound is useful in research related to cardiovascular pathology.</p>Formula:C33H62O9Molecular weight:602.43938Antibacterial agent 189
Antibacterialagent 189 (compound 3a) is a potent antibacterial agent with high binding affinity to the target proteins OMPA/exo-1,3-β-glucanase. It demonstrates effective antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Candida albicans, and Aspergillus flavus. Additionally, Antibacterialagent 189 exhibits strong binding affinity to the target proteins SMO and SUFU/GLI-1.Formula:C37H28N4OMolecular weight:544.22631NI-0701
<p>NI-0701 is a humanized antibody targeting CCL5/RANTES.</p>Purity:95.4% (SDS-PAGE); 99.4% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5kDaRF9 acetate
RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.Formula:C28H42N6O5Purity:99.77%Color and Shape:SolidMolecular weight:542.67Gulgafafusp alfa
CAS:Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1].Color and Shape:LiquidBombinakinin M
CAS:Potent, selective bradykinin receptor agonist 50x stronger than bradykinin, contracts guinea pig ileum muscle at EC50 4.0 nM.Formula:C100H159N31O24Purity:98%Color and Shape:SolidMolecular weight:2179.55NI-203
NI-203 is a monoclonal antibody inhibitor that targets amylin and shows potential for research in type 2 diabetes.Color and Shape:Odour LiquidMisoprostol acid
CAS:<p>Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers.</p>Formula:C21H36O5Purity:98%Color and Shape:SolidMolecular weight:368.51CYN 154806
CAS:CYN 154806: potent sst2 antagonist; pIC50: 8.58 (sst2), 5.41 (sst1), 6.07 (sst3), 5.76 (sst4), 6.48 (sst5).Formula:C56H68N12O14S2Purity:98%Color and Shape:SolidMolecular weight:1197.34Lys-Bradykinin
CAS:Endogenous bradykinin receptor agonistFormula:C56H85N17O12Purity:98%Color and Shape:SolidMolecular weight:1188.38O-2172
CAS:<p>O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).</p>Formula:C14H16Cl2O2Color and Shape:SolidMolecular weight:287.18Cianopramine hydrochloride
CAS:Cianopramine hydrochloride is a bio-active chemical.Formula:C20H24ClN3Color and Shape:SolidMolecular weight:341.885-HT2C agonist-4
CAS:<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Formula:C24H25N5OColor and Shape:SolidMolecular weight:399.49Mabuterol free base
CAS:Mabuterol: selective β2 agonist, inhibits isoprenaline, affects rat uterus and rabbit jejunum, alters intestinal propulsion.Formula:C13H18ClF3N2OPurity:98%Color and Shape:SolidMolecular weight:310.74Tetrahydro-β-carboline
CAS:<p>Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C11H12N2Purity:96.31%Color and Shape:Tan SolidMolecular weight:172.2264HTL22562
CAS:HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formula:C40H49N11O5Color and Shape:SolidMolecular weight:763.904Ici 216140
CAS:ICI 216140: GRP/bombesin receptor 2 blocker, potent at 2 nM. Reduces amylase at 2 mg/kg and lowers bombesin-induced blood pressure at 1 mM in rats.Formula:C45H65N13O8Color and Shape:SolidMolecular weight:916.08M1145
CAS:Potent GAL2 agonist with EC50 = 38 nM; Ki: 6.55 nM (GAL2), 497 nM (GAL3), 587 nM (GAL1); enhances galanin signaling.Formula:C128H205N37O32Purity:98%Color and Shape:SolidMolecular weight:2774.26Pancreatic polypeptide TFA
<p>Pancreatic polypeptide TFA acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.</p>Color and Shape:Odour SolidBromchlorbuterol hydrochloride
CAS:Bromchlorbuterol HCl, a potent β-agonist, is used to study lung diseases like asthma.Formula:C12H19BrCl2N2OColor and Shape:SolidMolecular weight:358.1
