G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
Found 5800 products of "G-protein Coupled Receptors and 7-TM Receptors"
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Isoxsuprine Free Base
CAS:Isoxsuprine Free Base relaxes uterine/vascular muscles, dilates arteries, treats peripheral vascular disease, and premature labor.Formula:C18H23NO3Color and Shape:SolidMolecular weight:301.38L-745870 trihydrochloride
CAS:<p>L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.</p>Formula:C18H22Cl4N4Purity:97.52%Color and Shape:SolidMolecular weight:436.21Bindarit
CAS:<p>Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.</p>Formula:C19H20N2O3Purity:98.35% - 98.55%Color and Shape:SolidMolecular weight:324.37F-15599
CAS:<p>F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).</p>Formula:C19H21ClF2N4OPurity:98.72%Color and Shape:SolidMolecular weight:394.85Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColor and Shape:SolidMolecular weight:467.92idalopirdine
CAS:Idalopirdine (Lu AE58054), a selective 5-HT6 receptor antagonist( Ki : 0.83 nM),as a treatment for Alzheimer's disease.Formula:C20H19F5N2OPurity:99.73%Color and Shape:SolidMolecular weight:398.37Obestatin (rat) acetate
Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39).Formula:C114H174N34O31Purity:99.05%Color and Shape:SolidMolecular weight:2516.81Buclizine
CAS:Buclizine is an orally active antihistamine, antiallergic compound. buclizine is also a strong teratogen in rats and exhibits antitumour effects.Formula:C28H33ClN2Color and Shape:SolidMolecular weight:433.03Haloperidol lactate
CAS:Haloperidol lactate: a potent antipsychotic for acute/chronic schizophrenia and polyarousal syndrome research.Formula:C24H29ClFNO5Color and Shape:SolidMolecular weight:465.95T-1095
CAS:T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Formula:C26H28O11Purity:99.78%Color and Shape:SolidMolecular weight:516.49Bromodiphenhydramine hydrochloride
CAS:<p>Bromodiphenhydramine hydrochloride is a new antihistaminic in the control of cutaneous.</p>Formula:C17H21BrClNOPurity:97.29%Color and Shape:SolidMolecular weight:370.71Acrivastine
CAS:Acrivastine (Acrivastin) is a short-acting histamine 1 receptor antagonist.Formula:C22H24N2O2Purity:99.73% - >99.99%Color and Shape:SolidMolecular weight:348.44Chlorprothixene
CAS:Chlorprothixene (Truxal) is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.Formula:C18H18ClNSPurity:98.77% - 99.756%Color and Shape:Pale Yellow Crystals SolidMolecular weight:315.86GSK2018682
CAS:<p>GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively).</p>Formula:C22H21ClN4O4Purity:99.04%Color and Shape:SolidMolecular weight:440.88Ufenamate
CAS:Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for skin diseasesFormula:C18H18F3NO2Purity:99.89%Color and Shape:SolidMolecular weight:337.34BD 1008 Free Base
CAS:BD 1008 Free Base: Sigma-1 receptor antagonist, Kᵢ = 2 ± 1 nM, 4x more selective for sigma-1 than sigma-2.Formula:C15H22Cl2N2Color and Shape:SolidMolecular weight:301.25ACEPROMAZINE MALEATE
CAS:ACEPROMAZINE MALEATE is a dopamine receptor antagonistFormula:C23H26N2O5SPurity:98.87% - 99.51%Color and Shape:Off White Or Yellow Crystalline PowderMolecular weight:442.53EST64454 free base
CAS:EST64454: σ1R antagonist for pain, high solubility, permeable, BCS class I, metabolically stable.Formula:C18H22F2N4O2Color and Shape:SolidMolecular weight:364.39LY 78335
CAS:LY 78335 (1-(2,3-Dichlorophenyl)ethanamine hydrochloride) is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.Formula:C8H10Cl3NPurity:99.30% - 99.81%Color and Shape:SolidMolecular weight:226.53SR 57227 hydrochloride
CAS:<p>SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.</p>Formula:C10H14ClN3·HClPurity:99.89%Color and Shape:SolidMolecular weight:248.15Tozadenant
CAS:Tozadenant (SYN115) is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus,respectively)Formula:C19H26N4O4SPurity:98%Color and Shape:SolidMolecular weight:406.5[Lys8, Lys9]-Neurotensin (8-13) acetate
<p>[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2</p>Formula:C40H68N8O10Purity:99.31%Color and Shape:SolidMolecular weight:821.022-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
<p>2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.</p>Formula:C38H64F3N11O10Purity:>99.99%Color and Shape:SolidMolecular weight:891.98BAY 41-8543
CAS:<p>BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).</p>Formula:C21H21FN8OPurity:99.86%Color and Shape:SolidMolecular weight:420.44RS-127445 hydrochloride
CAS:<p>RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).</p>Formula:C17H17ClFN3Purity:99.48%Color and Shape:SolidMolecular weight:317.79Ipragliflozin
CAS:<p>Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.</p>Formula:C21H21FO5SPurity:99.38% - 99.70%Color and Shape:SolidMolecular weight:404.45BRL-15572 hydrochloride
CAS:<p>BRL-15572 hydrochloride: selective h5-HT1D antagonist with high affinity; useful for studying h5-HT1D responses.</p>Formula:C25H28Cl2N2OColor and Shape:SolidMolecular weight:443.41Clomipramine
CAS:<p>Clomipramine treats OCD, depression, chronic pain, and may lower suicide risk in seniors; works by hindering serotonin reuptake.</p>Formula:C19H23ClN2Purity:99.31% - 99.71%Color and Shape:SolidMolecular weight:314.85Tiapride
CAS:<p>Tiapride, an atypical neuroleptic, is a selective dopamine D2-receptor antagonist with varying IC50 values for D1-D4.</p>Formula:C15H24N2O4SColor and Shape:SolidMolecular weight:328.43Temanogrel
CAS:<p>Temanogrel (APD791) is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).</p>Formula:C24H28N4O4Purity:99.24%Color and Shape:SolidMolecular weight:436.5R715 TFA(185052-09-9 free base)
R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49).Formula:C59H82F3N13O14Purity:>99.99%Color and Shape:SolidMolecular weight:1254.36Clebopride
CAS:Clebopride is antidopaminergic. Clebopride also has an effect of antiemetic.Formula:C20H24ClN3O2Color and Shape:SolidMolecular weight:373.88PNU-282987
CAS:PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).Formula:C14H18Cl2N2OPurity:99% - >99.99%Color and Shape:SolidMolecular weight:301.21Almotriptan
CAS:Almotriptan (LAS 31416), a triptan and 5-HT1B/1D agonist, treats migraines by constricting cranial vessels and altering blood flow.Formula:C17H25N3O2SPurity:99.85%Color and Shape:Light Yellow Or White PowerMolecular weight:335.46Vilanterol trifenatate
CAS:Vilanterol trifenatate is a long-acting agonist of β2-adrenoceptor (β2-AR) with inherent 24-hour activity(β2-AR, β1-AR and β3-AR pEC50s of 10.37, 6.98 and 7.36, respectively)Formula:C44H49Cl2NO7Purity:99.51% - >99.99%Color and Shape:SolidMolecular weight:774.77Ansofaxine hydrochloride
CAS:<p>Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).</p>Formula:C24H32ClNO3Purity:99.57% - 99.77%Color and Shape:SolidMolecular weight:417.97Men 10376 TFA(135306-85-3,free)
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4Formula:C59H69F3N12O12Purity:99.22%Color and Shape:SolidMolecular weight:1195.25ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139GSK189254A
CAS:<p>GSK189254A (GSK189254) is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3).</p>Formula:C21H25N3O2Purity:98.71% - 99.858%Color and Shape:SolidMolecular weight:351.44SCH 58261
CAS:SCH 58261 is a potent and selective A2a adenosine receptor antagonist.The Ki =2.3 nM for rat A2a and 2 nM is for bovine A2a.Formula:C18H15N7OPurity:99.07% - 99.75%Color and Shape:SolidMolecular weight:345.36Lidamidine Hydrochloride
CAS:Lidamidine HCl: α2-adrenergic agonist; lowers gut secretion, slows transit, stops muscle contractions.Formula:C11H17ClN4OColor and Shape:SolidMolecular weight:256.73Neurotensin(8-13) 3TFA(60482-95-3(free base))
CAS:Neurotensin(8-13) 3TFA is Neurotensin (NT) fragment. Neurotensin(8-13) 3TFA results in a decrease in cell-surface NT1 receptors (NTR1) density.Formula:C40H65F3N12O10Purity:98.31%Color and Shape:SolidMolecular weight:931.03Nonapeptide-1 acetate salt (158563-45-2 free base)
<p>Nonapeptide-1 acetate salt (158563-45-2 free base) (Melanostatine-5 acetate salt) , a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH)</p>Formula:C63H91N15O11SPurity:98.26%Color and Shape:SolidMolecular weight:1266.58BD 1008 dihydrobromide
CAS:<p>BD 1008 dihydrobromide: selective σ1 receptor antagonist (Ki=2 nM), high σ1 and moderate σ2 affinity.</p>Formula:C15H24Br2Cl2N2Purity:97.81%Color and Shape:SolidMolecular weight:463.08SAX-187 hydrochloride
CAS:WAY-181187 is a potent, selective 5-HT6 agonist with high affinity (2.2-4.8 nM), and increases GABA in rat cortex at 3-30 mg/kg s.c.Formula:C15H14Cl2N4O2S2Color and Shape:SolidMolecular weight:417.33LUN42518 HCl 47142-51-8(free base)
<p>LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.</p>Formula:C17H20ClN3OPurity:99.96%Color and Shape:SolidMolecular weight:317.81Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Formula:C36H47ClN8O3Purity:98.93%Color and Shape:SolidMolecular weight:675.3Guanethidine monosulfate
CAS:Guanethidine monosulfate is an antihypertensive drug that reduces the release of catecholamines.Formula:C10H24N4O4SPurity:99.61% - 99.74%Color and Shape:SolidMolecular weight:296.39Raclopride
CAS:Raclopride is a selective antagonist of dopamine D2/D3 receptor.Formula:C15H20Cl2N2O3Purity:99.17%Color and Shape:SolidMolecular weight:347.24
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