Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 178 products for "Complement System".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formula:C68H100F3N23O19S2Color and Shape:SolidMolecular weight:1664.79Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Color and Shape:Odour SolidComplement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFormula:C22H20F2N6OPurity:97.77%Color and Shape:Yellow SolidMolecular weight:422.43Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Formula:C29H28BrN7O3Color and Shape:SolidMolecular weight:602.493AMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Formula:C83H117N23O18S2Purity:98%Color and Shape:SolidMolecular weight:1789.11Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formula:C128H190N24O33Color and Shape:SolidMolecular weight:2593.02C5a Anaphylatoxin (human)
CAS:C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFormula:C350H578N108O107S8Purity:98%Color and Shape:SolidMolecular weight:8267.51tLyP-1 peptide
CAS:tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Formula:C31H59N15O10SColor and Shape:SolidMolecular weight:833.96CK3 peptide
CAS:CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.Formula:C40H72N12O12S2Color and Shape:SolidMolecular weight:977.203BCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Formula:C14H11ClN2O2S2Purity:99.71%Color and Shape:SolidMolecular weight:338.83Vensobafusp alfa
CAS:Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Color and Shape:LiquidOlendalizumab
CAS:Olendalizumab is an anti-C5a mAb that inhibits neutrophil activation and cytokine storms by blocking the C5a/C5aR axis for sepsis and viral infection research.Color and Shape:LiquidPOT-4 TFA
POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.Formula:C74H103F3N22O20S2Color and Shape:SolidMolecular weight:1741.87BM213
CAS:BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Formula:C43H70N12O10Purity:98%Color and Shape:SoildMolecular weight:915.09Campneoside II
CAS:Campneoside II, a compound extracted from the wood of Paulownia tomentosa var. tomentosa, demonstrates remarkable anti-complement activity [1].Formula:C29H36O16Color and Shape:SolidMolecular weight:640.59PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formula:C71H123N19O21S2·xC2HF3O2Color and Shape:Solid3-Phenoxybenzaldehyde
CAS:3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.Formula:C13H10O2Purity:99.01%Color and Shape:Transparent LiquidMolecular weight:198.22ASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Color and Shape:Odour LiquidComplement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Color and Shape:Lyophilized PowderMolecular weight:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement Factor MASP3 Protein, Human, Recombinant (His)
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.Color and Shape:Lyophilized PowderMolecular weight:95-120 KDa (reducing condition)Ref: TM-TMPJ-00980
5µg104.00€10µg170.00€20µg263.00€50µg490.00€100µg712.00€200µg1,035.00€500µg1,710.00€1mg2,457.00€
