Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 156 products of "Complement System"
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C1QA Protein, Human, Recombinant (His & Myc)
<p>C1QA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.</p>Color and Shape:Lyophilized PowderMolecular weight:30.7 kDa (predicted)C5AR1 Protein-VLP, Human, Recombinant (His)
<p>Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.</p>Color and Shape:Lyophilized PowderMolecular weight:41.1 kDa (predicted)Properdin Protein, Mouse, Recombinant (His)
<p>A positive regulator of the alternate pathway of complement.</p>Color and Shape:Lyophilized PowderMolecular weight:51.9 kDa (predicted)C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
<p>Expression system: E. coli<br>Length: 306-351, Partial<br>Activity: Not Tested</p>Color and Shape:Lyophilized PowderMolecular weight:52.8 kDa (Predicted)Complement C8g Protein, Human, Recombinant (His)
<p>C8 is a constituent of the membrane attack complex.</p>Purity:95%Color and Shape:Lyophilized PowderMolecular weight:26.4 kDa (predicted)CR1 Protein, Human, Recombinant
<p>Expression system: E. coli<br>Length: 41-234, Partial<br>Activity: Not Tested</p>Color and Shape:Lyophilized PowderMolecular weight:21.6 kDa (Predicted)C1SB Protein, Mouse, Recombinant (His & Myc)
<p>C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.</p>Color and Shape:Lyophilized PowderMolecular weight:82.4 kDa (predicted)C1QA Protein, Mouse, Recombinant (His)
<p>C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.</p>Purity:90% - 92%Color and Shape:Lyophilized PowderMolecular weight:25.6 kDa (predicted)Complement C3 Protein, Bovine, Recombinant (His & SUMO)
<p>Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E.</p>Color and Shape:Lyophilized PowderMolecular weight:39.5 kDa (predicted)Complement factor D Protein, Rat, Recombinant (His)
<p>Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate</p>Color and Shape:Lyophilized PowderMolecular weight:27.8 kDa (predicted)Empasiprubart
CAS:<p>Empasiprubart (anti-C2 mAb) inhibits classical & lectin complement pathways upstream of C3, showing efficacy in autoimmune models.</p>Purity:95%Color and Shape:LiquidCrovalimab
CAS:<p>Crovalimab (SKY59; RO7112689) is an humanised monoclonal antibody that binds to complement C5 , paroxysmal nocturnal haemoglobinuria (PNH).</p>Purity:95%Color and Shape:LiquidGefurulimab
CAS:<p>Gefurulimab (ALXN-1720) is a bispecific antibody derived from humans, targeting complement C5 and albumin.</p>Color and Shape:LiquidRiliprubart
CAS:<p>Riliprubart (SAR445088) is a humanized monoclonal antibody that acts as an anti-C1s inhibitor in the proximal part of the classical complement system. It selectively targets activated C1s, inhibiting its enzymatic activity on substrates C4 and C2, thereby preventing the formation of the classical pathway C3 convertase, C4b2a [1].</p>Purity:95% - 95%Color and Shape:LiquidIsocyclosporin A
CAS:<p>Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.</p>Formula:C62H111N11O12Color and Shape:SolidMolecular weight:1202.61C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Formula:C36H40FN5O2Color and Shape:SolidMolecular weight:593.73BCX 1470
CAS:<p>BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.</p>Formula:C14H10N2O2S2Purity:98%Color and Shape:SolidMolecular weight:302.37NRP1 antagonist 2
CAS:<p>NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.</p>Formula:C20H17ClN6OS2Color and Shape:SolidMolecular weight:456.97FD-IN-1
CAS:FD-IN-1: Factor D inhibitor, IC50=12 nM; blocks FXIa, Tryptase β2 (IC50s: 7.7 μM, 6.5 μM); key in innate immunity.Formula:C23H23NO4Color and Shape:SolidMolecular weight:377.43EG00229
CAS:<p>EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.</p>Formula:C19H20F3N7O7S3Purity:98.23%Color and Shape:SolidMolecular weight:611.6
