Aminoacids and derivatives

<p>Cy 3 (Non-Sulfonated) is a CY3-derived dye. CY3 is an amine-reactive cyanine orange dye for fluorescent labelling of proteins and nucleic acids.</p>

<p>Nordalbergin, a coumarin isolated from the bark of Dalbergia sissoo, can significantly induce the differentiation of HL-60 cells.</p>

<p>Applications Antifibrinolytic agent. Used in the preparation of Tranexamic Acid (T714505).<br></p>

<p>Applications Glycine-d2, is the labeled analogue of Glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.<br>References Scott, D., et al.: J. Neurosci., 21, 3063 (2001); Laube, B., et al.: Neuropharmacology, 47, 994 (2004); Papadakis, M., et al.: J. Biol. Chem., 279, 14703 (2004), Chen, P., et al.: Mol. Pharmacol., 67, 1470 (2005), Wolosker, H., et al.: Mol. Neurobiol., 36, 152 (2007);<br></p>

<p>Applications N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>

<p>Applications O-Methyl-3,3',5,5'-tetraiodothyronamine is a derivative of p-Tyramine (T898500); an adrenergic.<br>References Brandacher, G., et al.: Curr. Drug Metab., 8, 289 (2007); Oresic, M., et al.: J. Exp. Med., 205, 2975 (2008)<br></p>

<p>Applications N-Carbobenzoxy-S-phenyl-L-cysteine methyl ester is used in the preparation of γ-amino β-ketoesters by cross-Claisen condensation of α-amino acid derivatives with alkyl acetates.<br>References Honda, Y., et al.: Tetrahedron, Lett., 44, 3163 (2003);<br></p>