Natural and semi-synthetic antibiotics
Natural and semisynthetic antibiotics are characterised by chemical structures with heterocyclic rings and active functional groups that inhibit the growth of microorganisms. Their structures allow them to interact with vital bacterial processes, making them useful treatments for bacterial infections. Semisynthetic antibiotics can be modified to enhance their spectrum of activity or resistance to degradation.
At CymitQuimica, we offer high-quality natural and semisynthetic antibiotics for research in microbiology and pharmaceutical development.
Found 6348 products of "Natural and semi-synthetic antibiotics"
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7-Chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid
CAS:Controlled Product<p>Applications 7-Chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is a 1-arylated derivative of 1,4-dihydro-4-oxoquinoline-3-carboxylic acid with antibacterial activity.<br>References Radl, S. et al.: Coll. Czech. Chem. Comm., 54, 2181 (1989):<br></p>Formula:C16H8ClF2NO3Color and Shape:NeatMolecular weight:335.69Ethyl (Z)-[2-amino-4-thiazolyl](methoxyimino)acetate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Ethyl (Z)-[2-amino-4-thiazolyl](methoxyimino)acetate is used in the preparation of ceftriaxone-d3 (C245002), which is a labelled antibacterial.<br>References Reiner, R., et al.: J. Antibiot., 33, 783 (1980)<br></p>Formula:C8H11N3O3SColor and Shape:NeatMolecular weight:229.26N-t-Butyl N-Deactyl Linezolid
CAS:Controlled Product<p>Applications N-t-Butyl N-Deactyl Linezolid is a derivative of Linezolid (L466500), a prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation.<br>References Brickner, S.J., et al.: J. Med. Chem., 39, 673 (1996), Ford, C.W., et al.: Antimicrob. Agents Chemother., 40, 1508 (1996), Rybak, M.J., et al.: Pharmacotherapy, 18, 456 (1998), Stevens, D.L., et al.: Clin. Infect. Dis., 34, 1481 (2002),<br></p>Formula:C18H26FN3O3Color and Shape:Off-WhiteMolecular weight:351.423-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine
CAS:Controlled Product<p>Applications 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.<br>References Reading, C. and Cole, M.: Antimicrob. Ag. Chemother., 11, 852 (1977), Ball, A.P., et al.: Lancet, 1, 620 (1980), Brogden, R.N., et al. Drugs, 22, 337 (1981); Haginaka, J. et al.: Chem. Pharm. Bull., 33, 218 (1985);<br></p>Formula:C9H14N2O2Color and Shape:NeatMolecular weight:182.223-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic Acid
CAS:Controlled Product<p>Impurity Flucloxacillin EP Impurity D<br>Applications 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic Acid (Flucloxacillin EP Impurity D) is an impurity of Flucloxacillin (F419200), a new semisynthetic penicillin with broad spectrum of antibacterial activity.<br>References Macsari, I., et al.: Bioorg. Med. Chem. Lett., 21, 3871 (2011); Cui, Y., et al.: Curr. Sci., 89, 531 (2005);<br></p>Formula:C11H7ClFNO3Color and Shape:NeatMolecular weight:255.632’-O-Acetylspiramycin I
CAS:Controlled ProductFormula:C45H76N2O15Color and Shape:NeatMolecular weight:885.091-Hydroxy-2,7-diamino Mitosene (Mixture cis/trans)
CAS:Controlled Product<p>Applications Mitomycin (M371900) impurity.<br>References Siegel, D., et al.: Biochemistry, 31, 7879 (1992), Kontou, M., et al.: Oncogene, 21, 2406 (2002),<br></p>Formula:C14H16N4O5Color and Shape:NeatMolecular weight:320.304-(2-Fluoro-4-nitrophenyl)morpholine
CAS:<p>Applications 4-(2-Fluoro-4-nitrophenyl)morpholine is a reactant in the synthesis of 5-substituted oxazolidinone derivatives with high antimicrobial activity.<br>References De Rosa, M., et. al.: Eur. J. Med. Chem., 69, 779 (2013)<br></p>Formula:C10H11FN2O3Color and Shape:NeatMolecular weight:226.20δ2-Cefadroxil
CAS:<p>Stability Light and Temperature Sensitive<br>Applications Δ2-Cefadroxil is a derivative of Cefadroxil (C235750), a semi-synthetic cephalosporin antibiotic. Antibacterial.<br>References Buck, R.E., et al.: Antimicrob. Agents Chemother., 11, 324 (1977)<br></p>Formula:C16H17N3O5SColor and Shape:Off White SolidMolecular weight:363.39cis-Terbinafine Hydrochloride
CAS:Controlled Product<p>Impurity Terbinafine EP Impurity B<br>Applications cis-Terbinafine Hydrochloride (Terbinafine EP Impurity B) is an impurity in the production of Terbinafine hydrochloride.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Petranyi, G., et al.: Science, 224, 1239 (1984), Stutz, A., et al.: J. Med. Chem., 27, 1539 (1984),<br></p>Formula:C21H25N·ClHColor and Shape:WhiteMolecular weight:327.892-(5-Mercaptotetrazole-1-yl)ethanol
CAS:Controlled Product<p>Applications 2-(5-Mercaptotetrazole-1-yl)ethanolis a mercaptotetrazole derivative used as an intermediate in the preparation of beta-lactam antibiotic Flomoxef (F401850) as well one of its metabolite. 2-(5-Mercaptotetrazole-1-yl)ethanol also shows vitamin K-dependent glutamylcarboxylase inhibitory activity.<br>References Oka, T. et al.: Jap. J. Pharmacol., 46, 165 (1988); Konaka, R. et al.: Chemotherapy, 35, 137 (1987);<br></p>Formula:C3H6N4OSColor and Shape:NeatMolecular weight:146.17δ2-Cefotetan
CAS:Controlled Product<p>Applications The Δ2-isomer of Cefotean (C242970). It is useful as intermediate in the preparation of cephalesorin compounds.<br>References Sugioka, T., et al.: Chem. Pharm. Bull., 38, 1998 (1990),<br></p>Formula:C17H17N7O8S4Color and Shape:NeatMolecular weight:575.62(R)-5-(Chloromethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one
CAS:Controlled ProductFormula:C14H16ClFN2O3Color and Shape:NeatMolecular weight:314.74Nitroso-N-De methyl Erythromycin-D3
Controlled ProductFormula:C36D3H61N2O14Color and Shape:NeatMolecular weight:751.9172’-Tosyloxy-dihydropleuromutilin
CAS:Controlled Product<p>Applications Intermediate in the preparation of Azamulin<br></p>Formula:C29H42O7SColor and Shape:NeatMolecular weight:534.70Lovastatin-d9 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Lovastatin-d9, is the labeled analogue of Lovastatin (L472225), an antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase.<br>References Bilheimer, D.W., et al.: Proc. Nat. Acad. Sci. USA, 80, 4124 (1983),<br></p>Formula:C24H27D9O5Color and Shape:NeatMolecular weight:413.6Thienamycin (>80%)
CAS:Controlled Product<p>Stability Hygroscopic, Temperature Sensitive, Very Unstable<br>Applications Thienamycin is one of the most potent naturally produced antibiotics known thus far. It has excellent activity against both Gram-positive and Gram-negative bacteria and is resistant to bacterial β-lactamase enzymes.<br>References Kahan, J., et al.: J. Antibiot., 32, 1 (1979); Bradley, J., et al.: Int. J. Antimicrob. Agents, 11, 93 (1999); Spratt, B., et al.: Antimcrob. Agents Chemother., 12, 406 (1977);<br></p>Formula:C11H16N2O4SPurity:>80%Color and Shape:NeatMolecular weight:272.3224,32-Bis-O-(tert-butyldimethylsilyl)-FK-506
CAS:Controlled Product<p>Applications Protected form of FK-506 (Tacrolimus)<br>References Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., et al.: Brit. Med. J., 318, 1104 (1999),<br></p>Formula:C56H97NO12Si2Color and Shape:NeatMolecular weight:1032.54Ixabepilone- d3
CAS:Controlled ProductFormula:C27H39N2D3O5SColor and Shape:NeatMolecular weight:509.72
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