Carbohydrates and glycoconjugates

<p>Lacto-N-neotetraosa-APD-HSA is a synthetic monosaccharide that is structurally similar to tetrasaccharide and pentasaccharide. It can be synthesized by click chemistry and has been modified by fluorination and acetylation. Lacto-N-neotetraosa-APD-HSA has a high purity and is an excellent candidate for applications in the food industry, such as sugar substitutes.</p>

<p>Man-6 N-Glycan is a custom synthesis of an oligosaccharide. It is also classified as a polysaccharide and carbohydrate. The glycosylation of this product involves the addition of a sugar to the glycan, which is then modified by methylation or fluorination. This product has been shown to be stable in a buffer solution at pH 7 and can be used for click chemistry. The purity is high with no detectable impurities.</p>

<p>Gangliotriose is the core trisaccharide structure in gangliosides, such as, GD2 (GalNAcβ1,4Galβ1,4Glc) (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that posess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>N-acetyllactosamine is a monosaccharide that belongs to the group of n-acetyllactosamine. It can be found in the form of an agglutinin, lactose, and lectin. The conformation of this molecule is an equilibrium between its alpha and beta forms. The pyridine can act as an acid catalyst for the alpha conformation. There are two forms of this molecule: one synthesized from D-glucose and one synthesized from D-galactose. 1,6-Anhydro-4-O-b-D-galactopyranosyl-b-D-glucopyranose is synthesized from D-glucose. Oligosaccharides containing this molecule have been expressed in Saccharomyces cerevisiae cells and purified by affinity chromatography on columns that contain immobilized antibody to human serum albumin. This molecule has been shown</p>

<p>Glycyl-monosialyl,monofucosyllacto-N-neohexose I is a synthetic, fluorinated monosaccharide that has been modified with a glycosylation. This oligosaccharide is an important building block in the synthesis of complex carbohydrates. Glycyl-monosialyl,monofucosyllacto-N-neohexose I is used in the synthesis of polysaccharides and glycoproteins. It is also commonly used as a starting material for modifying other sugars with methylation or click chemistry. The CAS number for this compound is 144977-01-1. The molecular weight of this compound is 254.5 g/mol and it has a purity of 99% (HPLC).</p>

<p>1,3:1,4 b-Glucotriose (A) is a custom synthesis that is available with a purity of ≥98%. It is a fluorinated polysaccharide with a complex structure that can be modified to produce different variations. The methylation status of the compound can be customized as well. This product is an oligosaccharide and polysaccharide sugar that contains one glucose unit. It has been synthesized from the monosaccharide sugar and it can be used for chemical modification or for research purposes.</p>

<p>Paromamine trihydrochloride is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification of the chemical compound. Paromamine trihydrochloride is an Oligosaccharide and saccharide that has been Glycosylated. The Carbohydrate complex is made up of a number of sugar units that are linked together to form a polysaccharide. This Polysaccharide can be found in many plants and animals.</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-glucopyranoside is a custom synthetic product. It is a complex carbohydrate made of an oligosaccharide and polysaccharide. This product is modified with saccharide and methylation. Methyl 2-acetamido-2-deoxy 3 O-(2,3,4,6 tetra -O acetyl b -D galactopyranosyl) a D glucopyranoside has CAS number 62998 28 1 and its purity level is high. The fluorination of this compound provides it with an additional feature of being water soluble. The synthesis of this product involves the use of the sugar in order to produce glycosylations.</p>

<p>Gala1-3(Fuca1-2)Gal Conjugated to BSA on Fractogel with glycosylamine formation</p>

<p>Tetradecasaccharide dp14 is a custom-synthesized, fluorinated, methylated, and modified saccharide. Tetradecasaccharide dp14 has been shown to have a variety of biological activities that are dependent on the type of modification. For example, this compound inhibits the enzyme alpha-glucosidase in vitro and in vivo. This enzyme is responsible for breaking down complex carbohydrates into simple sugars. Tetradecasaccharide dp14 also has anti-inflammatory properties and can be used as an antifungal agent against Candida albicans.</p>

<p>3'-a-Sialyl-N-acetyllactosamine-sp-biotin is a custom synthesis, modification, fluorination, methylation, monosaccharide, synthetic, click modification, oligosaccharide, saccharide and polysaccharide. It has CAS No. 870892-22-1 and a molecular weight of 590. It is used to modify proteins with glycosylation sites.</p>

<p>Galα(1-3) N-glycan is a glycoconjugate that is an oligosaccharide with a galactose residue at the nonreducing end of the glycan. It has been synthesized using Click chemistry to introduce fluorination and methylation. Galα(1-3) N-glycan is an important model for studying the biological function of glycosylations in humans. It has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This product is custom synthesis, high purity, and CAS No. 115973-45-0.</p>

<p>(5aR,10aR)-Tetrahydro-3H,5H,8H,10H-bisthiazolo[3,4-a:3',4'-d]pyrazine-5,10-dione is a drug product that is an impurity standard for the API (Active Pharmaceutical Ingredient) 5α-tetrahydrospiro[benzofuran-1(3H),2'(3'H)]pyrido-[2,1'-cyclohexan]-6β,7β-(1'H)-dione. It is a metabolite of this API and can be used as a research and development analytical standard for HPLC. The CAS number for this compound is 72744-67-3. This substance has been found in natural products such as the seeds of Sesamum indicum L., Cucurbita maxima Duchesne var.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-galactofuranosyl)-D-glucopyranose is a carbohydrate that belongs to the class of disaccharides. It is a member of the family of b-D-galactofuranosides, which are derived from the hydrolysis of glycosidic linkages in b-D-galactopyranose. 2A2DDG has been shown to interact with sulfate groups and nonreducing sugars. The interaction between 2A2DDG and sulfate groups may be due to the presence of hydroxyl group on the molecule's side chain. The disaccharide can be used as an analogue for glycosylation experiments, such as those involving glycosyltransferases or glycosidases.</p>

<p>(S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.</p>

<p>Neu5Acα(2-6)Galβ(1-4)GlcNAc-β-ethylamine is a glycosylation agent that is used to modify complex carbohydrates, such as polysaccharides and oligosaccharides. This product is a custom synthesis, which may be modified according to customer specifications. These modifications include methylation, click modification, fluorination, and saccharide modification. The desired purity of this product can be determined by the level of fluorescence in the solution.</p>

<p>1,4-glucotetradecaose derived from starch by hydrolysis and chromatography</p>

<p>4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is a synthetic, water soluble, non-digestible oligosaccharide. It has regulatory effects on the utilisation of glucose and lacto-n-neotetraose by various cells in vitro. This compound also inhibits the development of intestinal pathogens in humans and elucidates their sequence specificity. 4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is used to study the role of this molecule in infant nutrition.</p>

<p>The P1-antigen is a blood group antigen that is encoded by the gene. It is synthesized as a precursor protein of approximately 150 amino acids that undergoes proteolytic processing to generate two peptides, A and B, which are attached to the cell surface. The P1-antigen has been shown to be involved in transcriptional regulation and antimicrobial activity. It has also been shown to be present in metastatic colorectal cancer cells and its expression can be induced by trypsin treatment. The P1-antigen is also one of the most frequently studied proteins for its role in immune responses against bacteria, viruses, and parasites. This protein has been found to have response elements for several transcription factors including NF-κB, AP-1, NFAT, SP-1, and STAT3. The basic structure of this protein contains a diode region with two negatively charged regions that are critical for its function.</p>