Carbohydrates and glycoconjugates

<p>Monofucosyl-para-lacto-N-hexaose I is an oligsaccharide that is found in human milk</p>

<p>4-Deoxy-D-chitobiose heptaacetate is a synthetic compound that has been modified by the addition of a heptaacetate group. This modification provides an additional site for attachment to other molecules, such as nucleic acids or proteins. The fluorination of this saccharide provides further protection against degradation and increases its stability in aqueous solutions. 4-Deoxy-D-chitobiose heptaacetate is available in high purity and can be custom synthesized to meet your needs.</p>

<p>4-Methoxyphenyl 2,4-di-O-benzoyl-3-O-benzyl-6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl)-3,5-dideoxy--D glycero--alpha--D galacto--2 nonulopyranosylonate) -beta D galactopyranoside is a carbohydrate that is custom synthesized for the modification of saccharides. It has a molecular weight of 1066.81 g/mol and is soluble in water. 4MPB is used as an intermediate for the synthesis of other carbohydrates.</p>

<p>Penta-guluronic acid sodium salt (1,4-linked α-L-sodium guluronopentaose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences. This oligosaccharide can be released by acid hydrolysis (Shimokawa, 1996) and a number of biological activities have been discussed in a recent review (Xing, 2020).</p>

<p>2-Acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4-O-acetyl-6-O-(2,3,4,6-tetra-O-benzoyl-b-D -galactopyranosyl)-2 deoxy a D galactopyranosyl Fmoc threonine tert butyl ester is a custom synthesis with high purity and custom synthesis. This product is recommended for methylation and glycosylation reactions. It is a complex carbohydrate that has been modified by fluorination and saccharide.</p>

<p>Blood group antigen derivative with spacer arm</p>

<p>Fluorogenic substrate is used for detection of hyaluronidase activity. Urinary hyaluronidase activity is elevated in patients with intermediate and high grade bladder cancer; the expression of hyaluronidase and hyaluronan synthase-1 mRNA in malignant tissue can predict bladder cancer metastasis and disease recurrence (Kramer, 2011). These findings underscore the potential utility of the hyaluronidases to serve as biomarkers for bladder cancer. A novel fluorescent substrate labelled with two dyes: fluorescein as a green donor fluorophore, and rhodamine B as a red acceptor fluorophore, was therefore developed to measure hyaluronidase enzyme kinetics (Zhang, 2008). It was then demonstrated that simultaneous measurements of green and red emission of HA–FRET could be used to measure hyaluronidase presence and activity (Fudala, 2011).</p>

<p>Lewis Y tetrasaccharide-sp-biotin is a biotinylated oligsaccharide</p>

<p>Hyaluronate fluorescein is a synthetic glycosaminoglycan. It is modified with fluorine and can be used for labeling proteins, lipids, and nucleic acids. This product has a molecular weight of about 1000kDa.</p>

<p>GM2-Oligosaccharide-spacer-NH2 ammonium is a complex carbohydrate with an oligosaccharide spacer and a hydrophobic NH2 group. The product is custom synthesized to your specifications and is available in high purity. It can be modified with fluorination or click chemistry. GM2-Oligosaccharide-spacer-NH2 ammonium is used in the synthesis of polysaccharides, saccharides, and carbohydrates. Some of its applications include modifying proteins, monosaccharides, and sugars.</p>

<p>Benzyl 4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-2,3-di-O-benzylb -D-galactopyranoside is a Fluorination and Glycosylation product. It is a Custom Synthesis of Monosaccharide and Oligosaccharide. The CAS number for this product is 106835-99-8.</p>

<p>A3 N-Glycan is a glycosylation profile marker that is specific for the cancer cells. It discriminates between healthy and cancerous cells, which has been shown by analyzing the A3 N-glycan profiles in human plasma samples. The A3 N-glycan marker is detected using high performance liquid chromatography (HPL) analysis. This assay can be used to diagnose cancer and monitor its progression.</p>

<p>Man-3-F N-Glycan is a custom synthesis of an oligosaccharide. It is a polysaccharide that is modified with methylation, glycosylation and click modification. Man-3-F N-Glycan is a high purity product that has been fluorinated for use in synthetic biology.</p>

<p>Sialyl-Lex-hexa-APD-HSA is a high purity synthetic glycosylation that is custom synthesized. It has been modified with fluorination, methylation, and click modification. Sialyl-Lex-hexa-APD-HSA can be used in the synthesis of complex carbohydrates and is available in CAS Number: 75869-57-3.</p>

<p>Ex algal/bacterial polysaccharides-value in b1-3 glucanase assays &amp; diagnostics</p>

<p>This product is a complex carbohydrate that is used in the modification of oligosaccharides and polysaccharides. It is synthesized by reacting 4-O-(a-D-galactopyranosyl)-b-D-galactopyranosyl chloride with bovine serum albumin (BSA) under acidic conditions. The product has a purity of greater than 98% and a molecular weight of approximately 3,000 Daltons.</p>

<p>The Blood group H type II trisaccharide methyl ester is a synthetic oligosaccharide. It has been modified with fluorination, monosaccharide, and methylation. The Blood group H type II trisaccharide methyl ester is soluble in organic solvents such as acetone and methanol. It can be used to synthesize glycosylated polysaccharides and complex carbohydrates through the Click modification method.</p>

<p>O-[2-Acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-galactopyranosyl]-N -Fmoc--L--threonine allyl ester is a carbohydrate that can be custom synthesized. It is an Oligosaccharide with the following structure: The chemical formula is C36H60NO22 and the molecular weight is 752.8 g/mol. It has a CAS number of 384346–85–4 and it's Chemical Abstract Service (CAS) name is O-[2-(acetamido)-4,6-[O-(2,3,4,6 tetra‑O‑acetyl‑β‑D‑galactopyranosyl)‑α‑</p>

<p>Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP is a modified oligosaccharide with a carbohydrate backbone of 3 mannose and 1 galactose residues. The saccharide is synthesized from the monosaccharides methylated, glycosylated, and then fluorinated. Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP has a CAS number of 71769-77-5.</p>

<p>NA2G1F N-glycan is a modified glycopeptide that is synthesized from the monosaccharide chitin. It has been fluorinated to render it resistant to proteolytic degradation and has been glycosylated with sialic acid residues. NA2G1F N-glycan can be used for use in click chemistry, methylation, or glycosylation. The molecular weight of this product is between 5 and 50 kDa, with a purity of &gt; 98%.</p>