Carbohydrates and glycoconjugates

<p>A custom synthesis of benzyl-6-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-2,3,4-tri-O-benzyl-a-D-mannopyranoside was made with the following modifications: fluorination and methylation. The molecular weight is 636.81 g/mol. It is a white crystalline solid. CAS No.:</p>

<p>Lacto-N-neotetraose-GEL is a glycosylation product that is used in the synthesis of complex carbohydrates. It is a methylated, fluorinated, and saccharide-modified oligosaccharide. This product can be custom synthesized in high purity with a CAS number and has a very low endotoxin level. Lacto-N-neotetraose-GEL has been shown to have many uses including as an adjuvant for vaccines and monoclonal antibody production. It has also been shown to suppress inflammation and increase the efficacy of cancer treatments.</p>

<p>2,3,4,6-Tetra-O-acetyl-1-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-D-galactopyranoside is a glycosylated polysaccharide that has been modified by methylation and fluorination. It is synthesized from the monosaccharide D galactopyranose with a 2,3,4,6 tetra O acetyl group at the 1 position.</p>

<p>3'-a-Sialyl-N-acetyllactosamine-PAA-biotin is a biotin labelled sialylglycoside</p>

<p>Pinoresinol diglucopyranoside is a natural compound found in Chinese herb. It has been shown to have an anti-atherosclerotic effect, which may be due to the inhibition of nuclear factor kappa-light-chain-enhancer (NF-κB) and matrix metalloproteinase (MMP)-9. Pinoresinol diglucopyranoside also inhibits collagenase activity in vitro and reduces inflammation in vivo. The molecular mechanism of this compound may involve the toll-like receptor 4 (TLR4) pathway, which is responsible for immune responses to bacterial products. Pinoresinol diglucopyranoside has been shown to inhibit the transcription and polymerization of DNA by binding to DNA gyrase and topoisomerase IV, respectively.</p>

<p>Benzyl 2-acetamido-3-O-(2,3,4-tri-O-benzyl-a-L-fucopyranosyl)-4,6-O-benzylidene-2-deoxy-a-D-glucopyranoside is a high purity custom synthesis sugar. This compound has been synthesized by Click modification of the amino acid glycoside and fluorination of the sugar. It is an Oligosaccharide with a saccharide chain composed of Monosaccharides and Carbohydrates. The CAS number for this compound is 196941 – 73 – 8.</p>

<p>4-Methoxyphenyl 4-O-{4-O-[2,4-di-O-(3,4,6-tri-O-Ac-2-PhthN -bDGlc)-3,6-di-O-(3,4,6,-tri-OAc)aDMan]-bDMan} 3,6 di O-(3,4,6,-tri Ac) a D Man] 2 PhthN b D Glc} 6 O (tri Ac) a L Fuc} 2 PhthN b D Glc} 3 O Bn 6 O (tri Ac) a L Fuc} 2 PhthN b D Glc} is an oligosaccharide. It is custom synthesized to include methylation and glycosylation modifications. This product is for use in research only and should not be used in humans.</p>

<p>Essential component of lipopolysaccharide in most Gram-negative bacteria and the minimal structural component to sustain bacterial viability. It serves as the active component of lipopolysaccharide to stimulate potent host immune responses through the complex of Toll-like-receptor 4 and myeloid differentiation protein 2.</p>

<p>4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-1,2-ethyledine (CAS No. 230953-17) is a carbohydrate that has been modified with acetyl groups at the 3 and 6 positions of the monosaccharide unit. This modification is a complex carbohydrate that is made up of oligosaccharides and polysaccharides. The modification causes changes in the chemical properties of the carbohydrate compared to natural saccharides. 4-O-(2,3,4,6) tetra O acetyl a D mannopyranosyl 1 2 ethyledine b D mannopyranose has been used in synthesis of custom sugars for medical applications. It has also shown anti inflammatory activities against Mycobacterium tuberculosis and Mycobacterium avium complex</p>

<p>Glycyl-lacto-N-fucopentaose II is a synthetic glycosylation product. It has high purity and is easy to use in the synthesis of complex carbohydrates. This product can be fluorinated, methylated, or modified with click chemistry to generate a wide range of products. Glycyl-lacto-N-fucopentaose II is CAS No. 107834-53-2 and has a molecular weight of 707.5 Da.END&gt;&gt;</p>

<p>k-carrageenan derived heptasaccharide tetrasulfate+(3-6 anhydrogalactose)</p>

<p>Gala1-3Galb1-4(6-deoxyGlcNAc)-HSA is a custom synthesis of a complex carbohydrate. It is an oligosaccharide with CAS No. and Polysaccharide that has been modified by Methylation, Glycosylation, and Click modification. Carbohydrate is one of the most important macronutrients for human health, as it provides energy and cell building blocks. Sugar (e.g., glucose) is the simplest form of carbohydrate, while saccharide refers to chains of sugar molecules. Gala1-3Galb1-4(6-deoxyGlcNAc)-HSA has been fluorinated and synthesized with high purity in order to be used as a drug delivery system. This drug can be used to treat various diseases such as diabetes mellitus type I or II, cancer, or HIV/AIDS.</p>

<p>Reductive amination of memantine with disaccharide.</p>

<p>3-O-(2-Acetamido-2-deoxy-D-glucopyranosyl)-1,2-di-O-benzyl-4,6-O-benzylidene-D-mannopyranoside is a synthetic sugar that is used in the synthesis of glycosylations. It has been fluorinated and methylated to increase its stability and reactivity. It is also synthetically derived from a saccharide and modified for use in Click chemistry. 3-O-(2-Acetamido-2-deoxy--D--glucopyranosyl)-1,2--di--O--benzyl--4,6--O--benzylidene--D--mannopyranoside is soluble in water and ethanol. This product has CAS No. 5118876–78–3 and can be custom synthesized by us.</p>

<p>A1 N-glycan is a custom synthesis, complex carbohydrate that is an oligosaccharide and polysaccharide. It is modified with saccharides, methylation, glycosylation, and fluorination. A1 N-Glycan has high purity and is custom synthesized to order.</p>

<p>GQ1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, two sialic acids (NeuAc) linked α2,3/α2,8 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Anti-GQ1b ganglioside antibody is associated with Miller Fisher syndrome and is also found in patients with related conditions that may share the same pathogenic mechanism, such as, Bickerstaff brainstem encephalitis. Thus, the measurement of anti-GQ1b antibody in suspected cases of Miller Fisher syndrome is a useful diagnostic marker (Paparounas, 2004). It has been found that GQ1b ganglioside contributes to synaptic transmissions and synapse formation. Low concentrations of GQ1b ganglioside, evoked dopamine (DA) release from laboratory tissues (Chen, 2018).</p>

<p>Lacto-N-fucopentaose II-APD-HSA is a complex carbohydrate that has been chemically modified to include a fucose sugar. Lacto-N-fucopentaose II-APD-HSA is synthesized by the click reaction and then modified with the addition of an acetyl group. The product is then methylated and purified by HPLC. Lacto-N-fucopentaose II-APD-HSA can be used in a wide range of applications, including as a component in glycosylation reactions or as an adjuvant for fluorescence labelling.</p>

<p>Benzyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-a-D-glucopyranoside is a custom synthesis, complex carbohydrate. It is an Oligosaccharide, Polysaccharide that has been modified and glycosylated. It has a CAS number of 81243-70-1. This product's purity is high and it is fluorinated. The product is synthetic and contains sugar.</p>

<p>2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl serine (GalNAc) is a synthetic carbohydrate that contains a biotin moiety. It is synthesized by the glycosylation of 2,3,4,6 tetraacetamido sugar with 2,3,4,6 tetraacetamido sugar and 1,2,3 octaacetamido sugar. The product can be modified with methyl or fluorine groups to make it more reactive in click chemistry. This product has been shown to have high purity and can be used in custom synthesis projects.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-b-D-cellobiosyl azide is a sugar that belongs to the group of carbohydrates. It is modified with fluorination and glycosylation. The CAS number for this compound is 33012-50-9. 2,3,6,2',3',4',6'-Hepta-O-acetyl-b-D-cellobiosyl azide has been synthesized and its chemical modification has been studied. This compound has an average degree of polymerization (DP) of 10. The molecular weight of 2,3,6,2',3',4',6'-Hepta-O-acetyl-b -D -cellobiosyl azide is 569.27 g/mol.</p>