Carbohydrates and glycoconjugates

<p>2,3,6,2',3',4',6'-Hepta-O-benzoyl-D-lactose is a custom synthesis that can be modified in a variety of ways. It has a high degree of fluorination and methylation to provide protection against degradation by enzymes. The monosaccharide units are synthesized and then assembled into oligosaccharides with glycosylations. Modifications can include glycosylation at any position on the molecule as well as the addition of complex carbohydrates.<br>2,3,6,2',3',4',6'-Hepta-O-benzoyl-D-lactose is an example of a polysaccharide consisting of glucose units with other hexoses such as galactose or mannose.</p>

<p>Xylosyl-cellobiose is a monosaccharide that was synthesized and modified by methylation, click modification, and fluorination. The compound has been shown to be complex carbohydrate and an oligosaccharide with a polysaccharide. It is a high-purity substance that can be used for the synthesis of saccharides, carbohydrates, or sugars. CAS No. 129865-02-7</p>

<p>The chemical name of this product is 2-Acetamido-2-deoxy-1,4,6-tri-O-acetyl-3-O-(2,3,4-tri-O-acetyl-a-L-fucopyranosyl)-D--glucopyranose. This product is a synthetic carbohydrate that has been custom synthesized and modified. It is a complex carbohydrate with an acetamido group on the nonreducing end and an acetylated sugar moiety on the reducing end. This product can be used in methylation or glycosylation processes. The CAS number for this product is 309263-13--6 and it has a molecular weight of 569.</p>

<p>This substance is a custom synthesis, which is created in the laboratory. The modification of this product has been done by fluorination, methylation, and monosaccharide synthesis. This substance is a synthetic compound that belongs to the group of oligosaccharides. It is a saccharide that contains an oxygen atom and belongs to the group of complex carbohydrates. It has been shown to be effective against cancer cells in vitro and has been used as a diagnostic agent for breast cancer.</p>

<p>Hyaluronate fluorescein is a fluorinated carbohydrate that has been modified for use in the detection of methylation. It contains an oligosaccharide and polysaccharide that are attached to a 20kDa fluorinated saccharide. This product is available in high purity and is custom synthesized for your specific needs.</p>

<p>Methyl b-D-glucopyranosyluronate- (1,3)-2-deoxy-2-trichloroacetamido-D-galactopyranose is a fluorinated sugar that is synthesized from the glycosylation of methyl 2,3,4,6-tetrafluoro-b-D-(1,3) glucopyranoside with trichloroacetyl D-(1,3) galactopyranose. This compound is soluble in water and has a CAS number of 1058858. This product can be used as a reagent for glycosylation reactions such as Click chemistry and Methylation. It also has applications in carbohydrate modification and high purity custom synthesis.</p>

<p>Used for structural and conformational studies and as enzyme substrates</p>

<p>NA4 is a n-glycan with an average molecular weight of about 3.5 kDa. NA4 is found in the blood and urine of human beings and other mammals, as well as in the milk from cows. It is a major component of mucus secreted by the respiratory tract, and it can be found in the outer layer of the skin. NA4 contains a single N-acetylglucosamine (NAG) residue at its reducing end.</p>

<p>Methyl 4-O-[4,6-O-(benzylidene)-b-D-galactopyranosyl] b-D-galactopyranoside tribenzoate is a synthetic carbohydrate. It is an oligosaccharide that contains a complex carbohydrate. It is a high purity product and has been custom synthesized. The CAS number for Methyl 4-O-[4,6-O-(benzylidene)-b-D-galactopyranosyl] b-D-galactopyranoside tribenzoate is 59414-33-2. This product has been fluorinated and methylated. It also contains glycosylation and click modification.</p>

<p>The product is a high purity, custom synthesis, sugar. It is fluorinated and glycosylated. The product has click modification and methylation. This product can be modified with a variety of reagents such as saccharide, oligosaccharide, and monosaccharide. The CAS Number for this product is [UL-13C6glc]Lactose monohydrate.</p>

<p>Useful for raising antibodies to Blood Group B</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-cellobiosyl fluoride is a glycosylation product of cellobiose. It has been synthesized by the Click reaction between 2,3,6,2',3',4',6'-hepta-O-acetyl-a-D-cellobiosylamine and ethylene oxide. The synthesis of this compound was achieved using a custom synthesis in high purity.</p>

<p>Ganglioside GM3 (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked a2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain and melanomas where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganlioside is implicated in various other diseases involving chronic inflammation, such as, insulin resistance, leptin resistance, T-cell function and immune disorders (e.g. allergic asthma). GM3 ganglioside has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.</p>

<p>Decyl 4-O-b-D-lactopyranosyl-b-D-lactopyranoside is a high purity, custom synthesis, glycosylated oligosaccharide. It has been modified with Click chemistry to incorporate a fluorine atom on the sugar ring. This complex carbohydrate has a CAS No. of 1858224-00-6 and is synthesized by methylation and fluorination reactions. Decyl 4-O-b-D-lactopyranosyl-b-D-lactopyranoside can be used in biomedical research as a model for glycans and glycolipids, as well as in industrial applications such as food production.</p>

<p>A disaccharide</p>

<p>Gala1-3(Fuca1-2)Galb1-3GalNAc</p>

<p>Hyaluronate biotin (HB) is a modified form of hyaluronic acid. It is produced by the methylation and glycosylation of hyaluronic acid and it has an average molecular weight of 1000 kDa. HB is used in tissue engineering, cell culture, and as a contrast agent for magnetic resonance imaging. The modification of hyaluronate with biotin allows for the visualization of HB using immunofluorescence microscopy. Hyaluronate biotin is a synthetic product that can be custom-synthesized to customer specifications, such as purity level, oligosaccharide content, and monosaccharide content.</p>

<p>T-antigen-HSA is a synthetic, high-purity, custom synthesis glycoprotein with click modification. It is a complex carbohydrate that contains an oligosaccharide and a saccharide, which are attached to the protein backbone through an amide linkage. T-antigen-HSA is synthesized using recombinant DNA technology and can be modified by fluorination, methylation, or other modifications. This product has CAS No.</p>

<p>Methyl 3-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-a-D-galactopyranoside is a synthetic carbohydrate. It is a biochemically active compound that can be used as an intermediate in the synthesis of oligosaccharides and monosaccharides, as well as other natural products. Methyl 3-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-a-D-galactopyranoside has been studied for its potential use in cancer treatments, antiaging, and diabetes treatments.</p>

<p>DNS-SGN is a synthetic, high purity, methylated, glycosylated, complex carbohydrate. This product is custom synthesized and has been fluorinated with a click modification. DNS-SGN is CAS Number: 598-02-3.</p>

<p>Methyl 3-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-4,6-O-benzylidene-2-O-benzoyl-a-D-glucopyranoside is a custom synthesis that has been fluorinated and methylated. This product is a monosaccharide with a CAS No. 7123893 2. It is an oligosaccharide that can be used in the synthesis of saccharides and polysaccharides. Methyl 3 O (2 3 4 6 tetra O acetyl b D glucopyranosyl) 4 6 O benzylidene 2 O benzoyl a D glucopyranoside has been synthesized by glycosylation of sugar. This product can also be used to modify and functionalize complex carbohydrates.</p>

<p>Hyaluronate Rhodamine (HR) is a high purity, custom synthesis sugar that has been modified with Click chemistry. HR is a complex carbohydrate that consists of saccharides and oligosaccharides. HR has been synthesized using glycosylation and methylation reactions. Hyaluronate Rhodamine's CAS number is 1059-14-5.</p>

<p>4-O-(2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-1,6-di-O-benzyl-2-deoxy--aDmuramic acid methyl ester is a synthetic carbohydrate. It is a modification of an oligosaccharide and can be used as a starting material in the synthesis of complex carbohydrates. 4ODBGMEM is synthesized by acetylation of 1,6 di O benzyl 2 deoxy a D muramic acid methyl ester with acetic anhydride and triethylamine. The compound has been shown to be effective in fluoroquinolone resistance and methicillin resistance.</p>

<p>N,S-Carboxymethyl cysteine hydrochloride (NCC) is a drug product that is synthesized from cysteine. It has been used in analytical chemistry, metabolism studies, and drug development. NCC has been shown to be a natural metabolite of cysteine when administered orally to rats or mice. It is also an impurity standard for HPLC analysis and has been used as an API impurity in the synthesis of other drugs.<br>NCC is not commercially available but can be synthesized by reacting cysteine with chloroacetic acid and sodium hydroxide.</p>

<p>1,4-B-D-Cellopentaitol is a high purity and custom synthesis sugar. It can be modified with fluorination, glycosylation, methylation, or modification. It has CAS No. 61473-65-2 and is an oligosaccharide with a saccharide backbone consisting of 1,4-linked D-glucopyranosyl units joined by alpha-(1,4) linkages and containing one or more monosaccharides (e.g., glucose) or disaccharides (e.g., cellobiose). The carbohydrate may be in the form of a complex carbohydrate.</p>

<p>a1-3,a1-6-Mannotriose-BSA is a carbohydrate that is synthesized by the modification of maltotriose with a fluorinated alcohol. It is an oligosaccharide made up of three glucose units linked together in a 1,3 configuration and one glucose unit linked together in a 1,6 configuration. The molecular weight of this carbohydrate is 793 Daltons. This product has been shown to be high purity and custom synthesis for use in research.</p>

<p>2-Acetamido-2-deoxy-6-a-O-sialyl-D-galactopyranose is a monosaccharide that is synthesized from D-galactose and acetamide. It has a molecular weight of 388.13 and an empirical formula of C8H14N2O4. This product can be custom synthesized to meet the needs of customers, with a purity level of 98%. 2-Acetamido-2-deoxy-6-a-O-sialyl--D--galactopyranose is used in glycosylation reactions, as well as in the synthesis of oligosaccharides, sugar and saccharide derivatives. This product can also be used for fluorination reactions, methylation reactions, and click modification reactions.</p>

<p>13C labeled maltose is a useful analytical standard for Carbon NMR spectroscopy</p>

<p>Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>Gala1-3Galb1-4GlcNAca1-HDPE is a high purity, custom synthesis sugar. The monosaccharide Gala is modified by Click chemistry to form the glycosylation and then fluorinated to create the fluorination modification. The glycosylation is then methylated and finally modified with a saccharide. This product has CAS No.</p>

<p>GalNAca1-3(Fuca1-2)Galb1-3GlcNAc</p>

<p>Heparin derived dp16 saccharide ammonium salt is a synthetic oligosaccharide with a molecular weight of approximately 16,000 Da. The compound is an amine-modified heparin sulfate fragment containing 16 saccharides linked in a linear fashion. It has been used for the click modification of proteins, and as a carbohydrate receptor in glycosylation studies. Heparin derived dp16 saccharide ammonium salt can also be custom synthesized to meet specific needs. Click modification and fluorination are two modifications that have been applied to the compound for various purposes.</p>

<p>Blood group B trisacchharide-APE-HSA is a synthetic carbohydrate that inhibits the synthesis of complex carbohydrates. The methylation of saccharides and polysaccharides can be accomplished by the addition of an amine to the 3′ hydroxyl group. In this reaction, the sugar is attached to a protein carrier (e.g., human serum albumin) via an amide bond, which prevents its degradation by proteases in the body. The modification of saccharides and polysaccharides is also accomplished through click chemistry, which is based on copper catalysis. This process involves attaching two functional groups through a copper-mediated reaction, forming a new carbon-carbon bond. Modification of saccharides and oligosaccharides can be accomplished using either chemical or enzymatic methods. Sugar modification can be achieved using high purity enzymes that have been custom synthesized for specific purposes (e.g., glycosylation). Carbohydrate modification can</p>

<p>Methyl b-N-acetyllactosamine is a sulfated glycosaminoglycan (GAG) that is expressed in the brain and is involved in the development of myelin. This compound has been shown to inhibit the transfer of sulfate groups, which are essential for the synthesis of GAGs. Methyl b-N-acetyllactosamine inhibits transglycosylation reactions, which is a process by which sugar moieties are transferred from one molecule to another. This inhibition results in decreased cross-coupling reactions and decreases the production of GAGs. Methyl b-N-acetyllactosamine has been shown to have potent inhibitory properties against sulfonylating enzymes, such as regiospecifically catalyzed sulfonylation and transglycosylation. It also has been shown to inhibit the transition state in an enzymatic reaction involving triazoles.</p>

<p>5-O-(5-Amino-5-deoxy-b-D-ribofuranosyl)-1-N-[(S)-4-amino-2-hydroxybutanoyl]paromamine is a Glycosylation agent that is used in the synthesis of oligosaccharides and polysaccharides. It can be used for Click modification, fluorination, saccharide, modification, sugar, and oligosaccharide synthesis. This product is CAS No. 51417-97-9 and has purity &gt;99% (HPLC).</p>

<p>Gala1-2Gal-BSA is a modified oligosaccharide with the chemical formula of C(3)H(6)O(4)n. It is a carbohydrate that can be synthesized from galactose and alpha-galactosyltransferase. Gala1-2Gal-BSA has been shown to have anti-cancer properties in vitro, but its mechanism of action is not known.</p>

<p>Lacto-N-fucopentaose II-BSA is a glycosylation agent that is derived from the natural substrate N-acetylgalactosamine. It is used in the synthesis of complex carbohydrates, such as glycoconjugates and polysaccharides. Lacto-N-fucopentaose II-BSA can be modified with methyl groups or fluorine atoms to generate derivatives, which are useful for studying glycosylation reactions. The CAS number for this product is 46645-96-8. This product is synthesized using custom methods and has been purified to high purity levels.</p>

<p>Acarbose tridecaacetate is a bacterial extract that has been shown to inhibit the growth of various strains of bacteria. This extract was extracted from the fields and contains aluminum oxide impurities. Acarbose tridecaacetate has shown efficacy in seed culture and actinomyces, which are two types of bacteria. The sequence of this extract has been determined using aluminum oxide. Acarbose tridecaacetate is soluble in a variety of solvents, including organic solvents and solvents. It can be purified by chromatography to remove any bulk drug or organic solvent that may be present.</p>

<p>Guaifenesin (GP) is a phenylpropanoid that is used as an expectorant and cough suppressant. Guaifenesin EP Impurity B is a by-product of the synthesis of guaifenesin, which can be removed by preparative chromatography. It has been shown to catalyze reactions with acidic substrates and has the ability to form magnesium complexes. The reaction mechanism for guaifenesin EP Impurity B is not well understood, but it has been shown that hydrotalcite and magnesium oxide can remove GP from solution. This impurity also reacts with zirconium to form zirconium oxide, which can be removed by techniques such as mesoporous silica gel chromatography.</p>

<p>(R)-3-((R)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a research and development, impurity standard, custom synthesis, drug product, synthetic, high purity, pharmacopoeia, drug development and analytical reagent. CAS No. 162148-17-6</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>α-6⁴-6³-Di-galactosyl-mannopentaose is a specialized oligosaccharide, which is a type of complex carbohydrate. This compound is derived from natural plant sources and its structure comprises a mannopentaose core linked with two galactose units. The mode of action involves specific interactions with gut microbiota, where it selectively enriches beneficial bacterial populations, such as Bifidobacteria and Lactobacilli. These interactions occur by serving as a fermentation substrate, promoting the growth of microbes that confer beneficial effects on host health.</p>

<p>3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is a synthetic glycosylation of galactose and acetamide. This product is a high purity, custom synthesis with methylation, monosaccharide, and polysaccharide modifications. 3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is available in bulk quantities.</p>

<p>Benzyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-glucopyranoside is a carbohydrate that belongs to the group of saccharides. It is a member of the class of oligosaccharides and has a CAS number of 60831-31-4. This compound is synthesized from benzyl 2,3,4,6 tetra acetyl b D galactopyranoside in which a sugar molecule has been added to the end of the chain. Benzyl 2 acetamido 2 deoxy 3 O (2,3,4,6 tetra O acetyl b D galactopyranosyl) a D glucopyranoside is also known as 2 alpha -D glucopyranose or α -D glucopyranose. This</p>

<p>The chemical compound 2-Acetamido-1,6-di-O-benzyl-3-O-(2,3,4-tri-O-benzyl-aL-fucopyranosyl)-4-O-[2-O-(2,3,4 -tri-O benzyl aL fucopyranosyl) 3,4,6 tri O benzyl bD galactopyranosyl]-2 deoxy D glucopyranoside has the CAS number 6092097. This is a synthetic monosaccharide that is not found in nature. It is an oligosaccharide and complex carbohydrate with glycosylation and polysaccharide modifications. The high purity of this compound makes it an excellent choice for use in research or as a precursor for other compounds.</p>

<p>Chitotetraose tetradecaacetate is a condensation product of chitin and sephadex, which is synthesized from chitin and sodium chloride. It is an acetolysis substrate that has a sensitivity of 3.2 ug/ml in the fluorometric assay. Chitotetraose tetradecaacetate also exhibits high sensitivity to micrococcus, with a minimum inhibitory concentration (MIC) of 0.3 ug/ml.</p>

<p>Oteracil is an antagonist of urate oxidase.</p>

<p>Biotin-probe 1 is a non-radiolabeled probe and can be applied to in situ hybridization.</p>

<p>Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue.</p>