Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Found 2393 products of "Ketones and derivatives"
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3′,4′-Difluoropropiophenone
CAS:Formula:C9H8F2OPurity:97%Color and Shape:LiquidMolecular weight:170.1595′-Acetyl-2′-fluoro-3-methyl-[1,1′-biphenyl]-4-carbaldehyde
CAS:Purity:≥95%Molecular weight:256.2760011-(3-Bromo-4-(1H-imidazol-1-yl)phenyl)ethanone
CAS:Formula:C11H9BrN2OPurity:>97%Molecular weight:265.114′-Chloro-3′-(trifluoromethoxy)acetophenone
CAS:Formula:C9H6ClF3O2Color and Shape:SolidMolecular weight:238.594-Chloro-3-(trifluoromethyl)acetophenone
CAS:Formula:C9H6ClF3OPurity:98%Color and Shape:SolidMolecular weight:222.592′-(Trifluoromethyl)acetophenone
CAS:Formula:C9H7F3OPurity:98%Color and Shape:Low Melting SolidMolecular weight:188.1491-(3,4-Dimethylphenyl)ethanol
CAS:Controlled Product<p>Applications 1-(3,4-Dimethylphenyl)ethanol is an intermediate in the production of Medetomidine (M203250), α2-Adrenergic agonist. Sedative; analgesic.<br>References Kagechika, H., et al.: J. Med. Chem., 32, 1098 (1989), ; Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987),<br></p>Formula:C10H14OColor and Shape:NeatMolecular weight:150.2216,17-Dehydro Capsaicin
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications A dehydrogenated metabolite of Capsaicin (C175680).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glinsukon, T., et al.: Toxicon, 18, 215 (1980), Obach, R., et al.: Drug Metab. Dispos., 29, 1599 (2001), Reilly, C., et al.: Toxicol. Sci., 73, 170 (2003),<br></p>Formula:C18H25NO3Color and Shape:Off-White To BrownMolecular weight:303.41-(2,5-Dimethylphenyl)ethanol
CAS:Controlled Product<p>Applications 1-(2,5-Dimethylphenyl)ethanol can be used as a reagent in reactions or as a aroma compound<br>References Zhou, J., et al.: Yuanyi Xuebao., 37, 1621-1628 (2010)<br></p>Formula:C10H14OColor and Shape:NeatMolecular weight:150.22(S)-(+)-Ibuprofen 2-(Benzyloxy)propan-1-yl Ester
Controlled Product<p>Applications (S)-(+)-Ibuprofen 2-(Benzyloxy)propan-1-yl Ester is an intermediate in the synthesis of (S)-(+)-Ibuprofen Propylene Glycol Ester (I140100), a derivative of (S)-(+)-Ibuprofen (I140010), a nonsteroidal anti-inflammatory drug (NSAID).<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C23H30O3Color and Shape:NeatMolecular weight:354.483Trimebutine EP Impurity E-Nitroso
Controlled ProductFormula:C21H26N2O6Color and Shape:NeatMolecular weight:402.441(S)-(+)-Ibuprofen Propylene Glycol Ester
CAS:Controlled ProductFormula:C16H24O3Color and Shape:NeatMolecular weight:264.36N-Desethyl 3-Bromo Lidocaine
CAS:Controlled Product<p>Applications Intermediate in the preparation of hydroxylated Lidocaine metabolites.<br></p>Formula:C12H17BrN2OColor and Shape:NeatMolecular weight:285.18D 13223-d4 (Flupirtine Metabolite)
CAS:Controlled Product<p>Applications The major active labelled metabolite of Flupirtine in human plasma. A potassium channel opener<br>References Niebch, G., et al.: Arzneim.-Forsch., 42, 1343 (1992), Friedel, H., et al.: Drugs, 45, 548 (1993), Fu, I., et al.: J. Pharm. Biomed. Anal., 18, 347 (1998),<br></p>Formula:C14H12D4ClFN4OColor and Shape:NeatMolecular weight:314.786,6'-Dimethoxy-2,2'-binaphthalene
CAS:Controlled Product<p>Applications 6,6'-Dimethoxy-2,2'-binaphthalene, can be used for the synthesis of novel classes of non-steroidal substrate mimetics, as inhibitors of human CYP17. It is also an impurity of Nabumetone (N200500), a non-steroidal anti-inflammatory drug, acting as anti-inflammatory agent.<br>References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006); Pinto-Bazurco, M. A. E., et al.: Bioorg. Med. Chem. Lett., 18, 267 (2008);<br></p>Formula:C22H18O2Color and Shape:NeatMolecular weight:314.38(±)-Carisoprodol-d7 (iso-propyl-d7)
CAS:Controlled Product<p>Applications (±)-Carisoprodol-d7 (iso-propyl-d7) (CAS# 1218911-01-3) is a useful isotopically labeled research compound. As a deuterated drug analog, this compound can be used for inter-patient variability.<br>References Gant, T., et.al., U.S. Pat. Appl. Publ., 28,(2010);<br></p>Formula:C12H17D7N2O4Color and Shape:NeatMolecular weight:267.38Nabumetone-d3
CAS:Controlled Product<p>Applications Labelled Nabumetone. Anti-inflammatory. Antibacterial.<br>References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006),<br></p>Formula:C152H3H13O2Color and Shape:NeatMolecular weight:231.30Methyl 5-Methoxy-2-methylindole-3-acetate
CAS:Controlled Product<p>Applications Intermediate in the preparation of Indomethacin<br>References Kalgutkar, A.S., et al.: Bioorg. Med. Chem., 13, 6810 (2005),<br></p>Formula:C13H15NO3Color and Shape:NeatMolecular weight:233.26(+)-N,O-Didesmethyl Tramadol
CAS:Controlled Product<p>Applications An optically active metabolite of Tramadol.<br>References Garrido, M., et al.: J. Pharmacol. Exp. Ther., 305, 710 (2003), Pedersen, R., et al.: Eur. J. Clin. Pharmacol., 62, 513 (2006),<br></p>Formula:C14H21NO2Color and Shape:NeatMolecular weight:235.324-Morpholineethanol-d4
CAS:Controlled Product<p>Applications Labelled analogue 4-(2-Hydroxyethyl)morpholine, a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary culture/DNA.<br></p>Formula:C6H9D4NO2Color and Shape:NeatMolecular weight:135.20L-Propoxyphene-d5 HCl (propionyl-d5)
CAS:Controlled Product<p>Applications L-Propoxyphene-d5 Hydrochloride is the isotope labelled analog and L-isomer of Propoxyphene Hydrochloride (P831500); a controlled substance (opiate) and analgesic (narcotic). The α-DL-and D-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive. Oral administration of L-Propoxyphene Hydrochloride enhances the analgesic activity of D-Propoxyphene Hydrochloride.<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971); McEwan, B., et al.: Anal. Profiles Drug Subs., 1, 301 (1972); Murphy, P.J., et al.: J. Pharmacol. Exp. Ther., 199, 415 (1976)<br></p>Formula:C22H25D5ClNO2Color and Shape:NeatMolecular weight:380.965-(6-Methoxy-2-naphthalenyl)-3-methyl-2-cyclohexen-1-one
CAS:Controlled ProductFormula:C18H18O2Color and Shape:NeatMolecular weight:266.332,2-Dimethoxy-2-phenylacetophenone
CAS:<p>Applications 2,2-Dimethoxy-2-phenylacetophenone (cas# 24650-42-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C16H16O3Color and Shape:White PowderMolecular weight:256.30Ketoprofen-13CD3 Methyl Ester
CAS:Controlled Product<p>Applications An intermediate for the synthesis of Labelled Ketoprofen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Derewenda, Z., et al.: J. Mol. Biol., 227, 818 (1992), Grochulski, P., et al.: J. Biol. Chem., 268, 12843 (1993).<br></p>Formula:C1613CH13D3O3Color and Shape:NeatMolecular weight:272.32N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide
CAS:Controlled ProductFormula:C12H14N4O2Color and Shape:NeatMolecular weight:246.27rac-2’,4’-Dimethyl Ketoprofen
CAS:Controlled Product<p>Applications rac-2’,4’-Dimethyl Ketoprofen is an impurity of Ketoprofen (K200800), an anti-inflammatory and analgesic agent.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Formula:C18H18O3Color and Shape:NeatMolecular weight:282.333-(Cyanomethyl)benzoic Acid
CAS:Controlled Product<p>Impurity Ketoprofen EP Impurity H<br>Applications 3-(Cyanomethyl)benzoic Acid (Ketoprofen EP Impurity H) is a reagent used in the synthesis of various pharmaceutically important compounds, such as its use in the synthesis of neprilysin inhibitors.<br>References Solomon, S.D., et al.: Lancet., 380 1387 (2012); Dadd, M.R., et al.: Enzyme. Microb. Tehcnol., 29, 20 (2001);<br></p>Formula:C9H7NO2Color and Shape:NeatMolecular weight:161.16Nabumetone Dimer Impurity
CAS:Controlled Product<p>Impurity Nabumetone Dimer Impurity<br>Applications An impurity in a Nabumetone (N200500) drug substance.<br>References Friedel, H., et al.: Drugs, 35, 504 (1988), Davies, N., et al.: Clin. Pharmacokinet., 33, 403 (1997),<br></p>Formula:C27H26O3Color and Shape:NeatMolecular weight:398.49R-(-)-Norapomorphine Hydrochloride
CAS:Controlled Product<p>Applications An Apomorphine derivative as inhibitor of amyloid-β (Aβ) fibril formation and their use in amyloidosis based disease.<br>References Howlett, D., et al.: Biochem. J., 340, 283 (1999), Kuner, P., et al.: J. Biol. Chem., 275, 1673 (2000), Ono, K., et al.: J. Neurosci. Res., 75, 742 (2004),<br></p>Formula:C16H15NO2•HClPurity:>90%Color and Shape:NeatMolecular weight:253.303646(-)-N-Desmethyl Tramadol
CAS:Controlled Product<p>Applications An optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C15H23NO2Color and Shape:NeatMolecular weight:249.352-Hydroxy Nabumetone
CAS:Controlled ProductFormula:C15H18O2Color and Shape:White To Off-WhiteMolecular weight:230.303-(6-Methoxy-2-naphthalenyl)-5-methylcyclohexanone (Impurity)
CAS:Formula:C18H20O2Color and Shape:NeatMolecular weight:268.35Trimebutine-d9 Maleate Salt
CAS:Controlled Product<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C22H20D9NO5·C4H4O4Color and Shape:NeatMolecular weight:512.63-Methoxy Acetaminophen-d3
CAS:Controlled Product<p>Applications 3-Methoxy Acetaminophen-d3 is deuterium labeled 3-Methoxy Acetaminophen (M226050). 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C92H3H8NO3Color and Shape:NeatMolecular weight:184.207(±)-Ibuprofen-d3, Sodium Salt (α-methyl-d3)
CAS:Controlled Product<p>Applications (±)-Ibuprofen-d3, Sodium Salt (alpha-methyl-d3) (CAS# 1219805-09-0) is a useful isotopically labeled research compound.<br></p>Formula:C13H14D3NaO2Color and Shape:NeatMolecular weight:231.294'-Isobutyl-2,2-dibromopropiophenone
CAS:Controlled Product<p>Applications Intermediate in the synthesis of Ibuprofen.<br></p>Formula:C13H16Br2OColor and Shape:NeatMolecular weight:348.073,4-Methylenedioxy Propiophenone
CAS:Controlled Product<p>Applications Intermediate in the production of Isosafrole and Ethylone.<br>References Katoch-Rouse, R., et al.: J. Med. Chem., 46, 642 (2003), Andrade, E., et al.: Chem. Biodivers., 5, 197 (2008),<br></p>Formula:C10H10O3Color and Shape:NeatMolecular weight:178.18Nabumetone dimer
CAS:<p>Nabumetone is a nonsteroidal anti-inflammatory drug that is metabolized by the liver to form a dimer. The major metabolite of nabumetone is the dimer, which has been used as an impurity standard for this drug. Nabumetone has been shown to inhibit prostaglandin synthesis, and its metabolites have been studied for their effects on various enzymes.</p>Formula:C27H26O3Purity:Min. 95%Molecular weight:398.49 g/mol
![5′-Acetyl-2′-fluoro-3-methyl-[1,1′-biphenyl]-4-carbaldehyde](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF628194.webp&w=3840&q=75)
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![1-[3-(ACETYLOXY)-4-METHOXYPHENYL]-ETHANONE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF467729.webp&w=3840&q=75)
