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Ketones and derivatives

Ketones and derivatives

Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.

Found 2399 products of "Ketones and derivatives"

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  • Nabumetone Dimer Impurity

    Controlled Product
    CAS:

    Impurity Nabumetone Dimer Impurity
    Applications An impurity in a Nabumetone (N200500) drug substance.
    References Friedel, H., et al.: Drugs, 35, 504 (1988), Davies, N., et al.: Clin. Pharmacokinet., 33, 403 (1997),

    Formula:C27H26O3
    Color and Shape:Neat
    Molecular weight:398.49

    Ref: TR-N200515

    10mg
    235.00€
    50mg
    1,046.00€
    100mg
    1,623.00€
  • 3,4-Methylenedioxy Propiophenone

    Controlled Product
    CAS:

    Applications Intermediate in the production of Isosafrole and Ethylone.
    References Katoch-Rouse, R., et al.: J. Med. Chem., 46, 642 (2003), Andrade, E., et al.: Chem. Biodivers., 5, 197 (2008),

    Formula:C10H10O3
    Color and Shape:Neat
    Molecular weight:178.18

    Ref: TR-M304050

    1g
    92.00€
    5g
    98.00€
  • N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide

    Controlled Product
    CAS:
    Formula:C12H14N4O2
    Color and Shape:Neat
    Molecular weight:246.27

    Ref: TR-D982010

    25mg
    124.00€
    250mg
    904.00€
  • D 13223-d4 (Flupirtine Metabolite)

    Controlled Product
    CAS:

    Applications The major active labelled metabolite of Flupirtine in human plasma. A potassium channel opener
    References Niebch, G., et al.: Arzneim.-Forsch., 42, 1343 (1992), Friedel, H., et al.: Drugs, 45, 548 (1993), Fu, I., et al.: J. Pharm. Biomed. Anal., 18, 347 (1998),

    Formula:C14H12D4ClFN4O
    Color and Shape:Neat
    Molecular weight:314.78

    Ref: TR-D100067

    25mg
    1,572.00€
    50mg
    2,735.00€
    2500µg
    236.00€
  • Acetaminophen-d3

    Controlled Product
    CAS:

    Applications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
    References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

    Formula:C82H3H6NO2
    Color and Shape:White
    Molecular weight:154.18

    Ref: TR-A161221

    1mg
    202.00€
    10mg
    609.00€
    2500µg
    284.00€
  • 3-Methylbenzophenone

    CAS:

    Applications 3-Methylbenzophenone (cas# 643-65-2) is a useful research chemical.

    Formula:C14H12O
    Color and Shape:Neat
    Molecular weight:196.24

    Ref: TR-M454545

    50mg
    83.00€
    100mg
    98.00€
    500mg
    118.00€
  • 16,17-Dehydro Capsaicin

    Controlled Product
    CAS:

    Stability Light Sensitive
    Applications A dehydrogenated metabolite of Capsaicin (C175680).
    Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
    References Glinsukon, T., et al.: Toxicon, 18, 215 (1980), Obach, R., et al.: Drug Metab. Dispos., 29, 1599 (2001), Reilly, C., et al.: Toxicol. Sci., 73, 170 (2003),

    Formula:C18H25NO3
    Color and Shape:Off-White To Brown
    Molecular weight:303.4

    Ref: TR-D229325

    1mg
    776.00€
    5mg
    3,012.00€
    500µg
    473.00€
  • rac-N-Desmethyl N-nitroso Tramadol-d3


    Formula:C15H19D3N2O3
    Color and Shape:Neat

    Ref: TR-D518441

    5mg
    To inquire
    50mg
    To inquire
  • (+)-N,O-Didesmethyl Tramadol

    Controlled Product
    CAS:

    Applications An optically active metabolite of Tramadol.
    References Garrido, M., et al.: J. Pharmacol. Exp. Ther., 305, 710 (2003), Pedersen, R., et al.: Eur. J. Clin. Pharmacol., 62, 513 (2006),

    Formula:C14H21NO2
    Color and Shape:Neat
    Molecular weight:235.32

    Ref: TR-D441230

    5mg
    1,472.00€
  • Methyl 5-Methoxy-2-methylindole-3-acetate

    Controlled Product
    CAS:

    Applications Intermediate in the preparation of Indomethacin
    References Kalgutkar, A.S., et al.: Bioorg. Med. Chem., 13, 6810 (2005),

    Formula:C13H15NO3
    Color and Shape:Neat
    Molecular weight:233.26

    Ref: TR-M320480

    10mg
    188.00€
    25mg
    236.00€
    50mg
    437.00€
  • 4-Acetaminophen-d3 Sulfate Potassium Salt

    Controlled Product
    CAS:

    Applications 4-Acetaminophen-d3 Sulfate Potassium Salt is a deuterium labeled metabolite of Acetaminophen (A161220) (1,2,3).
    References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961)(2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)

    Formula:C8H5D3KNO5S
    Color and Shape:Neat
    Molecular weight:272.33

    Ref: TR-A161232

    10mg
    1,663.00€
  • 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic

    CAS:
    5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic (5BPC) is a drug that is used for the treatment of pain. It has been shown to be safe and effective in treating postoperative pain when given by intravenous infusion or as an oral tablet. 5BPC has minimal toxicity and is metabolized primarily by the liver with a half life of 2.6 hours. The drug has been found to have pharmacokinetic properties that allow it to be used safely in patients with hepatic impairment and in those recovering from abdominal surgery. 5BPC is a prodrug that undergoes biotransformation by esterases into its active form, pyrrolizidine alkaloid (PA). PA acts as a nonsteroidal anti-inflammatory agent and inhibits prostaglandin synthesis, which leads to analgesia. This drug also has minimal drug interactions because
    Formula:C15H13O3N
    Purity:Min. 95%
    Molecular weight:255.27 g/mol

    Ref: 3D-IB58062

    25mg
    307.00€
    50mg
    491.00€
    100mg
    698.00€
  • Pelubiprofen

    CAS:
    Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.
    Formula:C16H18O3
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:258.31

    Ref: TM-T16464

    2mg
    34.00€
    5mg
    50.00€
    10mg
    80.00€
    25mg
    137.00€
    50mg
    215.00€
    100mg
    340.00€
    500mg
    795.00€
  • 3-Carboxy-a-methyl-benzeneacetic acid

    CAS:

    3-Carboxy-a-methyl-benzeneacetic acid (3CMA) is an impurity in the synthesis of 3,4-methylenedioxyphenylacetone. It is a preservative that has been analysed as a potential source of contamination in pharmaceutical preparations. 3CMA has been shown to be effective at inhibiting the growth of bacteria, yeast and moulds. The analysis time for 3CMA is typically 8 hours or less. The parameters that are used to analyse 3CMA include the use of acetonitrile, optimal porosity and efficiency. The analytical methods used for 3CMA include chromatographic and chromolith methods.

    Formula:C10H10O4
    Purity:Min. 95%
    Molecular weight:194.18 g/mol

    Ref: 3D-IC19808

    5mg
    673.00€
    10mg
    1,020.00€
    25mg
    1,982.00€
    50mg
    2,925.00€
  • N-(4-Hydroxyphenyl)propanamide

    CAS:
    The N-(4-hydroxyphenyl)propionamide (HPPA) is a synthetic drug that binds to the human liver. It has been shown to be effective in preventing implantation of fertilized eggs, and can be used as a diagnostic agent for determining the presence of HPPA in human liver tissue. HPPA is also used as a diluent for other drugs. The HPPA binds to chromatographic components and can be detected using electrochemical detection, which allows it to be used as a targetable probe for cancer research. HPPA is also used to study iontophoretic transport of ions across reconstituted membranes in vitro.
    Formula:C9H11NO2
    Purity:(%) Min. 97%
    Molecular weight:165.19 g/mol

    Ref: 3D-IP27203

    5mg
    322.00€
    10mg
    454.00€
    25mg
    673.00€
    50mg
    1,020.00€
    100mg
    1,322.00€
  • N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium

    Controlled Product
    CAS:
    Please enquire for more information about N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Formula:C8H6D3NO5S•Na
    Purity:Min. 95%
    Molecular weight:257.24 g/mol

    Ref: 3D-IH183408

    1mg
    305.00€
    2mg
    322.00€
    5mg
    538.00€
    10mg
    740.00€
  • (2-Amino-2-(hydroxymethyl)propane-3-ol-1-yl) (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate), racemic


    Racemic 2-amino-2-(hydroxymethyl)propane-3-ol-1-yl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate) is a synthetic drug product. It is used in research and development as an impurity standard. It is also used to synthesize drug products, which are custom synthesis and not commercially available. The racemate is a metabolite of the natural compound "Lysergic acid" and has been studied for its effects on metabolism.
    Formula:C19H22N2O5
    Purity:Min. 95%
    Molecular weight:358.39 g/mol

    Ref: 3D-IA58064

    1g
    300.00€
    2g
    349.00€
    5g
    598.00€
    10g
    1,067.00€
  • Nabumetone dimer

    CAS:
    Nabumetone is a nonsteroidal anti-inflammatory drug that is metabolized by the liver to form a dimer. The major metabolite of nabumetone is the dimer, which has been used as an impurity standard for this drug. Nabumetone has been shown to inhibit prostaglandin synthesis, and its metabolites have been studied for their effects on various enzymes.
    Formula:C27H26O3
    Purity:Min. 95%
    Molecular weight:398.49 g/mol

    Ref: 3D-IN26116

    1mg
    188.00€
    2mg
    290.00€
    5mg
    378.00€
    10mg
    538.00€
    25mg
    1,020.00€
  • 6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic

    CAS:
    6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic is a drug product that is used as an analytical standard in the development of new drugs. It is also used to study the metabolism of drugs. 6BPDC has been shown to inhibit bacterial growth by binding to DNA and RNA, thereby preventing transcription and replication. This metabolite can be synthesized in the laboratory.
    Formula:C15H13NO3
    Purity:Min. 95%
    Molecular weight:255.27 g/mol

    Ref: 3D-IB58058

    1mg
    354.00€
    2mg
    474.00€
    5mg
    740.00€
    10mg
    1,057.00€
    25mg
    1,652.00€
  • Tramadol Related Compound A CIV ((RS,SR)-1-(3-Methoxyphenyl)-2-(dimethylaminomethyl)cyclohexanol hydrochloride)

    Controlled Product
    CAS:
    Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function
    Formula:C16H25NO2·HCl
    Color and Shape:White Powder
    Molecular weight:263.18853