Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10345 products of "Benzimidazole and Imidazole Derivatives"
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Tert-Butyl 4-(3-iodo-1H-indazol-6-yl)piperazine-1-carboxylate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:428.273986816406255-(4-methylphenyl)-1-[2-(propan-2-yl)phenyl]-2,3-dihydro-1H-imidazole-2-thione
CAS:Purity:97%Molecular weight:308.440002441406252-(1H-Imidazol-2-yl)phenol
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:160.175994873046882-cyclopropyl-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:158.20399475097656(S)-Modafinil
CAS:Controlled Product<p>Applications Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219 (2002), Dinges, D., et al.: Curr. Med. Res. Opin., 22, 159 (2006)<br></p>Formula:C15H15NO2SColor and Shape:NeatMolecular weight:273.355-Phenylthio-2-aminobenzimidazole
CAS:Controlled Product<p>Applications 5-Phenylthio-2-aminobenzimidazole, is a derivative of Fenbendazole (F246750), an anthelmintic.<br>References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),<br></p>Formula:C13H11N3SColor and Shape:Light Brown To OrangeMolecular weight:241.31Rufinamide-d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N4OColor and Shape:White To Light YellowMolecular weight:240.21Iminodibenzyl 5-Carbonyl Chloride
CAS:Controlled ProductFormula:C15H12ClNOColor and Shape:NeatMolecular weight:257.71Omeprazole
CAS:Controlled Product<p>Applications Omeprazole covalently binds to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O3SColor and Shape:White To Light BrownMolecular weight:345.42(S)-Luliconazole
CAS:Controlled Product<p>Applications (S)-Luliconazole is the (S)--enantiomer of Luliconazole, an azole antifungal drug. Luliconazole was found to interfere with ergosterol biosynthesis in cell-free extracts of Candida albican, while no interference due to (S)-Luliconazole was found.<br>References Uhida, K., et al.: J. Infect. Chemother., 10, 216 (2004); Niwano, ., et al.: Antimicro. Agents Chemother., 42, 967 (1998); Niwanno, Y., et al.: Med. Mycol., 37, 351 (1999)<br></p>Formula:C14H9Cl2N3S2Color and Shape:NeatMolecular weight:354.28Isometronidazole
CAS:Controlled Product<p>Impurity Metronidazole EP Impurity E<br>Applications Isometronidazole (Metronidazole EP Impurity E) is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6H9N3O3Color and Shape:NeatMolecular weight:171.156-O-Desmethyl Donepezil-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.<br>References De Vos, F., et al.: Nuc. Med. Biol., 27, 745 (2000), Okereke, C., et al.: Brit. J. Clin. Pharmacol., 58, 41 (2004),<br></p>Formula:C232H5H22NO3Color and Shape:NeatMolecular weight:370.502-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole
CAS:Controlled Product<p>Applications 2-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole is an impurity of Ornidazole (O688500) which has antifertility activity.<br>References Jones, A., et al.: Xenobiotica, 27, 711 (1997); Cooper, T., et al.: J. Andrology, 18, 431 (1997)<br></p>Formula:C7H9N3O3Color and Shape:NeatMolecular weight:183.16Atropine-N-oxide Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Atropine-N-oxide Hydrochloride is an alkaloid. A neuroprotective compound with potential therapeutic efficacy.<br>References Beraki, S., et al.: PLoS One, 8, 69233 (2013); Polonovski, M., et al: Compt. rend., 180, 1755 (1925)<br></p>Formula:C17H23NO4·ClHColor and Shape:NeatMolecular weight:341.83Itraconazole-d5 (major)
CAS:Controlled Product<p>Applications An isotopically labelled, orally active antimycotic structurally related to Ketoconazole.A representative lot was 88% d5, 12% d4 with no d0. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M., et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C352H5H33Cl2N8O4Color and Shape:NeatMolecular weight:710.66(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
CAS:Controlled Product<p>Applications (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-Butanediol (cas# 133775-25-4) is a useful research chemical.<br></p>Formula:C12H13F2N3O2Color and Shape:NeatMolecular weight:269.253-(1H-IMIDAZOL-2-YL)PROPANOIC ACID HCL
CAS:Formula:C6H9ClN2O2Purity:97%Color and Shape:SolidMolecular weight:176.63,5-Didesamino-3,5-dioxo Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity D<br>Applications 3,5-Didesamino-3,5-dioxo Lamotrigine (Lamotrigine EP Impurity D) is an impurity of the anticonvulsant Lamotrigine (L173250).<br>References Hlavac, J. et al.: ARKIVOC, 1, 22 (2003);<br></p>Formula:C9H5Cl2N3O2Color and Shape:NeatMolecular weight:258.06
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