Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10353 products of "Benzimidazole and Imidazole Derivatives"
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N-Ethyl-N-methyl-3-vinylphenyl Carbamate
CAS:Controlled Product<p>Impurity Rivastigmine USP Related Compound F<br>Stability Light Sensitive<br>Applications A related compound of Rivastigmine (R541000), a cholinesterase inhibitor. Rivastigmine USP Related Compound F.<br></p>Formula:C12H15NO2Color and Shape:White SolidMolecular weight:205.252-cyclopropyl-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:158.203994750976562,3-Dichlorobenzoyl Nitrile
CAS:Controlled Product<p>Applications 2,3-Dichlorobenzoyl Nitrile is an impurity of Lamotrigine (L173250), an anticonvulsant that is used in the treatment of bipolar and depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rao, S.N., et al.: Int. J. Pharma. Pharmaceut. Sci., 4, 133 (2012); Qian, Y., et al.: J. Chem. Sci., 121, 463 (2009);<br></p>Formula:C8H3Cl2NOColor and Shape:NeatMolecular weight:200.022-(2,3-Dichlorphenyl)-2-(guanidinylimino)acetonitrile
CAS:Controlled ProductFormula:C9H7Cl2N5Color and Shape:Light YellowMolecular weight:256.09(S)-Modafinil
CAS:Controlled Product<p>Applications Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219 (2002), Dinges, D., et al.: Curr. Med. Res. Opin., 22, 159 (2006)<br></p>Formula:C15H15NO2SColor and Shape:NeatMolecular weight:273.35Letrozole
CAS:<p>Applications A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995),<br></p>Formula:C17H11N5Color and Shape:YellowMolecular weight:285.30Triclabendazole Sulfone
CAS:Controlled Product<p>Applications Triclabendazole Sulfone is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C14H9Cl3N2O3SColor and Shape:Off-WhiteMolecular weight:391.66(4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methanol Hydrochloride
CAS:Controlled ProductFormula:C11H17NO3·HClColor and Shape:NeatMolecular weight:211.26 + 36.46Benznidazole
CAS:<p>Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.<br>References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),<br></p>Formula:C12H12N4O3Color and Shape:NeatMolecular weight:260.25Efinaconazole
CAS:Controlled Product<p>Applications Efinaconazole is a topical antifungal for onychomycosis. (Synonyms: KP-103)<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4OColor and Shape:NeatMolecular weight:348.391-Amino Hydantoin-13C3
CAS:<p>Applications 1-Amino Hydantoin Hydrochloride (A611090), a metabolite of Nitrofuran.Environmental contaminants<br>References Tribalat, L., et al.: Anal. Bioanal. Chem., 386, 2168 (2006), Chu, P., et al.: J. Agric. Food Chem., 55, 2129 (2007),<br></p>Formula:C3H5N3O2Color and Shape:White To Light YellowMolecular weight:118.07Iminodibenzyl 5-Carbonyl Chloride
CAS:Controlled ProductFormula:C15H12ClNOColor and Shape:NeatMolecular weight:257.71(1R)-(-)-10-Camphorsulfonic Acid
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity E (1R)-Isomer<br>Stability Hygroscopic<br>Applications (1R)-(-)-10-Camphorsulfonic Acid (Voriconazole EP Impurity E (1R)-Isomer) is a chiral derivative of Camphor. Used in the preparation of a chiral recognition polymer that is used in the chiral separation of amino acids. A catalyst in direct animation of α-branched aldehydes (including important biological molecules such as α-Me phenylglycine) with near perfect enantioselectivity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, H. et al.: Polym. Preprints Am. Chem. Soc., 40, 506 (1999); Liu, C. et al.: Org. Lett., 13, 2638 (2011);<br></p>Formula:C10H16O4SColor and Shape:WhiteMolecular weight:232.30Omeprazole
CAS:Controlled Product<p>Applications Omeprazole covalently binds to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O3SColor and Shape:White To Light BrownMolecular weight:345.42Benzhydrol-d5
CAS:Controlled Product<p>Applications Intermediate in the preparation of labelled Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Formula:C13D5H7OColor and Shape:NeatMolecular weight:189.26Dibenzazepine-10,11-dione
CAS:Controlled Product<p>Applications Dibenzazepine-10,11-dione is an impurity of Oxcarbazepine (O869250). Dibenzazepine-10,11-dione is used as a reagent in the preparation of bifunctional dipolar electroluminescent template for optoelectronic applications.<br>References Chen, C.-T. et al.: Chem. Comm., 31, 3980 (2005); Heckendorn, R. et al.: Helv, Chim. Acta, 70, 1955 (1987);<br></p>Formula:C14H9NO2Color and Shape:NeatMolecular weight:223.23Oxybutynin-d11 Chloride
CAS:Controlled Product<p>Applications An inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formula:C22D11H20NO3·ClHColor and Shape:NeatMolecular weight:405.024-Hydroxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:Off-WhiteMolecular weight:341.77(aR,bR)-rel-6-Chloro-a-(2,4-difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
CAS:Controlled Product<p>Applications (αR,βR)-rel-6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol is an intermediate in synthesizing rel-(R,R)-Voriconazole (V759990), The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor.<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997)<br></p>Formula:C16H13ClF3N5OColor and Shape:NeatMolecular weight:383.76
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